LOCUS X65873 3688 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for kinesin (heavy chain).
ACCESSION X65873
VERSION X65873.1
KEYWORDS kinesin; kinesin heavy chain.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3688)
AUTHORS Vale R.D.
JOURNAL Submitted (28-APR-1992) to the INSDC. R.D. Vale, Univ of California
at San Francisco, Dept of Pharmacology, Box 0450, San Francisco CA
94143, USA
REFERENCE 2 (bases 1 to 3688)
AUTHORS Navone F., Niclas J., Hom-Booher N., Sparks L., Bernstein H.,
McCaffrey G., Vale R.
TITLE Cloning and expression of a human kinesin heavy chain gene:
interaction of the COOH-terminal domain with cytoplasmic
microtubules in transfected CV-1 cells
JOURNAL J. Cell Biol. 117(6), 1263-1275(1992).
PUBMED 1607388
FEATURES Location/Qualifiers
source 1..3688
/db_xref="H-InvDB:HIT000322766"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone="HK-3, HK-21, HK-H8"
/tissue_type="placenta"
/db_xref="taxon:9606"
CDS 314..3205
/product="kinesin heavy chain"
/db_xref="GOA:P33176"
/db_xref="H-InvDB:HIT000322766.14"
/db_xref="HGNC:HGNC:6324"
/db_xref="InterPro:IPR001752"
/db_xref="InterPro:IPR019821"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR027640"
/db_xref="InterPro:IPR036961"
/db_xref="PDB:1BG2"
/db_xref="PDB:1MKJ"
/db_xref="PDB:2P4N"
/db_xref="PDB:3J8X"
/db_xref="PDB:3J8Y"
/db_xref="PDB:4HNA"
/db_xref="PDB:4LNU"
/db_xref="PDB:5LT0"
/db_xref="PDB:5LT1"
/db_xref="PDB:5LT2"
/db_xref="PDB:5LT3"
/db_xref="PDB:5LT4"
/db_xref="UniProtKB/Swiss-Prot:P33176"
/protein_id="CAA46703.1"
/translation="MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASK
PYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP
EGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKN
RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQ
TEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVP
YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVE
LTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTV
DKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQE
VEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIG
IAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEE
NEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHE
MEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKM
MLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHN
LRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADL
RCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARR
GHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNSQPVAVRGGGGKQV"
BASE COUNT 1317 a 694 c 839 g 838 t
ORIGIN
1 ccagcccccg cagtccgccc agaccgtaaa gggggacgct gaggagccgc ggacgctctc
61 cccggtgccg ccgccgctgc cgccgccatg gctgccatga tggatcggaa gtgagcatta
121 gggttaacgg ctgccggcgc cggctcttca agtcccggct ccccggccgc ctccacccgg
181 ggaacgcgag cgcggcgcag ctgactgctg cctctcacgg ccctcgcgac cacaagccct
241 caggtccggc gcgttccctg caagactgag cggcggggag tggctcccgg ccgcggcccc
301 ggctgcgaga aagatggcgg acctggccga gtgcaacatc aaagtgatgt gtcgcttcag
361 acctctcaac gagtctgaag tgaaccgcgg cgacaagtac atcgccaagt ttcagggaga
421 agacacggtc gtgatcgcgt ccaagcctta tgcatttgat cgggtgttcc agtcaagcac
481 atctcaagag caagtgtata atgactgtgc aaagaagatt gttaaagatg tacttgaagg
541 atataatgga acaatatttg catatggaca aacatcctct gggaagacac acacaatgga
601 gggtaaactt catgatccag aaggcatggg aattattcca agaatagtgc aagatatttt
661 taattatatt tactccatgg atgaaaattt ggaatttcat attaaggttt catattttga
721 aatatatttg gataagataa gggacctgtt agatgtttca aagaccaacc tttcagttca
