LOCUS X72889 5959 bp mRNA linear HUM 21-OCT-2008
DEFINITION H.sapiens hbrm mRNA.
ACCESSION X72889
VERSION X72889.1
KEYWORDS glucocorticoid receptor; hbrm gene; helicase; nuclear;
transcriptional regulator.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5959)
AUTHORS Muchardt C., Yaniv M.
TITLE A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and
Drosophila brm genes potentiates transcriptional activation by the
glucocorticoid receptor
JOURNAL EMBO J. 12(11), 4279-4290(1993).
PUBMED 8223438
REFERENCE 2 (bases 1 to 5959)
AUTHORS Muchardt C.
JOURNAL Submitted (25-MAR-1993) to the INSDC. C. Muchardt, Pasteur
Institute Paris, Unite de Virus Oncogenes, 25 rue du Docteur Roux,
75724 Paris Cedex 15, FRANCE
REFERENCE 3 (bases 1 to 5959)
AUTHORS Aves S.J., Hindley J., Phear G.A., Tongue N.
TITLE A fission yeast gene mapping close to suc1 encodes a protein
containing two bromodomains
JOURNAL Mol. Gen. Genet. 248(4), 491-498(1995).
PUBMED 7565614
FEATURES Location/Qualifiers
source 1..5959
/db_xref="H-InvDB:HIT000323354"
/organism="Homo sapiens"
/map="5 F"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="lambda gt10"
/tissue_type="liver"
/db_xref="taxon:9606"
CDS 223..4983
/gene="hbrm"
/product="HBRM"
/db_xref="GOA:P51531"
/db_xref="H-InvDB:HIT000323354.15"
/db_xref="HGNC:HGNC:11098"
/db_xref="InterPro:IPR000330"
/db_xref="InterPro:IPR001487"
/db_xref="InterPro:IPR001650"
/db_xref="InterPro:IPR006576"
/db_xref="InterPro:IPR014001"
/db_xref="InterPro:IPR014012"
/db_xref="InterPro:IPR014978"
/db_xref="InterPro:IPR018359"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR029295"
/db_xref="InterPro:IPR030088"
/db_xref="InterPro:IPR036427"
/db_xref="InterPro:IPR037259"
/db_xref="InterPro:IPR038718"
/db_xref="PDB:2DAT"
/db_xref="PDB:4QY4"
/db_xref="PDB:5DKC"
/db_xref="PDB:5DKH"
/db_xref="PDB:6EG2"
/db_xref="PDB:6EG3"
/db_xref="PDB:6HAX"
/db_xref="PDB:6HAY"
/db_xref="PDB:6HAZ"
/db_xref="UniProtKB/Swiss-Prot:P51531"
/protein_id="CAA51407.1"
/translation="MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMM
GPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP
HPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGD
PQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQ
QQQQQQQQQQQQQQQQQQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPV
PAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLD
PVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEV
VACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNS
ILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEE
GYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENA
EGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYE
VAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVD
DEYSMQYSARGSQSYYTVAHAISEWVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLN
GILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKI
SYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHH
CKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFA
MTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKI
LYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLG
YSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFL
YLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNP
HQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKS
SSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDAR
NPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQ
WLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPK
LTKQMNAIIDTCINYKDSCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYY
ELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSV
FKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKK
RPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE"
BASE COUNT 1822 a 1352 c 1504 g 1281 t
ORIGIN
1 gaattccgga tgctcagatg aaagccccga gatcacagag acccggcgag atcacagaga
61 cccggcctga aggaacgtgg aaagaccaat gtacctgttt tgaccggttg cctggagcaa
121 gaagttccag ttggggagaa ttttcagaag ataaagtcgg agattgtgga aagacttgac
181 ttgcagcatt actctactga ctggcagaga caggagaggt agatgtcaac gcccacagac
241 cctggtgcga tgccccaccc agggccttcg ccgggtcctg ggccttcccc tgggccaatt
301 cttgggccta gtccaggacc aggaccatcc ccaggttccg tccacagcat gatggggcca
361 agtcctggac ctccaagtgt ctcccatcct atgccgacga tggggtccac agacttccca
421 caggaaggca tgcatcaaat gcataagccc atcgatggta tacatgacaa ggggattgta
481 gaagacatcc attgtggatc catgaagggc actggtatgc gaccacctca cccaggcatg
541 ggccctcccc agagtccaat ggatcaacac agccaaggtt atatgtcacc acacccatct
601 ccattaggag ccccagagca cgtctccagc cctatgtctg gaggaggccc aactccacct
661 cagatgccac caagccagcc gggggccctc atcccaggtg atccgcaggc catgagccag
721 cccaacagag gtccctcacc tttcagtcct gtccagctgc atcagcttcg agctcagatt
781 ttagcttata aaatgctggc ccgaggccag cccctccccg aaacgctgca gcttgcagtc
841 caggggaaaa ggacgttgcc tggcttgcag caacaacagc agcagcaaca gcagcagcag
901 cagcagcagc agcagcagca gcagcagcaa cagcagccgc cgcaaccaca gacgcagcaa
961 caacagcagc cggcccttgt taactacaac agaccatctg gcccggggcc ggagctgagc
1021 ggcccgagca ccccgcagaa gctgccggtg cccgcgcccg gcggccggcc ctcgcccgcg
1081 ccccccgcag ccgcgcagcc gcccgcggcc gcagtgcccg ggccctcagt gccgcagccg
1141 gccccggggc agccctcgcc cgtcctccag ctgcagcaga agcagagccg catcagcccc
1201 atccagaaac cgcaaggcct ggaccccgtg gaaattctgc aagagcggga atacagactt
1261 caggcccgca tagctcatag gatacaagaa ctggaaaatc tgcctggctc tttgccacca
1321 gatttaagaa ccaaagcaac cgtggaacta aaagcacttc ggttactcaa tttccagcgt
1381 cagctgagac aggaggtggt ggcctgcatg cgcagggaca cgaccctgga gacggctctc
1441 aactccaaag catacaaacg gagcaagcgc cagactctga gagaagctcg catgaccgag
1501 aagctggaga agcagcagaa gattgagcag gagaggaaac gccgtcagaa acaccaggaa
1561 tacctgaaca gtattttgca acatgcaaaa gattttaagg aatatcatcg gtctgtggcc
1621 ggaaagatcc agaagctctc caaagcagtt gcaacttggc atgccaacac tgaaagagag
1681 cagaagaagg agacagagcg gattgaaaag gagagaatgc ggcgactgat ggctgaagat
1741 gaggagggtt atagaaaact gattgatcaa aagaaagaca ggcgtttagc ttaccttttg
1801 cagcagaccg atgagtatgt agccaatctg accaatctgg tttgggagca caagcaagcc
1861 caggcagcca aagagaagaa gaagaggagg aggaggaaga agaaggctga ggagaatgca
1921 gagggtgggg agtctgccct gggaccggat ggagagccca tagatgagag cagccagatg
1981 agtgacctcc ctgtcaaagt gactcacaca gaaaccggca aggttctgtt cggaccagaa
2041 gcacccaaag caagtcagct ggacgcctgg ctggaaatga atcctggtta tgaagttgcc
2101 cctagatctg acagtgaaga gagtgattct gattatgagg aagaggatga ggaagaagag
2161 tccagtaggc aggaaaccga agagaaaata ctcctggatc caaatagcga agaagtttct
2221 gagaaggatg ctaagcagat cattgagaca gctaagcaag acgtggatga tgaatacagc
2281 atgcagtaca gtgccagggg ctcccagtcc tactacaccg tggctcatgc catctcggag
2341 tgggtggaga aacagtctgc cctcctaatt aatgggaccc taaagcatta ccagctccag
2401 ggcctggaat ggatggtttc cctgtataat aacaacttga acggaatctt agccgatgaa
2461 atggggcttg gaaagaccat acagaccatt gcactcatca cttatctgat ggagcacaaa
2521 agactcaatg gcccctatct catcattgtt cccctttcga ctctatctaa ctggacatat
2581 gaatttgaca aatgggctcc ttctgtggtg aagatttctt acaagggtac tcctgccatg
2641 cgtcgctccc ttgtccccca gctacggagt ggcaaattca atgtcctctt gactacttat
2701 gagtatatta taaaagacaa gcacattctt gcaaagattc ggtggaaata catgatagtg
2761 gacgaaggcc accgaatgaa gaatcaccac tgcaagctga ctcaggtctt gaacactcac
2821 tatgtggccc ccagaaggat cctcttgact gggaccccgc tgcagaataa gctccctgaa
2881 ctctgggccc tcctcaactt cctcctccca acaattttta agagctgcag cacatttgaa
