LOCUS X62006 3131 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens PTB-1 gene for polypirimidine tract binding protein.
ACCESSION X62006
VERSION X62006.1
KEYWORDS binding protein; polypirimidine tract binding protein; PTB gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3131)
AUTHORS Patton J.G., Mayer S.A., Nadal-Ginard B.
TITLE Characterization and molecular cloning of polypyrimidine
tract-binding protein: a component of a complex necessary for
pre-mRNA splicing
JOURNAL Genes Dev. 5(7), 1237-1251(1991).
PUBMED 1906036
REFERENCE 2 (bases 1 to 3131)
AUTHORS Patton J.G.
JOURNAL Submitted (04-MAY-1992) to the INSDC. J.G. Patton, Harvard Medical
School and, Children's Hospital/Dept of Cardiology, 300 Longwood
Ave, Boston MA 02115, USA
COMMENT See also X63571-2, X62006, X60648 & X52101.
FEATURES Location/Qualifiers
source 1..3131
/db_xref="H-InvDB:HIT000322500"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="gt-10"
/cell_line="HeLa cells"
/db_xref="taxon:9606"
CDS 46..1641
/gene="PTB-1"
/product="polypirimidine tract binding protein"
/db_xref="GOA:P26599"
/db_xref="H-InvDB:HIT000322500.13"
/db_xref="HGNC:HGNC:9583"
/db_xref="InterPro:IPR000504"
/db_xref="InterPro:IPR006536"
/db_xref="InterPro:IPR012677"
/db_xref="InterPro:IPR021790"
/db_xref="InterPro:IPR034798"
/db_xref="InterPro:IPR035000"
/db_xref="InterPro:IPR035001"
/db_xref="InterPro:IPR035979"
/db_xref="PDB:1QM9"
/db_xref="PDB:1SJQ"
/db_xref="PDB:1SJR"
/db_xref="PDB:2AD9"
/db_xref="PDB:2ADB"
/db_xref="PDB:2ADC"
/db_xref="PDB:2EVZ"
/db_xref="PDB:2N3O"
/db_xref="PDB:3ZZY"
/db_xref="PDB:3ZZZ"
/db_xref="UniProtKB/Swiss-Prot:P26599"
/protein_id="CAA43973.1"
/translation="MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDS
KKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMN
TEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSG
NLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTK
NNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT
RPDLPSGDSQPSLDQTMAAAFGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGA
GNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMS
HLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIF
PPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQAL
IDLHNHDLGENHHLRVSFSKSTI"
BASE COUNT 672 a 966 c 827 g 666 t
ORIGIN
1 attccggcgg ctccactccg tcccccgcgg tctgctctgt gtgccatgga cggcatcgtc
61 ccagatatag ccgttggtac aaagcgggga tctgacgagc ttttctctac ttgtgtcact
121 aacggaccgt ttatcatgag cagcaactcg gcttctgcag caaacggaaa tgacagcaag
181 aagttcaaag gtgacagccg aagtgcaggc gtcccctcta gagtgatcca catccggaag
241 ctccccatcg acgtcacgga gggggaagtc atctccctgg ggctgccctt tgggaaggtc
301 accaacctcc tgatgctgaa ggggaaaaac caggccttca tcgagatgaa cacggaggag
361 gctgccaaca ccatggtgaa ctactacacc tcggtgaccc ctgtgctgcg cggccagccc
421 atctacatcc agttctctaa ccacaaggag ctgaagaccg acagctctcc caaccaggcg
481 cgggcccagg cggccctgca ggcggtgaac tcggtccagt cggggaacct ggccttggct
541 gcctcggcgg cggccgtgga cgcagggatg gcgatggccg ggcagagccc tgtgctcagg
