LOCUS X65551 11435 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mki67a mRNA (short type) for antigen of monoclonal
antibody Ki-67.
ACCESSION X65551
VERSION X65551.1
KEYWORDS antigen; monoclonal antibody.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 11435)
AUTHORS Gerdes Fors J.
JOURNAL Submitted (11-APR-1992) to the INSDC. J. Gerdes, Forschungsinstitut
Borstel, Div. Molecular Immunology, Parkallee 22, 2061 Borstel, FRG
REMARK sequence revised by author 14-JUL-93 and 08-OCT-93
REFERENCE 2
AUTHORS Schlueter C., Duchrow M., Wholenberg C., Becker M.H.G., Key G.,
Flad HD., Gerdes J.
TITLE The cell proliferation-associated antigen of antibody Ki-67: a very
large, ubiquitous nuclear protein with numerous repeated elements,
representing a new kind of cell cycle-maintaining proteins.
JOURNAL J. Cell Biol. 123(3), 513-522(1993).
PUBMED 8227122
FEATURES Location/Qualifiers
source 1..11435
/db_xref="H-InvDB:HIT000322748"
/organism="Homo sapiens"
/chromosome="10q25-qter"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/cell_line="IM9"
/db_xref="taxon:9606"
exon 1..107
/number=1
exon 108..288
/number=2
CDS 197..8887
/gene="mki-67"
/product="antigen of the monoclonal antibody Ki-67"
/db_xref="GOA:P46013"
/db_xref="H-InvDB:HIT000322748.14"
/db_xref="HGNC:HGNC:7107"
/db_xref="InterPro:IPR000253"
/db_xref="InterPro:IPR008984"
/db_xref="InterPro:IPR012568"
/db_xref="InterPro:IPR029334"
/db_xref="PDB:1R21"
/db_xref="PDB:2AFF"
/db_xref="PDB:5J28"
/db_xref="UniProtKB/Swiss-Prot:P46013"
/protein_id="CAA46520.1"
/translation="MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVV
SKQHCKIEIHEQEAILHNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESL
QNGRKSTEFPRKIREQEPARRVSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDEN
LPPNTPLKRGEAPTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVI
SPPAPSPRKTPVASDQRRRSCKTAPASSSKSQTEVPKRGGERVATCLQKRVSISRSQH
DILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPAT
PKKPVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPARPYRVLNNFISNQKMDFKEDL
SGIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGEEPLLPTSESFGGNVF
FSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTSLETKTSDTETEPSKT
VSTVNRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIE
RPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQN
LLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVG
KFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLE
DLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEE
EFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKE
KAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIR
KADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRR
PQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQ
PKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASV
TGSKRHPKTKEKAQPLEDLAGWKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTS
SKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDL
TENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDL
DKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESP
KQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYR
ASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDIN
TFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTADEKTT
KKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVG
EEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEES
MTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQT
HRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTP
DHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTT
HTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQ
TPVCTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTP
SVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAG
FKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLAL
RKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEAL
EDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMK
EEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRK
EKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRP
RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRP
RAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHL
RTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTG
SRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKR
RPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRNVDAEDV
IGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPL
KISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRC
MPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKT
NKEEHKLQDSVPENKGISLRSRRQDKTEAEQQITEVFVLAERIEINRNEKKPMKTSPE
MDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKG
KGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIT
TRSHRDSEDI"
exon 289..367
/number=3
exon 368..483
/number=4
exon 484..550
/number=5
exon 561..596
/number=6
exon 597..772
/number=8
/note="exon 7 is partially excluded by splicing"
exon 773..1085
/number=9
exon 1086..1204
/number=10
exon 1205..1385
/number=11
exon 1386..1532
/number=12
exon 1533..8377
/number=13
exon 8378..8821
/number=14
exon 8822..11413
/number=15
regulatory 8914..8919
/regulatory_class="polyA_signal_sequence"
regulatory 9449..9454
/regulatory_class="polyA_signal_sequence"
regulatory 10157..10162
/regulatory_class="polyA_signal_sequence"
regulatory 11388..11393
/regulatory_class="polyA_signal_sequence"
polyA_site 11414
BASE COUNT 3802 a 2828 c 2684 g 2121 t
ORIGIN
1 ctaccgggcg gaggtgagcg cggcgccggc tcctcctgcg gcggactttg ggtgcgactt
61 gacgagcggt ggttcgacaa gtggccttgc gggccggatc gtcccagtgg aagagttgta
121 aatttgcttc tggccttccc ctacggatta tacctggcct tcccctacgg attatactca
181 acttactgtt tagaaaatgt ggcccacgag acgcctggtt actatcaaaa ggagcggggt
241 cgacggtccc cactttcccc tgagcctcag cacctgcttg tttggaaggg gtattgaatg
301 tgacatccgt atccagcttc ctgttgtgtc aaaacaacat tgcaaaattg aaatccatga
361 gcaggaggca atattacata atttcagttc cacaaatcca acacaagtaa atgggtctgt
421 tattgatgag cctgtacggc taaaacatgg agatgtaata actattattg atcgttcctt
481 caggtatgaa aatgaaagtc ttcagaatgg aaggaagtca actgaatttc caagaaaaat
541 acgtgaacag gagccagcac gtcgtgtctc aagatctagc ttctcttctg accctgatga
601 gagtgaggga atacctttga aaagaaggcg tgtgtccttt ggtgggcacc taagacctga
661 actatttgat gaaaacttgc ctcctaatac gcctctcaaa aggggagaag ccccaaccaa
721 aagaaagtct ctggtaatgc acactccacc tgtcctgaag aaaatcatca aggaacagcc
781 tcaaccatca ggaaaacaag agtcaggttc agaaatccat gtggaagtga aggcacaaag
