LOCUS X76013 2437 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens QRSHs mRNA for glutaminyl-tRNA synthetase.
ACCESSION X76013
VERSION X76013.1
KEYWORDS glutaminyl-tRNA synthetase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Lamour V., Quevillon S., Diriong S., N'Guyen V.K., Lipinski M.,
Mirande M.
TITLE Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme
as a case of horizontal gene transfer
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 91(18), 8670-8674(1994).
PUBMED 8078941
REFERENCE 2 (bases 1 to 2437)
AUTHORS Lipinski M.
JOURNAL Submitted (02-NOV-1993) to the INSDC. M. Lipinski, Lab. de Biologie
des Tumeurs Humaines, CNRS URA 1156, Inst. Gustave Roussy, 94805
Villeuif Cedex, FRANCE
FEATURES Location/Qualifiers
source 1..2437
/db_xref="H-InvDB:HIT000323559"
/organism="Homo sapiens"
/chromosome="3"
/mol_type="mRNA"
/clone_lib="fetal brain and liver"
/clone="cDD4 and F27"
/cell_line="IARC-EW11"
/tissue_type="Ewing tumour"
/germline
/db_xref="taxon:9606"
CDS 6..2333
/gene="QRSHs"
/product="glutaminyl-tRNA synthetase"
/db_xref="GOA:P47897"
/db_xref="H-InvDB:HIT000323559.13"
/db_xref="HGNC:HGNC:9751"
/db_xref="InterPro:IPR000924"
/db_xref="InterPro:IPR001412"
/db_xref="InterPro:IPR004514"
/db_xref="InterPro:IPR007638"
/db_xref="InterPro:IPR007639"
/db_xref="InterPro:IPR011035"
/db_xref="InterPro:IPR014729"
/db_xref="InterPro:IPR020056"
/db_xref="InterPro:IPR020058"
/db_xref="InterPro:IPR020059"
/db_xref="InterPro:IPR042558"
/db_xref="InterPro:IPR042559"
/db_xref="PDB:4R3Z"
/db_xref="PDB:4YE6"
/db_xref="PDB:4YE8"
/db_xref="PDB:4YE9"
/db_xref="UniProtKB/Swiss-Prot:P47897"
/protein_id="CAA53600.1"
/translation="MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTL
GSTIDKATGILLYGLASRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPI
DTVDFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWA
DGKMIKNEVDMQVLHLLGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTL
SLMEQLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGIL
HIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTY
ASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEESLLLFEAMRK
GKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEH
ITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAV
RDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAP
RAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEEPE
PGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVS
QPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDK
FQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV"
regulatory 2404..2409
/regulatory_class="polyA_signal_sequence"
BASE COUNT 576 a 665 c 670 g 526 t
ORIGIN
1 ctgcaatggc ggctctagac tccctgtcgc tcttcactag cctcggcctg agcgagcaga
61 aggcccgcga gacgctcaag aactcggctc tgagcgcgca gctgcgcgag gccgctactc
121 aggctcagca gaccctgggt tccaccattg acaaagctac cgggatcctg ttatatggct
181 tggcctcccg actcagggat acccggcgtc tctccttcct tgtaagctac atagccagta
241 agaagatcca cactgagccc cagctaagcg ctgcccttga gtatgtgcgg agtcacccct
301 tggaccccat cgacactgtg gacttcgagc gggaatgtgg cgtgggtgtc attgtgaccc
361 cagagcagat tgaggaggct gtggaggctg ctattaacag gcaccggccc cagctcctgg
421 tggaacgtta ccatttcaac atggggctgc tgatgggaga ggctcgggct gtgctgaagt
481 gggcagatgg caaaatgatc aagaatgaag tggacatgca ggtcctccac cttctgggcc
541 ccaagttgga ggctgatctg gagaagaagt tcaaggtggc aaaagctcgg ctagaagaaa
601 cagaccggag gacggcaaag gatgtggtgg agaatggcga gactgctgac cagaccctgt
661 ctctgatgga gcagctccgg ggggaggccc ttaagttcca caagcctggt gagaactaca
721 agaccccagg ctatgtggtc actccacaca ccatgaatct actaaagcag cacctggaga
781 ttactggtgg gcaggtacgt acccggttcc cgccagaacc caatggaatc ctgcatattg
841 gacatgccaa agccatcaat ttcaactttg gctatgccaa ggccaacaat ggcatctgtt
901 ttctgcgttt tgatgacacc aaccctgaga aggaggaagc aaagttcttc acggccatct
961 gtgacatggt agcctggcta ggctacacac cttacaaagt cacatatgcg tctgactatt
1021 ttgaccagct atatgcgtgg gctgtggagc tcatccgcag gggtctggct tatgtgtgcc
1081 accagcgagg agaggagctc aaaggccata atactctgcc ttcaccctgg agagaccgtc
1141 ccatggagga gtcactgctg ctctttgagg caatgcgcaa gggcaagttt tcagagggcg
1201 aggccacact acggatgaag ctggtgatgg aggatggcaa gatggaccct gtagcctatc
1261 gagtcaagta tacaccacac caccgcacag gggacaaatg gtgcatctat cccacctacg
1321 actacacaca ctgcctctgt gactccatcg agcacatcac tcactcactc tgcaccaagg
1381 aattccaggc ccgacgctct tcctacttct ggctttgcaa tgcactggac gtctattgcc
1441 ctgtgcagtg ggagtatggc cgcctcaacc tgcactatgc tgttgtctct aagaggaaga
1501 tcctccagct tgtagcaact ggtgctgtgc gggactggga tgacccacgg ctctttacac
1561 tcacggccct gcgacggcgg ggcttcccac ctgaggccat caacaacttc tgtgcccggg
1621 tgggagtgac tgtggcacaa accacaatgg agccacatct tctagaagcc tgtgtgcgtg
1681 atgtgctgaa tgacacagcc ccacgagcca tggctgtgct ggagtcacta cgggtcatca
1741 tcaccaactt tcctgctgcc aagtccttgg acatccaggt gcccaacttc ccagctgatg
1801 agaccaaagg cttccatcag gttccctttg cacccattgt cttcattgag aggactgact
1861 tcaaggagga gccagagcca ggatttaagc gcctggcttg gggccagcct gtgggcctga
1921 ggcatacagg ctacgtcatt gagctgcagc atgttgtcaa gggccccagt ggttgtgtag
1981 agagtctgga ggtgacctgc agacgggcag atgctggaga gaagccaaag gcctttattc
2041 actgggtgtc acagcctttg atgtgtgagg ttcgcctcta tgagcgacta ttccagcaca
2101 agaaccctga agatcctact gaggtgcctg gtggattttt aagtgacctg aacctggcat
2161 cactacacgt ggtggatgca gcattagtgg actgctctgt ggccctggca aaacccttcg
2221 acaagttcca gtttgagcgt cttggatatt tctccgtgga tccagacagc catcagggaa
2281 agcttgtctt taaccgaact gtcacactga aggaagaccc aggaaaggtg tgagctggaa
2341 gcactgaacc tacctcatcc tcctggaggg tgtggctacc ctcgccaccc caaattccat
2401 gtcaataaag aacagctaaa ttctcctaga aaaaaaa
//