LOCUS X65858 2245 bp DNA linear HUM 25-JUN-1997
DEFINITION H.sapiens gene for high affinity IL-8 receptor.
ACCESSION X65858
VERSION X65858.1
KEYWORDS G protein-coupled receptor; high affinity interleukin-8 receptor;
interleukin 8 receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 2 (bases 1 to 2245)
AUTHORS Mollereau C., Passage E., Mattei M.G., Vassart G., Parmentier M.
TITLE The high-affinity interleukin 8 receptor gene (IL8RA) maps to the
2q33-q36 region of the human genome: cloning of a pseudogene
(IL8RBP) for the low-affinity receptor
JOURNAL Genomics 16(1), 248-251(1993).
PUBMED 8486366
REFERENCE 3 (bases 1 to 2245)
AUTHORS Parmentier M.
JOURNAL Submitted (27-APR-1992) to the INSDC. M. Parmentier, Universite
Libre de Bruxelles, I.R.I.B.H.N. ULB Campus Erasme, 808 route de
Lennik, 1070 Bruxelles, BELGIUM
FEATURES Location/Qualifiers
source 1..2245
/db_xref="H-InvDB:HIT000398801"
/organism="Homo sapiens"
/chromosome="2"
/map="p33-36"
/mol_type="genomic DNA"
/clone_lib="lambda charon 4a"
/clone="CM5"
/db_xref="taxon:9606"
mRNA 465..2245
CDS 498..1550
/product="High affinity interleukin-8 receptor"
/note="G protein-coupled receptor"
/db_xref="GOA:P25024"
/db_xref="H-InvDB:HIT000398801.8"
/db_xref="HGNC:HGNC:6026"
/db_xref="InterPro:IPR000174"
/db_xref="InterPro:IPR000276"
/db_xref="InterPro:IPR001355"
/db_xref="InterPro:IPR017452"
/db_xref="PDB:1ILP"
/db_xref="PDB:1ILQ"
/db_xref="PDB:2LNL"
/db_xref="UniProtKB/Swiss-Prot:P25024"
/protein_id="CAA46688.1"
/translation="MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVII
AYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNG
WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGC
WGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVM
LFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQES
CERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARH
RVTSYTSSSVNVSSNL"
BASE COUNT 530 a 595 c 569 g 551 t
ORIGIN
1 gggagaaaca tagggaatag aaaataagta agaaggggac acctgggaac aggtttgcct
61 tcttgcattt tgcttaatgc tggcccttcc ctgaatgtct aagaccaacc tggtccccac
121 atccaaatgc acagacacag ctgaggatgg agaaggctaa agagggacag aggtagagac
181 ataggctgag aggaggcagt tgtaggttga gctagggcta aggtgttttc cccatattcc
241 atcttacccc acactcaggc caggccttag agttgtggaa ggtggagaac actgggaagc
301 caacctccga agaagaccag gttggagtca aaggaggaag gagagctctc attgccaaac
361 caacagggaa gccaaggata tcccagtaac tgctctcaca tcattgatga gaatgccttg
421 aatccgagct actaaatcac atttccttcc ttctaacctt ccagttagat caaaccattg
481 ctgaaactga agaggacatg tcaaatatta cagatccaca gatgtgggat tttgatgatc
541 taaatttcac tggcatgcca cctgcagatg aagattacag cccctgtatg ctagaaactg
601 agacactcaa caagtatgtt gtgatcatcg cctatgccct agtgttcctg ctgagcctgc
661 tgggaaactc cctggtgatg ctggtcatct tatacagcag ggtcggccgc tccgtcactg
721 atgtctacct gctgaacctg gccttggccg acctactctt tgccctgacc ttgcccatct
781 gggccgcctc caaggtgaat ggctggattt ttggcacatt cctgtgcaag gtggtctcac
841 tcctgaagga agtcaacttc tacagtggca tcctgctgtt ggcctgcatc agtgtggacc
901 gttacctggc cattgtccat gccacacgca cactgaccca gaagcgtcac ttggtcaagt
961 ttgtttgtct tggctgctgg ggactgtcta tgaatctgtc cctgcccttc ttccttttcc
1021 gccaggctta ccatccaaac aattccagtc cagtttgcta tgaggtcctg ggaaatgaca
1081 cagcaaaatg gcggatggtg ttgcggatcc tgcctcacac ctttggcttc atcgtgccgc
1141 tgtttgtcat gctgttctgc tatggattca ccctgcgtac actgtttaag gcccacatgg
1201 ggcagaagca ccgagccatg agggtcatct ttgctgtcgt cctcatcttc ctgctttgct
1261 ggctgcccta caacctggtc ctgctggcag acaccctcat gaggacccag gtgatccagg
1321 agagctgtga gcgccgcaac aacatcggcc gggccctgga tgccactgag attctgggat
1381 ttctccatag ctgcctcaac cccatcatct acgccttcat cggccaaaat tttcgccatg
1441 gattcctcaa gatcctggct atgcatggcc tggtcagcaa ggagttcttg gcacgtcatc
1501 gtgttacctc ctacacttct tcgtctgtca atgtctcttc caacctctga aaaccatcga
1561 tgaaggaata tctcttctca gaaggaaaga ataaccaaca ccctgaggtt gtgtgtggaa
1621 ggtgatctgg ctctggacag gcactatctg ggttttgggg ggacgctata ggatgtgggg
1681 aagttaggaa ctggtgtctt caggggccac accaaccttc tgaggagctg ttgaggtacc
1741 tccaaggacc ggcctttgca cctccatgga aacgaagcac catcattccc gttgaacgtc
1801 acatctttaa cccactaact ggctaattag catggccaca tctgagcccc gaatctgaca
1861 ttagatgaga gaacagggct gaagctgtgt cctcatgagg gctggatgct ctcgttgacc
1921 ctcacaggag catctcctca actctgagtg ttaagcgttg agccaccaag ctggtggctc
1981 tgtgtgctct gatccgagct caggggggtg gttttcccat ctcaggtgtg ttgcagtgtc
2041 tgctggagac attgaggcag gcactgccaa aacatcaacc tgccagctgg ccttgtgagg
2101 agctggaaac acatgttccc cttgggggtg gtggatgaac aaagagaaag agggtttgga
2161 agccagatct atgccacaag aacccccttt acccccatga ccaacatcgc agacacatgt
2221 gctggccacc tgctgagccc caagt
//