LOCUS X82209 7568 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for MN1 protein.
ACCESSION X82209
VERSION X82209.2
KEYWORDS MN1 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Deprez R.H.L., Riegman P.H.J., Groen N.A., Warringa U.L.,
Van Biezen N.A., Molijn A.C., Bootsma D., De Jong P.J., Menon A.G.,
Kley N.A., Seizenger B.R., Zwarthoff E.C.
TITLE Cloning and characterization of MN1, a gene from chromosome 22q11,
which is disrupted by a balanced translocation in a meningioma
JOURNAL Oncogene 10(8), 1521-1528(1995).
PUBMED 7731706
REFERENCE 2
AUTHORS Riegmann P.H.J.
JOURNAL Submitted (14-OCT-1994) to the INSDC. P.H.J. Riegmann, Dept of
Pathology, Erasmus University Rotterdam, PO Box 1738, 3000 DR
Rotterdam, NETHERLANDS
REMARK revised by [4]
REFERENCE 3 (bases 1 to 7568)
AUTHORS Gastier J.M., Brody T., Pulido J.C., Businga T., Sunden S., Hu X.,
Maitra S., Buetow K.H., Murray J.C., Sheffield V.C., Boguski M.,
Duyk G.M., Hudson T.J.
TITLE Development of a screening set for new (CAG/CTG)n dynamic mutations
JOURNAL Genomics 32(1), 75-85(1996).
PUBMED 8786123
REFERENCE 4 (bases 1 to 7568)
AUTHORS Riegmann P.H.J.
JOURNAL Submitted (19-AUG-2004) to the INSDC. P.H.J. Riegmann, Dept of
Pathology, Erasmus University Rotterdam, PO Box 1738, 3000 DR
Rotterdam, NETHERLANDS
COMMENT Related sequences: Z28469 and M85938.
FEATURES Location/Qualifiers
source 1..7568
/db_xref="H-InvDB:HIT000323912"
/organism="Homo sapiens"
/map="22q11"
/mol_type="mRNA"
/dev_stage="fetal"
/clone_lib="Clontech HL1065 and Stratagene 936206"
/tissue_type="brain"
/db_xref="taxon:9606"
exon 1..4734
/number=1
CDS 957..4916
/gene="MN1"
/product="MN1 protein"
/db_xref="GOA:Q10571"
/db_xref="H-InvDB:HIT000323912.15"
/db_xref="HGNC:HGNC:7180"
/db_xref="InterPro:IPR037644"
/db_xref="UniProtKB/Swiss-Prot:Q10571"
/protein_id="CAA57693.2"
/translation="MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGP
PGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP
GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQ
GPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE
PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAM
PRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQHGVFFERFSGARKMPVGLEPSVGSRH
PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGL
QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYM
NVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSG
PPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQ
QRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHL
AQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEP
MRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG
GQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSA
SKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGK
RKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDG
TSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPG
VSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGG
AKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV
GAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP
DEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSE
AVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKEAHD
LPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT"
repeat_region 1836..1880
/rpt_unit_range=1836..1838
/rpt_unit_seq="CAG"
repeat_region 2523..2603
/rpt_unit_range=2523..2525
/rpt_unit_seq="CAG"
/note="polymorphic CAG repeat"
exon 4735..7560
/number=2
BASE COUNT 1486 a 2421 c 2177 g 1484 t
ORIGIN
1 gcgcggaggc agggaaccgg agccttggag cgacccaacc cctcgtctcg ctgccctccc
61 gcgcctgcaa cggtgcgcgg agactccggc gaactcagac acccaacggc ggagaacaga
121 agcggcaggc ggcggacgtg gcccggaagc tgcgcgccga acgcagcgca cccgctgccg
181 agcagaggag ccgcgccttt ccccgaccct cggctccagc ccccggcgcc tgccgcctcg
241 cagcccctct gcgtcctcgg ctcgggggcc ggcaccggcg atgccgagcg gacgctccag
301 tcctccgacc cgctgaagaa gcagcagccg ctcgcccgga gcctacgggg attgtgcgag
361 cggatcgtgc tcggtggagg ctcgggctgc ggggcgcggg gactccgggg ggcgggggga
421 gggaccgctc tgtcggtgcc cggcgccagc cgcggctttg aagggtctcc ctcccctgcc
481 cttagcagct ctgccacgga ctccgggagg ctgcgggcgg cgtcctgagg gctccccagc
541 agacccaatc ggacttgaga aggtgatcgc tctgctctcc caaccccctt ccctccccat
601 tccccccact taactttttg tctccgttca tccgcggctt cgtcccctcc ccggcagacc
661 cacccgcggc tgtgacaacc gcccggggca tgggcccccc aacacggctc ctagaggccc
721 cgcggcctcg caagatgtga gaggccctcc ccgggcagaa tcggagcttc aggagaggag
781 ctaatacccc gccccccgtc cctcacatca ggcggggtgg aggtgcgcgc tgagcccccg
841 cggtgctgag cgtcccggag cgcccaatcc tgggctggaa cgagtagctg gccggaggcg
901 cgccgcggag agccggctgt catgccctat tgatccccct ctgccccccg ccaagtatgt
961 ttgggctgga ccaattcgag ccccaggtca acagcaggaa cgctggccag ggcgagagga
1021 actttaacga gaccggactg agcatgaaca cccactttaa ggccccggct ttccacactg
1081 gggggccccc tggccctgtg gatcctgcta tgagcgcgct gggcgaaccc ccgatcttgg
1141 gcatgaacat ggagccctac ggcttccacg cgcgcggcca ctcggagttg cacgcagggg
1201 ggctgcaagc gcagcctgtg cacggcttct ttggcggcca gcagcctcac cacggccacc
1261 cgggaagtca tcatccccac cagcatcacc cccactttgg gggcaacttc ggtggcccgg
1321 accccggggc ctcgtgcctg cacgggggtc gcctgctcgg ctacggcggc gcagccggag
1381 gcctgggcag ccagccgccc ttcgccgagg gctatgagca catggcggag agccaggggc
1441 ctgagagctt cggcccgcag cgaccgggga acctcccgga cttccacagt tcaggtgcct
1501 ccagccacgc cgtgccggcc ccatgcctgc cgctggacca gagccctaac cgagccgcct
1561 ccttccacgg cctgccgtcc tccagcggct ccgattccca cagtctggag ccacggaggg
1621 tgacgaacca aggagccgtc gactcgctgg aatacaatta cccgggcgag gcgccctcgg
1681 gacattttga catgttttcg ccctctgact ccgaagggca gctgcctcat tatgcagcgg
1741 gtcgccaggt tcctgggggc gctttcccgg gcgcctcggc catgcccaga gctgcgggca
1801 tggtgggctt gtccaaaatg cacgcccagc caccgcagca gcagccccag cagcagcagc
1861 agccccagca gcagcagcag catggtgtgt tctttgagag gttcagtggg gccagaaaga
1921 tgcctgtggg tctggagccc tcagtgggct ccaggcaccc gttaatgcag cctccccagc
1981 aggccccgcc accccctcag cagcagcccc cgcagcagcc gccacagcag cagccgccgc
2041 cgccacccgg gcttctagtc cgacaaaatt cgtgcccgcc tgcgctccct cggccccagc
2101 agggcgaggc gggcacgccc agcggcggcc tgcaggacgg aggccccatg ctgcccagcc
2161 agcacgcgca attcgagtat cccatccacc ggctggagaa ccggagcatg cacccttatt
2221 ccgagcctgt tttcagcatg cagcatcctc ctccgcagca ggcgcccaac cagcggctgc
2281 agcatttcga cgcgcccccc tacatgaacg tggccaagag gccgcgcttc gactttccgg
