LOCUS X61157 3136 bp mRNA linear HUM 23-MAR-1993
DEFINITION H.sapiens mRNA for beta-adrenergic receptor kinase.
ACCESSION X61157
VERSION X61157.1
KEYWORDS beta-adrenergic receptor kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3136)
AUTHORS Benovic J.L., Stone W.C., Huebner K., Croce C., Caron M.G.,
Lefkowitz R.J.
TITLE cDNA cloning and chromosomal localization of the human
beta-adrenergic receptor kinase
JOURNAL FEBS Lett. 283(1), 122-126(1991).
PUBMED 2037065
FEATURES Location/Qualifiers
source 1..3136
/db_xref="H-InvDB:HIT000322454"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 108..2177
/product="beta-adrenergic receptor kinase"
/db_xref="GOA:P25098"
/db_xref="H-InvDB:HIT000322454.14"
/db_xref="HGNC:HGNC:289"
/db_xref="InterPro:IPR000239"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR000961"
/db_xref="InterPro:IPR001849"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR011993"
/db_xref="InterPro:IPR016137"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR036305"
/db_xref="PDB:1BAK"
/db_xref="PDB:3CIK"
/db_xref="PDB:3KRW"
/db_xref="PDB:3KRX"
/db_xref="PDB:3V5W"
/db_xref="PDB:4MK0"
/db_xref="PDB:4PNK"
/db_xref="PDB:5HE1"
/db_xref="PDB:5UKK"
/db_xref="PDB:5UKL"
/db_xref="PDB:5UUU"
/db_xref="PDB:5UVC"
/db_xref="PDB:5WG3"
/db_xref="PDB:5WG4"
/db_xref="PDB:5WG5"
/db_xref="PDB:6C2Y"
/db_xref="UniProtKB/Swiss-Prot:P25098"
/protein_id="CAA43470.1"
/translation="MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQ
KYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERV
ARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGD
VFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKRDTGKMYA
MKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNG
GDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRIS
DLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFR
QHKTKDKHEIDRMTLTMAVELPDSFSPELHSLLEGLLQRDVNRRLGCLGRGAQEVKES
PFFRSLDWQMVFLQRYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRN
FPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMS
KMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKI
RGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLVQ
RGSANGL"
BASE COUNT 608 a 989 c 964 g 575 t
ORIGIN
1 gggtaccgag ctcgaattcc ggctcggcct cgggcgcggc cgagcgccgc gcgagcagga
61 gcggcggcgg cggcggcggc ggcgggagga ggcagcgccg gcccaagatg gcggacctgg
121 aggcggtgct ggccgacgtg agctacctga tggccatgga gaagagcaag gccacgccgg
181 ccgcgcgcgc cagcaagaag atactgctgc ccgagcccag catccgcagt gtcatgcaga
241 agtacctgga ggaccggggc gaggtgacct ttgagaagat cttttcccag aagctggggt
301 acctgctctt ccgagacttc tgcctgaacc acctggagga ggccaggccc ttggtggaat
361 tctatgagga gatcaagaag tacgagaagc tggagacgga ggaggagcgt gtggcccgca
421 gccgggagat cttcgactca tacatcatga aggagctgct ggcctgctcg catcccttct
481 cgaagagtgc cactgagcat gtccaaggcc acctggggaa gaagcaggtg cctccggatc
541 tcttccagcc atacatcgaa gagatttgtc aaaacctccg aggggacgtg ttccagaaat
601 tcattgagag cgataagttc acacggtttt gccagtggaa gaatgtggag ctcaacatcc
