LOCUS X69090 4949 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for skeletal muscle 190kD protein.
ACCESSION X69090
VERSION X69090.1
KEYWORDS fibronectin repeats; immunoglobulin superfamily; sarcomere M line;
titin binding.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Fuerst D.O.
JOURNAL Submitted (29-OCT-1992) to the INSDC. D.O. Fuerst, Max Planck
Institute for Biophysical Chemistry, Am Fassberg, 3400 Goettingen,
FRG
REMARK Revised by [3]
REFERENCE 2 (bases 1 to 3287)
AUTHORS Vinkemeier U., Obermann W., Weber K., Fuerst D.O.
TITLE The globular head domain of titin extends into the center of the
sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron
microscopy ot two titin-associated proteins
JOURNAL J. Cell Sci. 106, 319-330(1993).
PUBMED 7505783
REFERENCE 3 (bases 1 to 4949)
AUTHORS Fuerst D.O.
JOURNAL Submitted (24-JUN-1993) to the INSDC. D.O. Fuerst, Max Planck
Institute for Biophysical Chemistry, Am Fassberg, 3400 Goettingen,
FRG
FEATURES Location/Qualifiers
source 1..4949
/db_xref="H-InvDB:HIT000322959"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/tissue_type="skeletal muscle"
/db_xref="taxon:9606"
CDS 118..4473
/product="190kD protein"
/db_xref="GOA:P52179"
/db_xref="H-InvDB:HIT000322959.14"
/db_xref="HGNC:HGNC:7613"
/db_xref="InterPro:IPR003598"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR003961"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013098"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036116"
/db_xref="InterPro:IPR036179"
/db_xref="PDB:2R15"
/db_xref="PDB:2Y23"
/db_xref="PDB:2Y25"
/db_xref="PDB:3RBS"
/db_xref="PDB:5FM4"
/db_xref="PDB:5FM5"
/db_xref="PDB:5FM8"
/db_xref="UniProtKB/Swiss-Prot:P52179"
/protein_id="CAA48833.1"
/translation="MVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITT
PKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEK
KSRKVVIRGKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKL
HCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINACDFEDTAQYRASA
MNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFD
VSFGREGETMSLGCRVVITPEIKHFQPEIRWYRNGVPLSPSKWVQTLWSGERATLTFS
HLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIII
SWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA
VNKMGIGFPSRVSEAVAALDPAEKARLKSPLSTLDWTVIVTEEEPSEGIVPGPPTDLS
VTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLA
EGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEE
SKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVNAAGL
SEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYR
EVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKC
EEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEKAKEDQWRGL
NEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGRKEVVVNV
DDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG
IYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWM
QAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD
GKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKV
ANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDK
SRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNG
SAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEA
YAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKA
LAQTDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEA
RMAALESLKGGKKAK"
BASE COUNT 1415 a 1044 c 1324 g 1166 t
ORIGIN
1 cggacagatt ccagtctgct gttagatgat tattcatcca agttgagccc caaaccaaag
61 agagccaagc acagcctact gtctggagaa gagaaagaaa atttgcccag tgactacatg
121 gtacccattt tctcaggacg tcaaaagcat gtcagtggaa ttactgatac ggaagaagaa
181 agaattaagg aagctgctgc ttatatagcc cagaggaatc ttcttgctag tgaggaagga
241 atcacaacac ctaaacagtc cacggcatcc aagcagacca cggcatctaa gcagtccacg
301 gcatccaagc agtccacagc atccaagcag tccacggcat ccaggcagtc cacggcatcc
361 aggcagtctg tggtttccaa acaggccaca tccgctcttc aacaggaaga aacttctgaa
421 aagaagtcaa ggaaagttgt gattcgagga aaggcagaac gcctgtccct gaggaaaaca
481 ttagaagaaa ccgagacata tcatgccaag ctgaatgaag accatcttct ccatgctcct
541 gagtttatca ttaaacctcg ctcccacacg gtttgggaga aggagaatgt aaaattgcat
601 tgctccatag caggatggcc agaacctcgt gtcacgtggt ataaaaacca ggtgccaata
661 aatgtccatg caaaccctgg aaagtatatt attgagagtc gatatggaat gcacactctg
721 gagattaatg catgtgattt tgaagataca gctcagtacc gggcctcggc gatgaatgtt
781 aaaggagagc tttcggcata tgcttcagtt gtggtaaaaa ggtataaggg agagtttgat
841 gagactcgct tccatgctgg ggcttccacc atgcccctca gctttggtgt gaccccatat
901 ggttatgcat cccggtttga gatccacttt gatgacaaat ttgatgtgtc ttttgggaga
961 gagggagaga caatgagtct aggctgtcgt gttgtcatca ctcctgaaat taaacatttc
1021 cagccagaga tccggtggta cagaaatgga gtacctcttt ctccatcaaa atgggtgcaa
1081 acactttgga gtggagagcg ggcaacgctg acattttccc atctcaacaa agaagatgaa
1141 ggcctctata caatccgtgt acggatggga gaatattatg aacaatatag tgcttatgtc
1201 tttgttcgag atgctgatgc agagattgaa ggagccccag ctgctccctt ggatgtgaag
1261 tgcttggagg ccaacaaaga ttatatcatc atctcctgga aacagccagc tgtcgatgga
1321 gggagtccta ttctcggata ttttattgat aagtgtgagg tgggcacaga tagctggtcg
1381 cagtgcaatg acacacctgt gaagtttgct cgttttcctg tcactggatt gatcgaaggt
1441 cgttcctata tcttccgagt tcgagctgtg aataaaatgg gaataggttt cccatctcga
1501 gtttccgagg ccgtggctgc tctggatccg gctgagaaag ctagactaaa gtcgcccctc
1561 agcaccctgg actggacagt cattgttact gaagaggaac cttcagaggg tattgtgcct
1621 ggccccccga cagacctctc tgtcactgag gccacccgga gctatgtggt gctcagctgg
1681 aagccccctg gccagcgtgg tcatgagggc attatgtact ttgtggaaaa gtgtgaggca
1741 ggaacagaaa actggcagcg agtgaacacg gagctccctg tgaagtctcc ccgctttgct
1801 ctgtttgact tggccgaggg gaaatcctac tgtttccgtg tccgctgttc taattctgca
1861 ggagttggtg agccctcaga ggcaacggag gtgactgtgg taggggacaa acttgatatc
1921 cccaaggctc ctggcaaaat catcccaagc agaaacacag acacctcagt ggtagtttcg
1981 tgggaggagt ccaaagatgc caaagagctg gtcgggtact acatagaggc aaacgttgct
2041 ggctctggca agtgggagcc ctgtaacaac aaccccgtga aaactcaccg attcacttgt
2101 catggattag tgactggtca gagttatata ttccgggtca gagcagtcaa tgcagctgga
2161 cttagtgaat attcccagga ttcagaagct attgaagtca aagctgctat tgcaccacca
2221 tctccaccct gtgatatcac ctgtcttgaa agttttcgtg actcaatggt tcttggatgg
2281 aagcaaccag ataagactgg aggggcagaa attactggct attatgtgaa ctatcgcgag
2341 gtcattgatg gggtaccagg aaaatggaga gaagccaatg tcaaggctgt cagagaggag
