LOCUS X75500 3330 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for microsomal triglyceride transfer protein.
ACCESSION X75500
VERSION X75500.1
KEYWORDS microsomal triglyceride transfer protein; MTP gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Shoulders C.C., Brett D.J., Bayliss J.D., Narcisi T.M.E.,
Jarmuz A., Grantham T.T., Leoni P.R.D., Bhattacharya S.,
Pease R.J., Cullen P.M., Levi S., Byfield P.G.H., Purkiss P.,
Scott J.
TITLE Abetalipoproteinemia is caused by defects of the gene encoding the
97 kDa subunit of a microsomal triglyceride transfer protein
JOURNAL Hum. Mol. Genet. 2(12), 2109-2116(1993).
PUBMED 8111381
REFERENCE 2 (bases 1 to 3330)
AUTHORS Shoulders C.C.
JOURNAL Submitted (02-NOV-1993) to the INSDC. C.C. Shoulders, Hammersmith
Hospital, Molecular Medicine, Ducane Rd., London W12 OHS, UK
FEATURES Location/Qualifiers
source 1..3330
/db_xref="H-InvDB:HIT000323529"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_type="small intestine"
/db_xref="taxon:9606"
CDS 25..2709
/gene="MTP"
/product="microsomal triglyceride transfer protein, 97kDa
subunit"
/db_xref="GOA:P55157"
/db_xref="H-InvDB:HIT000323529.14"
/db_xref="HGNC:HGNC:7467"
/db_xref="InterPro:IPR001747"
/db_xref="InterPro:IPR011030"
/db_xref="InterPro:IPR015816"
/db_xref="InterPro:IPR015819"
/db_xref="InterPro:IPR039988"
/db_xref="UniProtKB/Swiss-Prot:P55157"
/protein_id="CAA53217.1"
/translation="MILLAVLFLCFISSYSASVKGHTTGLSLNNDRLYKLTYSTEVLL
DRGKGKLQDSVGYRISSNVDVALLWRNPDGDDDQLIQITMKDVNVENVNQQRGEKSIF
KGKSPSKIMGKENLEALQRPTLLHLIHGKVKEFYSYQNEAVAIENIKRGLASLFQTQL
SSGTTNEVDISGNCKVTYQAHQDKVIKIKALDSCKIARSGFTTPNQVLGVSSKATSVT
TYKIEDSFVIAVLAEETHNFGLNFLQTIKGKIVSKQKLELKTTEAGPRLMSGKQAAAI
IKAVDSKYTAIPIVGQVFQSHCKGCPSLSELWRSTRKYLQPDNLSKAEAVRNFLAFIQ
HLRTAKKEEILQILKMENKEVLPQLVDAVTSAQTSDSLEAILDFLDFKSDSSIILQER
FLYACGFASHPNEELLRALISKFKGSIGSSDIRETVMIITGTLVRKLCQNEGCKLKAV
VEAKKLILGGLEKAEKKEDTRMYLLALKNALLPEGIPSLLKYAEAGEGPISHLATTAL
QRYDLPFITDEVKKTLNRIYHQNRKVHEKTVRTAAAAIILNNNPSYMDVKNILLSIGE
LPQEMNKYMLAIVQDILRFEMPASKIVRRVLKEMVAHNYDRFSRSGSSSAYTGYIERS
PRSASTYSLDILYSGSGILRRSNLNIFQYIGKAGLHGSQVVIEAQGLEALIAATPDEG
EENLDSYAGMSAILFDVQLRPVTFFNGYSDLMSKMLSASGDPISVVKGLILLIDHSQE
LQLQSGLKANIEVQGGLAIDISGAMEFSLWYRESKTRVKNRVTVVITTDITVDSSFVK
AGLETSTETEAGLEFISTVQFSQYPFLVCMQMDKDEAPFRQFEKKYERLSTGRGYVSQ
KRKESVLAGCEFPLHQENSEMCKVVFAPQPDSTSSGWF"
BASE COUNT 1026 a 699 c 730 g 875 t
ORIGIN
1 tgcagttgag gattgctggt caatatgatt cttcttgctg tgctttttct ctgcttcatt
61 tcctcatatt cagcttctgt taaaggtcac acaactggtc tctcattaaa taatgaccgg
121 ctgtacaagc tcacgtactc cactgaagtt cttcttgatc ggggcaaagg aaaactgcaa
181 gacagcgtgg gctaccgcat ttcctccaac gtggatgtgg ccttactatg gaggaatcct
241 gatggtgatg atgaccagtt gatccaaata acgatgaagg atgtaaatgt tgaaaatgtg
301 aatcagcaga gaggagagaa gagcatcttc aaaggaaaaa gcccatctaa aataatggga
361 aaggaaaact tggaagctct gcaaagacct acgctccttc atctaatcca tggaaaggtc
421 aaagagttct actcatatca aaatgaggca gtggccatag aaaatatcaa gagaggtctg
481 gctagcctat ttcagacaca gttaagctct ggaaccacca atgaggtaga tatctctgga
541 aattgtaaag tgacctacca ggctcatcaa gacaaagtga tcaaaattaa ggccttggat
601 tcatgcaaaa tagcgaggtc tggatttacg accccaaatc aggtcttggg tgtcagttca
