LOCUS X66785 3535 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for transacylase (DBT).
ACCESSION X66785 S48130
VERSION X66785.1
KEYWORDS transacylase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3535)
AUTHORS Lau K.S.
JOURNAL Submitted (07-JUN-1992) to the INSDC. K.S. Lau, University of
Texas, Southwestern Medical Center, Dept of Biochemistry, 5323
Harry Hines Blvd, Dallas TX 75235-9038, USA
REFERENCE 2
AUTHORS Lau K.S., Chuang J.L., Herring W.J., Danner D.J., Cox R.P.,
Chuang D.T.
TITLE The complete cDNA sequence for dihydrolipoyl transacylase (E2) of
human branched-chain alpha-keto acid dehydrogenase complex
JOURNAL Biochim. Biophys. Acta 1132(3), 319-321(1992).
PUBMED 1420314
FEATURES Location/Qualifiers
source 1..3535
/db_xref="H-InvDB:HIT000322842"
/organism="Homo sapiens"
/chromosome="1p31"
/mol_type="mRNA"
/tissue_type="kidney"
/db_xref="taxon:9606"
CDS 15..1463
/gene="DBT"
/product="transacylase"
/note="product subunit structure 24mer, mitochondrial
multi-enzyme complex"
/db_xref="GOA:P11182"
/db_xref="H-InvDB:HIT000322842.14"
/db_xref="HGNC:HGNC:2698"
/db_xref="InterPro:IPR000089"
/db_xref="InterPro:IPR001078"
/db_xref="InterPro:IPR003016"
/db_xref="InterPro:IPR004167"
/db_xref="InterPro:IPR011053"
/db_xref="InterPro:IPR023213"
/db_xref="InterPro:IPR036625"
/db_xref="PDB:1K8M"
/db_xref="PDB:1K8O"
/db_xref="PDB:1ZWV"
/db_xref="PDB:2COO"
/db_xref="PDB:3RNM"
/db_xref="UniProtKB/Swiss-Prot:P11182"
/protein_id="CAA47285.1"
/translation="MAAVRMLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPS
FKYSHPHHFLKTTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQ
SDKASVTITSRYDGVIKKLYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDE
HTHQEIKGRKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILP
PSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHF
GYCDEIDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQ
NITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLT
GGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSA
DHRVIDGATMSRFSNLWKSYLENPAFMLLDLK"
repeat_region 1763..2032
/rpt_family="Alu 1"
regulatory 2901..2906
/regulatory_class="polyA_signal_sequence"
regulatory 2923..2928
/regulatory_class="polyA_signal_sequence"
repeat_region 2954..3054
/rpt_family="Alu 2"
repeat_region 3073..3359
/rpt_family="Alu 3"
BASE COUNT 1105 a 644 c 763 g 1023 t
ORIGIN
1 atttccgggg taagatggct gcagtccgta tgctgagaac ctggagcagg aatgcgggga
61 agctgatttg tgttcgctat tttcaaacat gtggtaatgt tcatgttttg aagccaaatt
121 atgtgtgttt ctttggttat ccttcattca agtatagtca tccacatcac ttcctgaaaa
181 caactgctgc tctccgtgga caggttgttc agttcaagct ctcagacatt ggagaaggga
241 ttagagaagt aactgttaaa gaatggtatg taaaagaagg agatacagtg tctcagtttg
301 atagcatctg tgaagttcaa agtgataaag cttctgttac catcactagt cgttatgatg
361 gagtcattaa aaaactctat tataatctag acgatattgc ctatgtgggg aagccattag
421 tagacataga aacggaagct ttaaaagatt cagaagaaga tgttgttgaa actcctgcag
481 tgtctcatga tgaacataca caccaagaga taaagggccg aaaaacactg gcaactcctg
541 cagttcgccg tctggcaatg gaaaacaata ttaagctgag tgaagttgtt ggctcaggaa
601 aagatggcag aatacttaaa gaagatatcc tcaactattt ggaaaagcag acaggagcta
661 tattgcctcc ttcacccaaa gttgaaatta tgccacctcc accaaagcca aaagacatga
721 ctgttcctat actagtatca aaacctccgg tattcacagg caaagacaaa acagaaccca
