LOCUS X82157 2645 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for high endothelial venule.
ACCESSION X82157
VERSION X82157.1
KEYWORDS hevin gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Girard J.P., Springer T.A.
TITLE Cloning from purified high endothelial venule cells of hevin, a
close relative of the antiadhesive extracellular matrix protein
SPARC
JOURNAL Immunity 2(1), 113-123(1995).
PUBMED 7600298
REFERENCE 2 (bases 1 to 2645)
AUTHORS Girard J.
JOURNAL Submitted (10-OCT-1994) to the INSDC. J. Girard, Center for Blood
Research and Dept. of Pathology, Harvard Medical School, 200
Longwoode Avenue, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2645
/db_xref="H-InvDB:HIT000323906"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone="HEC25"
/cell_line="purified high endothelial cells"
/cell_type="high endothelial cells"
/tissue_type="tonsil"
/db_xref="taxon:9606"
CDS 198..2192
/gene="hevin"
/db_xref="GOA:Q14515"
/db_xref="H-InvDB:HIT000323906.14"
/db_xref="HGNC:HGNC:11220"
/db_xref="InterPro:IPR001999"
/db_xref="InterPro:IPR002048"
/db_xref="InterPro:IPR002350"
/db_xref="InterPro:IPR003645"
/db_xref="InterPro:IPR011992"
/db_xref="InterPro:IPR015369"
/db_xref="InterPro:IPR016359"
/db_xref="InterPro:IPR018247"
/db_xref="InterPro:IPR019577"
/db_xref="InterPro:IPR036058"
/db_xref="UniProtKB/Swiss-Prot:Q14515"
/protein_id="CAA57650.1"
/translation="MKTGLFFLCLLGTAAAIPTNARLLSDHSKPTAETVAPDNTAIPS
LRAEDEENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQGKSSSQELGLKDQED
SDGDLSVNLEYAPSEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTDSNQQESITKR
EENQEQPRNYSHHQLNRSSKHSQGLRDQGNQEQDPNISNGEEEEEKEPGEVGTHNDNQ
ERKTELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEM
EEENASNVNKHIQETEWQSQEGKTGLEAISNHKETEEKTVSEALLMEPTDDGNTTPRN
HGVDDDGDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHLKIEEQREKVHE
NENIGTTEPGEHQEAKKAENSSNEEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQG
KPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGA
CKSIPTCTDFEVIQFPLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKR
LLAGDHPIDLLLRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPME
HCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDENLLF"
sig_peptide 198..260
regulatory 2608..2613
/regulatory_class="polyA_signal_sequence"
BASE COUNT 923 a 516 c 580 g 626 t
ORIGIN
1 gagcagcaga atttcaactc cagtagactt gaatatgcct ctgggcaaag aagcagagct
61 aacgaggaaa gggatttaaa gagtttttct tgggtgtttg tcaaactttt attccctgtc
121 tgtgtgcaga ggggattcaa cttcaatttt tctgcagtgg ctctgagtcc agccccttac
181 ttaaagatct ggaaagcatg aagactgggc tttttttcct atgtctcttg ggaactgcag
241 ctgcaatccc gacaaatgca agattattat ctgatcattc caaaccaact gctgaaacgg
301 tagcacccga caacactgca atccccagtt taagggctga agatgaagaa aatgaaaaag
361 aaacagcagt atccacagaa gacgattccc accataaggc tgaaaaatca tcagtactaa
421 agtcaaaaga ggaaagccat gaacagtcag cagaacaggg caagagttct agccaagagc
481 tgggattgaa ggatcaagag gacagtgatg gtgacttaag tgtgaatttg gagtatgcac
541 catctgaagg tacattggac ataaaagaag atatgagtga gcctcaggag aaaaaactct
601 cagagaacac tgattttttg gctcctggtg ttagttcctt cacagattct aaccaacaag
661 aaagtatcac aaagagagag gaaaaccaag aacaacctag aaattattca catcatcagt
721 tgaacaggag cagtaaacat agccaaggcc taagggatca aggaaaccaa gagcaggatc
781 caaatatttc caatggagaa gaggaagaag aaaaagagcc aggtgaagtt ggtacccaca
841 atgataacca agaaagaaag acagaattgc ccagggagca tgctaacagc aagcaggagg
901 aagacaatac ccaatctgat gatattttgg aagagtctga tcaaccaact caagtaagca
961 agatgcagga ggatgaattt gatcagggta accaagaaca agaagataac tccaatgcag
1021 aaatggaaga ggaaaatgca tcgaacgtca ataagcacat tcaagaaact gaatggcaga
1081 gtcaagaggg taaaactggc ctagaagcta tcagcaacca caaagagaca gaagaaaaga
1141 ctgtttctga ggctctgctc atggaaccta ctgatgatgg taataccacg cccagaaatc
1201 atggagttga tgatgatggc gatgatgatg gcgatgatgg cggcactgat ggccccaggc
1261 acagtgcaag tgatgactac ttcatcccaa gccaggcctt tctggaggcc gagagagctc
1321 aatccattgc ctatcacctc aaaattgagg agcaaagaga aaaagtacat gaaaatgaaa
1381 atataggtac cactgagcct ggagagcacc aagaggccaa gaaagcagag aactcatcaa
1441 atgaggagga aacgtcaagt gaaggcaaca tgagggtgca tgctgtggat tcttgcatga
1501 gcttccagtg taaaagaggc cacatctgta aggcagacca acagggaaaa cctcactgtg
1561 tctgccagga tccagtgact tgtcctccaa caaaacccct tgatcaagtt tgtggcactg
1621 acaatcagac ctatgctagt tcctgtcatc tattcgctac taaatgcaga ctggagggga
1681 ccaaaaaggg gcatcaactc cagctggatt attttggagc ctgcaaatct attcctactt
1741 gtacggactt tgaagtgatt cagtttcctc tacggatgag agactggctc aagaatatcc
1801 tcatgcagct ttatgaagcc aactctgaac acgctggtta tctaaatgag aagcagagaa
1861 ataaagtcaa gaaaatttac ctggatgaaa agaggctttt ggctggggac catcccattg
1921 accttctctt aagggacttt aagaaaaact accacatgta tgtgtatcct gtgcactggc
1981 agtttagtga acttgaccaa caccctatgg atagagtctt gacacattct gaacttgctc
2041 ctctgcgagc atctctggtg cccatggaac actgcataac ccgtttcttt gaggagtgtg
2101 accccaacaa ggataagcac atcaccctga aggagtgggg ccactgcttt ggaattaaag
2161 aagaggacat agatgaaaat ctcttgtttt gaacgaagat tttaaagaac tcaactttcc
2221 agcatcctcc tctgttctaa ccacttcaga aatatatgca gctgtgatac ttgtagattt
2281 atatttagca aaatgttagc atgtatgaca agacaatgag agtaattgct tgacaacaac
2341 ctatgcacca ggtatttaac attaactttg gaaacaaaaa tgtacaatta agtaaagtca
2401 acatatgcaa aatactgtac attgtgaaca gaagtttaat tcatagtaat ttcactctct
2461 gcattgactt atgagataat taatgattaa actattaatg ataaaaataa tgcatttgta
2521 ttgttcataa tatcatgtgc acttcaagaa aatggaatgc tactcttttg tggtttacgt
2581 gtattatttt caatatctta ataccctaat aaagagtcca taaaaatcca aaaaaaaaaa
2641 aaaaa
//