LOCUS X75308 2698 bp mRNA linear HUM 19-AUG-1994
DEFINITION H.sapiens mRNA for collagenase 3.
ACCESSION X75308
VERSION X75308.1
KEYWORDS Collagenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2698)
AUTHORS Lopez-Otin C.
JOURNAL Submitted (30-SEP-1993) to the INSDC. C. Lopez-Otin, Universidad de
Oviedo, Dept de Biologia Funcional, Area de Bioquimica, Facultad de
Medicina, C/ Julian Claveria S/N, 33006 Oviedo, SPAIN
REFERENCE 2 (bases 1 to 2698)
AUTHORS Freije J.M.P., Diez-Itza I., Balbin M., Lopez-Otin C.
TITLE Molecular cloning and expression of collagenase-3, a novel human
matrix metalloproteinase produced by breast carcinomas
JOURNAL J Biol Chem 269(24), 16766-16773(1994).
PUBMED 8207000
FEATURES Location/Qualifiers
source 1..2698
/db_xref="H-InvDB:HIT000323518"
/organism="Homo sapiens"
/isolate="patient I-9"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/sub_clone="I9-9"
/tissue_type="breast carcinoma"
/db_xref="taxon:9606"
CDS 5..1420
/product="collagenase 3"
/db_xref="GOA:P45452"
/db_xref="H-InvDB:HIT000323518.14"
/db_xref="HGNC:HGNC:7159"
/db_xref="InterPro:IPR000585"
/db_xref="InterPro:IPR001818"
/db_xref="InterPro:IPR002477"
/db_xref="InterPro:IPR006026"
/db_xref="InterPro:IPR018486"
/db_xref="InterPro:IPR018487"
/db_xref="InterPro:IPR021158"
/db_xref="InterPro:IPR021190"
/db_xref="InterPro:IPR024079"
/db_xref="InterPro:IPR028711"
/db_xref="InterPro:IPR033739"
/db_xref="InterPro:IPR036365"
/db_xref="InterPro:IPR036366"
/db_xref="InterPro:IPR036375"
/db_xref="PDB:1EUB"
/db_xref="PDB:1FLS"
/db_xref="PDB:1FM1"
/db_xref="PDB:1PEX"
/db_xref="PDB:1UC1"
/db_xref="PDB:1XUC"
/db_xref="PDB:1XUD"
/db_xref="PDB:1XUR"
/db_xref="PDB:1YOU"
/db_xref="PDB:1ZTQ"
/db_xref="PDB:2D1N"
/db_xref="PDB:2E2D"
/db_xref="PDB:2OW9"
/db_xref="PDB:2OZR"
/db_xref="PDB:2PJT"
/db_xref="PDB:2YIG"
/db_xref="PDB:3ELM"
/db_xref="PDB:3I7G"
/db_xref="PDB:3I7I"
/db_xref="PDB:3KEC"
/db_xref="PDB:3KEJ"
/db_xref="PDB:3KEK"
/db_xref="PDB:3KRY"
/db_xref="PDB:3LJZ"
/db_xref="PDB:3O2X"
/db_xref="PDB:3TVC"
/db_xref="PDB:3WV1"
/db_xref="PDB:3WV2"
/db_xref="PDB:3WV3"
/db_xref="PDB:3ZXH"
/db_xref="PDB:456C"
/db_xref="PDB:4A7B"
/db_xref="PDB:4FU4"
/db_xref="PDB:4FVL"
/db_xref="PDB:4G0D"
/db_xref="PDB:4JP4"
/db_xref="PDB:4JPA"
/db_xref="PDB:4L19"
/db_xref="PDB:5B5O"
/db_xref="PDB:5B5P"
/db_xref="PDB:5BOT"
/db_xref="PDB:5BOY"
/db_xref="PDB:5BPA"
/db_xref="PDB:5UWK"
/db_xref="PDB:5UWL"
/db_xref="PDB:5UWM"
/db_xref="PDB:5UWN"
/db_xref="PDB:830C"
/db_xref="UniProtKB/Swiss-Prot:P45452"
/protein_id="CAA53056.1"
/translation="MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLR
SYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVG
EYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGI
ADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFL
VAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPK
HPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRI
DAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTG
KTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQF
EYSIWSNRIVRVMPANSILWC"
regulatory 2669..2674
/regulatory_class="polyA_signal_sequence"
BASE COUNT 853 a 505 c 540 g 800 t
ORIGIN
