LOCUS X61615 3591 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for leukemia inhibitory factor (LIF) receptor.
ACCESSION X61615
VERSION X61615.1
KEYWORDS leukemia-inhibitory factor receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3591)
AUTHORS Gearing D.P., Thut C.J., VandenBos T., Gimpel S.D., Delaney P.B.,
King J., Price V., Cosman D., Beckmann P.M.
TITLE Leukemia inhibitory factor receptor is structurally related to the
IL-6 signal transducer, gp130
JOURNAL EMBO J. 10(10), 2839-2848(1991).
PUBMED 1915266
FEATURES Location/Qualifiers
source 1..3591
/db_xref="H-InvDB:HIT000322465"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
sig_peptide 179..310
/note="leukemia inhibitory factor receptor"
CDS 179..3472
/product="leukemia inhibitory factor receptor"
/db_xref="GOA:P42702"
/db_xref="H-InvDB:HIT000322465.14"
/db_xref="HGNC:HGNC:6597"
/db_xref="InterPro:IPR003529"
/db_xref="InterPro:IPR003961"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036116"
/db_xref="InterPro:IPR040817"
/db_xref="InterPro:IPR040901"
/db_xref="PDB:3E0G"
/db_xref="UniProtKB/Swiss-Prot:P42702"
/protein_id="CAA43805.1"
/translation="MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNS
QKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPA
LSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDR
GSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFV
EIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEK
VLSALIGHTNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPD
TPQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTLVESFSGKYVRLKRAEAPTNES
YQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVK
LSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFR
IRCSTETFWKWSKWSNKKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANG
KILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIASM
EIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNST
ETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSI
LVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGRSDIKVKNITDISQKTLRI
ADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAILIPVAVAVIVGVVTSI
LCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEMNPCTPNNVEVLETR
SAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPNPAADEAGGTAQV
IYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEEDLDKTAGYRP
QANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSNGGGWSFT
NFFQNKPND"
mat_peptide 311..3469
/product="leukemia inhibitory factor receptor"
BASE COUNT 1145 a 696 c 736 g 1014 t
ORIGIN
1 agatcttgga acgagacgac ctgctctctc tcccagaacg tgtctctgct gcaaggcacc
61 gggccctttc gctctgcaga actgcacttg caagaccatt atcaactcct aatcccagct
121 cagaaaggga gcctctgcga ctcattcatc gccctccagg actgactgca ttgcacagat
181 gatggatatt tacgtatgtt tgaaacgacc atcctggatg gtggacaata aaagaatgag
241 gactgcttca aatttccagt ggctgttatc aacatttatt cttctatatc taatgaatca
301 agtaaatagc cagaaaaagg gggctcctca tgatttgaag tgtgtaacta acaatttgca
361 agtgtggaac tgttcttgga aagcaccctc tggaacaggc cgtggtactg attatgaagt
421 ttgcattgaa aacaggtccc gttcttgtta tcagttggag aaaaccagta ttaaaattcc
481 agctctttca catggtgatt atgaaataac aataaattct ctacatgatt ttggaagttc
541 tacaagtaaa ttcacactaa atgaacaaaa cgtttcctta attccagata ctccagagat
601 cttgaatttg tctgctgatt tctcaacctc tacattatac ctaaagtgga acgacagggg
661 ttcagttttt ccacaccgct caaatgttat ctgggaaatt aaagttctac gtaaagagag
