LOCUS X65372 3209 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens PTB-4 gene for polypirimidine tract binding protein.
ACCESSION X65372
VERSION X65372.1
KEYWORDS binding protein; polypirimidine tract binding protein; PTB gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3209)
AUTHORS Patton J.G.
JOURNAL Submitted (04-MAY-1992) to the INSDC. J.G. Patton, Harvard Medical
School and, Children's Hospital/Dept of Cardiology, 300 Longwood
Ave, Boston MA 02115, USA
REFERENCE 2 (bases 1 to 3209)
AUTHORS Patton J.G., Mayer S.A., Nadal-Ginard B.
TITLE Characterization and molecular cloning of polypyrimidine
tract-binding protein: a component of a complex necessary for
pre-mRNA splicing
JOURNAL Genes Dev. 5(7), 1237-1251(1991).
PUBMED 1906036
COMMENT See also X63571-2, X62006, X60648 & X52101.
FEATURES Location/Qualifiers
source 1..3209
/db_xref="H-InvDB:HIT000322743"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="gt-10"
/cell_line="HeLa cells"
/db_xref="taxon:9606"
CDS 46..1719
/gene="PTB-4"
/product="polypirimidine tract binding protein"
/db_xref="GOA:P26599"
/db_xref="H-InvDB:HIT000322743.13"
/db_xref="HGNC:HGNC:9583"
/db_xref="InterPro:IPR000504"
/db_xref="InterPro:IPR006536"
/db_xref="InterPro:IPR012677"
/db_xref="InterPro:IPR021790"
/db_xref="InterPro:IPR034798"
/db_xref="InterPro:IPR035000"
/db_xref="InterPro:IPR035001"
/db_xref="InterPro:IPR035979"
/db_xref="PDB:1QM9"
/db_xref="PDB:1SJQ"
/db_xref="PDB:1SJR"
/db_xref="PDB:2AD9"
/db_xref="PDB:2ADB"
/db_xref="PDB:2ADC"
/db_xref="PDB:2EVZ"
/db_xref="PDB:2N3O"
/db_xref="PDB:3ZZY"
/db_xref="PDB:3ZZZ"
/db_xref="UniProtKB/Swiss-Prot:P26599"
/protein_id="CAA46444.1"
/translation="MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDS
KKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMN
TEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSG
NLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTK
NNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT
RPDLPSGDSQPSLDQTMAAAFGAPGIISASPYAGAGFPPTFAIPQAAGLSVPNVHGAL
APLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQR
VKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQ
GLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVK
GFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI"
BASE COUNT 685 a 993 c 843 g 688 t
ORIGIN
1 attccggcgg ctccactccg tcccccgcgg tctgctctgt gtgccatgga cggcatcgtc
61 ccagatatag ccgttggtac aaagcgggga tctgacgagc ttttctctac ttgtgtcact
121 aacggaccgt ttatcatgag cagcaactcg gcttctgcag caaacggaaa tgacagcaag
181 aagttcaaag gtgacagccg aagtgcaggc gtcccctcta gagtgatcca catccggaag
241 ctccccatcg acgtcacgga gggggaagtc atctccctgg ggctgccctt tgggaaggtc
301 accaacctcc tgatgctgaa ggggaaaaac caggccttca tcgagatgaa cacggaggag
361 gctgccaaca ccatggtgaa ctactacacc tcggtgaccc ctgtgctgcg cggccagccc
421 atctacatcc agttctctaa ccacaaggag ctgaagaccg acagctctcc caaccaggcg
481 cgggcccagg cggccctgca ggcggtgaac tcggtccagt cggggaacct ggccttggct
541 gcctcggcgg cggccgtgga cgcagggatg gcgatggccg ggcagagccc tgtgctcagg
601 atcatcgtgg agaacctctt ctaccctgtg accctggatg tgctgcacca gattttctcc
