LOCUS X79549 3225 bp mRNA linear HUM 11-OCT-1994
DEFINITION H.sapiens AML1 mRNA.
ACCESSION X79549
VERSION X79549.1
KEYWORDS acute myeloid leukemia gene 1; AML1 gene; runt domain.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Levanon D., Negreanu V., Bernstein Y., Bar-Am I., Avivi L.,
Groner Y.
TITLE AML1, AML2, and AML3, the human members of the runt domain
gene-family: cDNA structure, expression, and chromosomal
localization
JOURNAL Genomics 23(2), 425-432(1994).
PUBMED 7835892
REFERENCE 2 (bases 1 to 3225)
AUTHORS Groner Y.
JOURNAL Submitted (06-JUN-1994) to the INSDC. Y. Groner, The Weizmann
Institute, Rehovot, 76100 Israel, ISRAEL
FEATURES Location/Qualifiers
source 1..3225
/db_xref="H-InvDB:HIT000323759"
/organism="Homo sapiens"
/chromosome="21"
/mol_type="mRNA"
/clone_lib="human monocytes cDNA library (T.Miki,NIH)"
/cell_type="monocytes"
/db_xref="taxon:9606"
CDS 1569..2987
/gene="AML1"
/product="acute myeloid leukemia gene no 1"
/db_xref="GOA:Q01196"
/db_xref="H-InvDB:HIT000323759.12"
/db_xref="HGNC:HGNC:10471"
/db_xref="InterPro:IPR000040"
/db_xref="InterPro:IPR008967"
/db_xref="InterPro:IPR012346"
/db_xref="InterPro:IPR013524"
/db_xref="InterPro:IPR013711"
/db_xref="InterPro:IPR016554"
/db_xref="InterPro:IPR027384"
/db_xref="PDB:1CMO"
/db_xref="PDB:1CO1"
/db_xref="PDB:1E50"
/db_xref="PDB:1H9D"
/db_xref="PDB:1LJM"
/db_xref="UniProtKB/Swiss-Prot:Q01196"
/protein_id="CAA56092.1"
/translation="MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKL
RSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTL
VTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVA
TYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAP
TPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPIS
PGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVT
SGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMV
GGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGRHRNSPTNMGGASCSRQARR
DPGPWARTPSWGRGRPTDRISL"
BASE COUNT 675 a 1013 c 841 g 696 t
ORIGIN
1 gcgggcgcgg gcgggacggg cgccccgcgg ccggacccag ccagggcacc acgctgcccg
61 gccctgcgcc gccaggcact tctttccggg gctcctaggg acgccagaag gaagtcaacc
121 tctgctgctt ctccttggcc tgcgttggac cttccttttt ttgttgtttt tttttgtttt
181 tcccctttct tccttttgaa ttaactggct tcttggctgg atgttttcaa cttctttcct
241 ggctgcgaac ttttccccaa ttgttttcct tttacaacag ggggagaaag tgctctgtgg
301 tccgaggcga gccgtgaagt tgcgtgtgcg tggcagtgtg cgtggcagga tgtgcgtgcg
361 tgtgtaaccc gagccgcccg atctgtttcg atctgcgccg cggagccctc cctcaaggcc
421 cgctccacct gctgcggtta cgcggcgctc gtgggtgttc gtgcctcgga gcagctaacc
481 ggcgggtgct gggcgacggt ggaggagtat cgtctcgctg ctgcccgagt cagggctgag
541 tcacccagct gatgtagaca gtggctgcct tccgaagagt gcgtgtttgc atgtgtgtga
601 ctctgcggct gctcaactcc caacaaacca gaggaccagc cacaaactta accaacatcc
661 ccaaacccga gttcacagat gtgggagagc tgtagaaccc tgagtgtcat cgactgggcc
721 ttcttatgat tgttgtttta agattagctg aagatctctg aaacgctgaa ttttctgcac
