LOCUS X69819 1817 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens ICAM-3 mRNA.
ACCESSION X69819
VERSION X69819.1
KEYWORDS ICAM-3 protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS de Fougerolles A.R., Klickstein L.B., Springer T.A.
TITLE Cloning and expression of ICAM-3 reveals strong homology to other
Ig family counter receptors for LFA1
JOURNAL Unpublished.
REFERENCE 2 (bases 1 to 1817)
AUTHORS de Fougerolles A.R.
JOURNAL Submitted (15-DEC-1992) to the INSDC. A.R. De Fougerolles, Centre
for Blood Research, East Quadrangle Res Facility Rm 250, 200
Longwood Avenue, Boston MA 02115, USA
COMMENT Conflicts to the sequence reported by Faqwcett, J. in Nature, 360,
481-484 and by Vazeux, R. in Nature, 360, 485-488
FEATURES Location/Qualifiers
source 1..1817
/db_xref="H-InvDB:HIT000323062"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda S2T, ATCC Acc# 37546"
/clone="lambda 14a2.2, lambda 7.3.1, lambda 11.2"
/tissue_type="tonsil"
/db_xref="taxon:9606"
CDS 9..1652
/gene="ICAM-3"
/db_xref="GOA:P32942"
/db_xref="H-InvDB:HIT000323062.14"
/db_xref="HGNC:HGNC:5346"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR003987"
/db_xref="InterPro:IPR003988"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013768"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036179"
/db_xref="PDB:1T0P"
/db_xref="UniProtKB/Swiss-Prot:P32942"
/protein_id="CAA49473.1"
/translation="MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLS
AGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNG
SQITGSSNITVYGLPERVELAPLPPWQPVGQNFTLRCQVEGGSPRTSLTVVLLRWEEE
LSRQPAVEEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVL
PVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTA
TATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTV
SCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSV
QLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPF
FVNVTHNGTYQCQASSSRGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLALMY
VFREHQRSGSYHVREESTYLPLTSMQPTEAMGEEPSRAE"
sig_peptide 9..95
misc_feature 195..221
/note="region encoding sequence of ICAM-3 lys-C cleaved
peptide 17"
misc_feature 1212..1244
/note="region encoding sequence of ICAM-3 lys-C cleaved
peptide 10"
misc_feature 1464..1538
/note="transmembrane region"
misc_feature 1539..1649
/note="cytoplasmic region"
BASE COUNT 423 a 524 c 542 g 328 t
ORIGIN
1 ctgtcagaat ggccaccatg gtaccatccg tgttgtggcc cagggcctgc tggactctgc
61 tggtctgctg tctgctgacc ccaggtgtcc aggggcagga gttccttttg cgggtggagc
121 cccagaaccc tgtgctctct gctggagggt ccctgtttgt gaactgcagt actgattgtc
181 ccagctctga gaaaatcgcc ttggagacgt ccctatcaaa ggagctggtg gccagtggca
241 tgggctgggc agccttcaat ctcagcaacg tgactggcaa cagtcggatc ctctgctcag
301 tgtactgcaa tggctcccag ataacaggct cctctaacat caccgtgtac gggctcccgg
361 agcgtgtgga gctggcaccc ctgcctcctt ggcagccggt gggccagaac ttcaccctgc
421 gctgccaagt ggagggtggg tcgccccgga ccagcctcac ggtggtgctg cttcgctggg
481 aggaggagct gagccggcag cccgcagtgg aggagccagc ggaggtcact gccactgtgc
541 tggccagcag agacgaccac ggagcccctt tctcatgccg cacagaactg gacatgcagc
601 cccaggggct gggactgttc gtgaacacct cagccccccg ccagctccga acctttgtcc
661 tgcccgtgac ccccccgcgc ctcgtggccc cccggttctt ggaggtggaa acgtcgtggc
721 cggtggactg caccctagac gggctttttc cagcctcaga ggcccaggtc tacctggcgc
781 tgggggacca gatgctgaat gcgacagtca tgaaccacgg ggacacgcta acggccacag
841 ccacagccac ggcgcgcgcg gatcaggagg gtgcccggga gatcgtctgc aacgtgaccc
901 tagggggcga gagacgggag gcccgggaga acttgacggt ctttagcttc ctaggaccca
961 ttgtgaacct cagcgagccc accgcccatg aggggtccac agtgaccgtg agttgcatgg
1021 ctggggctcg agtccaggtc acgctggacg gagttccggc cgcggccccg gggcagccag
1081 ctcaacttca gctaaatgct accgagagtg acgacggacg cagcttcttc tgcagtgcca
1141 ctctcgaggt ggacggcgag ttcttgcaca ggaacagtag cgtccagctg cgagtcctgt
1201 atggtcccaa aattgaccga gccacatgcc cccagcactt gaaatggaaa gataaaacga
1261 gacacgtcct gcagtgccaa gccaggggca acccgtaccc cgagctgcgg tgtttgaagg
1321 aaggctccag ccgggaggtg ccggtgggga tcccgttctt cgtcaacgta acacataatg
1381 gtacttatca gtgccaagcg tccagctcac gaggcaaata caccctggtc gtggtgatgg
1441 acattgaggc tgggagctcc cactttgtcc ccgtcttcgt ggcggtgtta ctgaccctgg
1501 gcgtggtgac tatcgtactg gccttaatgt acgtcttcag ggagcaccaa cggagcggca
1561 gttaccatgt tagggaggag agcacctatc tgcccctcac gtctatgcag ccgacagaag
1621 caatggggga agaaccgtcc agagctgagt gacgctggga tccgggatca aagttggcgg
1681 gggcttggct gtgccctcag attccgcacc aataaagcct tcaaactccc taaaaaaaaa
1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1801 aaaaaaaaaa aaaaaaa
//