LOCUS X65964 4854 bp DNA linear HUM 12-MAY-1992
DEFINITION H.sapiens nestin gene.
ACCESSION X65964
VERSION X65964.1
KEYWORDS nestin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4854)
AUTHORS Dahlstrand J.
JOURNAL Submitted (04-MAY-1992) to the INSDC. J. Dahlstrand, Dept.of Mol
Genetics, CMB, Karolinska Institutet, Box 604 00, S-104 01
Stockholm, SWEDEN
REFERENCE 2
AUTHORS Dahlstrand J., McKay R.D.G., Zimmerman L.B., Lendahl U.
TITLE Characterization of the human nestin gene reveals a close
evolutionary relationship to neurofilaments
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..4854
/organism="Homo sapiens"
/mol_type="genomic DNA"
/dev_stage="adult"
/clone_lib="genomic"
/tissue_type="placenta"
/db_xref="taxon:9606"
CDS 1..>4854
/product="nestin"
/db_xref="GOA:P48681"
/db_xref="HGNC:HGNC:7756"
/db_xref="InterPro:IPR018039"
/db_xref="InterPro:IPR031211"
/db_xref="InterPro:IPR039008"
/db_xref="InterPro:IPR042180"
/db_xref="UniProtKB/Swiss-Prot:P48681"
/protein_id="CAA46780.1"
/translation="MEGCMGEESFQMWELNRRLEAYLGRVKALEEQNELLSAGLGGLR
RQSADTSWRAHADDELAALRALVDQRWREKHAAEVARDNLAEELEGVAGRCEQLRLAR
ERTTEEVARNRRAVEAEKCARAWLSSQGAELERELEALRVAHEEERVGLNAQAACAPR
LPAPPRPPAPAPEVEELARRLGEAWRGAVRGYQERVAHMETSLDQTRERLARAVQGAR
EVRLELQQLQAERGGLLERRAALEQRLEGRWQERLRATEKFQLAVEALEQEKQGLQSQ
IAQVLEGRQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGGGSKTSLSFQDPKLELQF
PRTPEGRRLGSLLPVLSPTSLPSPLPATLETPVPAFLKNQEFLQARTPTLASTPIPPT
PQAPSPAVDAEIRAQDAPLSLLQTQGGRKQAPEPLRAEARVAIPASVLPGPEEPGGQR
QEASTGQSPEDHASLAPPLSPDHSSLEAKDGESGGSRVFSICRGEGEGQIWGLVEKET
AIEGKVVSSLQQEIWEEEDLNRKEIQDSQVPLEKETLKSLGEEIQESLKTLENQSHET
LERENQECPRSLEEDLETLKSLEKENKRAIKGCGGSETSRKRGCRQLKPTGKEDTQTL
QSLQKENQELMKSLEGNLETFLFPGTENQELVSSLQENLESLTALEKENQEPLRSPEV
GDEEALRPLTKENQEPLRSLEDENKEAFRSLEKENQEPLKTLEEEDQSIVRPLETENH
KSLRSLEEQDQETLRTLEKETQQRRRSLGEQDQMTLRPPEKVDLEPLKSLDQEIARPL
ENENQEFLKSLKEESVEAVKSLETEILESLKSAGQENLETLKSPETQAPLWTPEEINK
SGGNESSRKGNSRTTGVCGSEPRDIQTPGRGESGIIEISGSMEPGEFEISRGVDKESQ
RNLEEEENLGKGEYQESLRSLEEEGQELPQSADVQRWEDTVEKDQELAQESPPGMAGV
ENKDEAELNLREQDGFTGKEEVVEQGELNATEEVWFPGEGHPENPEPKEQRGLVEGAS
VKGGAEGLQDPEGQSQQVGTPGLQAPQGLPEAIEPLVEDDVAPGGDQASPEVMLGSEP
AMGESAAGAEPGLGQGVGGLGDPGHLTREEVMEPPLEEESLEAKRVQGLEGPRKDLEE
AGGLGTEFSELPGKSRDPWEPPREGREESEAEAPRGAEEAFPAETLGHTGSDAPSPWP
LGSEEAEEDVPPVLVSPSPTYTPILEDAPGLQPQAEGSQEASWGVQGRAEAGKVESEQ
EELGSGEIPEGLQEEGEESREESEEDELGETLPDSTPLGFYLRSPTSPRWTPLESRGH
PLKETGKEGWDPAVLASEGLEEPSEKEEGEEGEEECGRDSDLSEEFEDLGTEAPFLPG
VPGEVAEPLGQVPQLLLDPAAWDRDGESDGFADEEESGEEGEEDQEEGREPGAGRWGP
GSSVGSLQALSSSQRGEFLESDSVSVSVPWDDSLRGAVAGAPKTALETESQDSAEPSG
SEEESDPVSLEREDKVPGPLEIPSGMEDAGPGADIIGVNGQGPNLEGKSQHVNGGVMN
GLEQSEESGARNALVSEGDRGSPFQEEEGSALKRSSAGAPVHLGQGQFLKFTQREGDR
ESWSSGED"
BASE COUNT 1238 a 1176 c 1676 g 764 t
ORIGIN
1 atggagggct gcatggggga ggagtcgttt cagatgtggg agctcaatcg gcgcctggag
