LOCUS       X64168                   324 bp    mRNA    linear   HUM 26-JUL-1997
DEFINITION  H.sapiens mRNA for RegAL kappa light chain variable Ig domain.
ACCESSION   X64168
VERSION     X64168.1
KEYWORDS    Ig kappa light chain; Ig light chain; immunoglobulin light chain
            variable region; light chain; variable region.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Hughes-Jones N.C.
  JOURNAL   Submitted (08-JAN-1992) to the INSDC. N.C. Hughes-Jones, Inst of
            Animal Physiology and Genetics Research, Babraham Hall, Cambridge
            CB2 4AT, UK
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Bye J.M., Carter C., Cui Y., Gorick B.D., Songsivilai S.,
            Winter G., Hughes-Jones N.C., Marks J.D.
  TITLE     Germline variable region gene segment derivation of human
            monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation
            by somatic hypermutation and repertoire shift
  JOURNAL   J. Clin. Invest. 90(6), 2481-2490(1992).
   PUBMED   1469099
COMMENT     See also X64148-69
FEATURES             Location/Qualifiers
     source          1..324
                     /db_xref="H-InvDB:HIT000322667"
                     /organism="Homo sapiens"
                     /chromosome="2"
                     /isolate="blood donor Re"
                     /mol_type="mRNA"
                     /cell_line="Reg-A"
                     /cell_type="B-lymphocytes"
                     /db_xref="taxon:9606"
     misc_feature    1..23
                     /note="PCR primer"
     misc_feature    1..324
                     /note="VJ region"
     misc_feature    1..285
                     /note="V kappa region"
     misc_feature    70..105
                     /note="CDR1 region"
     misc_feature    151..171
                     /note="CDR2 region"
     misc_feature    268..291
                     /note="CDR3 region"
     misc_feature    286..324
                     /note="J region"
BASE COUNT           72 a           94 c           85 g           70 t
ORIGIN      
        1 gawrttcagc tgackcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc
       61 ctctcctgca gggccagtca gagtatgagc agcaactact tagcctggta ccagcagaaa
      121 cctggccagg ctcccagggt cctcatctat ggtgcatcca gcagggccac tggcatccca
      181 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag cagactggag
      241 cctgaagatt ctgcagtgta ttactgtcag cagtttggtg gctcattcac tttcggccct
      301 gggaccacag tggatatcaa acga
//