2401 gcatacaaga ttagcaactt gaaggaaaac atggtgtatc agttccaagt ggcagccatg
2461 aacatggctg ggctgggcgc gccctccgca gtaagcgaat gcttcaaatg tgaagagtgg
2521 accatcgccg tcccaggacc accgcacagt ctcaagtgta gtgaagtcag gaaagactca
2581 ctggttctcc agtggaagcc gccagtccac tccgggcgga ctccggtcac tggttacttc
2641 gtggacttga aggagaaggc caaagaagac cagtggcgag ggctcaatga ggcggctatt
2701 aaaaacgtat acctgaaggt tcgaggcctc aaggagggcg tcagctacgt gttccgtgtt
2761 cgagccataa accaggcggg agttgggaag ccatctgacc ttgctggccc tgttgtggca
2821 gagacccgtc caggaaggaa agaggttgtt gtaaatgtgg atgatgatgg agtcatttca
2881 ttgaacttcg agtgtgataa gatgactcca aagtccgagt tctcctggtc caaagattat
2941 gtatccactg aggactctcc acgattggaa gtcgaaagca agggcaacaa gacgaaaatg
3001 accttcaaag accttgggat ggatgacttg ggtatttact cttgcgatgt aacagacact
3061 gatggaatag catcaagcta cttaatagat gaggaagaat tgaaacgttt acttgctctc
3121 agccatgaac acaagttccc aactgtccca gttaaatcag agttggcagt tgaaattttg
3181 gagaaaggcc aggtccggtt ttggatgcag gctgagaaac tgtctggcaa tgccaaagtc
3241 aactacatat ttaacgagaa ggaaattttt gaaggcccga aatataaaat gcatattgac
3301 cgaaacactg gcatcatcga aatgttcatg gaaaagctac aggatgagga tgagggaacg
3361 tacactttcc agcttcaaga tggaaaagca actaaccatt ctactgttgt tctcgttgga
3421 gatgttttca aaaagctcca gaaagaagct gaattccagc ggcaagaatg gatcaggaaa
3481 caaggtcctc actttgttga gtatttgagc tgggaagtga ctggtgaatg taatgtacta
3541 ttgaaatgca aggtggcaaa tattaagaag gagactcata ttgtgtggta caaagatgag
3601 agggagatat cagtggatga aaagcatgac tttaaggatg gtatatgtac cctgcttata
3661 acagagtttt ccaagaaaga tgctgggatt tatgaagtta tcctgaaaga tgaccgagga
3721 aaagataaga gcagactgaa gcttgtggat gaagccttta aggaactgat gatggaagta
3781 tgcaaaaaaa tagctttgtc tgctacagac ctgaaaatcc agagcacagc cgagggcatc
3841 caactgtact cttttgtaac ttactatgtg gaggatttga aagttaactg gtcccacaat
3901 gggtccgcca ttaggtactc agacagagtt aagaccgggg tcactggaga gcagatctgg
3961 ctacaaatca acgagcccac cccgaatgac aaagggaagt atgtcatgga gctctttgat
4021 ggcaaaactg gacatcagaa gacagtggat ctctctggac aagcatacga tgaggcctat
4081 gctgaattcc agaggttgaa acaagctgcc attgccgaga aaaatcgtgc ccgggtgttg
4141 ggaggtctcc cagacgtggt caccatccag gaggggaagg cccttaatct cacttgcaac
4201 gtgtggggag acccgcctcc ggaggtgtcg tggttgaaga acgagaaggc cctggctcag
4261 acggaccact gcaacctcaa gttcgaggct gggaggaccg cgtacttcac catcaacggt
4321 gtgagcaccg ctgactcggg caaatacggg ctggttgtga agaacaagta tggctcggag
4381 accagcgact tcaccgtcag cgtgttcatc ccagaggagg aggcgaggat ggccgccttg
4441 gagtccctga aaggtggcaa gaaggccaag tgaccggagg tgcgaggaga gcagccggcc
4501 tgtgtgactt gggtgtgaat ggtttgggtt aaggatgaga cgtccttcat gcttctcctc
4561 cctattattt ctggcttgag ggaaataatg tcaggtcttt cactcatata aaaaagcacc
4621 aactaatgac actttaattg tttttcttta tctacaaaat tatgtgttaa gaaaatacca
4681 ttcatagcat gaagattagg aaacagtttt aaggagaaga cttgaatgaa gttggaggga
4741 cattgaatga tggtcagagg gcagacgaat gtgtcgtggg gcggaattgg gatttgctgc
4801 agctgtgaag ccatggccgt gtctcgtgtg ttgttacaga ggtgatgtgc ttttcgacgg
4861 gccctcgtgg cttggaacct cctctgtatg aataaacagt tttcacgtct gtcctcttcc
4921 ccgaaaaaaa aaaaaaaaaa aaaaaaaaa
//