LOCUS X71923 2668 bp mRNA linear HUM 14-NOV-2006
DEFINITION H.sapiens XB gene for tenascin-X, exons 1 & 2.
ACCESSION X71923
VERSION X71923.1
KEYWORDS EGF-like sequence; extracellular matrix protein; heptad repeat;
secreted protein; tenascin superfamily; tenascin-X; XB gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2668)
AUTHORS Bristow J.D.
JOURNAL Submitted (12-MAY-1993) to the INSDC. J.D. Bristow, University of
California, Dept of Pediatrics, Box 0544, 3rd and Parnassus Ave.,
San Francisco, CA 94143, USA
REFERENCE 2 (bases 1 to 2668)
AUTHORS Bristow J., Tee M.K., Gitelman S.E., Mellon S.H., Miller W.L.
TITLE Tenascin-X: a novel extracellular matrix protein encoded by the
human XB gene overlapping P450c21B
JOURNAL J. Cell Biol. 122(1), 265-278(1993).
PUBMED 7686164
COMMENT Related sequences: X60189 and X62489
FEATURES Location/Qualifiers
source 1..2668
/db_xref="H-InvDB:HIT000323173_04"
/organism="Homo sapiens"
/chromosome="6"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="cosmid library in pWE (stratagene)"
/clone="cTNX:5"
/note="class III region of MHC overlapping CYP21B and YB"
/db_xref="taxon:9606"
prim_transcript order(<1..>2668,X71924.1:<1..>476,X71928.1:<1..>117,
X71931.1:<1..>365,X71932.1:<1..>273)
/gene="XB"
exon <1..459
/number=1
mRNA join(<1..459,797..>2636)
CDS join(49..459,797..>2636)
/gene="XB"
/product="tenascin-X precursor"
/db_xref="GOA:P22105"
/db_xref="H-InvDB:HIT000323173_02.4"
/db_xref="HGNC:HGNC:11976"
/db_xref="InterPro:IPR000742"
/db_xref="InterPro:IPR002181"
/db_xref="InterPro:IPR003961"
/db_xref="InterPro:IPR013032"
/db_xref="InterPro:IPR013111"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR020837"
/db_xref="InterPro:IPR033081"
/db_xref="InterPro:IPR036056"
/db_xref="InterPro:IPR036116"
/db_xref="InterPro:IPR041161"
/db_xref="PDB:2CUH"
/db_xref="PDB:2CUI"
/db_xref="PDB:2CUM"
/db_xref="UniProtKB/Swiss-Prot:P22105"
/protein_id="CAA50739.1"
/translation="MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPG
GHTVGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQA
LRVRLEILEELVKGLKEQCTGGCCPASAQAGTGEQGQTDVRTLCSLHGVFDLSRCTCS
CEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGW
PSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGD
DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPG
YTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI
CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCEN
GVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRG
RCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGC
RGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTC
PSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCG
QEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCK
DGYAGEDCGE"
sig_peptide 49..117
/gene="XB"
/product="tenascin-X"
mat_peptide join(118..459,797..>2636)
/gene="XB"
/product="tenascin-X"
repeat_region 334..399
/note="heptad repeats"
intron 460..796
/number=1
exon 797..2636
/number=2
BASE COUNT 436 a 777 c 979 g 476 t
ORIGIN
1 cagagcaggt gcagaggcac tgcagctgct cggttgccca gcctctgaat gatgccagcc