61 gcctacctgg gccgggtcaa ggcgctggag gagcagaatg agctgctcag cgccggactc
121 ggggggctcc ggcgacaatc cgcggacacc tcctggcggg cgcatgccga cgacgagctg
181 gcggccctgc gtgcgctcgt tgaccaacgc tggcgggaga agcacgcggc cgaggtggcg
241 cgcgacaacc tggctgaaga gctggagggc gtggcaggcc gatgcgagca gctgcggctg
301 gcccgggagc ggacgacgga ggaggtagcc cgcaaccggc gcgccgtcga ggcagagaaa
361 tgcgcccggg cctggctgag tagccagggg gcagagctgg agcgcgagct agaggctcta
421 cgcgtggcgc acgaggagga gcgcgtcggt ctgaacgcgc aggctgcctg tgccccccgc
481 ctgcccgcgc cgccccggcc tcccgcgccg gccccggagg tagaggagct ggcaaggcga
541 ctgggcgagg cgtggcgcgg ggcagtgcgc ggctaccagg agcgcgtggc acacatggag
601 acgtcgctgg accagacccg cgagcgcctg gcccgggcgg tgcagggtgc ccgcgaggtc
661 cgcctggagc tgcagcagct ccaggctgag cgcggaggcc tcctggagcg cagggcagcg
721 ttggaacaga ggttggaggg ccgctggcag gagcggctgc gggctactga aaagttccag
781 ctggctgtgg aggccctgga gcaggagaaa cagggcctac agagccagat cgctcaggtc
841 ctggaaggtc ggcagcagct ggcgcacctc aagatgtccc tcagcctgga ggtggccacg
901 tacaggaccc tcctggaggc tgagaactcc cggctgcaaa cacctggcgg tggctccaag
961 acttccctca gctttcagga ccccaagctg gagctgcaat tccctaggac cccagagggc
1021 cggcgtcttg gatctttgct cccagtcctg agcccaactt ccctcccctc acccttgcct
1081 gctacccttg agacacctgt gccagccttt cttaagaacc aagaattcct ccaggcccgt
1141 acccctacct tggccagcac ccccatcccc cccacacctc aggcaccctc tcctgctgta
1201 gatgcagaga tcagagccca ggatgctcct ctctctctgc tccagacaca gggtgggagg
1261 aaacaggctc cagagcccct gcgggctgaa gccagggtgg ccattcctgc cagcgtcctg
1321 cctggaccag aggagcctgg gggccagcgg caagaggcca gtacaggcca gtccccagag
1381 gaccatgcct ccttggcacc acccctcagc cctgaccact ccagtttaga ggctaaggat
1441 ggagaatccg gtgggtctag agtgttcagc atatgccgag gggaaggtga agggcaaatc
1501 tgggggttgg tagagaaaga aacagccata gagggcaaag tggtaagcag cttgcagcag
1561 gaaatatggg aagaagagga tctaaacagg aaggaaatcc aggactccca ggttcctttg
1621 gaaaaagaaa ccctgaagtc tctgggagag gagattcaag agtcactgaa gactctggaa
1681 aaccagagcc atgagacact agaaagggag aatcaagaat gtccgaggtc tttagaagaa
1741 gacttagaaa cactaaaaag tctagaaaag gaaaataaaa gagctattaa aggatgtgga
1801 ggtagtgaga cctctagaaa aagaggctgt aggcaactta agcctacagg aaaagaggac
1861 acacagacat tgcaatccct gcaaaaggag aatcaagaac taatgaaatc tcttgaaggt
1921 aatctagaga catttttatt tccaggaacg gaaaatcaag aattagtaag ttctctgcaa
1981 gagaacttag agtcattgac agctctggaa aaggagaatc aagagccact gagatctcca
2041 gaagtagggg atgaggaggc actgagacct ctgacaaagg agaatcagga acccctgagg
2101 tctcttgaag atgagaacaa agaggccttt agatctctag aaaaagagaa ccaggagcca
2161 ctgaagactc tagaagaaga ggaccagagt attgtgagac ctctagaaac agagaatcac
2221 aaatcactga ggtctttaga agaacaggac caagagacat tgagaactct tgaaaaagag
2281 actcaacagc gacggaggtc tctaggggaa caggatcaga tgacattaag acccccagaa
2341 aaagtggatc tagaaccact gaagtctctt gaccaggaga tagctagacc tcttgaaaat
2401 gagaatcaag agttcttaaa gtcactcaaa gaagagagcg tagaggcagt aaaatcttta
