LOCUS X72012 3073 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens end mRNA for endoglin.
ACCESSION X72012
VERSION X72012.1
KEYWORDS END gene; endoglin; TGF beta binding protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Bellon T., Corbi A., Lastres P., Cales C., Cebrian M., Vera S.,
Cheifetz S., Massague J., Letarte M., Bernabeu C.
TITLE Identification and expression of two forms of the human
transforming growth factor-beta-binding protein endoglin with
distinct cytoplasmic regions
JOURNAL Eur. J. Immunol. 23(9), 2340-2345(1993).
PUBMED 8370410
REFERENCE 2 (bases 1 to 3073)
AUTHORS Bernabeu C.
JOURNAL Submitted (19-MAY-1993) to the INSDC. C. Bernabeu, Centro de
Investigaciones Biologicas, C.S.I.C., Velazquez, 144, 28006 Madrid,
SPAIN
REFERENCE 3
AUTHORS Bellon T.
JOURNAL Thesis (1993), Universidad Autonoma, Madrid, SPAIN
COMMENT Related sequence: J05481
FEATURES Location/Qualifiers
source 1..3073
/db_xref="H-InvDB:HIT000323176"
/organism="Homo sapiens"
/chromosome="9q34qter"
/mol_type="mRNA"
/clone_lib="lambda gt10"
/clone="3.3"
/cell_line="HL-60"
/db_xref="taxon:9606"
sig_peptide 282..356
CDS 282..2159
/gene="END"
/product="endoglin"
/db_xref="GOA:P17813"
/db_xref="H-InvDB:HIT000323176.14"
/db_xref="HGNC:HGNC:3349"
/db_xref="InterPro:IPR001507"
/db_xref="PDB:5HZV"
/db_xref="PDB:5HZW"
/db_xref="PDB:5I04"
/db_xref="UniProtKB/Swiss-Prot:P17813"
/protein_id="CAA50891.1"
/translation="MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTY
TTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVN
SSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAA
ELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEA
HILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGE
YSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRL
QTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDP
SCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSF
QLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQ
GRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHR
TVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTREYPRPP
Q"
BASE COUNT 607 a 1094 c 841 g 531 t
ORIGIN
1 cctggggcca ggactgctgc tgtcactgcc atccattgga gcccagcacc ccctccccgc
61 ccatccttcg gacagcaact ccagcccagc cccgcgtccc tgtgtccact tctcctgacc
121 cctcggccgc caccccagaa ggctggagca gggacgccgt cgctccggcc gcctgctccc
181 ctcgggtccc cgtgcgagcc cacgccggcc ccggtgcccg cccgcagccc tgccactgga
241 cacaggataa ggcccagcgc acaggccccc acgtggacag catggaccgc ggcacgctcc
301 ctctggctgt tgccctgctg ctggccagct gcagcctcag ccccacaagt cttgcagaaa
361 cagtccattg tgaccttcag cctgtgggcc ccgagagggg cgaggtgaca tataccacta
421 gccaggtctc gaagggctgc gtggctcagg cccccaatgc catccttgaa gtccatgtcc
481 tcttcctgga gttcccaacg ggcccgtcac agctggagct gactctccag gcatccaagc
541 aaaatggcac ctggccccga gaggtgcttc tggtcctcag tgtaaacagc agtgtcttcc
601 tgcatctcca ggccctggga atcccactgc acttggccta caattccagc ctggtcacct