661 aaagctacat ctgtcaccac ctataagata gaagacagct ttgttatagc tgtgcttgct
721 gaagaaacac acaattttgg actgaatttc ctacaaacca ttaaggggaa aatagtatcg
781 aagcagaaat tagagctgaa gacaaccgaa gcaggcccaa gattgatgtc tggaaagcag
841 gctgcagcca taatcaaagc agttgattca aagtacacgg ccattcccat tgtggggcag
901 gtcttccaga gccactgtaa aggatgtcct tctctctcgg agctctggcg gtccaccagg
961 aaatacctgc agcctgacaa cctttccaag gctgaggctg tcagaaactt cctggccttc
1021 attcagcacc tcaggactgc gaagaaagaa gagatccttc aaatactaaa gatggaaaat
1081 aaggaagtat tacctcagct ggtggatgct gtcacctctg ctcagacctc agactcatta
1141 gaagccattt tggacttttt ggatttcaaa agtgacagca gcattatcct ccaggagagg
1201 tttctctatg cctgtggatt tgcttctcat cccaatgaag aactcctgag agccctcatt
1261 agtaagttca aaggttctat tggtagcagt gacatcagag aaactgttat gatcatcact
1321 gggacacttg tcagaaagtt gtgtcagaat gaaggctgca aactcaaagc agtagtggaa
1381 gctaagaagt taatcctggg aggacttgaa aaagcagaga aaaaagagga caccaggatg
1441 tatctgctgg ctttgaagaa tgccctgctt ccagaaggca tcccaagtct tctgaagtat
1501 gcagaagcag gagaagggcc catcagccac ctggctacca ctgctctcca gagatatgat
1561 ctccctttca taactgatga ggtgaagaag accttaaaca gaatatacca ccaaaaccgt
1621 aaagttcatg aaaagactgt gcgcactgct gcagctgcta tcattttaaa taacaatcca
1681 tcctacatgg acgtcaagaa catcctgctg tctattgggg agcttcccca agaaatgaat
1741 aaatacatgc tcgccattgt tcaagacatc ctacgttttg aaatgcctgc aagcaaaatt
1801 gtccgtcgag ttctgaagga aatggtcgct cacaattatg accgtttctc caggagtgga
1861 tcttcttctg cctacactgg ctacatagaa cgtagtcccc gttcggcatc tacttacagc
1921 ctagacattc tctactcggg ttctggcatt ctaaggagaa gtaacctgaa catctttcag
1981 tacattggga aggctggtct tcacggtagc caggtggtta ttgaagccca aggactggaa
2041 gccttaatcg cagccacccc tgacgagggg gaggagaacc ttgactccta tgctggtatg
2101 tcagccatcc tctttgatgt tcagctcaga cctgtcacct ttttcaacgg atacagtgat
2161 ttgatgtcca aaatgctgtc agcatctggc gaccctatca gtgtggtgaa aggacttatt
2221 ctgctaatag atcattctca ggaacttcag ttacaatctg gactaaaagc caatatagag
2281 gtccagggtg gtctagctat tgatatttca ggtgcaatgg agtttagctt gtggtatcgt
2341 gagtctaaaa cccgagtgaa aaatagggtg actgtggtaa taaccactga catcacagtg
2401 gactcctctt ttgtgaaagc tggcctggaa accagtacag aaacagaagc aggcttggag
2461 tttatctcca cagtgcagtt ttctcagtac ccattcttag tttgcatgca gatggacaag
2521 gatgaagctc cattcaggca atttgagaaa aagtacgaaa ggctgtccac aggcagaggt
2581 tatgtctctc agaaaagaaa agaaagcgta ttagcaggat gtgaattccc gctccatcaa
2641 gagaactcag agatgtgcaa agtggtgttt gcccctcagc cggatagtac ttccagcgga
2701 tggttttgaa actgacctgt gatattttac ttgaatttgt ctccccgaaa gggacacaat
2761 gtggcatgac taagtacttg ctctctgaga gcacagcgtt tacatattta cctgtattta
2821 agatttttgt aaaaagctac aaaaaactgc agtttgatca aatttgggta tatgcagtat
2881 gctacccaca gcgtcatttt gaatcatcat gtgacgcttt caacaacgtt cttagtttac
2941 ttatacctct ctcaaatctc atttggtaca gtcagaatag ttattctcta agaggaaact
3001 agtgtttgtt aaaaacaaaa ataaaaacaa aaccacacaa ggagaaccca attttgtttc
3061 aacaattttt gatcaatgta tatgaagctc ttgataggac ttccttaagc atgacgggaa
3121 aaccaaacac gttccctaat caggaaaaaa aaaaaaaaaa aaaagtaaga cacaaacaaa
3181 ccattttttt ctcttttttt ggagttgggg gcccagggag aagggacaag gcttttaaaa
3241 gacttgttag ccaacttcaa gaattaatat ttatgtctct gttattgtta gttttaagcc
3301 ttaaggtaga aggcacatag aaataacatc
//