781 tgaagacaaa aaccgagttc cctatgtaaa ggggtgcaca gagcgttttg tatgtagtcc
841 agatgaagtt atggatacca tagatgaagg aaaatccaac agacatgtag cagttacaaa
901 tatgaatgaa catagctcta ggagtcacag tatatttctt attaatgtca aacaagagaa
961 cacacaaacg gaacaaaagc tgagtggaaa actttatctg gttgatttag ctggtagtga
1021 aaaggttagt aaaactggag ctgaaggtgc tgtgctggat gaagctaaaa acatcaacaa
1081 gtcactttct gctcttggaa atgttatttc tgctttggct gagggtagta catatgttcc
1141 atatcgagat agtaaaatga caagaatcct tcaagattca ttaggtggca actgtagaac
1201 cactattgta atttgctgct ctccatcatc atacaatgag tctgaaacaa aatctacact
1261 cttatttggc caaagggcca aaacaattaa gaacacagtt tgtgtcaatg tggagttaac
1321 tgcagaacag tggaaaaaga agtatgaaaa agaaaaagaa aaaaataaga tcctgcggaa
1381 cactattcag tggcttgaaa atgagctcaa cagatggcgt aatggggaga cggtgcctat
1441 tgatgaacag tttgacaaag agaaagccaa cttggaagct ttcacagtgg ataaagatat
1501 tactcttacc aatgataaac cagcaaccgc aattggagtt ataggaaatt ttactgatgc
1561 tgaaagaaga aagtgtgaag aagaaattgc taaattatac aaacagcttg atgacaagga
1621 tgaagaaatt aaccagcaaa gtcaactggt agagaaactg aagacgcaaa tgttggatca
1681 ggaggagctt ttggcatcta ccagaaggga tcaagacaat atgcaagctg agctgaatcg
1741 ccttcaagca gaaaatgatg cctctaaaga agaagtgaaa gaagttttac aggccctaga
1801 agaacttgct gtcaattatg atcagaagtc tcaggaagtt gaagacaaaa ctaaggaata
1861 tgaattgctt agtgatgaat tgaatcagaa atcggcaact ttagcgagta tagatgctga
1921 gcttcagaaa cttaaggaaa tgaccaacca ccagaaaaaa cgagcagctg agatgatggc
1981 atctttacta aaagaccttg cagaaatagg aattgctgtg ggaaataatg atgtaaagca
2041 gcctgaggga actggcatga tagatgaaga gttcactgtt gcaagactct acattagcaa
2101 aatgaagtca gaagtaaaaa ccatggtgaa acgttgcaag cagttagaaa gcacacaaac
2161 tgagagcaac aaaaaaatgg aagaaaatga aaaggagtta gcagcatgtc agcttcgtat
2221 ctctcaacat gaagccaaaa tcaagtcatt gactgaatac cttcaaaatg tggaacaaaa
2281 gaaaagacag ttggaggaat ctgtcgatgc cctcagtgaa gaactagtcc agcttcgagc
2341 acaagagaaa gtccatgaaa tggaaaagga gcacttaaat aaggttcaga ctgcaaatga
2401 agttaagcaa gctgttgaac agcagatcca gagccataga gaaactcatc aaaaacagat
2461 cagtagtttg agagatgaag tagaagcaaa agcaaaactt attactgatc ttcaagacca
2521 aaaccagaaa atgatgttag agcaggaacg tctaagagta gaacatgaga agttgaaagc
2581 cacagatcag gaaaagagca gaaaactaca tgaacttacg gttatgcaag atagacgaga
2641 acaagcaaga caagacttga agggtttgga agagacagtg gcaaaagaac ttcagacttt
2701 acacaacctg cgcaaactct ttgttcagga cctggctaca agagttaaaa agagtgctga
2761 gattgattct gatgacaccg gaggcagcgc tgctcagaag caaaaaatct cctttcttga
2821 aaataatctt gaacagctca ctaaagtgca caaacagttg gtacgtgata atgcagatct
2881 ccgctgtgaa cttcctaagt tggaaaagcg acttcgagct acagctgaga gagtgaaagc
2941 tttggaatca gcactgaaag aagctaaaga aaatgcatct cgtgatcgca aacgctatca
3001 gcaagaagta gatcgcataa aggaagcagt caggtcaaag aatatggcca gaagagggca
3061 ttctgcacag attgctaaac ctattcgtcc cgggcaacat ccagcagctt ctccaactca
3121 cccaagtgca attcgtggag gaggtgcatt tgttcagaac agccagccag tggcagtgcg
3181 aggtggagga ggcaaacaag tgtaatcgtt tatacatacc cacaggtgtt aaaaagtaat
3241 cgaagtacga agaggacatg gtatcaagca gtcattcaat gactataacc tctactccct
3301 tgggattgta gaattataac ttttaaaaaa aatgtataaa ttatacctgg cctgtacagc
3361 tgtttcctac ctactcttct tgtaaactct gctgcttccc aacacaacta gagtgcaatt
3421 ttggcatctt aggagggaaa aaggacagtt tacaactgtg gccctattta ttacacagtt
3481 tgtctatcgt gtcttaaatt tagtctttac tgtgccaagc taactctacc ttataggact
3541 gtactttttg tattttttgt gtatgtttat tttttaatct cagtttaaat tacctagcta
3601 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3661 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//