LOCUS X83425 2402 bp mRNA linear HUM 19-SEP-1995
DEFINITION H.sapiens LU gene for Lutheran blood group glycoprotein.
ACCESSION X83425
VERSION X83425.1
KEYWORDS Lutheran blood group glycoprotein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Parsons S.F., Mawby W.J., Anstee D.J.
TITLE Lutheran blood group glycoprotein is a new member of the
immunoglobulin superfamily of proteins (abstract)
JOURNAL Vox Sang. 67, 1-1(1994).
REMARK (sites)
REFERENCE 2
AUTHORS Parsons S.F., Mallinson G., Holmes C.H., Houlihan J.M.,
Simpson K.L., Mawby W.J., Spurr N.K., Warne D., Barclay A.N.,
Anstee D.J.
TITLE The Lutheran blood group glycoprotein, another member of the
immunoglobulin superfamily, is widely expressed in human tissues
and is developmentally regulated in human liver
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92(12), 5496-5500(1995).
PUBMED 7777537
REFERENCE 3 (bases 1 to 2402)
AUTHORS Parsons S.F.
JOURNAL Submitted (13-DEC-1994) to the INSDC. S.F. Parsons, International
Blood Group Ref. Lab., Southmead Road, Bristol BS10 5ND, UK
FEATURES Location/Qualifiers
source 1..2402
/db_xref="H-InvDB:HIT000323954"
/organism="Homo sapiens"
/chromosome="19"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="Lutheran"
/tissue_type="placenta"
/db_xref="taxon:9606"
sig_peptide 23..115
/citation=[2]
/experiment="experimental evidence, no additional details
recorded"
CDS 23..1909
/gene="LU"
/product="Lutheran blood group glycoprotein"
/function="unknown"
/db_xref="GOA:P50895"
/db_xref="H-InvDB:HIT000323954.12"
/db_xref="HGNC:HGNC:6722"
/db_xref="InterPro:IPR003598"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013106"
/db_xref="InterPro:IPR013162"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036179"
/db_xref="PDB:2PET"
/db_xref="PDB:2PF6"
/db_xref="UniProtKB/Swiss-Prot:P50895"
/citation=[2]
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAA58449.1"
/translation="MEPPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVM
RGKSVILDCTPTGTHDHYMLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPY
QLDSQGRLVLAEAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLS
VMEDSAQEIATCNSRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSL
TSTLYLRLRKDDRDASFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPST
PAGWVREGDTVQLLCRGDGSPSPEYTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGT
YGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTP
ALRWTKDSTPLGDGPMLSLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPEL
KTAEIEPKADGSWREGDEVTLICSARGHPDPKLSWSQLGGSPAEPIPGRQGWVSSSLT
LKVTSALSRDGISCEASNPHGNKRHVFHFGAVSPQTSQAGVAVMAVAVSVGLLLLVVA
VFYCVRRKGGPCCRQRREKGAPPPGEPGLSHSGSEQPEQTGLLMGGASGGARGGSGGF
GDEC"
mat_peptide 116..1906
/gene="LU"
/product="Lutheran blood group glycoprotein"
/function="unknown"
/citation=[2]
/experiment="experimental evidence, no additional details
recorded"
3'UTR 1910..2402
/citation=[2]
/experiment="experimental evidence, no additional details
recorded"
polyA_site 2402
