LOCUS       X73868                   336 bp    mRNA    linear   HUM 30-MAR-1995
DEFINITION  H.sapiens mRNA for Ig kappa light chain variable region (V-J),
            subgroup IV (clone D3).
ACCESSION   X73868
VERSION     X73868.1
KEYWORDS    autoantibody; Ig J-segment; Ig kappa light chain; Ig subgroup IV;
            Ig variable region; immunoglobulin.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 336)
  AUTHORS   Hexham J.M., Partridge L.J., Furmaniak J., Petersen V.B.,
            Colls J.C., Pegg C.A.S., Rees-Smith B., Burton D.R.
  TITLE     Probing the human anti-thyroid peroxidase repertoire of a
            Hashimoto's thyroiditis patient using combinatorial phage display
            libraries
  JOURNAL   Unpublished.
REFERENCE   2  (bases 1 to 336)
  AUTHORS   Hexham J.
  JOURNAL   Submitted (25-JUN-1993) to the INSDC. J. Hexham, Univ. of
            Sheffield, Dept. of Mol. Biology and Biotechnology, P. O. Box 594,
            Firth Court, Western Bank, Sheffield S10 2UH, UK
REFERENCE   3  (bases 1 to 336)
  AUTHORS   Hexham J.M., Furmaniak J., Pegg C., Burton D.R., Rees-Smith B.
  TITLE     Cloning of a human autoimmune response: preparation and sequencing
            of a human anti-thyroglobulin autoantibody using a combinatorial
            approach
  JOURNAL   Autoimmunity 12(2), 135-141(1992).
   PUBMED   1617110
REFERENCE   4  (bases 1 to 336)
  AUTHORS   Hexham J.M., Partridge L.J., Furmaniak J., Petersen V.B.,
            Colls J.C., Pegg C., Rees Smith B., Burton D.R.
  TITLE     Cloning and characterisation of TPO autoantibodies using
            combinatorial phage display libraries
  JOURNAL   Autoimmunity 17(3), 167-179(1994).
   PUBMED   7524700
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Homo sapiens"
                     /isolate="Hashimoto patient"
                     /mol_type="mRNA"
                     /sex="female"
                     /clone_lib="lambda phage"
                     /clone="D3"
                     /cell_type="thyroid lymphocyte"
                     /note="rearranged"
                     /db_xref="taxon:9606"
     V_region        1..336
                     /product="Ig kappa light chain variable region, subgroup
                     IV"
BASE COUNT           78 a           98 c           86 g           74 t
ORIGIN      
        1 gagctcaccc agtctccaga ctccctggct gtgtctctgg gcgagagggc caccatcaac
       61 tgcagtccca gccagagtgt tttatacagc tccaacaaga actacctagc ttggtaccag
      121 cagaaaccag gacagcctcc taagctgctc atttactggg catcttcacg ggaatccggg
      181 gtccctgacc gattcagtgg cagcgggtct gggacagatt tcgctctcac catcagcggc
      241 ctgcaggctg aggatgtggc aggttattac tgtcaacaat attatagtcc tcctctcact
      301 ttcgccggag ggaccaaggt ggagatcaaa cgaact
//