LOCUS X76786 1464 bp DNA linear HUM 04-NOV-1998
DEFINITION H.sapiens histamine H1 receptor gene.
ACCESSION X76786
VERSION X76786.1
KEYWORDS histamine H1 receptor; membrane associated protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS DeBacker M.D., Gommeren W., Moereels H., Nobels G., VanGompel P.,
Leysen J.E., Luyten W.H.M.L.
TITLE Genomic cloning, heterologous expression and pharmacological
characterization of a human histamin receptor.
JOURNAL Biochem. Biophys. Res. Commun. 197(3), 1601-1608(1993).
PUBMED 8280179
REFERENCE 2 (bases 1 to 1464)
AUTHORS De Backer M.D.
JOURNAL Submitted (16-DEC-1993) to the INSDC. M.D. De Backer, Janssen
Pharmaceutica n.v., Turnhoutseweg 30, 2340 Beerse, BELGIUM
FEATURES Location/Qualifiers
source 1..1464
/db_xref="H-InvDB:HIT000398804"
/organism="Homo sapiens"
/isolate="healthy volunteer R.W."
/mol_type="genomic DNA"
/haplotype="diploid"
/dev_stage="adult"
/clone_lib="lambda EMBL3/ genomic cDNA"
/clone="17.2"
/sub_clone="4kbBam/pUC18, 0.5kbBam /pUC18"
/tissue_type="white blood cells"
/db_xref="taxon:9606"
CDS 1..1464
/product="histamine H1 receptor"
/db_xref="GOA:P35367"
/db_xref="H-InvDB:HIT000398804.7"
/db_xref="HGNC:HGNC:5182"
/db_xref="InterPro:IPR000276"
/db_xref="InterPro:IPR000921"
/db_xref="InterPro:IPR017452"
/db_xref="PDB:3RZE"
/db_xref="UniProtKB/Swiss-Prot:P35367"
/protein_id="CAA54182.1"
/translation="MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGL
NLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLF
WLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVI
PILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVR
QHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSP
SQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVAVNRSHGQLKTD
EQGLNTHGASEISEDQMLGDSQSFSRTDSDTTTETAPGKGKLRSGSNTGLDYIKFTWK
RLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLH
MFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIRS"
BASE COUNT 352 a 406 c 359 g 347 t
ORIGIN
1 atgagcctcc ccaattcctc ctgcctctta gaagacaaga tgtgtgaggg caacaagacc
61 actatggcca gcccccagct gatgcccctg gtggtggtcc tgagcactat ctgcttggtc
121 acagtagggc tcaacctgct ggtgctgtat gccgtacgga gtgagcggaa gctccacact
181 gtggggaacc tgtacatcgt cagcctctcg gtggcggact tgatcgtggg tgccgtcgtc
241 atgcctatga acatcctcta cctgctcatg tccaagtggt cactgggccg tcctctctgc
301 ctcttttggc tttccatgga ctatgtggcc agcacagcgt ccattttcag tgtcttcatc
361 ctgtgcattg atcgctaccg ctctgtccag cagcccctca ggtaccttaa gtatcgtacc
421 aagacccgag cctcggccac cattctgggg gcctggtttc tctcttttct gtgggttatt
481 cccattctag gctggaatca cttcatgcag cagacctcgg tgcgccgaga ggacaagtgt
541 gagacagact tctatgatgt cacctggttc aaggtcatga ctgccatcat caacttctac
601 ctgcccacct tgctcatgct ctggttctat gccaagatct acaaggccgt acgacaacac
661 tgccagcacc gggagctcat caataggtcc ctcccttcct tctcagaaat taagctgagg
721 ccagagaacc ccaaggggga tgccaagaaa ccagggaagg agtctccctg ggaggttctg
781 aaaaggaagc caaaagatgc tggtggtgga tctgtcttga agtcaccatc ccaaaccccc
841 aaggagatga aatccccagt tgtcttcagc caagaggatg atagagaagt agacaaactc
901 tactgctttc cacttgatat tgtgcacatg caggctgcgg cagaggggag tagcagggac
961 tatgtagccg tcaaccggag ccatggccag ctcaagacag atgagcaggg cctgaacaca
1021 catggggcca gcgagatatc agaggatcag atgttaggtg atagccaatc cttctctcga
1081 acggactcag ataccaccac agagacagca ccaggcaaag gcaaattgag gagtgggtct
1141 aacacaggcc tggattacat caagtttact tggaagaggc tccgctcgca ttcaagacag
1201 tatgtatctg ggttgcacat gaaccgcgaa aggaaggccg ccaaacagtt gggttttatc
1261 atggcagcct tcatcctctg ctggatccct tatttcatct tcttcatggt cattgccttc
1321 tgcaagaact gttgcaatga acatttgcac atgttcacca tctggctggg ctacatcaac
1381 tccacactga accccctcat ctaccccttg tgcaatgaga acttcaagaa gacattcaag
1441 agaattctgc atattcgctc ctaa
//