841 cttggttata agccctccag ctcctagtcc taggaaaact ccagttgcca gtgatcaacg
901 ccgtaggtcc tgcaaaacag cccctgcttc cagcagcaaa tctcagacag aggttcctaa
961 gagaggagga gaaagagtgg caacctgcct tcaaaagaga gtgtctatca gccgaagtca
1021 acatgatatt ttacagatga tatgttccaa aagaagaagt ggtgcttcgg aagcaaatct
1081 gattgttgca aaatcatggg cagatgtagt aaaacttggt gcaaaacaaa cacaaactaa
1141 agtcataaaa catggtcctc aaaggtcaat gaacaaaagg caaagaagac ctgctactcc
1201 aaagaagcct gtgggcgaag ttcacagtca atttagtaca ggccacgcaa actctccttg
1261 taccataata atagggaaag ctcatactga aaaagtacat gtgcctgctc gaccctacag
1321 agtgctcaac aacttcattt ccaaccaaaa aatggacttt aaggaagatc tttcaggaat
1381 agctgaaatg ttcaagaccc cagtgaagga gcaaccgcag ttgacaagca catgtcacat
1441 cgctatttca aattcagaga atttgcttgg aaaacagttt caaggaactg attcaggaga
1501 agaacctctg ctccccacct cagagagttt tggaggaaat gtgttcttca gtgcacagaa
1561 tgcagcaaaa cagccatctg ataaatgctc tgcaagccct cccttaagac ggcagtgtat
1621 tagagaaaat ggaaacgtag caaaaacgcc caggaacacc tacaaaatga cttctctgga
1681 gacaaaaact tcagatactg agacagagcc ttcaaaaaca gtatccactg taaacaggtc
1741 aggaaggtct acagagttca ggaatataca gaagctacct gtggaaagta agagtgaaga
1801 aacaaataca gaaattgttg agtgcatcct aaaaagaggt cagaaggcaa cactactaca
1861 acaaaggaga gaaggagaga tgaaggaaat agaaagacct tttgagacat ataaggaaaa
1921 tattgaatta aaagaaaacg atgaaaagat gaaagcaatg aagagatcaa gaacttgggg
1981 gcagaaatgt gcaccaatgt ctgacctgac agacctcaag agcttgcctg atacagaact
2041 catgaaagac acggcacgtg gccagaatct cctccaaacc caagatcatg ccaaggcacc
2101 aaagagtgag aaaggcaaaa tcactaaaat gccctgccag tcattacaac cagaaccaat
2161 aaacacccca acacacacaa aacaacagtt gaaggcatcc ctggggaaag taggtgtgaa
2221 agaagagctc ctagcagtcg gcaagttcac acggacgtca ggggagacca cgcacacgca
2281 cagagagcca gcaggagatg gcaagagcat cagaacgttt aaggagtctc caaagcagat
2341 cctggaccca gcagcccgtg taactggaat gaagaagtgg ccaagaacgc ctaaggaaga
2401 ggcccagtca ctagaagacc tggctggctt caaagagctc ttccagacac caggtccctc
2461 tgaggaatca atgactgatg agaaaactac caaaatagcc tgcaaatctc caccaccaga
2521 atcagtggac actccaacaa gcacaaagca atggcctaag agaagtctca ggaaagcaga
2581 tgtagaggaa gaattcttag cactcaggaa actaacacca tcagcaggga aagccatgct
2641 tacgcccaaa ccagcaggag gtgatgagaa agacattaaa gcatttatgg gaactccagt
2701 gcagaaactg gacctggcag gaactttacc tggcagcaaa agacagctac agactcctaa
2761 ggaaaaggcc caggctctag aagacctggc tggctttaaa gagctcttcc agactcctgg
2821 tcacaccgag gaattagtgg ctgctggtaa aaccactaaa ataccctgcg actctccaca
2881 gtcagaccca gtggacaccc caacaagcac aaagcaacga cccaagagaa gtatcaggaa
2941 agcagatgta gagggagaac tcttagcgtg caggaatcta atgccatcag caggcaaagc
3001 catgcacacg cctaaaccat cagtaggtga agagaaagac atcatcatat ttgtgggaac
3061 tccagtgcag aaactggacc tgacagagaa cttaaccggc agcaagagac ggccacaaac
3121 tcctaaggaa gaggcccagg ctctggaaga cctgactggc tttaaagagc tcttccagac
3181 ccctggtcat actgaagaag cagtggctgc tggcaaaact actaaaatgc cctgcgaatc
3241 ttctccacca gaatcagcag acaccccaac aagcacaaga aggcagccca agacaccttt
3301 ggagaaaagg gacgtacaga aggagctctc agccctgaag aagctcacac agacatcagg
3361 ggaaaccaca cacacagata aagtaccagg aggtgaggat aaaagcatca acgcgtttag
3421 ggaaactgca aaacagaaac tggacccagc agcaagtgta actggtagca agaggcaccc