2461 gaaacagaga tcctagaatc actgaagtct gcgggacaag agaacctgga aacactgaaa
2521 tctccagaaa ctcaagcacc actgtggact ccagaagaaa taaataaatc agggggcaat
2581 gaatcctcta gaaaaggaaa ttcaagaacc actggagtct gtggaagtga accaagagac
2641 attcagactc ctggaagagg agaatcagga atcattgaga tctctgggag catggaacct
2701 ggagaatttg agatctccag aggagtagac aaggaaagtc aaaggaatct ggaagaggaa
2761 gagaacctgg gaaagggaga gtaccaagag tcactgaggt ctctggagga ggagggacag
2821 gagctgccgc agtctgcaga tgtgcagagg tgggaagata cggtggagaa ggaccaagaa
2881 ctggctcagg aaagccctcc tgggatggct ggagtggaaa ataaggatga ggcagagctg
2941 aatctaaggg agcaggatgg cttcactggg aaggaggagg tggtagagca gggagagctg
3001 aatgccacag aggaggtctg gttcccaggc gaggggcacc cagagaaccc tgagcccaaa
3061 gagcagagag gcctggttga gggagccagt gtgaagggag gggctgaggg cctccaggac
3121 cctgaagggc aatcacaaca ggtggggacc ccaggcctcc aggctcccca ggggctgcca
3181 gaggcgatag agcccctggt ggaagatgat gtggccccag ggggtgacca agcctcccca
3241 gaggtcatgt tggggtcaga gcctgccatg ggtgagtctg ctgcgggagc tgagccaggc
3301 ctggggcagg gggtgggagg gctgggggac ccaggccatc tgaccaggga agaggtgatg
3361 gaaccacccc tggaagagga gagtttggag gcaaagaggg ttcagggctt ggaagggcct
3421 agaaaggacc tagaggaggc aggtggtctg gggacagagt tctccgagct gcctgggaag
3481 agcagagacc cttgggagcc tcccagggag ggtagggagg agtcagaggc tgaggccccc
3541 aggggagcag aggaggcgtt ccctgctgag accctgggcc acactggaag tgatgcccct
3601 tcaccttggc ctctggggtc agaggaagct gaggaggatg taccaccagt gctggtctcc
3661 cccagcccaa cgtacacccc gatcctggaa gatgcccctg ggctccagcc tcaggctgaa
3721 gggagtcagg aggctagctg gggggtgcag gggagggctg aagctgggaa agtagagagc
3781 gagcaggagg agttgggttc tggggagatc cccgagggcc tccaggagga aggggaggag
3841 agcagagaag agagcgagga ggatgagctc ggggagaccc ttccagactc cactcccctg
3901 ggcttctacc tcaggtcccc cacctccccc aggtggaccc cactggagag cagaggccac
3961 cccctcaagg agactggaaa ggagggctgg gatcctgctg tcctggcttc cgagggcctt
4021 gaggaaccct cagaaaagga ggagggggag gagggagaag aggagtgtgg ccgtgactct
4081 gacctgtcag aagaatttga ggacctgggg actgaggcac cttttcttcc tggggtccct
4141 ggggaggtgg cagaacctct gggccaggtg ccccagctgc tactggatcc tgcagcctgg
4201 gatcgagatg gggagtctga tgggtttgca gatgaggaag aaagtgggga ggagggagag
4261 gaggatcagg aggaggggag ggagccaggg gctgggcggt gggggccagg gtcttctgtt
4321 ggcagcctcc aggccctgag tagctcccag agaggggaat tcctggagtc tgattctgta
4381 agtgtcagcg tcccctggga tgacagcttg aggggtgcag tggctggtgc ccccaagact
4441 gccctggaaa cggagtccca ggacagtgct gagccttctg gctcagagga agagtctgac
4501 cctgtttcct tggagaggga ggacaaagtc cctggccctc tagagatccc cagtgggatg
4561 gaggatgcag gcccaggggc agacatcatt ggtgttaatg gccagggtcc caacttggag
4621 gggaagtcac agcatgtaaa tgggggagta atgaacgggc tggagcagtc tgaggaaagt
4681 ggggcaagga atgcgctagt ctctgaggga gaccgaggga gcccctttca ggaggaggag
4741 gggagtgctc tgaagaggtc ttcggcaggg gctcctgttc acctgggcca gggtcagttc
4801 ctgaagttca ctcagaggga aggagataga gagtcctggt cctcagggga ggac
//