LOCUS X78627 2739 bp mRNA linear HUM 14-DEC-1995
DEFINITION H.sapiens mRNA for translin.
ACCESSION X78627
VERSION X78627.1
KEYWORDS DNA-binding; translin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Aoki K., Suzuki K., Sugano T., Tasaka T., Nakahara K., Kuge O.,
Omori A., Kasai M.
TITLE A novel gene, Translin, encodes a recombination hotspot binding
protein associated with chromosomal translocations
JOURNAL Nat Genet 10(2), 167-174(1995).
PUBMED 7663511
REFERENCE 2 (bases 1 to 2739)
AUTHORS Kasai M.
JOURNAL Submitted (06-APR-1994) to the INSDC. M. Kasai, National Institute
of Health of Japan, Dept of Immunology, 1-32-1, Tokama, Shinjuku,
Tokyo 162, JAPAN
FEATURES Location/Qualifiers
source 1..2739
/db_xref="H-InvDB:HIT000323672"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="DND-41"
/clone="N14"
/cell_line="human leukemia cell line"
/cell_type="lymphoid leukemia"
/db_xref="taxon:9606"
CDS 82..768
/product="translin"
/function="DNA binding protein"
/db_xref="GOA:Q15631"
/db_xref="H-InvDB:HIT000323672.14"
/db_xref="HGNC:HGNC:12379"
/db_xref="InterPro:IPR002848"
/db_xref="InterPro:IPR016068"
/db_xref="InterPro:IPR016069"
/db_xref="InterPro:IPR033956"
/db_xref="InterPro:IPR036081"
/db_xref="PDB:1J1J"
/db_xref="PDB:3PJA"
/db_xref="PDB:3QB5"
/db_xref="PDB:4WYV"
/db_xref="UniProtKB/Swiss-Prot:Q15631"
/protein_id="CAA55341.1"
/translation="MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQG
VHQGAGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLA
AFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVT
AGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFN
KETAAACVEK"
regulatory 2668..2673
/regulatory_class="polyA_signal_sequence"
BASE COUNT 793 a 490 c 608 g 848 t
ORIGIN
1 gattgattgc gctggttgcc tgcggcgtcc acttccttgg ccgcccttgc tacactggct
61 gattgttgtg cagccggcgc catgtctgtg agcgagatct tcgtggagct gcagggcttt
121 ttggctgccg agcaggacat ccgagaggaa atcagaaaag ttgtacagag tttagaacaa
181 acagctcgag agattttaac tctactgcaa ggggtccatc agggtgctgg gtttcaggac
241 attccaaaga ggtgtttgaa agctcgagaa cattttggta cagtaaaaac acatctaaca
301 tctttgaaga ccaaatttcc tgctgaacag tattacagat ttcatgagca ctggaggttt
361 gtgttgcagc gcttggtctt cttggcagca tttgttgtgt atttggaaac agaaacacta
421 gtgactcgag aagcagttac agaaattctt ggcattgagc cagatcggga gaaaggattt
481 catctggatg tagaagatta tctctcagga gttctaattc ttgccagtga actgtcgagg
541 ctgtctgtca acagcgtgac tgctggagac tactcccgac ccctccacat ctccaccttc
601 atcaatgagc tggattccgg ttttcgcctt ctcaacctga aaaatgactc cctgaggaag
661 cgctacgacg gattgaaata tgacgtgaag aaagtagagg aagtggtcta tgatctctcc
721 atccggggct ttaataagga gacggcagca gcttgtgttg aaaaatagga ggctctcctt
781 gctcctggcc ttgctgacct cagcggttgc caggaagggg tgagcacaga gtgcctctta
841 cggtagttag gatgctcagt tgctaaacac tgcgctttat tttcttaacc agttgtggtg
901 tgagtatcag aattgaaaca cttttttggg ggtaaaaaat atagccttta catggacaga
961 attttttttg ttgtttcagt gaatatgcct gtaattcagt gtatttcagt tccgtcagaa
1021 agtgtaaatg ttagtttctt ggtaaagtcc ttttcttgct taccttgact gttgatgtac
1081 tgattgagaa gttcattgtc tcgtttgtga ttcttccaga tgtgatgctt gatattttct
1141 atatgcgagt tagccatcca cacccaggca tagcctggat acagtataaa aatagataat
1201 taaaaagatg gttgccaagc aaggaaaact tattttatat tttcccttcc ttattttaag
1261 cattgtgagt aaatcagatg ttgaattctt ttgccaaggg aattatagct gcaggttctc
1321 tctcactgcc atcaaactgt aaaagattaa actgcgaagt caagctcaac agattatttt
1381 ggaaagtttt tgtattaagg gatttagtaa catcattttg ttttccacca ggcagggagt
1441 agggcttagt gttttaaaac acctctgctt tctgatgttg ccttaatatt ctgctattgc
1501 agcaattaaa aattgtcttc atgtacattt ggaactaaca cgtgatgtga tatattccta
1561 aactatgaaa cctttttcct agtagtcagc tagatcattt gttctgggag tataaagcca
1621 cccacgtaag ttaataagca aaatcctgac tattatgttg ttagagaaaa atgctttgct
1681 ttgtctggaa gaaagataaa atagtgaatt ataaataagt caggccgggc gtggtggctc
1741 acacctgtaa tcccagcaca ctgggaggcc gaggcagggg gactgcttga gctcaggagt
1801 tcgagaccag cctgggcaac aaagtgagac tccatctcta tataaaaaca aaaaccacga
1861 aagcacacac aaaataaatc agtgggattt ggtaatgtgt tttagagtaa gaaatttcag
1921 gttgttggtg actatcccaa cagtcatgtt ttaaatgtac agtttggggc aagtcatgta
1981 aatactgttg gtggtcttcc ccacacgccc caattttcag gtagtactaa gagtatgtgc
2041 caggaaactc ttgctattga attgagatga ttaaaatggt gacttaatcc gtagttattt
2101 tgcacccact gaaaggaaag tgctttccag aataatatga agtatctaaa agtgtcacct
2161 tttcttgcct gatcaacaat ttgggcttcc tgtttgtaca aggggccatt tggcatacct
2221 ttcacagctt ttatcaggcc aagttaaagg ctgactacat tttttcatca tgaggaaagc
2281 agttgaaatg aggcatgagt tactgtgcat tgggatttta gaacaatttt cttgtgacag
2341 ctctttttgt gaagttaggt tcttaaaaga gcccatgatg gtcacttaaa atgtgcagta
2401 atagcactgc caggatcaag catgaaaggc ttttaaatta gatcatccca cagacaatac
2461 gtttgataat agttttttct tttaacctct ttaagtattg attctgcttg agaatattga
2521 agtacttgcc agaagttgtg gatttcagtt ttaacaaatg ctattaaagt ggagaagcac
2581 actctggtct tggaattcca tttgaggatt tagaagtgtc atgtttataa ctattcagtt
2641 gtgtttgttg ctggcttgtt gtaaagcaat aaaatttttt tggtcttttt gtaaaaaaaa
2701 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//