LOCUS X63359 2799 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens UGT2BIO mRNA for udp glucuronosyltransferase.
ACCESSION X63359
VERSION X63359.1
KEYWORDS UDP-glucuronosyltransferase; ugt2bio gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2799)
AUTHORS Mackenzie P.I.
JOURNAL Submitted (19-NOV-1991) to the INSDC. P.I. Mackenzie, Flinders
University, Dept of Clinical Pharmacology, School of Medicine,
Flinders Medical Centre, Bedford Park SA 5042, AUSTRALIA
REFERENCE 2
AUTHORS Jin C.J., Miners J.O., Lillywhite K.J., Mackenzie P.I.
TITLE cDNA cloning and expression of two new members of the human liver
UDP-glucuronosyltransferase 2B subfamily
JOURNAL Biochem. Biophys. Res. Commun. 194(1), 496-503(1993).
PUBMED 8333863
FEATURES Location/Qualifiers
source 1..2799
/organism="Homo sapiens"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="lambda gt11"
/clone="UGTh-46"
/tissue_type="liver"
/db_xref="taxon:9606"
CDS 11..1597
/gene="UGT2 BIO"
/product="UDP-glucuronosyltransferase"
/EC_number="2.4.1.17"
/db_xref="GOA:P36537"
/db_xref="HGNC:HGNC:12544"
/db_xref="InterPro:IPR002213"
/db_xref="InterPro:IPR035595"
/db_xref="UniProtKB/Swiss-Prot:P36537"
/protein_id="CAA44961.1"
/translation="MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKE
LVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKD
TFWLPFSQEQEILWAINDIIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLA
ELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLY
FDFWFQIFNMKKWDQFYSEVLGRPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFV
GGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNMTEERANVIATALAKIPQKV
LWRFDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGI
PLFFDQPDNIAHMKAKGAAVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHD
QPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWFQYHSLDVIGFLLACVATVLFIIT
KCCLFCFWKFARKGKKGKRD"
regulatory 2772..2788
/regulatory_class="polyA_signal_sequence"
BASE COUNT 792 a 605 c 569 g 833 t
ORIGIN
1 ctgcacaagg atggctctga aatggactac agttctgctg atacaactca gtttttactt
61 tagctctggg agttgtggaa aggtgctggt atgggccgca gaatacagcc tttggatgaa
121 tatgaagaca atcctgaaag aacttgttca gagaggtcat gaggtgactg tactggcatc
181 ttcagcttcc attctttttg atcccaacga ctcatccact cttaaacttg aagtttatcc
241 tacatcttta actaaaactg aatttgagaa tatcatcatg caattggtta agagattgtc
301 agaaattcaa aaagatacat tttggttacc tttttcacaa gaacaagaaa tcctgtgggc
361 aattaatgac ataattagaa acttctgtaa agatgtagtt tcaaataaga aacttatgaa
421 aaaactacaa gagtcaagat ttgacatcgt ttttgcagat gcttatttac cctgtggtga
481 gctgctggct gagctattta acataccctt tgtgtacagt cacagcttca gtcctggcta
541 ctcatttgaa aggcacagtg gaggatttat tttccctcct tcctacgtac ctgttgttat
601 gtcaaaatta agtgatcaaa tgactttcat ggagagggta aaaaatatgc tctatgtgct
661 ttattttgac ttttggttcc aaatatttaa tatgaagaag tgggatcagt tttacagtga
721 agttttagga agacccacta cattatctga gacaatgagg aaagctgaca tatggcttat
781 gcgaaactcc tggaatttta aatttcctca tccattctta ccaaatgttg attttgttgg
841 aggactccac tgcaaacctg ccaaacccct acctaaggaa atggaggagt ttgtacagag
901 ctctggagaa aatggtgttg tggtgttttc tctggggtca atggtcagta acatgacaga
961 agaaagggcc aacgtaattg caacagccct tgccaagatc ccacaaaagg ttctttggag
1021 atttgatggg aataaaccag atgccttagg tctcaatact cgactgtaca agtggatacc
1081 ccagaatgac cttctaggtc atccaaaaac cagagctttt ataactcatg gtggagccaa
1141 tggcatctat gaggcaatct accatgggat ccctatggtg ggcattccat tgttttttga
1201 tcaacctgat aatattgctc acatgaaggc caagggagca gctgttagag tggacttcaa
1261 cacaatgtcg agtacagacc tgctgaatgc actgaagaca gtaattaatg atccttcata
1321 taaagagaat attatgaaat tatcaagaat tcaacatgat caaccagtga agcccctgga
1381 tcgagcagtc ttctggattg aatttgtcat gcgccacaaa ggagccaaac atcttcgagt
1441 tgcagcccac aacctcacct ggttccagta ccactctttg gatgtgattg ggttcctgct
1501 ggcttgtgtg gcaaccgtgc tatttatcat cacaaagtgt tgtctgtttt gtttctggaa
1561 gtttgctaga aaaggaaaga agggaaaaag ggattagtta tatctgagat ttgaagctgg
1621 ggaattccgt ttattgaaga ttcaggttaa cctgaatcaa gttaacccag tctcaaatgc
1681 tcacttatcc tatctccttg gcacaaatct ctcctctcct ggattgccaa agaaaattca
1741 aattattctt caattagtca ggatgatttg actatcagca gttcatagta cccatcttca
1801 taactaagcc acctagggat ccggcagaaa aaaaagggat gcaggggagt catcatacag
1861 ggggtggatc atttaccagg atccacactt cctacaaagc ggttgtaata ttaaataaca
1921 aaactgtttt ttattccaat cttcacataa aacaggaata attgtatact ttcttactaa
1981 tgtgttccat ggagtttttc ctccaagaag tggcttaggg gaaaatgagc cccagtaatg
2041 ctctgtggca tccaatcctt ctaccccgac cctttgactt tctgccccag cccctcttag
2101 ttctcctaga attaggacta aggttaagtg ccctcttggg atatgacttc cttcccttcc
2161 tcttgataca aaaagagcct attaccaacc ctcatacaca caagagttcc cttcctagtt
2221 gcagactctt ctgctccagc tggactcccc tagctctgga ctcccactag atcacacagg
2281 ggtccctgca tgtcagtaaa ctttggatga ccttgggaga ccaaaaaatg gaatatcatt
2341 ttttgatcta aacaaaatag tttcctgatt taacactggc caggaaggtg ggctgcaccc
2401 tcagtctctc tctcccatca tggttttcac atgatatcaa aggactctca taacagtctg
2461 attcttatga gttgggcatc ctgtgtttcc ctttagggcc tgcttccttc aaatagagga
2521 gatgggtgct atgaaaccta ttcactctgg acttgggatg gctcttctcc atcttcccaa
2581 gtctgagctg gagcctccat gcccaactct gctctgctct tctatttcct gacagcagct
2641 aaggcatgtt cctgttctgc ccccaaattg accttactaa cagtgagaac ttggaggagt
2701 cttcgggtct tgggaaatcc aagttttccc ggaaacgttt tgttgtaaac agtgtccaca
2761 ctctttgctc caataaagct cggttcctta agggaattc
//