601 atcatcgtgg agaacctctt ctaccctgtg accctggatg tgctgcacca gattttctcc
661 aagttcggca cagtgttgaa gatcatcacc ttcaccaaga acaaccagtt ccaggccctg
721 ctgcagtatg cggaccccgt gagcgcccag cacgccaagc tgtcgctgga cgggcagaac
781 atctacaacg cctgctgcac gctgcgcatc gacttttcca agctcaccag cctcaacgtc
841 aagtacaaca atgacaagag ccgtgactac acacgcccag acctgccttc cggggacagc
901 cagccctcgc tggaccagac catggccgcg gccttcggcc tttccgttcc gaacgtccac
961 ggcgccctgg cccccctggc catcccctcg gcggcggcgg cagctgcggc ggcaggtcgg
1021 atcgccatcc cgggcctggc gggggcagga aattctgtat tgctggtcag caacctcaac
1081 ccagagagag tcacacccca aagcctcttt attcttttcg gcgtctacgg tgacgtgcag
1141 cgcgtgaaga tcctgttcaa taagaaggag aacgccctag tgcagatggc ggacggcaac
1201 caggcccagc tggccatgag ccacctgaac gggcacaagc tgcacgggaa gccgatccgc
1261 atcacgctct cgaagcacca gaacgtgcag ctgccccgcg agggccagga ggaccagggc
1321 ctgaccaagg actacggcaa ctcacccctg caccgcttca agaagccggg ctccaagaac
1381 ttccagaaca tattcccgcc ctcggccact ctgcacctct ccaacatccc gccctcagtc
1441 tccgaggagg atctcaaggt cctgttttcc agcaatgggg gcgtcgtcaa aggattcaag
1501 ttcttccaga aggaccgcaa gatggcactg atccagatgg gctccgtgga ggaggcggtc
1561 caggccctca ttgacctgca caaccacgac ctcggggaga accaccacct gcgggtctcc
1621 ttctccaagt ccaccatcta ggggcacagg cccccacggc cgggccccct ggcgacaact
1681 tccatcattc cagagaaaag ccactttaaa aacagctgaa gtgaccttag cagaccagag
1741 attttatttt tttaaagaga aatcagttta cctgttttta aaaaaattaa atctagttca
1801 ccttgctcac cctgcggtga cagggacagc tcaggctctt ggtgactgtg gcagcgggag
1861 ttcccggccc tccacacccg gggccagacc ctcggggcca tgccttggtg gggcctgtgt
1921 cgggcgtggg gcctgcaggt gggcgccccg accacgactt ggcttccttg tgccttaaaa
1981 aacctgcctt tcctgcagcc acacacccac ccggggtgtc ctggggaccc aaggggtggg
2041 ggggtcacac cagagagagg cagggggcct ggccggctcc tgcaggatca tgcagctggg
2101 gcgcggcggc cgcgctgcga gcaccccaac cccagccctc taatcaagtc acgtgattct
2161 cccttcaccc cgcccccagg gccttccctt ccttgccccc aggcgggctc cccgctgctc
2221 cagctgcgga ctggtcgaca taatctctgt attatatact ttgcagttgc agacgtctgt
2281 gcctagcaat atttccagtt gaccaaatat tctaatcttt tttcatttat atgcaaaaga
2341 aatagtttta agtaactttt tatagcaaga tgatacaatg gtatgagtgt aatctaaact
2401 tccttgtggt attaccttgt atgctgttac ttttatttta ttccttgtaa ttaagtcaca
2461 ggcaggaccc agtttccaga gagcaggcgg ggccgcccag tgggtcaggc acagggagcc
2521 ccggtcctat cttagagccc ctgagcttca gggaagggcg gcgtgtcgcg cctctggcat
2581 cgctccggtt gccttacacc acgccttcac ctgcagtcgc ctagaaaact tgctctcaaa
2641 cttcagggtt ttttcttctt caaatttgga ccaaagtctc atttctgtgt tttgcctgcc
2701 tctgatgctg ggacccggaa agcgggcgct cctgtctttg tgctctttct accgcccccg
2761 cgtcctgtcc cgggggctct cctaggatcc cctttccgta aaagcgtgta acaagggtgt
2821 aaatatttat aattttttat acctgttgtg agacccgagg ggcggcggcg cggtttttta
2881 tggtgacaca aatgtatatt ttgctaacag caattccagg ctcagtattg tgaccgcgga
2941 gccacagggg accccacgca cattccgtgc cttacccgat ggcttgtgac gcggagagaa
3001 ccgattaaaa ccgtttgaga aactcctccc ttgtctagcc ctgtgttcgc tgtggacgct
3061 gtagacacag gttggccagt ctgtacctgg acttcgaata aatcttctgt atcctcaaaa
3121 aaaaaaaaaa a
//