/citation=[2]
/experiment="experimental evidence, no additional details
recorded"
BASE COUNT 426 a 844 c 742 g 390 t
ORIGIN
1 agtctccgcc gccgccgtga acatggagcc cccggacgca ccggcccagg cgcgcggggc
61 cccgcggctg ctgttgctcg cagtcctgct ggcggcgcac ccagatgccc aggcggaggt
121 gcgcttgtct gtacccccgc tggtggaggt gatgcgagga aagtctgtca ttctggactg
181 cacccctacg ggaacccacg accattatat gctggaatgg ttccttaccg accgctcggg
241 agctcgcccc cgcctagcct cggctgagat gcagggctct gagctccagg tcacaatgca
301 cgacacccgg ggccgcagtc ccccatacca gctggactcc caggggcgcc tggtgctggc
361 tgaggcccag gtgggcgacg agcgagacta cgtgtgcgtg gtgagggcag gggcggcagg
421 cactgctgag gccactgcgc ggctcaacgt gtttgcaaag ccagaggcca ctgaggtctc
481 ccccaacaaa gggacactgt ctgtgatgga ggactctgcc caggagatcg ccacctgcaa
541 cagccggaac gggaacccgg cccccaagat cacgtggtat cgcaacgggc agcgcctgga
601 ggtgcccgta gagatgaacc cagagggcta catgaccagc cgcacggtcc gggaggcctc
661 gggcctgctc tccctcacca gcaccctcta cctgcggctc cgcaaggatg accgagacgc
721 cagcttccac tgcgccgccc actacagcct gcccgagggc cgccacggcc gcctggacag
781 ccccaccttc cacctcaccc tgcactatcc cacggagcac gtgcagttct gggtgggcag
841 cccgtccacc ccagcaggct gggtacgcga gggtgacact gtccagctgc tctgccgggg
901 ggacggcagc cccagcccgg agtatacgct tttccgcctt caggatgagc aggaggaagt
961 gctgaatgtg aatctcgagg ggaacttgac cctggaggga gtgacccggg gccagagcgg
1021 gacctatggc tgcagagtgg aggattacga cgcggcagat gacgtgcagc tctccaagac
1081 gctggagctg cgcgtggcct atctggaccc cctggagctc agcgagggga aggtgctttc
1141 cttacctcta aacagcagtg cagtcgtgaa ctgctccgtg cacggcctgc ccacccctgc
1201 cctacgctgg accaaggact ccactcccct gggcgatggc cccatgctgt cgctcagttc
1261 tatcaccttc gattccaatg gcacctacgt atgtgaggcc tccctgccca cagtcccggt
1321 cctcagccgc acccagaact tcacgctgct ggtccaaggc tcgccagagc taaagacagc
1381 ggaaatagag cccaaggcag atggcagctg gagggaagga gacgaagtca cactcatctg
1441 ctctgcccgc ggccatccag accccaaact cagctggagc caattggggg gcagccccgc
1501 agagccaatc cccggacggc agggttgggt gagcagctct ctgaccctga aagtgaccag
1561 cgccctgagc cgcgatggca tctcctgtga agcctccaac ccccacggga acaagcgcca
1621 tgtcttccac ttcggcgccg tgagccccca gacctcccag gctggagtgg ccgtcatggc
1681 cgtggccgtc agcgtgggcc tcctgctcct cgtcgttgct gtcttctact gcgtgagacg
1741 caaagggggc ccctgctgcc gccagcggcg ggagaagggg gctccgccgc caggggagcc
1801 agggctgagc cactcggggt cggagcaacc agagcagacc ggccttctca tgggaggtgc
1861 ctccggagga gccaggggtg gcagcggggg cttcggagac gagtgctgag ccaagaacct
1921 cctagaggct gtccctggac ctggagctgc aggcatcaga gaaccagccc tgctcacgcc
1981 atgcccgccc ccgccttccc tcttccctct tccctctccc tgcccagccc tcccttcctt
2041 cctctgccgg caaggcaggg acccacagtg gctgcctgcc tccgggaggg aaggagaggg
2101 agggtgggtg ggtgggaggg ggccttcctc cagggaatgt gactctccca ggccccagaa
2161 tagctcctgg acccaagccc aaggcccagc ctgggacaag gctccgaggg tcggctggcc
2221 ggagctattt ttacctcccg cctcccctgc tggtcccccc acctgacgtc ttgctgcaga
2281 gtctgacact ggattccccc ccctcacccc gcccctggtc ccactcctgc ccccgcccta
2341 cctccgcccc accccatcat ctgtggacac tggagtctgg aataaatgct gtttgtcaca
2401 tc
//