3481 aaaaactaag gaaaaggccc aacccctaga agacctggct ggctggaaag agctcttcca
3541 gacaccagta tgcactgaca agcccacgac tcacgagaaa actaccaaaa tagcctgcag
3601 atcacaacca gacccagtgg acacaccaac aagctccaag ccacagtcca agagaagtct
3661 caggaaagtg gacgtagaag aagaattctt cgcactcagg aaacgaacac catcagcagg
3721 caaagccatg cacacaccca aaccagcagt aagtggtgag aaaaacatct acgcatttat
3781 gggaactcca gtgcagaaac tggacctgac agagaactta actggcagca agagacggct
3841 acaaactcct aaggaaaagg cccaggctct agaagacctg gctggcttta aagagctctt
3901 ccagacacga ggtcacactg aggaatcaat gactaacgat aaaactgcca aagtagcctg
3961 caaatcttca caaccagacc tagacaaaaa cccagcaagc tccaagcgac ggctcaagac
4021 atccctgggg aaagtgggcg tgaaagaaga gctcctagca gttggcaagc tcacacagac
4081 atcaggagag actacacaca cacacacaga gccaacagga gatggtaaga gcatgaaagc
4141 atttatggag tctccaaagc agatcttaga ctcagcagca agtctaactg gcagcaagag
4201 gcagctgaga actcctaagg gaaagtctga agtccctgaa gacctggccg gcttcatcga
4261 gctcttccag acaccaagtc acactaagga atcaatgact aatgaaaaaa ctaccaaagt
4321 atcctacaga gcttcacagc cagacctagt ggacacccca acaagctcca agccacagcc
4381 caagagaagt ctcaggaaag cagacactga agaagaattt ttagcattta ggaaacaaac
4441 gccatcagca ggcaaagcca tgcacacacc caaaccagca gtaggtgaag agaaagacat
4501 caacacgttt ttgggaactc cagtgcagaa actggaccag ccaggaaatt tacctggcag
4561 caatagacgg ctacaaactc gtaaggaaaa ggcccaggct ctagaagaac tgactggctt
4621 cagagagctt ttccagacac catgcactga taaccccaca gctgatgaga aaactaccaa
4681 aaaaatactc tgcaaatctc cgcaatcaga cccagcggac accccaacaa acacaaagca
4741 acggcccaag agaagcctca agaaagcaga cgtagaggaa gaatttttag cattcaggaa
4801 actaacacca tcagcaggca aagccatgca cacgcctaaa gcagcagtag gtgaagagaa
4861 agacatcaac acatttgtgg ggactccagt ggagaaactg gacctgctag gaaatttacc
4921 tggcagcaag agacggccac aaactcctaa agaaaaggcc aaggctctag aagatctggc
4981 tggcttcaaa gagctcttcc agacaccagg tcacactgag gaatcaatga ccgatgacaa
5041 aatcacagaa gtatcctgca aatctccaca accagaccca gtcaaaaccc caacaagctc
5101 caagcaacga ctcaagatat ccttggggaa agtaggtgtg aaagaagagg tcctaccagt
5161 cggcaagctc acacagacgt cagggaagac cacacagaca cacagagaga cagcaggaga
5221 tggaaagagc atcaaagcgt ttaaggaatc tgcaaagcag atgctggacc cagcaaacta
5281 tggaactggg atggagaggt ggccaagaac acctaaggaa gaggcccaat cactagaaga
5341 cctggccggc ttcaaagagc tcttccagac accagaccac actgaggaat caacaactga
5401 tgacaaaact accaaaatag cctgcaaatc tccaccacca gaatcaatgg acactccaac
5461 aagcacaagg aggcggccca aaacaccttt ggggaaaagg gatatagtgg aagagctctc
5521 agccctgaag cagctcacac agaccacaca cacagacaaa gtaccaggag atgaggataa
5581 aggcatcaac gtgttcaggg aaactgcaaa acagaaactg gacccagcag caagtgtaac
5641 tggtagcaag aggcagccaa gaactcctaa gggaaaagcc caacccctag aagacttggc
5701 tggcttgaaa gagctcttcc agacaccagt atgcactgac aagcccacga ctcacgagaa
5761 aactaccaaa atagcctgca gatctccaca accagaccca gtgggtaccc caacaatctt
5821 caagccacag tccaagagaa gtctcaggaa agcagacgta gaggaagaat ccttagcact
5881 caggaaacga acaccatcag tagggaaagc tatggacaca cccaaaccag caggaggtga
5941 tgagaaagac atgaaagcat ttatgggaac tccagtgcag aaattggacc tgccaggaaa
6001 tttacctggc agcaaaagat ggccacaaac tcctaaggaa aaggcccagg ctctagaaga
6061 cctggctggc ttcaaagagc tcttccagac accaggcact gacaagccca cgactgatga
6121 gaaaactacc aaaatagcct gcaaatctcc acaaccagac ccagtggaca ccccagcaag
