LOCUS X59871 2910 bp mRNA linear HUM 18-APR-2005
DEFINITION Human TCF-1 mRNA for T cell factor 1 (splice form C).
ACCESSION X59871 X55328
VERSION X59871.1
KEYWORDS DNA-binding protein; HMG box; T cell factor 1; TCF-1 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2910)
AUTHORS van de Wetering M.
JOURNAL Submitted (28-MAY-1991) to the INSDC. M. Van De Wetering, Dept of
Clinical Immunology, University Hospital, P.O. Box 85500, 3508 GA
Utrecht, The Netherlands
REFERENCE 3 (bases 1 to 2910)
AUTHORS van de Wetering M., Oosterwegel M., Dooijes D., Clevers H.
TITLE Identification and cloning of TCF-1, a T lymphocyte-specific
transcription factor containing a sequence-specific HMG box
JOURNAL EMBO J. 10(1), 123-132(1991).
PUBMED 1989880
COMMENT See also X59869-X59871.
FEATURES Location/Qualifiers
source 1..2910
/db_xref="H-InvDB:HIT000322356"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="cDNA"
/cell_line="Jurkat and HPB-ALL"
/cell_type="T lymphocyte"
/db_xref="taxon:9606"
mRNA 1..2910
/gene="TCF-1"
/experiment="experimental evidence, no additional details
recorded"
CDS 80..886
/gene="TCF-1"
/product="T cell factor 1, splice form C"
/db_xref="GOA:P36402"
/db_xref="H-InvDB:HIT000322356.13"
/db_xref="HGNC:HGNC:11639"
/db_xref="InterPro:IPR009071"
/db_xref="InterPro:IPR013558"
/db_xref="InterPro:IPR024940"
/db_xref="InterPro:IPR027397"
/db_xref="InterPro:IPR028785"
/db_xref="InterPro:IPR036910"
/db_xref="UniProtKB/Swiss-Prot:P36402"
/protein_id="CAA42528.1"
/translation="MYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQ
LSLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPS
LMLGSGVPGHPAAIPHPAIVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNA
FMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLY
PGWSARDNYGKKKRRSREKHQESTTDPGSPKKCRARFGLNQQTDWCGPCR"
misc_feature 539..769
/note="HMG box"
misc_feature 810
/note="alternative splice site"
BASE COUNT 782 a 860 c 671 g 597 t
ORIGIN
1 gcccaggtga ctgactaatc cgccgccttc aggagacaga attggccaag gcctgaaggc
61 cccggagtgc accagcggca tgtacaaaga gaccgtctac tccgccttca atctgctcat
121 gcattaccca cccccctcgg gagcagggca gcacccccag ccgcagcccc cgctgcacaa
181 ggccaatcag cccccccacg gtgtccccca actctctctc tacgaacatt tcaacagccc
241 acatcccacc cctgcacctg cggacatcag ccagaagcaa gttcacaggc ctctgcagac
301 ccctgacctc tctggcttct actccctgac ctcaggcagc atggggcagc tcccccacac
361 tgtgagctgg ttcacccacc catccttgat gctaggttct ggtgtacctg gtcacccagc
421 agccatcccc cacccggcca ttgtgccccc ctcagggaag caggagctgc agcccttcga
481 ccgcaacctg aagacacaag cagagtccaa ggcagagaag gaggccaaga agccaaccat
541 caagaagccc ctcaatgcct tcatgctgta catgaaggag atgagagcca aggtcattgc
601 agagtgcaca cttaaggaga gcgctgccat caaccagatc ctgggccgca ggtggcacgc
