LOCUS X77197 3214 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for chloride channel.
ACCESSION X77197
VERSION X77197.1
KEYWORDS chloride channel; CLCN4 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS van Slegtenhorst M.A., Bassi M.T., Borsani G., Wapenaar M.C.,
Ferrero G.B., de Conciliis L., Rugarli E., Grillo A., Franco B.,
Zoghbi H.Y., Ballabio A.
TITLE A gene from the Xp22.3 region shares homology with voltage-gated
chloride channels
JOURNAL Hum. Mol. Genet. 3(4), 547-552(1994).
PUBMED 8069296
REFERENCE 2 (bases 1 to 3214)
AUTHORS Borsani G.
JOURNAL Submitted (22-JAN-1994) to the INSDC. G. Borsani, Baylor College of
Medicine, Institute for Molecular Genetics Rm S911, One Baylor
Plaza, Houston, TX 77030, USA
FEATURES Location/Qualifiers
source 1..3214
/db_xref="H-InvDB:HIT000323612"
/organism="Homo sapiens"
/chromosome="X"
/map="Xp22.3"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="adult retina cDNA library"
/clone="4A"
/tissue_type="retina"
/db_xref="taxon:9606"
CDS 384..2666
/gene="CLCN4"
/product="chloride channel"
/db_xref="GOA:P51793"
/db_xref="H-InvDB:HIT000323612.14"
/db_xref="HGNC:HGNC:2022"
/db_xref="InterPro:IPR000644"
/db_xref="InterPro:IPR001807"
/db_xref="InterPro:IPR002246"
/db_xref="InterPro:IPR014743"
/db_xref="UniProtKB/Swiss-Prot:P51793"
/protein_id="CAA54417.1"
/translation="MVNAGAMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTD
RHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGV
CLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWA
LLFAFLAVSLVRVFAPYRCGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSG
LSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVL
FSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFP
FILLGVFGGLWGTLFIRCNIAWCRRRKTTRLGKYPVLEVIVVTAITAIIAYPNPYTRQ
STSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALI
FKIVVTIFTFGMKIPSGLFIPSMAVGAIAGRMVGIGVEQLAYHHHDWYYFRNWCRPGA
DCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAF
GKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVET
LIKETDYNGFPVVVSRDSERLIGFAQRRELILAINNARQRQEGIVSNSIMYFTEEPPE
LPANSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKK
DVLRHMAQMANQDPESIMFN"
regulatory 3175..3181
/regulatory_class="polyA_signal_sequence"
BASE COUNT 745 a 803 c 914 g 752 t
ORIGIN
1 ccgagaggca aatgagcttg tcagtttctg cctccattag accctcaacc caaaggagca
61 ggagatttcg gtagcgtttt aactttatct cagaatctga aagcggaagg ccaggcaagc
121 tgcacacatc aagcgaaacg cctgaggggc ggccagcgcg agggtttctg gccatcgacc
181 ctcacctccc gggacttcca gggtcttccc cccaccccgc gcacacctcc ctgcctcgcc
241 ccgagggcgt cacgtggcag cgtggggccc gcctcctggt gatgtcacgg cgctcgcagc
301 cgtcgcgctg aagaaaggat gctcgaggat gctgtccagg tgggcggccg cgggcgcgat
361 gcggcactgc aggtgtaatt agcatggtca atgcgggagc gatgagtggc tctggaaacc
421 tgatggattt cctcgatgag ccgttccctg atgtggggac gtatgaggac ttccacacca
481 tcgactggct aagggaaaag tcacgggaca ccgacagaca caggaagatc accagcaaga
541 gcaaggagtc catatgggag ttcatcaaga gcctgctgga tgcctggtcg ggatgggtgg
601 tgatgctgct catcggcctg ctggcgggca ccttggctgg ggtcatcgat ctcgccgtgg
