LOCUS       X73870                   318 bp    mRNA    linear   HUM 30-MAR-1995
DEFINITION  H.sapiens mRNA for Ig kappa light chain variable region
            (V-J),subgroup I (clone D7).
ACCESSION   X73870
VERSION     X73870.1
KEYWORDS    autoantibody; Ig J-segment; Ig kappa light chain; Ig subgroup I; Ig
            variable region; immunoglobulin.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Hexham J.M., Partridge L.J., Furmaniak J., Petersen V.B.,
            Colls J.C., Pegg C.A.S., Rees-Smith B., Burton D.R.
  TITLE     Probing the human anti-thyroid peroxidase repertoire of a
            Hashimoto's thyroiditis patient using combinatorial phage display
            libraries
  JOURNAL   Unpublished.
REFERENCE   2  (bases 1 to 318)
  AUTHORS   Hexham J.
  JOURNAL   Submitted (25-JUN-1993) to the INSDC. J. Hexham, Univ. of
            Sheffield, Dept. of Mol. Biology and Biotechnology, P. O. Box 594,
            Firth Court, Western Bank, Sheffield S10 2UH, UK
REFERENCE   3  (bases 1 to 318)
  AUTHORS   Hexham J.M., Furmaniak J., Pegg C., Burton D.R., Rees-Smith B.
  TITLE     Cloning of a human autoimmune response: preparation and sequencing
            of a human anti-thyroglobulin autoantibody using a combinatorial
            approach
  JOURNAL   Autoimmunity 12(2), 135-141(1992).
   PUBMED   1617110
REFERENCE   4  (bases 1 to 318)
  AUTHORS   Hexham J.M., Partridge L.J., Furmaniak J., Petersen V.B.,
            Colls J.C., Pegg C., Rees Smith B., Burton D.R.
  TITLE     Cloning and characterisation of TPO autoantibodies using
            combinatorial phage display libraries
  JOURNAL   Autoimmunity 17(3), 167-179(1994).
   PUBMED   7524700
FEATURES             Location/Qualifiers
     source          1..318
                     /db_xref="H-InvDB:HIT000323400"
                     /organism="Homo sapiens"
                     /isolate="Hashimoto patient"
                     /mol_type="mRNA"
                     /sex="female"
                     /clone_lib="lambda phage"
                     /clone="D7"
                     /cell_type="thyroid lymphocyte"
                     /note="rearranged"
                     /db_xref="taxon:9606"
     V_region        1..318
                     /product="Ig kappa light chain variable region, subgroup
                     I"
BASE COUNT           86 a           77 c           80 g           75 t
ORIGIN      
        1 gagctcaccc agtctccatc ctccctgtct gcatctgtag gagacagagt caccatcact
       61 tgccaggcga gtcaggacat taggaactat ttaagttggt atcagcagaa accagggaaa
      121 gcccctaagc tcctgatcca cgatgcatcg aatttggaaa caggggtccc atcaaggttc
      181 agtggaagtg gatctgggac agattttact ttctccatca ggagcctgca gcctgaggat
      241 attgcaacat atttctgtca acagtatgat agtctggtca ctttcggcgg agggaccaag
      301 gtggagatca aacgaact
//