661 gctgtcgcga gaagagcagg ccaagtacta tgagctggcc cgcaaggaga ggcagctgca
721 catgcagcta tacccaggct ggtcagcgcg ggacaactac gggaagaaga agaggcggtc
781 gagggaaaag caccaagaat ccaccacaga ccctggctcg cctaagaaat gccgtgctcg
841 ctttggcctc aaccagcaga cggattggtg tggtccgtgc agataactct cttcactatt
901 cctaggagga aaaagaaatg cattcggtac ttacccggag aaggccgctg ccccagcccc
961 gttccttccg atgacagtgc tctaggctgc cccgggtccc cagctcccca ggactcaccc
1021 tcataccatc tgctgccccg cttccccaca gaactgctta ctagccctgc ggagcggcac
1081 ctacatcccc aggtctctcc actgctctca gcctcccaac cccagggccc ccacaggccc
1141 cccgcagcac cctgcagagc acacaggtac agcaacagga atctcagaga caggtggcct
1201 agcaggcaca ggacacctgg ccgcctccag gagcctaccc cctgaaaatg acagagaccc
1261 agatctcatg gaaactggca ggggtcctgt taacgtcatc tcagggtcca gaccctgaag
1321 atttcagagg ctgcagaact tctgcctgaa cctggggtca tcgattcaaa ctgctccaag
1381 tggtgggaat cagatctgtc ttgatgtgtc atctaattaa gggaatccct tgtacctatg
1441 actccgtcga tctattcttt gtaccatctg tcttgccagc cagaagcctc tgcctcccta
1501 gcttttctgc tataggtcag agatgggctg aactgagcct agctaccttc tctacccatc
1561 tcccccatcc cccactgcca caccctcccc attcagacac ttcatggacc aagaatgagc
1621 tggtttgtca aacaacatgt gagcatggtc acaagcacaa agctcaagat gacagctctt
1681 ctaaggaaat ggagaagctc tgtttataaa aacaaaaaca aaaccagctg ctactcataa
1741 gttggaccag aggaagcccc ttactatgat ctcaggagct tgcaagaagc aggaagggga
1801 atggaatagg ttaagtttag gcctatcaac ctaagcaaca gaaataatct gacactacct
1861 tatcaggcaa attggggagg ggagggtgta tctagctcta gttcaaatta tttggaagtg
1921 ttccctgaga aacccaccag cctaagaagc tctggcccca ggcttgtcac tagcagctgc
1981 agtcaacagt tcaaagaagt catggcccaa atccagtgtg cacccctccc cattcacaga
2041 gcctttttca caattccatt tccagttcat ctatggcagt ccagccagct tctgggcagc
2101 ttgagagggc aaacccaaaa cctcatgaca gccagagcct gtctttcagc attcagtcgc
2161 ctgggaagct ccagtttccc catggggctg cgggacagag gaccattaca actagatcaa
2221 ggagcccaga aaacctccag tagtggacaa caggttttca ccatagccta cgttaaccca
2281 tttttgagcc aagcttcaac cctcagcctt gaaaaacaag tctttaattt aatttttgtt
2341 ttttgcctaa atccaaagaa aaagggctgc cgggccaggc gcggtcgtca cgcctgtaat
2401 cccagcactt tggcaggccg aggcaggtgg atcacctgac gtcagtagtt tgagaccagc
2461 ctggccaaca tggtgaaacc ctgtatctac taaaaataca aaaattagcc ggacgtggtg
2521 gtgcgcgcat gtaatcccag ctactcggga ggctgaggcg gaagaatcac ttgaacccgg
2581 gaggcggagg ttccagtgag ccgagatggc gctattgcac tccagtctgg gtaacaggga
2641 gactgcatct caaaaaaaaa aaaaaaaaaa aagggctgtc catgtattca cacacccctc
2701 aaaaaaagcc tttagttcct actttagcca ctggtttctc agaatccaaa gatcacatat
2761 tctagtgtaa cactgcaaga agtcttgaga aaaagattat tgtagtgttc aaaatatttt
2821 tgtattgtta atgcatcatc atagaaaaac ttttaaacat gagaataaag atacttttta
2881 ctgggtttgt ttttcaaagc ctgaaaaaaa
//