781 tgagcgtttt gacagaattc attgagagaa cagagaacat gacaagtact tctagctcag
841 cactgctcca actactgaag ctgattttca aggctactta aaaaaatctg cagcgtacat
901 taatggattt ctgttgtgtt taaattctcc acagattgta ttgtaaatat tttatgaagt
961 agagcatatg tatatattta tatatacgtg cacatacatt agtagcacta cctttggaag
1021 tctcagctct tgcttttcgg gactgaagcc agttttgcat gataaaagtg gccttgttac
1081 gggagataat tgtgttctgt tgggacttta gacaaaactc acctgcaaaa aactgacagg
1141 cattaactac tggaacttcc aaataatgtg tttgctgatc gttttactct tcgcataaat
1201 attttaggaa gtgtatgaga attttgcctt caggaacttt tctaacagcc aaagacagaa
1261 cttaacctct gcaagcaaga ttcgtggaag atagtctcca ctttttaatg cactaagcaa
1321 tcggttgcta ggagcccatc ctgggtcaga ggccgatccg cagaaccaga acgttttccc
1381 ctcctggact gttagtaact tagtctccct cctcccctaa ccacccccgc ccccccccac
1441 cccccgcagt aataaaggcc cctgaacgtg tatgttggtc tcccgggagc tgcttgctga
1501 agatccgcgc ccctgtcgcc gtctggtagg agctgtttgc agggtcctaa ctcaatcggc
1561 ttgttgtgat gcgtatcccc gtagatgcca gcacgagccg ccgcttcacg ccgccttcca
1621 ccgcgctgag cccaggcaag atgagcgagg cgttgccgct gggcgccccg gacgccggcg
1681 ctgccctggc cggcaagctg aggagcggcg accgcagcat ggtggaggtg ctggccgacc
1741 acccgggcga gctggtgcgc accgacagcc ccaacttcct ctgctccgtg ctgcctacgc
1801 actggcgctg caacaagacc ctgcccatcg ctttcaaggt ggtggcccta ggggatgttc
1861 cagatggcac tctggtcact gtgatggctg gcaatgatga aaactactcg gctgagctga
1921 gaaatgctac cgcagccatg aagaaccagg ttgcaagatt taatgacctc aggtttgtcg
1981 gtcgaagtgg aagagggaaa agcttcactc tgaccatcac tgtcttcaca aacccaccgc
2041 aagtcgccac ctaccacaga gccatcaaaa tcacagtgga tgggccccga gaacctcgaa
2101 gacatcggca gaaactagat gatcagacca agcccgggag cttgtccttt tccgagcggc
2161 tcagtgaact ggagcagctg cggcgcacag ccatgagggt cagcccacac cacccagccc
2221 ccacgcccaa ccctcgtgcc tccctgaacc actccactgc ctttaaccct cagcctcaga
2281 gtcagatgca ggatacaagg cagatccaac catccccacc gtggtcctac gatcagtcct
2341 accaatacct gggatccatt gcctctcctt ctgtgcaccc agcaacgccc atttcacctg
2401 gacgtgccag cggcatgaca accctctctg cagaactttc cagtcgactc tcaacggcac
2461 ccgacctgac agcgttcagc gacccgcgcc agttccccgc gctgccctcc atctccgacc
2521 cccgcatgca ctatccaggc gccttcacct actccccgac gccggtcacc tcgggcatcg
2581 gcatcggcat gtcggccatg ggctcggcca cgcgctacca cacctacctg ccgccgccct
2641 accccggttc gtcgcaagcg cagggaggcc cgttccaagc cagctcgccc tcctaccacc
2701 tgtactacgg cgcctcggcc ggctcctacc agttctccat ggtgggcggg gagcgctcgc
2761 cgccgcgcat cctgccgccc tgcaccaacg cctccaccgg ctccgcgctg ctcaacccca
2821 gcctcccgaa ccagagcgac gtggtggagg ccgagggcag acacagaaac tcccccacca
2881 acatgggggg ggcctcctgt tcgcgacaag cccgccggga tcccgggccc tgggcccgga
2941 caccgtcctg gggccgaggg cgcccgacgg acaggatctc gctgtaggtc aggcccgcgc
3001 agcctcctgc gcccagaagc ccacgccgcc gccgtctgct ggcgccccgg ccctcgcgga
3061 ggtgtccgag gcgacgcacc tcgagggtgt ccgccggccc cagcacccag gggacgcgct
3121 ggaaagcaaa caggaagatt cccggaggga aactgtgaat gcttctgatt tagcaatgct
3181 gtgaataaaa agaaagattt tatacccttg agaaaaaaaa aaaaa
//