LOCUS X78520 3953 bp mRNA linear HUM 12-JUN-2006
DEFINITION H. sapiens RNA for CLCN3.
ACCESSION X78520
VERSION X78520.1
KEYWORDS chloride channel; chloride channel 3; chloride channel protein;
CLCL3 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Borsani G., Rugarli E.I., Taglialatela M., Wong C., Ballabio A.
TITLE Characterization of a human and murine gene (CLCN3) sharing
similarities to voltage-gated chloride channels and to a yeast
integral membrane protein
JOURNAL Genomics 27(1), 131-141(1995).
PUBMED 7665160
REFERENCE 2 (bases 1 to 3953)
AUTHORS Borsani G.
JOURNAL Submitted (29-MAR-1994) to the INSDC. G. Borsani, Baylor College of
Medicine, Institute for Molecular Genetics, One Baylor Plaza,
Houston, TX 77030, USA
FEATURES Location/Qualifiers
source 1..3953
/db_xref="H-InvDB:HIT000323668"
/organism="Homo sapiens"
/chromosome="4"
/map="4q32"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="cDNA"
/tissue_type="retina"
/db_xref="taxon:9606"
CDS 489..2951
/gene="CLCN3"
/product="chloride channel 3"
/note="putative"
/db_xref="GOA:P51790"
/db_xref="H-InvDB:HIT000323668.13"
/db_xref="HGNC:HGNC:2021"
/db_xref="InterPro:IPR000644"
/db_xref="InterPro:IPR001807"
/db_xref="InterPro:IPR002245"
/db_xref="InterPro:IPR014743"
/db_xref="UniProtKB/Swiss-Prot:P51790"
/protein_id="CAA55280.1"
/translation="MESEQLFHRGYYRNSYNSITSASSDEELLDGAGVIMDFQTSEDD
NLLDGDTAVGTHYTMTNGGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKCKDRE
RHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGI
CLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWA
LSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASG
LSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVL
FSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFP
FILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRL
NTSELIKELFTDCGPLESSSLCDYRNDMNASKIVDDIPDRPAGIGVYSAIWQLCLALI
FKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGA
DCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAF
GREGIYEAHIRLNGYPFLDAKEEFEFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDI
ENMINETSYNGFPVIMSKESQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHT
PSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIIT
KKDILRHMAQTANQDPASIMFN"
CDS 663..2951
/gene="CLCN3"
/product="chloride channel 3"
/note="putative"
/db_xref="GOA:P51790"
/db_xref="HGNC:HGNC:2021"
/db_xref="InterPro:IPR000644"
/db_xref="InterPro:IPR001807"
/db_xref="InterPro:IPR002245"
/db_xref="InterPro:IPR014743"
/db_xref="UniProtKB/Swiss-Prot:P51790"
/protein_id="CAA55281.1"
/translation="MTNGGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKCKDRE
RHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGI
CLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWA
LSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASG
LSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVL
FSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFP
FILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRL
NTSELIKELFTDCGPLESSSLCDYRNDMNASKIVDDIPDRPAGIGVYSAIWQLCLALI
FKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGA
DCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAF
GREGIYEAHIRLNGYPFLDAKEEFEFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDI
ENMINETSYNGFPVIMSKESQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHT
PSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIIT
KKDILRHMAQTANQDPASIMFN"
BASE COUNT 1111 a 766 c 940 g 1136 t
ORIGIN
1 ggggtcacgg gcgaactaga acactgggaa aggggctgca ggttccggac cggaccggcc
61 ctgacccgga ataatgagca aggagggtgt ggtgggttga aagccatcct actttactcc
121 cgagttagag catggattca gttttagtct taagggggaa gtgagattgg agatttttat
181 ttttaatttt gggcagaagc aggttgactc tagggatctc cagagcgaga ggatttaact
241 tcatgttgct cccgtgtttg aaggaggaca ataaaagtcc caccgggcaa aattttcgta
301 acctctgcgg tagaaaacgt caggtatctt ttaaatcgcg atagttttcg ctgtgtcagg
361 ctttcttcgg tggagctccg agggtagcta ggttctaggt ttgaaacaga tgcagaatcc
421 aaaggcagcg caaaaaacag ccaccgattt tgctatgtct ctgagctgcg agataatcag
481 acagctaaat ggagtctgag cagctgttcc atagaggcta ctatagaaac agctacaaca