2341 gcagcgcggg agtggaccgc tgcgcttcgt ggaacggcag catgcacaac ggcgctctgg
2401 ataatcacct ctccccttcc gcctacccag gcctacccgg cgagttcaca ccgcctgtgc
2461 ccgacagctt cccttcgggg ccgcccctgc agcatccggc cccggaccac cagtccctgc
2521 aacagcagca gcagcagcag cagcagcagc aacagcagca gcagcagcag caacagcaac
2581 agcaacagca gcagcagcag cagcgccaaa acgcggccct catgattaag cagatggcgt
2641 cgcggaatca gcagcagcgg ctgcgccagc ccaacctggc tcagctaggc caccccgggg
2701 acgtgggcca gggcggcctg gtgcatggcg gcccggtggg cggcttggcc cagccgaact
2761 ttgagcgcga aggcggcagc acgggcgccg ggcgtctggg caccttcgag cagcaggcgc
2821 cgcacttggc gcaagagagc gcgtggttct caggtccgca tccgccgccc ggagacctgc
2881 tgccccgtag gatgggcggc tcgggtctgc ccgctgactg tggcccgcac gaccccagcc
2941 tggcgccccc tcctccgcct ggtggctcgg gggtgctgtt ccggggccct ctgcaggagc
3001 cgatgaggat gcccggagag ggccacgtgc ccgcgctgcc ttcaccgggc ctgcagttcg
3061 ggggcagtct gggaggcctg ggtcagctgc agtcgcccgg ggcgggcgtg gggctcccca
3121 gcgctgcttc ggagcgccgg cccccgccgc cggactttgc tacgtctgcg ctcgggggcc
3181 agccgggctt tccgtttggt gcagccggcc ggcagtccac gccgcacagc ggtccaggcg
3241 tgaactcgcc ccccagcgcg ggagggggcg gtggcagctc tggtggcggc ggtggcgggg
3301 gtgcctaccc gccgcagcct gatttccagc ccagccagcg cacctcggcc agtaaattgg
3361 gcgcgctctc gctgggctcc ttcaacaagc ccagctccaa ggacaacctg ttcggccaga
3421 gctgcctggc tgcgctctcc accgcttgcc agaacatgat cgccagcctc ggggccccca
3481 acctcaacgt gaccttcaac aagaagaacc cgccagaggg caagaggaaa ctgagccaga
3541 acgagaccga cggcgcggca gtggccggca acccgggctc ggattacttc ccaggaggga
3601 ctgctcctgg ggccccagga cccggaggcc cgtccgggac cagtagcagc ggctccaaag
3661 cctcggggcc gcccaaccct ccagcccagg gggacggcac cagcctctcc cccaactaca
3721 ccctggaatc cacgtcgggg aatgacggca agccggtctc cgggggcggc ggccggggac
3781 ggggtcgcag aaaaagggac agtggtcacg tgagccctgg caccttcttt gacaagtact
3841 cggcggctcc ggacagcggg ggcgcacctg gggtgagccc agggcagcag caagcgtcag
3901 gcgcagccgt cgggggaagc tccgcaggcg agacgcgcgg ggcaccgacg ccccacgaaa
3961 aggcgctcac gtcgccatcc tgggggaagg gggctgagtt gctcctgggg gatcagccgg
4021 acctcattgg gtccctggac ggcggggcca agtcggacag tagttcgcca aacgtgggtg
4081 agttcgcctc ggacgaggtg agcacgagct acgccaatga ggacgaggtg tcgtccagct
4141 ctgacaaccc ccaggcacta gttaaagcga gcaggagtcc cctggtgacc ggctcgccca
4201 aactccctcc ccgtggggta ggcgccgggg aacacggacc gaaggcgccc ccgcccgccc
4261 tcggcctggg catcatgtct aactctacct cgacccctga cagctacggc ggcggtgggg
4321 gcccgggcca tccgggcact ccgggcctgg agcaggtccg caccccgacg agcagcagcg
4381 gcgccccgcc acccgacgag atccaccccc tggagatcct tcaggcgcag atccagctac
4441 agaggcagca gttcagcatc tccgaggacc agcctctggg gctgaagggt ggcaagaagg
4501 gtgagtgcgc cgtcggggcc tcaggggcgc agaatggcga cagcgagctg ggcagctgct
4561 gctccgaggc ggtcaagagc gccatgagca ccattgacct ggactcgctg atggcagagc
4621 acagcgctgc ctggtacatg cccgctgaca aggccctggt ggacagcgcg gacgacgaca
4681 agacgttggc gccctgggag aaggccaaac cccagaaccc caacagcaaa gaagcccacg
4741 acctccctgc aaacaaggcc tcagcatccc agcctggcag ccacttgcag tgcctgtctg
4801 tccactgcac agacgacgtg ggtgacgcca aggctcgagc ctccgtgccc acctggcggt
4861 ccctgcattc tgacatctcc aacagatttg ggacattcgt ggctgcccta acttgaatga
4921 caagaaagat cccctcctct accaggccct tcctctcccc ctgtctgttt ccttccccct