661 actggatgac ggacctgaag gagggggtct gcctgtctgc cttctggtat agccatgagc
721 agtgttgctg gacttctaac gagaccactt ttgaggacag agacaagtgt cccctgtggc
781 agaaatggtc ggagctgctg gtgaatcagt cagagggtgc cagtgcttac attctgaatt
841 acttaatgta catcctatgg gcgctgctgt ttgcattttt ggctgtctcc ctggtgcgtg
901 tatttgcacc atatcgctgt ggctctggca taccagagat aaagaccatt ttgagcggct
961 ttatcatcag gggctacttg gggaagtgga ccctgctaat caagacagtc acgctggtgc
1021 tggtagtgtc ctccggtctg agccttggga aggaagggcc gctagtgcac gtggcttgtt
1081 gctgtggcaa cttcttcagc agccttttct ccaagtacag caagaatgag ggcaagaggc
1141 gggaggtgct ttcagctgca gcggctgctg gagtctctgt tgcctttggt gcaccaattg
1201 gaggcgtgct tttcagtcta gaagaggtca gttactactt tcccctgaag accttgtgga
1261 ggtcattttt cgcagccctg gtggcggcct ttacgctgag atccatcaat ccctttggga
1321 atagccgtct cgttctcttt tatgtggaat accacacgcc ctggtacatg gctgaactct
1381 tccccttcat cctgcttggg gtcttcgggg gcttgtgggg aaccctcttc atccgctgca
1441 acatcgcctg gtgcaggagg cgcaagacca ccaggctggg gaagtacccg gtgctggagg
1501 tcattgtggt gactgccatc actgccatca ttgcctaccc caatccctac acacgccaga
1561 gcaccagcga gctcatttct gagctgttca atgactgtgg agcccttgag tcttcccagc
1621 tctgtgacta catcaatgac cccaacatga ctcggcctgt ggatgacatt ccagaccggc
1681 cggctggtgt cggtgtttac acggccatgt ggcagctggc cctggcactg atcttcaaaa
1741 tcgtcgttac catatttacc tttggcatga agatcccgtc gggcctcttc atccccagca
1801 tggctgtggg cgcgatagcg ggcaggatgg tgggaattgg cgtggagcag ctggcctacc
1861 atcaccatga ctggtactac ttcaggaact ggtgcagacc cggtgcagac tgtgtcacgc
1921 cagggctgta cgcaatggtg ggagctgcgg cctgcctcgg tggagttacc aggatgacgg
1981 tgtcattggt ggtcatcatg tttgaattaa ccgggggtct ggagtacatc gtgcccctga
2041 tggcggcggc tgtgaccagc aagtgggtag ctgatgcatt tgggaaagaa ggcatctacg
2101 aggcccacat ccacttaaat gggtaccctt tccttgacgt gaaggacgag tttactcacc
2161 gcacactggc caccgacgtc atgcggcccc ggcggggaga gccgccactg tcggtgctca
2221 cccaggacag catgactgtc gaggacgtgg agacgctcat caaggagacc gactacaacg
2281 gcttccccgt ggtggtctcc agagactccg agcgcctcat tggatttgcc cagaggaggg
2341 aactgattct cgcaataaat aacgccagac agaggcagga gggcattgtg agcaattcca
2401 tcatgtactt cacggaggaa ccccccgagc tgccggccaa cagcccacat cccctgaagc
2461 tgcggcgcat cctgaacctc agcccgttta cagtgacaga ccacactccg atggaaacgg
2521 tggtggatat cttccggaaa ctggggcttc ggcagtgcct ggtgacgcgg agcgggagac
2581 ttcttggcat catcacaaaa aaggatgttc tgagacatat ggcccagatg gcaaaccagg
2641 accccgaatc catcatgttt aattagcaac aaggtggcaa ttattttcag aaaaacactg
2701 actgtgtcat ttaaaaagaa ataaatgata tgttattatc ccaatgaaag atcatgcatt
2761 ggggacagca gaaacaaaag cttttttgga aaggcgggga agaaggatga aacctttaaa
2821 aacaaaaaca aaaacatcaa tgagtaggca ttttatagct ttaaccccgt atgagtttca
2881 agctgtgttt cctaatgagt ttgctactgc tgtgggggca tgtgggtggg taaatgatgt
2941 aaatgatgtg atctgtacaa gtatgtggag catgaatgct gactcaagaa acttttactc
3001 cttctgctca aggctgatgt ttgtaactta tgaacacacg tgaagtgttg agtccaaaag
3061 acaaaggggc atcggcatgt cagcgtcctt atttattggt tcttgaagtt ttgctgctat
3121 gttactgaat catactaaag acatttgcgc ttactttgtt gaaaaagaaa aagaaattaa
3181 atttgaacac agtgaaagct gcaaaaaaaa aaaa
//