LOCUS X80200 1999 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens MLN62 mRNA.
ACCESSION X80200
VERSION X80200.1
KEYWORDS MLN 62 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1999)
AUTHORS Tomasetto C.
JOURNAL Submitted (25-JUL-1994) to the INSDC. C. Tomasetto, IGBMC, BP 163,
67404 ILLKIRCH Cedex, FRANCE
REFERENCE 2 (bases 1 to 1999)
AUTHORS Tomasetto C., Regnier C.H., Moog-Lutz C., Mattei M.G.,
Chenard M.P., Lidereau R., Basset P., Rio M.C.
TITLE Identification of four novel human genes amplified and
overexpressed in breast carcinoma and localized to the q11-q21.3
region of chromosome 17
JOURNAL Genomics 28(3), 367-376(1995).
PUBMED 7490069
REFERENCE 3 (bases 1 to 1999)
AUTHORS Regnier C.H., Tomasetto C., Moog-Lutz C., Chenard M.P.,
Wendling C., Basset P., Rio M.C.
TITLE Presence of a new conserved domain in CART1, a novel member of the
tumor necrosis factor receptor-associated protein family, which is
expressed in breast carcinoma
JOURNAL J Biol Chem 270(43), 25715-25721(1995).
PUBMED 7592751
REFERENCE 4
AUTHORS Masson R., Regnier C.H., Chenard M.P., Wendling C., Mattei M.G.,
Tomasetto C., Rio M.C.
TITLE Tumor necrosis factor receptor associated factor 4 (TRAF4)
expression pattern during mouse development
JOURNAL Mech. Dev. 71(1-2), 187-191(1998).
PUBMED 9507120
COMMENT Related sequence
X92346 ; Regnier C.H. et al, J.Biol.Chem. 270: 25715-25722, 1995
FEATURES Location/Qualifiers
source 1..1999
/db_xref="H-InvDB:HIT000323797"
/organism="Homo sapiens"
/chromosome="17"
/mol_type="mRNA"
/tissue_type="breast derived metastatic lymph node"
/db_xref="taxon:9606"
misc_feature 18..57
/note="RING finger domain"
CDS 86..1498
/gene="MLN 62, CART1"
/product="cystein rich domain associated to RING and TRAF
protein"
/db_xref="GOA:Q9BUZ4"
/db_xref="H-InvDB:HIT000323797.14"
/db_xref="HGNC:HGNC:12034"
/db_xref="InterPro:IPR001293"
/db_xref="InterPro:IPR001841"
/db_xref="InterPro:IPR002083"
/db_xref="InterPro:IPR008974"
/db_xref="InterPro:IPR012227"
/db_xref="InterPro:IPR013083"
/db_xref="InterPro:IPR017907"
/db_xref="InterPro:IPR018957"
/db_xref="InterPro:IPR027138"
/db_xref="InterPro:IPR037307"
/db_xref="PDB:2EOD"
/db_xref="PDB:2YUC"
/db_xref="PDB:3ZJB"
/db_xref="PDB:4K8U"
/db_xref="PDB:4M4E"
/db_xref="PDB:5YC1"
/db_xref="UniProtKB/Swiss-Prot:Q9BUZ4"
/protein_id="CAA56491.1"
/translation="MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQ
EFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGH
LNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMC
PQESVYCENKCGARMMRGLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLP
VACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKP
HLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFS
PAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLD
QSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNY
VRDDAVFIRAAVELPRKILS"
misc_feature 101..154
/note="CART domain 1"
misc_feature 155..208
/note="CART domain 2"
misc_feature 209..258
/note="CART domain 3"
misc_feature 268..307
/note="alpha helix domain"
misc_feature 308..470
/note="TRAF domain"
polyA_site 1976..1981
BASE COUNT 387 a 591 c 594 g 427 t
ORIGIN
1 gccgggagcg ccgctccagc gaggcgcggg ctgtggggcc gccgcgtgcc tggccccgct
61 cgcccgtgcc ggccgctcgc ccgccatgcc tggcttcgac tacaagttcc tggagaagcc
121 caagcgacgg ctgctgtgcc cactgtgcgg gaagcccatg cgcgagcctg tgcaggtttc
181 cacctgcggc caccgtttct gcgatacctg cctgcaggag ttcctcagtg aaggagtctt
241 caagtgccct gaggaccagc ttcctctgga ctatgccaag atctacccag acccggagct
301 ggaagtacaa gtattgggcc tgcctatccg ctgcatccac agtgaggagg gctgccgctg
361 gagtgggcca ctacgtcatc tacagggcca cctgaatacc tgcagcttca atgtcattcc
421 ctgccctaat cgctgcccca tgaagctgag ccgccgtgat ctacctgcac acttgcagca
481 tgactgcccc aagcggcgcc tcaagtgcga gttttgtggc tgtgacttca gtggggaggc
541 ctatgagagc catgagggta tgtgccccca ggagagtgtc tactgtgaga ataagtgtgg
601 tgcccgcatg atgcgggggc tgctggccca gcatgccacc tctgagtgcc ccaagcgcac
661 tcagccctgc acctactgca ctaaggagtt cgtctttgac accatccaga gccaccagta
721 ccagtgccca aggctgcctg ttgcctgccc caaccaatgt ggtgtgggca ctgtggctcg
781 ggaggacctg ccaggccatc tgaaggacag ctgtaacacc gccctggtgc tctgcccatt
841 caaagactcc ggctgcaagc acaggtgccc taagctggca atggcacggc atgtggagga
901 gagtgtgaag ccacatctgg ccatgatgtg tgccctggtg agccggcaac ggcaggagct
961 gcaggagctt cggcgagagc tggaggagct atcagtgggc agtgatggcg tgctcatctg
1021 gaagattggc agctatggac ggcggctaca ggaggccaag gccaagccca accttgagtg
1081 cttcagccca gccttctaca cacataagta tggttacaag ctgcaggtgt ctgcattcct
1141 caatggcaat ggcagtggtg agggcacaca cctctcactg tacattcgtg tgctgcctgg
1201 tgcctttgac aatctccttg agtggccctt tgcccgccgt gtcaccttct ccctgctgga
1261 tcagagcgac cctgggctgg ctaaaccaca gcacgtcact gagaccttcc accccgaccc
1321 aaactggaag aatttccaga agccaggcac gtggcggggc tccctggatg agagttctct
1381 gggctttggt tatcccaagt tcatctccca ccaggacatt cgaaagcgaa actatgtgcg
1441 ggatgatgca gtcttcatcc gtgctgctgt tgaactgccc cggaagatcc tcagctgagt
1501 gcaggtgggg ttcgagggga aaggacgatg gggcatgacc tcagtcaggc actggctgaa
1561 cttggagagg gggccggacc cccgtcagct gcttctgctg cctaggttct gttaccccat
1621 cctccctccc ccagccacca ccctcaggtg cctccaattg gtgcttcagc cctggcccct
1681 gtggggaaca ggtcttgggg tcatgaaggg ctggaaacaa gtgaccccag ggcctgtctc
1741 ccttcttggg tagggcagac atgccttggt gccggtcaca ctctacacgg actgaggtgc
1801 ctgctcaggt gctatgtccc aagagccata agggggtggg aattggggag ggagaaaggg
1861 tagttcaaag agtctgtctt gagatctgat tttttccccc tttacctagc tgtgccccct
1921 ctggttattt atttccttag tgccaggagg gcacagcagg ggagccctga tttttaataa
1981 atccggaatt gtatttatt
//