LOCUS X77383 1647 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for cathepsin-O.
ACCESSION X77383
VERSION X77383.1
KEYWORDS cathepsin O.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Velasco G., Ferrando A.A., Puente X.S., Sanchez L.M., Lopez-Otin C.
TITLE Human cathepsin O. Molecular cloning from a breast carcinoma,
production of the active enzyme in Escherichia coli, and expression
analysis in human tissues
JOURNAL J Biol Chem 269(43), 27136-27142(1994).
PUBMED 7929457
REFERENCE 2 (bases 1 to 1647)
AUTHORS Lopez-Otin C.
JOURNAL Submitted (28-JAN-1994) to the INSDC. C. Lopez-Otin, Universidad de
Oviedo, Dept de Biologia Funcional, Area de Bioquimica, Facultad de
Medicina, C/Julian Claveria S/N, 33006 Oviedo, SPAIN
FEATURES Location/Qualifiers
source 1..1647
/db_xref="H-InvDB:HIT000323619"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="O7-7"
/tissue_type="breast carcinoma"
/db_xref="taxon:9606"
CDS 50..1015
/product="cathepsin O"
/db_xref="GOA:P43234"
/db_xref="H-InvDB:HIT000323619.12"
/db_xref="HGNC:HGNC:2542"
/db_xref="InterPro:IPR000169"
/db_xref="InterPro:IPR000668"
/db_xref="InterPro:IPR025660"
/db_xref="InterPro:IPR038765"
/db_xref="InterPro:IPR039417"
/db_xref="UniProtKB/Swiss-Prot:P43234"
/protein_id="CAA54562.1"
/translation="MDVRALPWLPWLLWLLCRGGGDADSRAPFTPTWPRSREREAAAF
RESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMS
IPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQV
IDCSYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKG
YSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGF
DKTGSTPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV"
BASE COUNT 456 a 328 c 403 g 460 t
ORIGIN
1 gaattccgga aaacaggccg cgcgggcggc agaggagccg ggcgccgcaa tggacgtgcg
61 ggcgctgccg tggctgccgt ggctgctgtg gctgctgtgc cggggcggcg gcgatgcgga
121 ctcccgcgcc cccttcaccc cgacctggcc gcggagccgc gagcgtgaag ccgccgcctt
181 ccgggaaagt cttaatagac atcgatactt gaattcttta tttcccagtg aaaactccac
241 cgccttctat ggaataaatc agttttccta tttgtttcct gaagagttta aagccattta
301 tttaagaagc aaaccttcca agtttcccag atactcagca gaagtacata tgtccatccc
361 caatgtgtct ttgccgttaa gatttgactg gagggacaag caggttgtga cacaagtgag
421 aaaccagcag atgtgtggag gatgctgggc cttcagcgtg gtgggggcag tggaatctgc
481 ttatgcaata aaggggaagc ccctggaaga cctaagtgtc cagcaggtca ttgactgttc
541 gtataataat tatggctgca atggaggctc tactctcaat gctttgaact ggttaaacaa
601 gatgcaagta aaactggtga aagattcaga atatcctttt aaagcacaaa atggtctgtg
661 ccattacttt tctggttcac attctggatt ttcaatcaaa ggttattctg catatgactt
721 cagtgaccaa gaagatgaaa tggcaaaagc acttcttacc tttggccctt tggtagtcat
781 agtagatgca gtgagctggc aagattatct gggaggcatt atacagcatc actgctctag
841 tggagaagca aatcatgcag ttctcataac tgggtttgat aaaacaggaa gcactccata
901 ttggattgtg cggaattcct ggggaagttc ttggggagta gatggttatg cccatgtcaa
961 aatgggaagt aatgtttgtg gtattgcaga ttccgtttct tctatatttg tgtgacatgt
1021 tgggcagatc aagagacagc tacaaaaatg aaggttttca taatgcaatg taacatagta
1081 cttcaaagta ttattcaact tcaagtttca gcaactacct acaaaagatt ctaaggccta
1141 gtagtattta aactaagttt cagaatgttc ccttcttgta gagagatgga caaccaaagt
1201 cagtgggaca aactccagca cagaagcctg cgaggaagcc tatggaatag tttcctgtcc
1261 tgagacgaaa ttcagattag gagatatttt aggcccctgc aactggggaa ggctactgtt
1321 tgtttttgtt tgcttattat ttatttgttt gtttattgtg agatatttca ggtgggatca
1381 aagaggtcat aagaatttat tttcttttgt ggggtgtaac tactagcttt agattacccc
1441 tatacacaag aatggccaac ctaaaattat gtgtgtcttg tacagttagt tatattagca
1501 gccctctgag atggcgtatc tatcggaagg atttcaaaca ccaattgctt tacctgaaca
1561 aatggtgctt accctttgaa cagcagagtg accacgtaga aggaaggaaa agggcaaaat
1621 cgcttcagtt aaactgaaac cgaattc
//