661 aagttcggca cagtgttgaa gatcatcacc ttcaccaaga acaaccagtt ccaggccctg
721 ctgcagtatg cggaccccgt gagcgcccag cacgccaagc tgtcgctgga cgggcagaac
781 atctacaacg cctgctgcac gctgcgcatc gacttttcca agctcaccag cctcaacgtc
841 aagtacaaca atgacaagag ccgtgactac acacgcccag acctgccttc cggggacagc
901 cagccctcgc tggaccagac catggccgcg gccttcggtg cacctggtat aatctcagcc
961 tctccgtatg caggagctgg tttccctccc acctttgcca ttcctcaagc tgcaggcctt
1021 tccgttccga acgtccacgg cgccctggcc cccctggcca tcccctcggc ggcggcggca
1081 gctgcggcgg caggtcggat cgccatcccg ggcctggcgg gggcaggaaa ttctgtattg
1141 ctggtcagca acctcaaccc agagagagtc acaccccaaa gcctctttat tcttttcggc
1201 gtctacggtg acgtgcagcg cgtgaagatc ctgttcaata agaaggagaa cgccctagtg
1261 cagatggcgg acggcaacca ggcccagctg gccatgagcc acctgaacgg gcacaagctg
1321 cacgggaagc cgatccgcat cacgctctcg aagcaccaga acgtgcagct gccccgcgag
1381 ggccaggagg accagggcct gaccaaggac tacggcaact cacccctgca ccgcttcaag
1441 aagccgggct ccaagaactt ccagaacata ttcccgccct cggccactct gcacctctcc
1501 aacatcccgc cctcagtctc cgaggaggat ctcaaggtcc tgttttccag caatgggggc
1561 gtcgtcaaag gattcaagtt cttccagaag gaccgcaaga tggcactgat ccagatgggc
1621 tccgtggagg aggcggtcca ggccctcatt gacctgcaca accacgacct cggggagaac
1681 caccacctgc gggtctcctt ctccaagtcc accatctagg ggcacaggcc cccacggccg
1741 ggccccctgg cgacaacttc catcattcca gagaaaagcc actttaaaaa cagctgaagt
1801 gaccttagca gaccagagat tttatttttt taaagagaaa tcagtttacc tgtttttaaa
1861 aaaattaaat ctagttcacc ttgctcaccc tgcggtgaca gggacagctc aggctcttgg
1921 tgactgtggc agcgggagtt cccggccctc cacacccggg gccagaccct cggggccatg
1981 ccttggtggg gcctgtgtcg ggcgtggggc ctgcaggtgg gcgccccgac cacgacttgg
2041 cttccttgtg ccttaaaaaa cctgcctttc ctgcagccac acacccaccc ggggtgtcct
2101 ggggacccaa ggggtggggg ggtcacacca gagagaggca gggggcctgg ccggctcctg
2161 caggatcatg cagctggggc gcggcggccg cgctgcgagc accccaaccc cagccctcta
2221 atcaagtcac gtgattctcc cttcaccccg cccccagggc cttcccttcc ttgcccccag
2281 gcgggctccc cgctgctcca gctgcggact ggtcgacata atctctgtat tatatacttt
2341 gcagttgcag acgtctgtgc ctagcaatat ttccagttga ccaaatattc taatcttttt
2401 tcatttatat gcaaaagaaa tagttttaag taacttttta tagcaagatg atacaatggt
2461 atgagtgtaa tctaaacttc cttgtggtat taccttgtat gctgttactt ttattttatt
2521 ccttgtaatt aagtcacagg caggacccag tttccagaga gcaggcgggg ccgcccagtg
2581 ggtcaggcac agggagcccc ggtcctatct tagagcccct gagcttcagg gaagggcggc
2641 gtgtcgcgcc tctggcatcg ctccggttgc cttacaccac gccttcacct gcagtcgcct
2701 agaaaacttg ctctcaaact tcagggtttt ttcttcttca aatttggacc aaagtctcat
2761 ttctgtgttt tgcctgcctc tgatgctggg acccggaaag cgggcgctcc tgtctttgtg
2821 ctctttctac cgcccccgcg tcctgtcccg ggggctctcc taggatcccc tttccgtaaa
2881 agcgtgtaac aagggtgtaa atatttataa ttttttatac ctgttgtgag acccgagggg
2941 cggcggcgcg gttttttatg gtgacacaaa tgtatatttt gctaacagca attccaggct
3001 cagtattgtg accgcggagc cacaggggac cccacgcaca ttccgtgcct tacccgatgg
3061 cttgtgacgc ggagagaacc gattaaaacc gtttgagaaa ctcctccctt gtctagccct
3121 gtgttcgctg tggacgctgt agacacaggt tggccagtct gtacctggac ttcgaataaa
3181 tcttctgtat cctcaaaaaa aaaaaaaaa
//