2941 caatggttca atgctccatt tgccatgact ggtgaaaggg tggacttaaa tgaagaagaa
3001 actatattga tcatcaggcg tctacataag gtgttaagac catttttact aaggagactg
3061 aagaaagaag ttgaatccca gcttcccgaa aaagtggaat atgtgatcaa gtgtgacatg
3121 tcagctctgc agaagattct gtatcgccat atgcaagcca aggggatcct tctcacagat
3181 ggttctgaga aagataagaa ggggaaagga ggtgctaaga cacttatgaa cactattatg
3241 cagttgagaa aaatctgcaa ccacccatat atgtttcagc acattgagga atcctttgct
3301 gaacacctag gctattcaaa tggggtcatc aatggggctg aactgtatcg ggcctcaggg
3361 aagtttgagc tgcttgatcg tattctgcca aaattgagag cgactaatca ccgagtgctg
3421 cttttctgcc agatgacatc tctcatgacc atcatggagg attattttgc ttttcggaac
3481 ttcctttacc tacgccttga tggcaccacc aagtctgaag atcgtgctgc tttgctgaag
3541 aaattcaatg aacctggatc ccagtatttc attttcttgc tgagcacaag agctggtggc
3601 ctgggcttaa atcttcaggc agctgataca gtggtcatct ttgacagcga ctggaatcct
3661 catcaggatc tgcaggccca agaccgagct caccgcatcg ggcagcagaa cgaggtccgg
3721 gtactgaggc tctgtaccgt gaacagcgtg gaggaaaaga tcctcgcggc cgcaaaatac
3781 aagctgaacg tggatcagaa agtgatccag gcgggcatgt ttgaccaaaa gtcttcaagc
3841 cacgagcgga gggcattcct gcaggccatc ttggagcatg aagaggaaaa tgaggaagaa
3901 gatgaagtac cggacgatga gactctgaac caaatgattg ctcgacgaga agaagaattt
3961 gaccttttta tgcggatgga catggaccgg cggagggaag atgcccggaa cccgaaacgg
4021 aagccccgtt taatggagga ggatgagctg ccctcctgga tcattaagga tgacgctgaa
4081 gtagaaaggc tcacctgtga agaagaggag gagaaaatat ttgggagggg gtcccgccag
4141 cgccgtgacg tggactacag tgacgccctc acggagaagc agtggctaag ggccatcgaa
4201 gacggcaatt tggaggaaat ggaagaggaa gtacggctta agaagcgaaa aagacgaaga
4261 aatgtggata aagatcctgc aaaagaagat gtggaaaaag ctaagaagag aagaggccgc
4321 cctcccgctg agaaactgtc accaaatccc cccaaactga caaagcagat gaacgctatc
4381 atcgatacgt gtataaacta caaagatagt tgtaacgtgg agaaggtgcc cagtaattct
4441 cagttggaaa tagaaggaaa cagttcaggg cgacagctca gtgaagtctt cattcagtta
4501 ccttcaagga aagaattacc agaatactat gaattaatta ggaagccagt ggatttcaaa
4561 aaaataaagg aaaggattcg taatcataag taccggagcc taggcgacct ggagaaggat
4621 gtcatgcttc tctgtcacaa cgctcagacg ttcaacctgg agggatccca gatctatgaa
4681 gactccatcg tcttacagtc agtgtttaag agtgcccggc agaaaattgc caaagaggaa
4741 gagagtgagg atgaaagcaa tgaagaggag gaagaggaag atgaagaaga gtcagagtcc
4801 gaggcaaaat cagtcaaggt gaaaattaag ctcaataaaa aagatgacaa aggccgggac
4861 aaagggaaag gcaagaaaag gccaaatcga ggaaaagcca aacctgtagt gagcgatttt
4921 gacagcgatg aggagcagga tgaacgtgaa cagtcagaag gaagtgggac ggatgatgag
4981 tgatcagtat ggaccttttt ccttggtaga actgaattcc ttcctcccct gtctcatttc
5041 tacccagtga gttcatttgt catataggca ctgggttgtt tctatatcat catcgtctat
5101 aaactagctt taggatagtg ccagacaaac atatgatatc atggtgtaaa aaacacacac
5161 atacacaaat atttgtaaca tattgtgacc aaatgggcct caaagattca gattgaaaca
5221 aacaaaaagc ttttgatgga aaatatgtgg gtggatagta tatttctatg ggtgggtcta
5281 atttggtaac ggtttgattg tgcctggttt tatcacctgt tcagatgaga agatttttgt
5341 cttttgtagc actgataacc aggagaagcc attaaaagcc actggttatt ttatttttca
5401 tcaggcaatt ttcgaggttt ttatttgttc ggtattgttt ttttacactg tggtacatat
5461 aagcaacttt aataggtgat aaatgtacag tagttagatt tcacctgcat atacgttttt
5521 ccattttatg ctctatgatc tgaacaaaag ctttttgaat tgtataagat ttatgtctac
5581 tgtaaacatt gcttaatttt tttgctcttg atttaaaaaa aagttttgtt gaaagcgcta
5641 ttgaatattg caatctatat agtgtattgg atggcttctt ttgtcaccct gatctcctat
5701 gttaccaatg tgtatcgtct ccttctccct aaagtgtact taatctttgc tttctttgca
5761 caatgtcttt ggttgcaagt cataagcctg aggcaaataa attccagtaa tttcgaagaa
5821 tgtggtgttg gtgctttcct aataaagaaa taatttcgct tgaaaaaaaa aaaaaaaaaa
5881 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
5941 aaaaaaaaaa aaggaattc
//