661 tccaagagcc cccgggggtc aacaccacag agctgccatc cttccccaag acccagatcc
721 ttgagtgggc agctgagagg ggccccatca cctctgctgc tgagctgaat gacccccaga
781 gcatcctcct ccgactgggc caagcccagg ggtcactgtc cttctgcatg ctggaagcca
841 gccaggacat gggccgcacg ctcgagtggc ggccgcgtac tccagccttg gtccggggct
901 gccacttgga aggcgtggcc ggccacaagg aggcgcacat cctgagggtc ctgccgggcc
961 actcggccgg gccccggacg gtgacggtga aggtggaact gagctgcgca cccggggatc
1021 tcgatgccgt cctcatcctg cagggtcccc cctacgtgtc ctggctcatc gacgccaacc
1081 acaacatgca gatctggacc actggagaat actccttcaa gatctttcca gagaaaaaca
1141 ttcgtggctt caagctccca gacacacctc aaggcctcct gggggaggcc cggatgctca
1201 atgccagcat tgtggcatcc ttcgtggagc taccgctggc cagcattgtc tcacttcatg
1261 cctccagctg cggtggtagg ctgcagacct cacccgcacc gatccagacc actcctccca
1321 aggacacttg tagcccggag ctgctcatgt ccttgatcca gacaaagtgt gccgacgacg
1381 ccatgaccct ggtactaaag aaagagcttg ttgcgcattt gaagtgcacc atcacgggcc
1441 tgaccttctg ggaccccagc tgtgaggcag aggacagggg tgacaagttt gtcttgcgca
1501 gtgcttactc cagctgtggc atgcaggtgt cagcaagtat gatcagcaat gaggcggtgg
1561 tcaatatcct gtcgagctca tcaccacagc ggaaaaaggt gcactgcctc aacatggaca
1621 gcctctcttt ccagctgggc ctctacctca gcccacactt cctccaggcc tccaacacca
1681 tcgagccggg gcagcagagc tttgtgcagg tcagagtgtc cccatccgtc tccgagttcc
1741 tgctccagtt agacagctgc cacctggact tggggcctga gggaggcacc gtggaactca
1801 tccagggccg ggcggccaag ggcaactgtg tgagcctgct gtccccaagc cccgagggtg
1861 acccgcgctt cagcttcctc ctccacttct acacagtacc catacccaaa accggcaccc
1921 tcagctgcac ggtagccctg cgtcccaaga ccgggtctca agaccaggaa gtccatagga
1981 ctgtcttcat gcgcttgaac atcatcagcc ctgacctgtc tggttgcaca agcaaaggcc
2041 tcgtcctgcc cgccgtgctg ggcatcacct ttggtgcctt cctcatcggg gccctgctca
2101 ctgctgcact ctggtacatc tactcgcaca cgcgtgagta ccccaggccc ccacagtgag
2161 catgccgggc ccctccatcc acccggggga gcccagtgaa gcctctgagg gattgagggg
2221 ccctggcagg accctgacct ccgcccctgc ccccgctccc gctcccaggt tcccccagca
2281 agcgggagcc cgtggtggcg gtggctgccc cggcctcctc ggagagcagc agcaccaacc
2341 acagcatcgg gagcacccag agcaccccct gctccaccag cagcatggca tagccccggc
2401 cccccgcgct cgcccagcag gagagactga gcagccgcca gctgggagca ctggtgtgaa
2461 ctcaccctgg gagccagtcc tccactcgac ccagaatgga gcctgctctc cgcgcctacc
2521 cttcccgcct ccctctcaga ggcctgctgc cagtgcagcc actggcttgg aacaccttgg
2581 ggtccctcca ccccacagaa ccttcaaccc agtgggtctg ggatatggct gcccaggaga
2641 cagaccactt gccacgctgt tgtaaaaacc caagtccctg tcatttgaac ctggatccag
2701 cactggtgaa ctgagctggg caggaaggga gaacttgaaa cagattcagg ccagcccagc
2761 caggccaaca gcacctcccc gctgggaaga gaagagggcc cagcccagag ccacctggat
2821 ctatccctgc ggcctccaca cctgaacttg cctaactaac tggcagggga gacaggagcc
2881 tagcggagcc cagcctggga gcccagaggg tggcaagaac agtgggcgtt gggagcctag
2941 ctcctgccac atggagcccc ctctgccggt cgggcagcca gcagaggggg agtagccaag
3001 ctgcttgtcc tgggcctgcc cctgtgtatt caccaccaat aaatcagacc atgaaacctg
3061 aaaaaaaaaa aaa
//