541 gtataacaag tgcaagtagt gatgaggaac ttttagatgg agcaggtgtt attatggact
601 ttcaaacatc tgaagatgac aatttattag atggtgacac tgcagttgga actcattata
661 caatgacaaa tggaggcagc attaacagtt ctacacattt actggatctt ttggatgaac
721 caattccagg tgttggtaca tatgatgatt tccatactat tgattgggtg cgagaaaaat
781 gtaaagacag agaaaggcat agacggatca acagcaaaaa gaaagaatca gcatgggaaa
841 tgacaaaaag tttgtatgat gcgtggtcag gatggctagt agtaacacta acaggattgg
901 catcaggggc actggccgga ttaatagaca ttgctgccga ttggatgact gacctaaagg
961 agggcatttg ccttagtgcg ttgtggtaca accacgaaca gtgctgttgg ggatctaatg
1021 aaacaacatt tgaagagagg gataaatgtc cacagtggaa aacatgggca gaattaatca
1081 taggtcaagc agagggtcct ggttcttata tcatgaacta cataatgtac atcttctggg
1141 ccttgagttt tgcctttctt gcagtttccc tggtaaaggt atttgctcca tatgcctgtg
1201 gctctggaat tccagagatt aaaactattt taagtggatt catcatcaga ggttacttgg
1261 gaaaatggac tttaatgatt aaaaccatca cattagtcct ggctgtggca tcaggtttga
1321 gtttaggaaa agaaggtccc ctggtacatg ttgcctgttg ctgcggaaat atcttttcct
1381 acctctttcc aaagtatagc acaaacgaag ctaaaaaaag ggaggtgcta tcagctgcct
1441 cagctgcagg ggtttctgta gcttttggtg caccaattgg aggagttctt tttagcctgg
1501 aagaggttag ctattatttt cctctcaaaa ctttatggag atcatttttt gctgctttag
1561 tggctgcatt tgttttgagg tccatcaatc catttggtaa cagccgtctg gtcctttttt
1621 atgtggagta tcatacacca tggtaccttt ttgaactgtt tccttttatt cttctagggg
1681 tatttggagg gctttgggga gcctttttca ttagggcaaa tattgcctgg tgtcgtcgac
1741 gcaagtccac gaaatttgga aagtatcccg ttctggaagt cattattgtt gcagccatta
1801 ctgctgtgat agccttccct aatccataca ctaggctaaa caccagtgaa ctgatcaaag
1861 agctttttac agactgtggt cccctggaat cctcttctct ttgtgactac agaaatgaca
1921 tgaatgccag taaaattgtc gatgacattc ctgatcgtcc agcaggcatt ggagtatatt
1981 cagctatatg gcagttatgc ctggcactca tatttaaaat cataatgaca gtattcactt
2041 ttggcatcaa ggttccatca ggcttgttca tccccagcat ggccattgga gcgatcgcag
2101 gaaggattgt ggggattgcg gtggagcagc ttgcctacta tcaccacgac tggtttatct
2161 ttaaggagtg gtgtgaggtc ggggctgatt gcattacacc tggcctttat gccatggttg
2221 gtgctgctgc atgcttaggt ggtgtgacaa gaatgactgt ctccctggtg gttattgttt
2281 ttgagcttac tggaggcttg gaatatattg ttccccttat ggctgcagtc atgaccagta
2341 aatgggttgg agatgccttt ggcagggaag gcatttatga agcacacatc cgattaaatg
2401 gatacccttt cttggatgca aaagaagaat tcgaattcac tcataccacc ctggctgctg
2461 acgttatgag acctcgaagg aatgatcctc ccttagctgt cctgacacag gacaatatga
2521 cagtggatga tatagaaaac atgattaatg aaaccagcta caatggattt cctgtcataa
2581 tgtcaaaaga atctcagaga ttagtgggat ttgccctcag aagagacctg acaattgcaa
2641 tagaaagtgc caggaaaaaa caagaaggta tcgttggcag ttctcgggtg tgttttgcac
2701 agcacacccc atctcttcca gcagaaagtc ctcggccatt gaagcttcga agcattcttg
2761 acatgagccc ttttacagtg acagaccaca ccccaatgga gattgtggtg gatattttcc
2821 gaaagctggg actgaggcag tgccttgtaa ctcacaatgg gcgcctcctt ggcattataa
2881 caaaaaaaga tatcctccgg catatggccc agacggcaaa ccaagacccc gcttcaataa
2941 tgttcaactg aatctcacag atgaggagag agaagaaacg gaagaggaag tttatttgtt
3001 gaatagcaca actctttaac ctgagggagt catctacttt tttttcctcc tttacaaaaa
3061 aagaaaggaa atataaaagc cgggtttttg caacatggtt tgcaaataat gctggtggaa
3121 tggaggagtt gtttggggag ggaaaggaga gagaaggaaa ggagtgaggt atttcccgtc
3181 taacagaaag cagcgtatca actcctattg ttctgcactg gatgcattca gctgaggatg
3241 tgcctgatag tgcaggcttg cgcctcaaca gagatgacag cagagtcctc gagcacctgg
3301 cctgtttgct cacatgcaag acacatacag ccctattcta gaggatactt gaatggacct
3361 ctataaacgc aaggttcttg ccttttttta atcaaaactg ttctgtttaa ttcatgaatt
3421 gtatagttaa gcattacctt tctacattcc agaagagcct ttatttctct ctctctctct
3481 ctctctctct ctctctctac tgagctgtaa caaagcctct ttaaatcggt gtatcctttt
3541 gaagcagtcc tttctcatat tgagatgtac tgtgatttta ctgaggtttc atcacaagaa
3601 gggagtgttt cttgtgccat taaccatgta gtttgtacca tcactaaatg cttggaacag
3661 tacacatgca ccacaacaaa ggctcatcaa acaggtaaag tctcgaagga agcgagaacg
3721 aaatctctca ttgtgtgccg tgtggctcaa aaccgaaaac aatgaagctt ggttttaaag
3781 gataaagttt tcttttttgt tttcctctca gactttatgg ataatgtgac cgggtcttat
3841 gcaaattttc tatttctaaa actactacta tgatatacaa gtgctgttga gcataattaa
3901 ataaaatgct gctgctttga cagtaaagag aaggaagtat tctgaaaaaa aac
//