LOCUS X73478 2661 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens hPTPA mRNA.
ACCESSION X73478
VERSION X73478.1
KEYWORDS phosphotyrosyl phosphatase activator.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Cayla X., Van Hoof C., Bosch M., Waelkens E., Peeters B.,
Merlevede W., Goris J.
TITLE Molecular cloning, expression, and characterization of PTPA, a
protein that activates the tyrosyl phosphatase activity of protein
phosphatase 2A
JOURNAL J Biol Chem 269(22), 15668-15675(1994).
PUBMED 8195217
REFERENCE 2 (bases 1 to 2661)
AUTHORS Goris J.
JOURNAL Submitted (21-JUN-1993) to the INSDC. J. Goris, Katholieke
Universiteit Leuven, Faculteit der Geneeskunde, Campus Gasthuisberg
Herestraat, B-3000 Leuven, BELGIUM
FEATURES Location/Qualifiers
source 1..2661
/db_xref="H-InvDB:HIT000323373"
/organism="Homo sapiens"
/mol_type="mRNA"
/dev_stage="adult"
/clone="H6"
/tissue_type="heart"
/db_xref="taxon:9606"
CDS 190..1161
/gene="PTPA"
/product="phosphotyrosyl phosphatase activator"
/db_xref="GOA:Q15257"
/db_xref="H-InvDB:HIT000323373.13"
/db_xref="HGNC:HGNC:9308"
/db_xref="InterPro:IPR004327"
/db_xref="InterPro:IPR037218"
/db_xref="PDB:2G62"
/db_xref="PDB:2HV6"
/db_xref="PDB:2HV7"
/db_xref="PDB:2IXM"
/db_xref="PDB:4LAC"
/db_xref="PDB:4NY3"
/db_xref="UniProtKB/Swiss-Prot:Q15257"
/protein_id="CAA51873.1"
/translation="MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQA
YADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLLALLNTLDRWIDETPPVDQPSRFGN
KAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFA
AFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFL
PFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLW
NISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG"
regulatory 2613..2618
/gene="PTPA"
/regulatory_class="polyA_signal_sequence"
polyA_site 2638
/gene="PTPA"
BASE COUNT 509 a 764 c 789 g 599 t
ORIGIN
1 ccggcaccga catggcggcc gtcttcgctg tggtgacttt aactctcggt tttcggttct
61 agccggccgg cgctcacttg tcttcaggaa gctcggagcc tttggtggag ccggggagag
121 gaagggtggg tgcaagagtg aaaggcgaga ggggactgca agcatccggg tcgctgctgg
181 ccggagcaga tggctgaggg cgagcggcag ccgccgccag attcttcaga ggaggcccct
241 ccagccactc agaacttcat cattccaaaa aaggagatcc acacagttcc agacatgggc
301 aaatggaagc gttctcaggc atacgctgac tacatcggat tcatccttac cctcaacgaa
361 ggtgtgaagg ggaagaagct gaccttcgag tacagagtct ccgaggccat tgagaaacta
421 ctcgctcttc tcaacacgct ggacaggtgg attgatgaga ctcctccagt ggaccagccc
481 tctcggtttg ggaataaggc atacaggacc tggtatgcca aacttgatga ggaagcagaa
541 aacttggtgg ccacagtggt ccctacccat ctggcagctg ctgtgcctga ggtggctgtt
601 tacctaaagg agtcagtggg gaactccacg cgcattgact acggcacagg gcatgaggca
661 gccttcgctg ctttcctctg ctgtctctgc aagattgggg tgctccgggt ggatgaccaa
721 atagctattg tcttcaaggt gttcaatcgg taccttgagg ttatgcggaa actccagaaa
781 acatacagga tggagccagc cggcagccag ggagtgtggg gtctggatga cttccagttt
841 ctgcccttca tctggggcag ttcgcagctg atagaccacc catacctgga gcccagacac
901 tttgtggatg agaaggccgt gaatgagaac cacaaggact acatgttcct ggagtgtatc
961 ctgtttatta ccgagatgaa gactggccca tttgcagagc actccaacca gctgtggaac
1021 atcagcgccg tgccttcctg gtccaaagtg aaccagggtc tcatccgcat gtataaggcc
1081 gagtgcctgg agaagttccc tgtgatccag cacttcaagt tcgggagcct gctgcccatc
1141 catcctgtca cgtcgggcta ggagggccaa gccgaagagc cacccaggcc acagttcctg
1201 tgcctgcctt ccccacccca gcagtggccc ctcccccatc ccctccctct gttcgtcccg
1261 tttgatgaga ggctgtttac tggggtgggg tggcgagatg ggcttgaggg ggctcagagc
1321 ataaggcttc agggcccaag ttgggagaag tgaccaaagt gtagccagtt ttctgagttc
1381 ccgtgtgcta gactggccag aagagagggt ctggggcctg gtcactcggc cactctctcc
1441 tgtttctggc ctcttctccc ttcactcccg gtccagtctg gttttgagag caggggctgt
1501 tctgcagcac ctcagggaag ggaggagaga tacctgctgc ttccattgct tttcccttcc
1561 tggagtcgat gcctttctaa gggttggagc tgctccttgc aggggcgggt cagtttccca
1621 ggccatgccg gggtggccat ctatgctagg gctggaagct gagctggccg ccagctgtgg
1681 gctggggtgg ggtgggtggg gtcgggtggt ggagaggcct tagctgtcct gctggtgccc
1741 ctcccaggct ccttttcacc ctgccccctg cctgaggccc cctgtgtcca agcctccccc
1801 tggctcttca gttctctagc ccttggcttt gctgggtttc ctgactgtag ccacatctct
1861 cccgctccct aagggtaacc tagccaatgg aagctggcct ttgggtaggt gctgggctcc
1921 tgggagggcc cagatgatgg gtgaggcatg tctttccaga actttcctgg cagggagggg
1981 atggcagaaa ctcagggagg cttggggccc attgtatctg gagagcctgg attcctcttg
2041 gcagtcttag cccagccact tctgctacct ttgcgctgct gtgagcctca ccctgcccct
2101 gggccctgct tctctgctcc cctgggtgat gggtgggccc agaaggtggc agtcccacac
2161 cttgtcctcc cacctccctg aactgtccat tgcttttata gggtgaggta agtgacagcc
2221 tcccaagccc aggctttggc actcagaatg ggcccagtgg gggctgggca gcccattgag
2281 ggccaccgcc gaggcgcgag gtttctccta gggctgttcc tgggcctggc tcttacaggc
2341 ttggtcagga gggctggcct tcttcactgc cccctcctgt gtctgggtcc acacaccctt
2401 cagtaaccaa cggcactgag aagcacagca caggggctca gcctgggatc cggtgatggt
2461 ctgggcagag gctgggtcag gagtcccaaa ggtcagtgac agtttctcag aagaggccca
2521 gcgtccacct ctctcccagg gccagacacc ccttcctggc tcccccatcc ccctatggct
2581 cccagcccct tgcaccctca ttgctgttca gattaaagcc tctgttttgc acctgtcaaa
2641 aaaaaaaaaa aaaaaaaaaa a
//