LOCUS X65371 3188 bp mRNA linear HUM 28-MAY-1992
DEFINITION H.sapiens PTB-2 gene for polypirimidine tract binding protein.
ACCESSION X65371
VERSION X65371.1
KEYWORDS binding protein; polypirimidine tract binding protein; PTB gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3188)
AUTHORS Patton J.G.
JOURNAL Submitted (04-MAY-1992) to the INSDC. J.G. Patton, Harvard Medical
School and, Children's Hospital/Dept of Cardiology, 300 Longwood
Ave, Boston MA 02115, USA
REFERENCE 2 (bases 1 to 3188)
AUTHORS Patton J.G., Mayer S.A., Nadal-Ginard B.
TITLE Characterization and molecular cloning of polypyrimidine
tract-binding protein: a component of a complex necessary for
pre-mRNA splicing
JOURNAL Genes Dev. 5(7), 1237-1251(1991).
PUBMED 1906036
COMMENT See also X63571-2, X62006, X60648 & X52101.
FEATURES Location/Qualifiers
source 1..3188
/db_xref="H-InvDB:HIT000322742"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="gt-10"
/cell_line="HeLa cells"
/db_xref="taxon:9606"
CDS 46..1698
/gene="PTB-2"
/product="polypirimidine tract binding protein"
/db_xref="GOA:P26599"
/db_xref="H-InvDB:HIT000322742.13"
/db_xref="HGNC:HGNC:9583"
/db_xref="InterPro:IPR000504"
/db_xref="InterPro:IPR006536"
/db_xref="InterPro:IPR012677"
/db_xref="InterPro:IPR021790"
/db_xref="InterPro:IPR034798"
/db_xref="InterPro:IPR035000"
/db_xref="InterPro:IPR035001"
/db_xref="InterPro:IPR035979"
/db_xref="PDB:1QM9"
/db_xref="PDB:1SJQ"
/db_xref="PDB:1SJR"
/db_xref="PDB:2AD9"
/db_xref="PDB:2ADB"
/db_xref="PDB:2ADC"
/db_xref="PDB:2EVZ"
/db_xref="PDB:2N3O"
/db_xref="PDB:3ZZY"
/db_xref="PDB:3ZZZ"
/db_xref="UniProtKB/Swiss-Prot:P26599"
/protein_id="CAA46443.1"
/translation="MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDS
KKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMN
TEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSG
NLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTK
NNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT
RPDLPSGDSQPSLDQTMAAAFASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPS
AAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNK
KENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYG
NSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQK
DRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI"
BASE COUNT 680 a 988 c 838 g 682 t
ORIGIN
1 attccggcgg ctccactccg tcccccgcgg tctgctctgt gtgccatgga cggcatcgtc
61 ccagatatag ccgttggtac aaagcgggga tctgacgagc ttttctctac ttgtgtcact
121 aacggaccgt ttatcatgag cagcaactcg gcttctgcag caaacggaaa tgacagcaag
181 aagttcaaag gtgacagccg aagtgcaggc gtcccctcta gagtgatcca catccggaag
241 ctccccatcg acgtcacgga gggggaagtc atctccctgg ggctgccctt tgggaaggtc
301 accaacctcc tgatgctgaa ggggaaaaac caggccttca tcgagatgaa cacggaggag
361 gctgccaaca ccatggtgaa ctactacacc tcggtgaccc ctgtgctgcg cggccagccc
421 atctacatcc agttctctaa ccacaaggag ctgaagaccg acagctctcc caaccaggcg
481 cgggcccagg cggccctgca ggcggtgaac tcggtccagt cggggaacct ggccttggct
541 gcctcggcgg cggccgtgga cgcagggatg gcgatggccg ggcagagccc tgtgctcagg