1 caagatgcat ccaggggtcc tggctgcctt cctcttcttg agctggactc attgtcgggc
61 cctgcccctt cccagtggtg gtgatgaaga tgatttgtct gaggaagacc tccagtttgc
121 agagcgctac ctgagatcat actaccatcc tacaaatctc gcgggaatcc tgaaggagaa
181 tgcagcaagc tccatgactg agaggctccg agaaatgcag tctttcttcg gcttagaggt
241 gactggcaaa cttgacgata acaccttaga tgtcatgaaa aagccaagat gcggggttcc
301 tgatgtgggt gaatacaatg ttttccctcg aactcttaaa tggtccaaaa tgaatttaac
361 ctacagaatt gtgaattaca cccctgatat gactcattct gaagtcgaaa aggcattcaa
421 aaaagccttc aaagtttggt ccgatgtaac tcctctgaat tttaccagac ttcacgatgg
481 cattgctgac atcatgatct cttttggaat taaggagcat ggcgacttct acccatttga
541 tgggccctct ggcctgctgg ctcatgcttt tcctcctggg ccaaattatg gaggagatgc
601 ccattttgat gatgatgaaa cctggacaag tagttccaaa ggctacaact tgtttcttgt
661 tgctgcgcat gagttcggcc actccttagg tcttgaccac tccaaggacc ctggagcact
721 catgtttcct atctacacct acaccggcaa aagccacttt atgcttcctg atgacgatgt
781 acaagggatc cagtctctct atggtccagg agatgaagac cccaacccta aacatccaaa
841 aacgccagac aaatgtgacc cttccttatc ccttgatgcc attaccagtc tccgaggaga
901 aacaatgatc tttaaagaca gattcttctg gcgcctgcat cctcagcagg ttgatgcgga
961 gctgttttta acgaaatcat tttggccaga acttcccaac cgtattgatg ctgcatatga
1021 gcacccttct catgacctca tcttcatctt cagaggtaga aaattttggg ctcttaatgg
1081 ttatgacatt ctggaaggtt atcccaaaaa aatatctgaa ctgggtcttc caaaagaagt
1141 taagaagata agtgcagctg ttcactttga ggatacaggc aagactctcc tgttctcagg
1201 aaaccaggtc tggagatatg atgatactaa ccatattatg gataaagact atccgagact
1261 aatagaagaa gacttcccag gaattggtga taaagtagat gctgtctatg agaaaaatgg
1321 ttatatctat tttttcaacg gacccataca gtttgaatac agcatctgga gtaaccgtat
1381 tgttcgcgtc atgccagcaa attccatttt gtggtgttaa gtgtcttttt aaaaattgtt
1441 atttaaatcc tgaagagcat ttggggtaat acttccagaa gtgcggggta ggggaagaag
1501 agctatcagg agaaagcttg gttctgtgaa caagcttcag taagttatct ttgaatatgt
1561 agtatctata tgactatgcg tggctggaac cacattgaag aatgttagag taatgaaatg
1621 gaggatctct aaagagcatc tgattcttgt tgctgtacaa aagcaatggt tgatgatact
1681 tcccacacca caaatgggac acatggtctg tcaatgagag cataatttaa aaatatattt
1741 ataaggaaat tttacaaggg cataaagtaa atacatgcat ataatgaata aatcattctt
1801 actaaaaagt ataaaatagt atgaaaatgg aaatttggga gagccataca taaaagaaat
1861 aaaccaaagg aaaatgtctg taataataga ctgtaacttc caaataaata attttcattt
1921 tgcactgagg atattcagat gtatgtgccc ttcttcacac agacactaac gaaatatcaa
1981 agtcattaaa gacaggagac aaaagagcag tggtaagaat agtagatgtg gcctttgaat
2041 tctgtttaat tttcactttt ggcaatgact caaagtctgc tctcatataa gacaaatatt
2101 cctttgcata ttataaagga taaagaagga tgatgtcttt ttattaaaat atttcaggtt
2161 cttcagaagt cacacattac aaagttaaaa ttgttatcaa aatagtctaa ggccatggca
2221 tccctttttc ataaattatt tgattattta agactaaaag ttgcatttta accctatttt
2281 acctagctaa ttatttaatt gtccggtttg tcttggatat ataggctatt ttctaaagac
2341 ttgtatagca tgaaataaaa tatatcttat aaagtggaag tatgtatatt aaaaaagaga
2401 catccaaatt tttttttaaa gcagtctact agattgtgat cccttgagat atggaaggat
2461 gccttttttt ctctgcattt aaaaaaatcc cccagcactt cccacagtgc ctattgatac
2521 ttggggaggg tgcttggcac ttattgaata tatgatcggc catcaaggga agaactattg
2581 tgctcagaga cactgttgat aaaaactcag gcaaagaaaa tgaaatgcat atttgcaaag
2641 tgtattagga agtgtttatg ttgtttataa taaaaatata ttttcaacag aaaaaaaa
//