6181 cacaaagcaa cggcccaaga gaaacctcag gaaagcagac gtagaggaag aatttttagc
6241 actcaggaaa cgaacaccat cagcaggcaa agccatggac accccaaaac cagcagtaag
6301 tgatgagaaa aatatcaaca catttgtgga aactccagtg cagaaactgg acctgctagg
6361 aaatttacct ggcagcaaga gacagccaca gactcctaag gaaaaggctg aggctctaga
6421 ggacctggtt ggcttcaaag aactcttcca gacaccaggt cacactgagg aatcaatgac
6481 tgatgacaaa atcacagaag tatcctgtaa atctccacag ccagagtcat tcaaaacctc
6541 aagaagctcc aagcaaaggc tcaagatacc cctggtgaaa gtggacatga aagaagagcc
6601 cctagcagtc agcaagctca cacggacatc aggggagact acgcaaacac acacagagcc
6661 aacaggagat agtaagagca tcaaagcgtt taaggagtct ccaaagcaga tcctggaccc
6721 agcagcaagt gtaactggta gcaggaggca gctgagaact cgtaaggaaa aggcccgtgc
6781 tctagaagac ctggttgact tcaaagagct cttctcagca ccaggtcaca ctgaagagtc
6841 aatgactatt gacaaaaaca caaaaattcc ctgcaaatct cccccaccag aactaacaga
6901 cactgccacg agcacaaaga gatgccccaa gacacgtccc aggaaagaag taaaagagga
6961 gctctcagca gttgagaggc tcacgcaaac atcagggcaa agcacacaca cacacaaaga
7021 accagcaagc ggtgatgagg gcatcaaagt attgaagcaa cgtgcaaaga agaaaccaaa
7081 cccagtagaa gaggaaccca gcaggagaag gccaagagca cctaaggaaa aggcccaacc
7141 cctggaagac ctggccggct tcacagagct ctctgaaaca tcaggtcaca ctcaggaatc
7201 actgactgct ggcaaagcca ctaaaatacc ctgcgaatct cccccactag aagtggtaga
7261 caccacagca agcacaaaga ggcatctcag gacacgtgtg cagaaggtac aagtaaaaga
7321 agagccttca gcagtcaagt tcacacaaac atcaggggaa accacggatg cagacaaaga
7381 accagcaggt gaagataaag gcatcaaagc attgaaggaa tctgcaaaac agacaccggc
7441 tccagcagca agtgtaactg gcagcaggag acggccaaga gcacccaggg aaagtgccca
7501 agccatagaa gacctagctg gcttcaaaga cccagcagca ggtcacactg aagaatcaat
7561 gactgatgac aaaaccacta aaataccctg caaatcatca ccagaactag aagacaccgc
7621 aacaagctca aagagacggc ccaggacacg tgcccagaaa gtagaagtga aggaggagct
7681 gttagcagtt ggcaagctca cacaaacctc aggggagacc acgcacaccg acaaagagcc
7741 ggtaggtgag ggcaaaggca cgaaagcatt taagcaacct gcaaagcgga acgtggacgc
7801 agaagatgta attggcagca ggagacagcc aagagcacct aaggaaaagg cccaacccct
7861 ggaagacctg gccagcttcc aagagctctc tcaaacacca ggccacactg aggaactggc
7921 aaatggtgct gctgatagct ttacaagcgc tccaaagcaa acacctgaca gtggaaaacc
7981 tctaaaaata tccagaagag ttcttcgggc ccctaaagta gaacccgtgg gagacgtggt
8041 aagcaccaga gaccctgtaa aatcacaaag caaaagcaac acttccctgc ccccactgcc
8101 cttcaagagg ggaggtggca aagatggaag cgtcacggga accaagaggc tgcgctgcat
8161 gccagcacca gaggaaattg tggaggagct gccagccagc aagaagcaga gggttgctcc
8221 cagggcaaga ggcaaatcat ccgaacccgt ggtcatcatg aagagaagtt tgaggacttc
8281 tgcaaaaaga attgaacctg cggaagagct gaacagcaac gacatgaaaa ccaacaaaga
8341 ggaacacaaa ttacaagact cggtccctga aaataaggga atatccctgc gctccagacg
8401 ccaagataag actgaggcag aacagcaaat aactgaggtc tttgtattag cagaaagaat
8461 agaaataaac agaaatgaaa agaagcccat gaagacctcc ccagagatgg acattcagaa
8521 tccagatgat ggagcccgga aacccatacc tagagacaaa gtcactgaga acaaaaggtg
8581 cttgaggtct gctagacaga atgagagctc ccagcctaag gtggcagagg agagcggagg
8641 gcagaagagt gcgaaggttc tcatgcagaa tcagaaaggg aaaggagaag caggaaattc
8701 agactccatg tgcctgagat caagaaagac aaaaagccag cctgcagcaa gcactttgga
8761 gagcaaatct gtgcagagag taacgcggag tgtcaagagg tgtgcagaaa atccaaagaa