781 taaaaggctt tcaaaaagca atggtcaaga ctatgtctgc agccctgaag atacctcatt
841 ttggttattg tgatgagatt gaccttactg aactggttaa gctccgagaa gaattaaaac
901 ccattgcatt tgctcgtgga attaaactct cctttatgcc tttcttctta aaggctgctt
961 ccttgggatt actacagttt cctatcctta acgcttctgt ggatgaaaac tgccagaata
1021 taacatataa ggcttctcat aacattggga tagcaatgga tactgagcag ggtttgattg
1081 tccctaatgt gaaaaatgtt cagatctgct ctatatttga catcgccact gaactgaacc
1141 gcctccagaa attgggctct gtgggtcagc tcagcaccac tgatcttaca ggaggaacat
1201 ttactctttc caacattgga tcaattggtg gtacctttgc caaaccagtg ataatgccac
1261 ctgaagtagc cattggggcc cttggatcaa ttaaggccat tccccgattt aaccagaaag
1321 gagaagtata taaggcacag ataatgaatg tgagctggtc agctgatcac agagttattg
1381 atggtgctac aatgtcacgc ttctccaatt tgtggaaatc ctatttagaa aacccagctt
1441 ttatgctact agatctgaaa tgaagactga taagacattc ttgaactttt tgagcttcca
1501 aagagtatgt aaaccctagc tgtgccagca catgttcatc tttacaattt atattgtaaa
1561 cgatttgtat cgtatgatta aggatctaag gcacaatatt tgtcactgtt ctattagact
1621 ttttactgaa aatgaataat ggtgtaatgg ttctcctggg gctgtcacat tttataggtc
1681 agagtgtgac ttcttaatat ggtgctgatg tttttgtgtc aatggcttga aactggcaag
1741 attaacaaaa ttaggccggg catggtggct cacgcctgta atccagcact ttgggaggcc
1801 caggtggggc gatcacctga ggttagaagt ttgagaccag cctggccaac atggtgaaac
1861 ctggcctcta cctaaaaaat acaaaattga ccgggtgtgg tggtgggtac cgctacttgg
1921 gaggctgagg caggagaatc gcttgaacct gggaggtgga ggttgcagtg agctgagatc
1981 gtgctattgc actccagcct gggcgacaga gcaagacgcc atctcaaaaa caaaaaaaac
2041 aaaattcatg ttactaaaag acaggtagcc atatacagac agtatatgcc ctattttttt
2101 taactgactc ttaatgaaac tttaatttta cttaattaag aaatggaatt tatatacaaa
2161 aatattttcc atttccgtta ttatgctaat tgttgtatga aataagtgca attatacttc
2221 tcttttgaga tatccaagag tatattcttg ctctgtatag agaatatcat ctgatagtgt
2281 cttatttata ttaattaatg tctttgaaaa gggaaaagta taaactggcc ttaaaattgt
2341 ccaattatag ttttataacc agtctattaa aggtgtttgt ttaaaatgga tatagtttta
2401 gatttgtggt aatgctttgg tattttcttg gggaagacct tcacctttgc aaacttccct
2461 catgtaagga aggtacttta aatgtagcag ccactgacat ttcttttttt aaaaaaaatt
2521 tgagaagtct acttcctttt aacttttttg gtcttcagct aaaaaatagg ataagaaatt
2581 aaggtctatt ccattctcca tatcctgggt aagaatgtaa ataagaggag aaggaagagt
2641 ctaatagtaa ttatggatat aaaaaataag aaattttgta tagaaatgaa ggtttcataa
2701 tgatcatttt gttaaaggtc tactttaatc agaaatagca acgagatgaa tgtatccaac
2761 atttcaattt gcattcggaa atccatgttg tttctaatat tgtccagttg aaaactgtat
2821 gccaaaatta gttgtttaag tgaagttttg tgacagaaaa aaggttgttt taatatctac
2881 ttggtttttc tcaaaatgga aataatttta aaatcaggaa agaataaatc agccaggtgt
2941 gatgacttgt aactgtaatc ccagttatag gggaggctga agcaggagga tcacttgagg
3001 ccaggagttt gagaccagcc tgggcaacat agtgagatcc catctcaaaa aacattattt
3061 ttaaaattag cctggtggct cacgcctgta atcccagcac tttgggaggc cgaggtggcc
3121 agatcacctg aggtcaggag ttcgagacca ccctggccaa catggtgaaa ccccatctct
3181 acagttttgt aaaaatacaa aaattacctg ggcctggtgc acaggcctgt agtcccagct
3241 acttgggagg ctgaggcagg agaattgctt gagcccaaga ggtggaggtt acagtgagca
3301 gagatcacac cactgcactc cagcctgggt ggcagagcaa cacttcgtct cagaaaaaaa
3361 aaaaaaaacc aaaaaccaaa aagccaagtg tggtggtgtg cacctatagt cccagctact
3421 caggaagctg agacaagagg atcaattgag cccaggagtt caaagctgta gtgagctgtc
3481 attgtgccac tatcctccag tatgggtgac agagtgagac ctggtctcta aaaat
//