601 atcatcgtgg agaacctctt ctaccctgtg accctggatg tgctgcacca gattttctcc
661 aagttcggca cagtgttgaa gatcatcacc ttcaccaaga acaaccagtt ccaggccctg
721 ctgcagtatg cggaccccgt gagcgcccag cacgccaagc tgtcgctgga cgggcagaac
781 atctacaacg cctgctgcac gctgcgcatc gacttttcca agctcaccag cctcaacgtc
841 aagtacaaca atgacaagag ccgtgactac acacgcccag acctgccttc cggggacagc
901 cagccctcgc tggaccagac catggccgcg gccttcgcct ctccgtatgc aggagctggt
961 ttccctccca cctttgccat tcctcaagct gcaggccttt ccgttccgaa cgtccacggc
1021 gccctggccc ccctggccat cccctcggcg gcggcggcag ctgcggcggc aggtcggatc
1081 gccatcccgg gcctggcggg ggcaggaaat tctgtattgc tggtcagcaa cctcaaccca
1141 gagagagtca caccccaaag cctctttatt cttttcggcg tctacggtga cgtgcagcgc
1201 gtgaagatcc tgttcaataa gaaggagaac gccctagtgc agatggcgga cggcaaccag
1261 gcccagctgg ccatgagcca cctgaacggg cacaagctgc acgggaagcc gatccgcatc
1321 acgctctcga agcaccagaa cgtgcagctg ccccgcgagg gccaggagga ccagggcctg
1381 accaaggact acggcaactc acccctgcac cgcttcaaga agccgggctc caagaacttc
1441 cagaacatat tcccgccctc ggccactctg cacctctcca acatcccgcc ctcagtctcc
1501 gaggaggatc tcaaggtcct gttttccagc aatgggggcg tcgtcaaagg attcaagttc
1561 ttccagaagg accgcaagat ggcactgatc cagatgggct ccgtggagga ggcggtccag
1621 gccctcattg acctgcacaa ccacgacctc ggggagaacc accacctgcg ggtctccttc
1681 tccaagtcca ccatctaggg gcacaggccc ccacggccgg gccccctggc gacaacttcc
1741 atcattccag agaaaagcca ctttaaaaac agctgaagtg accttagcag accagagatt
1801 ttattttttt aaagagaaat cagtttacct gtttttaaaa aaattaaatc tagttcacct
1861 tgctcaccct gcggtgacag ggacagctca ggctcttggt gactgtggca gcgggagttc
1921 ccggccctcc acacccgggg ccagaccctc ggggccatgc cttggtgggg cctgtgtcgg
1981 gcgtggggcc tgcaggtggg cgccccgacc acgacttggc ttccttgtgc cttaaaaaac
2041 ctgcctttcc tgcagccaca cacccacccg gggtgtcctg gggacccaag gggtgggggg
2101 gtcacaccag agagaggcag ggggcctggc cggctcctgc aggatcatgc agctggggcg
2161 cggcggccgc gctgcgagca ccccaacccc agccctctaa tcaagtcacg tgattctccc
2221 ttcaccccgc ccccagggcc ttcccttcct tgcccccagg cgggctcccc gctgctccag
2281 ctgcggactg gtcgacataa tctctgtatt atatactttg cagttgcaga cgtctgtgcc
2341 tagcaatatt tccagttgac caaatattct aatctttttt catttatatg caaaagaaat
2401 agttttaagt aactttttat agcaagatga tacaatggta tgagtgtaat ctaaacttcc
2461 ttgtggtatt accttgtatg ctgttacttt tattttattc cttgtaatta agtcacaggc
2521 aggacccagt ttccagagag caggcggggc cgcccagtgg gtcaggcaca gggagccccg
2581 gtcctatctt agagcccctg agcttcaggg aagggcggcg tgtcgcgcct ctggcatcgc
2641 tccggttgcc ttacaccacg ccttcacctg cagtcgccta gaaaacttgc tctcaaactt
2701 cagggttttt tcttcttcaa atttggacca aagtctcatt tctgtgtttt gcctgcctct
2761 gatgctggga cccggaaagc gggcgctcct gtctttgtgc tctttctacc gcccccgcgt
2821 cctgtcccgg gggctctcct aggatcccct ttccgtaaaa gcgtgtaaca agggtgtaaa
2881 tatttataat tttttatacc tgttgtgaga cccgaggggc ggcggcgcgg ttttttatgg
2941 tgacacaaat gtatattttg ctaacagcaa ttccaggctc agtattgtga ccgcggagcc
3001 acaggggacc ccacgcacat tccgtgcctt acccgatggc ttgtgacgcg gagagaaccg
3061 attaaaaccg tttgagaaac tcctcccttg tctagccctg tgttcgctgt ggacgctgta
3121 gacacaggtt ggccagtctg tacctggact tcgaataaat cttctgtatc ctcaaaaaaa
3181 aaaaaaaa
//