661 acctgaccat gaatgacttc agcgtgcatc gcatcattgg gcgcgggggc tttggcgagg
721 tctatgggtg ccggaagcgt gacacaggca agatgtacgc catgaagtgc ctggacaaaa
781 agcgcatcaa gatgaagcag ggggagaccc tggccctgaa cgagcgcatc atgctctcgc
841 tcgtcagcac tggggactgc ccattcattg tctgcatgtc atacgcgttc cacacgccag
901 acaagctcag cttcatcctg gacctcatga acggtgggga cctgcactac cacctctccc
961 agcacggggt cttctcagag gctgacatgc gcttctatgc ggccgagatc atcctgggcc
1021 tggagcacat gcacaaccgc ttcgtggtct accgggacct gaagccagcc aacatccttc
1081 tggacgagca tggccacgtg cggatctcgg acctgggcct ggcctgtgac ttctccaaga
1141 agaagcccca tgccagcgtg ggcacccacg ggtacatggc tccggaggtc ctgcagaagg
1201 gcgtggccta cgacagcagt gccgactggt tctctctggg gtgcatgctc ttcaagttgc
1261 tgcgggggca cagccccttc cggcagcaca agaccaaaga caagcatgag atcgaccgca
1321 tgacgctgac gatggccgtg gagctgcccg actccttctc ccctgaacta cactccctgc
1381 tggaggggtt gctgcagagg gatgtcaacc ggagattggg ctgcctgggc cgaggggctc
1441 aggaggtgaa agagagcccc tttttccgct ccctggactg gcagatggtc ttcttgcaga
1501 ggtaccctcc cccgctgatc cccccacgag gggaggtgaa cgcggccgac gccttcgaca
1561 ttggctcctt cgatgaggag gacacaaaag gaatcaagtt actggacagt gatcaggagc
1621 tctaccgcaa cttccccctc accatctcgg agcggtggca gcaggaggtg gcagagactg
1681 tcttcgacac catcaacgct gagacagacc ggctggaggc tcgcaagaaa gccaagaaca
1741 agcagctggg ccatgaggaa gactacgccc tgggcaagga ctgcatcatg catggctaca
1801 tgtccaagat gggcaacccc tttctgaccc agtggcagcg gcggtacttc tacctgttcc
1861 ccaaccgcct cgagtggcgg ggcgagggcg aggccccgca gagcctgctg accatggagg
1921 agatccagtc ggtggaggag acgcagatca aggagcgcaa gtgcctgctc ctcaagatcc
1981 gcggtgggaa acagttcatt ttgcagtgcg atagcgaccc tgagctggtg cagtggaaga
2041 aggagctgcg cgacgcctac cgcgaggccc agcagctggt gcagcgggtg cccaagatga
2101 agaacaagcc gcgctcgccc gtggtggagc tgagcaaggt gccgctggtc cagcgcggca
2161 gtgccaacgg cctctgaccc gcccacccgc cttttataaa cctctaattt attttgtcga
2221 atttttatta tttgttttcc cgccaagcga aaaggtttta ttttgtaatt attgtgattt
2281 cccgtggccc cagcctggcc cagctccccc gggaggcccc gcttgcctcg gctcctgctg
2341 caccaaccca gccgctgccc ggcgccctct gtcctgactt caggggctgc ccgctcccag
2401 tgtcttcctg tgggggaaga gcacagccct cccgcccctt ccccgaggga tgatgccaca
2461 ccaagctgtg ccaccctggg ctctgtgggc tgcacttgtg ccatgggact gtgggtggcc
2521 catcccccct caccaggggc aggcacagca cagggatccg acttgaattt tcccactgca
2581 ccccctcctg ctgcagaggg gcaggccctg cactgtcctg ctccacagtg ttggcgagag
2641 gaggggcccg ttgtctccct ggccctcaag gctcccacag tgactcgggc tcctgtgccc
2701 ttattcagga aaagcctctg tgtcactggc tgcctccact cccacttccc tgacactgcg
2761 gggcttggct gagagagtgg cattggcagc aggtgctgct accctccctg ctgtcccctc
2821 ttgccccaac ccccagcacc cgggctcagg gaccacagca aggcacctgc aggttgggcc
2881 atactggcct cgcctggcct gaggtctcgc tgatgctggg ctgggtgcga ccccatctgc
2941 ccaggacggg gccggccagg tgggcgggca gcacagcaag gaggctggct ggggcctatc
3001 agtgtgcccc ccatcctggc ccatcagtgt acccccgccc agactggcca gccccacagc
3061 ccacgtcctg tcagtgccgc cgcctcgccc accgcatgcc ccctgtgcca gtgctctgcc
3121 tgtgtgtgtg cactct
//