61 cagtatgctc taacctccag cctggttctc ctggtgctgc tgagcacagc cagagcaggc
121 cccttctctt cacggtccaa tgtgacactg ccagcccccc ggccccctcc ccagccaggg
181 ggccacacag tgggggctgg agtgggaagc ccctcttctc agctttacga gcacacagtg
241 gaaggagggg agaagcaggt ggtattcacc caccgcatta acctgccccc ttccactggc
301 tgtggctgtc ccccaggcac cgagccccca gtccttgctt cagaggtaca ggccctgagg
361 gtccgtctag agatcctgga ggagttggtg aaggggctca aggaacagtg cactggggga
421 tgttgtcctg cctctgccca agctggcaca ggtgagcagg tgatcacaga agagggtgga
481 gaggtggggt ggggtgggca ttgctagtcc ataaaggtcc ttggtatgaa ttagaagaag
541 gcactccttc ctcaccgtga ggggtgtgga tgcagcccag aacacaactt ggagagcaga
601 gctgggctac atgtcaacca aagcatatgc gagggccctg agaggctgca tacattacac
661 atactagcaa ctgggagcag acatggcctt atgagatgag gctagcctgg ctaggggcct
721 gacactagga gcactacata ggctcagcct ctctcccagg agagagactg agacttgcct
781 ctcccctcct actccaggtc agacagatgt gcggaccctc tgcagtctcc atggtgtgtt
841 tgatctgagc cgctgcacct gttcctgtga gccaggctgg ggtgggccca cctgctcaga
901 ccccacagat gctgagatcc ctccctcttc cccaccctca gcctcggggt cctgcccaga
961 tgactgcaat gatcagggtc gctgtgtccg tggtcgttgc gtgtgctttc ccggctacac
1021 tggccccagc tgtggctggc catcctgtcc cggggactgc caaggccgtg ggcgctgcgt
1081 gcagggcgtg tgtgtgtgcc gggcaggctt ctcaggcccc gactgcagcc agcgctcctg
1141 ccctcgaggt tgcagccaga ggggacgctg tgagggtggg cgctgcgtgt gtgacccagg
1201 ctacactggt gacgactgtg gcatgaggag ctgccctcgc ggttgcagtc agagggggcg
1261 ctgtgagaat gggcgctgcg tgtgtaaccc cggctacact ggcgaggact gtggggtgag
1321 gagctgccct cggggctgca gccagcgggg acgctgcaag gacgggcgct gcgtgtgtga
1381 ccccggctac actggcgagg actgtggtac gcggagctgc ccctgggact gtggcgaggg
1441 cgggcgctgc gtggacggcc gctgcgtgtg ctggcccggg tacacaggcg aggactgcag
1501 cacgcggaca tgtccgaggg actgccgggg ccgcgggcgc tgcgaggacg gcgaatgcat
1561 ttgcgacacg ggctacagcg gggacgactg cggcgtgcgc agctgccctg gcgactgcaa
1621 ccaaaggggc cgctgcgagg acggccgctg cgtgtgctgg ccggggtaca ctggaaccga
1681 ttgcggctcg cgcgcctgcc cacgcgactg tagaggtcgc gggcgctgcg agaacggcgt
1741 gtgtgtttgc aatgcgggct acagcggcga ggactgcggt gtgcgcagct gtcctgggga
1801 ctgtcgtggc cggggccgct gtgagagtgg ccgctgcatg tgttggccgg ggtacacagg
1861 ccgggactgc ggcacgcgcg cctgtcctgg cgactgtcgc gggcgcgggc gctgcgtgga
1921 tggccgctgc gtgtgcaacc cgggcttcac cggtgaggac tgtgggagcc gtcgctgtcc
1981 cggggactgc cgtgggcacg gcctttgcga ggatggcgtg tgcgtgtgtg acgcaggcta
2041 ctcaggggaa gactgcagca cgcgcagctg ccccgggggc tgccgaggcc gcggccagtg
2101 cctagatggg cggtgtgtgt gcgaggacgg ctactctggc gaggattgcg gtgtgaggca
2161 gtgcccgaat gactgcagcc agcacggcgt gtgccaggac ggtgtgtgca tctgttggga
2221 aggctacgtg agtgaggact gcagcatccg cacctgcccc tccaactgcc acgggagggg
2281 ccgctgtgag gaagggcgct gcctgtgcga cccaggctac accggcccta cctgtgccac
2341 ccgcatgtgc ccggctgact gccggggacg tgggcggtgt gtgcaaggag tgtgcctgtg
2401 ccacgtgggc tatggcggtg aggactgcgg gcaggaagag cctccagcca gcgcctgccc
2461 tggaggctgc gggccccggg aactgtgccg ggcaggccag tgtgtgtgtg tagagggctt
2521 ccgaggccct gactgtgcca tccagacatg cccaggggac tgccgtggcc gaggagagtg
2581 tcacgatggc agctgtgtct gcaaagatgg gtatgctggc gaagactgcg gagaaggtga
2641 gcaggcagcc ttccccagtg tactctgg
//