4981 caaccttacc ccacccctct gttaatttga aagggccact attgctgagt ggatgagttt
5041 tttttttttc ctctaggttg gtacctgctt agtggcatat ggaccggaaa gggttaattt
5101 aaaggggggg aacctcaaaa gtttttttaa aaaagaaact tgtctgccac agtatgttac
5161 cagtgttaac ccttctgcag ttagcaaact tttgcttaag cctttttcct ctagatactc
5221 cccatgtttc ggtaatcttg gcatacattt tttagatgac ctctttcctt gttttgtttt
5281 catgctgctg tatgtccaag tattgttatt tcataataag acaagagttg ctttcttttt
5341 tattcttttt ccttttctta ccccctcccc ttttattttc tttttgcttt gttcactgct
5401 tattaaaatg gaaatcctgg agaatagtag ttctggaata ttgccgggtg aaagtccaat
5461 tgtcatcaca atgttatata ttgacacccc agtgtcatca gtcaggcagg agccaaacaa
5521 tgaatgcccc tcttaggtat tccgcctggg attttgtttt gtctgttccc taagaaaata
5581 tattttcatt cctgcaaaca cagtgctcag ccttcagttc ccttccactt gagttctctc
5641 ttctcctgct ggaagccgcc cctctctgcg atggacgtga ggacgtgtcc agctctgctc
5701 tgtgggaagg agttggaatg ttcgacagca gtgttttctc tccttttctg ggcctcctcg
5761 caaatgccca ggccctgcat tttcacgctg tgctaagcag cctttggtct gcatggggga
5821 tggtgtgctc ccagcctgca gtctttggag caaggctgct gcccgtgcct tgggtgctgg
5881 agttggagga ggctgttctc agccctttcc cttttctgaa agctgttcct ggccgggcat
5941 cccagggaag aaggagggga ctgcgtgtat ctcctccacc tctcccattc catccccagt
6001 ccagcctggg caaccccacc cctgggaggg atgaggcacc ctcttgctca gcctgctcag
6061 ccttctctga gcctttgcag ggatctgcag actcctgagg gctagaggac agagaaagag
6121 aatagaatga aatgactttg attcctgcgc cttttagttt tgaactctgg aattcctctg
6181 ccccctcccc aacatttttt tggaatctca ccctgttgca aaactagagc catgtcccaa
6241 gcatctcaca aaggaataac tgctctgagc agagatgagt ggtggttggc aggggcaggc
6301 aactttgggt gctgctgatg cctgcaaaag ccatttatgg cttgtggtgg ggggcacata
6361 gattccccgg tgggttagac aggaagtaac tgatatcact tcacccaaat atataaccgt
6421 gatggttatc tatttaattt cagtttttgt taacgagcgt gtcttactaa aacgctccac
6481 tttgagctcc cccaccccct ccaggtcctc agagtttgca gatctgggct ttctaaagca
6541 agtgacctga aggctctggg ctcaccatac aacacccacg ttgtttattt caaagaactt
6601 ttcagcgaag ggagaggagc tttcagaaaa acctcactct ttcccctccc ttctcccctc
6661 tttccttctg ccggtccttt tggctggggt ctgagtctgc ggttctcgcc tgggcagtct
6721 tgacgaggag caaaccccgc cttcagaggg cagacaaagc aggtggcatg aattgatcag
6781 cgagaaaggt gtgagccgag gcagttcctg cgttctgcta caaaaggaat ggaaagggaa
6841 gggaatttcc ccccaccatg ggctgtggga gagttgaccg tattctgggc aagactccat
6901 gacccctctg attctgcagt gtacagctgt ttgagagcct catcatttta cttttgaaac
6961 aggaatgatt tctccttaat tgcttaaggc cggggagcaa agtgtcttaa cttctgtctt
7021 tgactttccc agcgttgagt catcaacact ttgccaatta gctcatggtc ctggcaacct
7081 cagaaacccc tgaagtttta aaaactttct cgctccccac gaccccagaa tgaaacagct
7141 ttaaaaatag ccttaagcaa aaggatgtta tttcattaaa tttggtttaa tggaaagaat
7201 aaaagtaaat gaaaaacaca ccctacacac tagactccga acactggtaa tcagtactgc
7261 atagcaaact ctttgggaaa gaaaacgaaa atgttattgc acatgtaaaa tatgaaaact
7321 taactctgct gtgtgttagg caatcctgta atcttttttg actcttaaaa gaaattcatt
7381 tctgaaatgc ttggttggaa gactgtgaca atagctcatg aaattgagtg ttattttttt
7441 ctttcttttt taaaaaaata tgtaaagtgc agtcttctgt attcctgcat attgtatata
7501 cctgtatatg ttttcctgag cagttaaata acaataaata tgacgttaat ggtgaaaaaa
7561 aaaaaaaa
//