721 tatggagctc gtaaaattag tgacccacaa cacaactctg aatggcaaag atacacttca
781 tcactggagt tgggcctcag atatgccctt ggaatgtgcc attcattttg tggaaattag
841 atgctacatt gacaatcttc atttttctgg tctcgaagag tggagtgact ggagccctgt
901 gaagaacatt tcttggatac ctgattctca gactaaggtt tttcctcaag ataaagtgat
961 acttgtaggc tcagacataa cattttgttg tgtgagtcaa gaaaaagtgt tatcagcact
1021 gattggccat acaaactgcc ccttgatcca tcttgatggg gaaaatgttg caatcaagat
1081 tcgtaatatt tctgtttctg caagtagtgg aacaaatgta gtttttacaa ccgaagataa
1141 catatttgga accgttattt ttgctggata tccaccagat actcctcaac aactgaattg
1201 tgagacacat gatttaaaag aaattatatg tagttggaat ccaggaaggg tgacagcgtt
1261 ggtgggccca cgtgctacaa gctacacttt agttgaaagt ttttcaggaa aatatgttag
1321 acttaaaaga gctgaagcac ctacaaacga aagctatcaa ttattatttc aaatgcttcc
1381 aaatcaagaa atatataatt ttactttgaa tgctcacaat ccgctgggtc gatcacaatc
1441 aacaatttta gttaatataa ctgaaaaagt ttatccccat actcctactt cattcaaagt
1501 gaaggatatt aattcaacag ctgttaaact ttcttggcat ttaccaggca actttgcaaa
1561 gattaatttt ttatgtgaaa ttgaaattaa gaaatctaat tcagtacaag agcagcggaa
1621 tgtcacaatc aaaggagtag aaaattcaag ttatcttgtt gctctggaca agttaaatcc
1681 atacactcta tatacttttc ggattcgttg ttctactgaa actttctgga aatggagcaa
1741 atggagcaat aaaaaacaac atttaacaac agaagccagt ccttcaaagg ggcctgatac
1801 ttggagagag tggagttctg atggaaaaaa tttaataatc tattggaagc ctttacccat
1861 taatgaagct aatggaaaaa tactttccta caatgtatcg tgttcatcag atgaggaaac
1921 acagtccctt tctgaaatcc ctgatcctca gcacaaagca gagatacgac ttgataagaa
1981 tgactacatc atcagcgtag tggctaaaaa ttctgtgggc tcatcaccac cttccaaaat
2041 agcgagtatg gaaattccaa atgatgatct caaaatagaa caagttgttg ggatgggaaa
2101 ggggattctc ctcacctggc attacgaccc caacatgact tgcgactacg tcattaagtg
2161 gtgtaactcg tctcggtcgg aaccatgcct tatggactgg agaaaagttc cctcaaacag
2221 cactgaaact gtaatagaat ctgatgagtt tcgaccaggt ataagatata attttttcct
2281 gtatggatgc agaaatcaag gatatcaatt attacgctcc atgattggat atatagaaga
2341 attggctccc attgttgcac caaattttac tgttgaggat acttctgcag attcgatatt
2401 agtaaaatgg gaagacattc ctgtggaaga acttagaggc tttttaagag gatatttgtt
2461 ttactttgga aaaggagaaa gagacacatc taagatgagg gttttagaat caggtcgttc
2521 tgacataaaa gttaagaata ttactgacat atcccagaag acactgagaa ttgctgatct
2581 tcaaggtaaa acaagttacc acctggtctt gcgagcctat acagatggtg gagtgggccc
2641 ggagaagagt atgtatgtgg tgacaaagga aaattctgtg ggattaatta ttgccattct
2701 catcccagtg gcagtggctg tcattgttgg agtggtgaca agtatccttt gctatcggaa
2761 acgagaatgg attaaagaaa ccttctaccc tgatattcca aatccagaaa actgtaaagc
2821 attacagttt caaaagagtg tctgtgaggg aagcagtgct cttaaaacat tggaaatgaa
2881 tccttgtacc ccaaataatg ttgaggttct ggaaactcga tcagcatttc ctaaaataga
2941 agatacagaa ataatttccc cagtagctga gcgtcctgaa gatcgctctg atgcagagcc
3001 tgaaaaccat gtggttgtgt cctattgtcc acccatcatt gaggaagaaa taccaaaccc
3061 agccgcagat gaagctggag ggactgcaca ggttatttac attgatgttc agtcgatgta
3121 tcagcctcaa gcaaaaccag aagaagaaca agaaaatgac cctgtaggag gggcaggcta
3181 taagccacag atgcacctcc ccattaattc tactgtggaa gatatagctg cagaagagga
3241 cttagataaa actgcgggtt acagacctca ggccaatgta aatacatgga atttagtgtc
3301 tccagactct cctagatcca tagacagcaa cagtgagatt gtctcatttg gaagtccatg
3361 ctccattaat tcccgacaat ttttgattcc tcctaaagat gaagactctc ctaaatctaa
3421 tggaggaggg tggtccttta caaacttttt tcagaacaaa ccaaacgatt aacagtgtca
3481 ccgtgtcact tcagtcagcc atctcaataa gctcttactg ctagtgttgc tacatcagca
3541 ctgggcattc ttggagggat cctgtgaagt attgttagga ggtgaacttc a
//