LOCUS       X73866                   327 bp    mRNA    linear   HUM 30-MAR-1995
DEFINITION  H.sapiens mRNA for Ig kappa light chain variable region
            (V-J),subgroup III (clone C9).
ACCESSION   X73866
VERSION     X73866.1
KEYWORDS    autoantibody; Ig J-segment; Ig kappa light chain; Ig subgroup III;
            Ig variable region; immunoglobulin.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Hexham J.M., Partridge L.J., Furmaniak J., Petersen V.B.,
            Colls J.C., Pegg C.A.S., Rees-Smith B., Burton D.R.
  TITLE     Probing the human anti-thyroid peroxidase repertoire of a
            Hashimoto's thyroiditis patient using combinatorial phage display
            libraries
  JOURNAL   Unpublished.
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Hexham J.
  JOURNAL   Submitted (25-JUN-1993) to the INSDC. J. Hexham, Univ. of
            Sheffield, Dept. of Mol. Biology and Biotechnology, P. O. Box 594,
            Firth Court, Western Bank, Sheffield S10 2UH, UK
REFERENCE   3  (bases 1 to 327)
  AUTHORS   Hexham J.M., Furmaniak J., Pegg C., Burton D.R., Rees-Smith B.
  TITLE     Cloning of a human autoimmune response: preparation and sequencing
            of a human anti-thyroglobulin autoantibody using a combinatorial
            approach
  JOURNAL   Autoimmunity 12(2), 135-141(1992).
   PUBMED   1617110
REFERENCE   4  (bases 1 to 327)
  AUTHORS   Hexham J.M., Partridge L.J., Furmaniak J., Petersen V.B.,
            Colls J.C., Pegg C., Rees Smith B., Burton D.R.
  TITLE     Cloning and characterisation of TPO autoantibodies using
            combinatorial phage display libraries
  JOURNAL   Autoimmunity 17(3), 167-179(1994).
   PUBMED   7524700
FEATURES             Location/Qualifiers
     source          1..327
                     /db_xref="H-InvDB:HIT000323396"
                     /organism="Homo sapiens"
                     /isolate="Hashimoto patient"
                     /mol_type="mRNA"
                     /sex="female"
                     /clone_lib="lambda phage"
                     /clone="C9"
                     /cell_type="thyroid lymphocyte"
                     /note="rearranged"
                     /db_xref="taxon:9606"
     V_region        1..327
                     /product="Ig kappa light chain variable region, subgroup
                     III"
BASE COUNT           74 a           95 c           86 g           72 t
ORIGIN      
        1 gagctcacgc agtctccagg caccctgtct ttgtctccag gggaaagagc caccctctcc
       61 tgcagggcca gtcagagtgt tagcagcaac ttctttgcct ggtaccagca gaaacctggc
      121 caggctccca ggctcctcat ctatggtgca tccagcagga tcactggcat ccctgacagg
      181 ttcagtggca gtgggtctgg aacagacttc actctcacca tcagcagact ggagcctgaa
      241 gattttgcag tgtattactg tcagcagtat ggtagctcaa ctccgctcac tttcggcgga
      301 gggaccaagg tggagatcaa acgaact
//