8821 ggctgaggac aatgtgtgtg tcaagaaaat aacaaccaga agtcataggg acagtgaaga
8881 tatttgacag aaaaatcgaa ctgggaaaaa tataataaag ttagttttgt gataagttct
8941 agtgcagttt ttgtcataaa ttacaagtga attctgtaag taaggctgtc agtctgctta
9001 agggaagaaa actttggatt tgctgggtct gaatcggctt cataaactcc actgggagca
9061 ctgctgggct cctggactga gaatagttga acaccggggg ctttgtgaag gagtctgggc
9121 caaggtttgc cctcagcttt gcagaatgaa gccttgaggt ctgtcaccac ccacagccac
9181 cctacagcag ccttaactgt gacacttgcc acactgtgtc gtcgtttgtt tgcctatgtt
9241 ctccagggca cggtggcagg aacaactatc ctcgtctgtc ccaacactga gcaggcactc
9301 ggtaaacacg aatgaatgga taagcgcacg gatgaatgga gcttacaaga tctgtctttc
9361 caatggccgg gggcatttgg tccccaaatt aaggctattg gacatctgca caggacagtc
9421 ctatttttga tgtcctttcc tttctgaaaa taaagttttg tgctttggag aatgactcgt
9481 gagcacatct ttagggacca agagtgactt tctgtaagga gtgactcgtg gcttgccttg
9541 gtctcttggg aatacttttc taactagggt tgctctcacc tgagacattc tccacccgcg
9601 gaatctcagg gtcccaggct gtgggccatc acgacctcaa actggctcct aatctccagc
9661 tttcctgtca ttgaaagctt cggaagttta ctggctctgc tcccgcctgt tttctttctg
9721 actctatctg gcagcccgat gccacccagt acaggaagtg acaccagtac tctgtaaagc
9781 atcatcatcc ttggagagac tgagcactca gcaccttcag ccacgatttc aggatcgctt
9841 ccttgtgagc cgctgcctcc gaaatctcct ttgaagccca gacatctttc tccagcttca
9901 gacttgtaga tataactcgt tcatcttcat ttactttcca ctttgccccc tgtcctctct
9961 gtgttcccca aatcagagaa tagcccgcca tcccccagat cacctgtctg gattcctccc
10021 cattcaccca ccttgccagg tgcaggtgag gatggtgcac cagacagggt agctgtcccc
10081 caaaatgtgc cctgtgcggg cagtgccctg tctccacgtt tgtttcccca gtgtctggcg
10141 gggagccagg tgacatcata aatacttgct gaatgaatgc agaaatcagc ggtactgact
10201 tgtactatat tggctgccat gatagggttc tcacagcgtc atccatgatc gtaagggaga
10261 atgacattct gcttgaggga gggaatagaa aggggcaggg aggggacatc tgagggcttc
10321 acagggctgc aaagggtaca gggattgcac cagggcagaa caggggaggg tgttcaagga
10381 agagtggctc ttagcagagg cactttggaa ggtgtgaggc ataaatgctt ccttctacgt
10441 aggccaacct caaaactttc agtaggaatg ttgctatgat caagttgttc taacacttta
10501 gacttagtag taattatgaa cctcacatag aaaaatttca tccagccata tgcctgtgga
10561 gtggaatatt ctgtttagta gaaaaatcct ttagagttca gctctaacca gaaatcttgc
10621 tgaagtatgt cagcaccttt tctcaccctg gtaagtacag tatttcaaga gcacgctaag
10681 ggtggttttc attttacagg gctgttgatg atgggttaaa aatgttcatt taagggctac
10741 ccccgtgttt aatagatgaa caccacttct acacaaccct ccttggtact gggggaggga
10801 gagatctgac aaatactgcc cattccccta ggctgactgg atttgagaac aaatacccac
10861 ccatttccac catggtatgg taacttctct gagcttcagt ttccaagtga atttccatgt
10921 aataggacat tcccattaaa tacaagctgt ttttactttt tcgcctccca gggcctgtgc
10981 gatctggtcc cccagcctct cttgggcttt cttacactaa ctctgtacct accatctcct
11041 gcctccctta ggcaggcacc tccaaccacc acacactccc tgctgttttc cctgcctgga
11101 actttcccac cagccccacc aagatcattt catccagtcc tgagctcagc ttaagggagg
11161 cttcttgcct gtgggttccc tcacccccat gcctgtcctc caggctgggg caggttctta
11221 gtttgcctgg aattgttctg tacctctttg tagcacgtag tgttgtgaaa ctaagccact
11281 aattgagttt ctggctcccc tcctggggtt gtaagttttg ttcattcatg agggccgact
11341 gtatttcctg gttactgtat cccagtgacc agccacagga gatgtccaat aaagtatgtg
11401 atgaaatggt cttaaaaaaa aaaaaaaaaa aaaaa
//