LOCUS X59740 3719 bp mRNA linear HUM 21-OCT-2008
DEFINITION Human ZFX mRNA for put. transcription activator, isoform 3.
ACCESSION X59740 X17312
VERSION X59740.1
KEYWORDS sex determination; transcription activator; ZFX gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3719)
AUTHORS Schneider-Gadicke A., Beer-Romero P., Brown L., Mardon G., Luoh S.,
Page D.C.
TITLE Putative transcription activator with alternative isoforms encoded
by human ZFX gene
JOURNAL Nature 342(6250), 708-711(1989).
PUBMED 2512506
FEATURES Location/Qualifiers
source 1..3719
/db_xref="H-InvDB:HIT000322341"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..3719
/gene="ZFX"
/note="alternatively spliced isoform 3"
/experiment="experimental evidence, no additional details
recorded"
CDS 428..2842
/gene="ZFX"
/product="ZFX product, isoform 3"
/note="alternatively spliced isoform 3"
/db_xref="GOA:P17010"
/db_xref="H-InvDB:HIT000322341.15"
/db_xref="HGNC:HGNC:12869"
/db_xref="InterPro:IPR006794"
/db_xref="InterPro:IPR013087"
/db_xref="InterPro:IPR036236"
/db_xref="UniProtKB/Swiss-Prot:P17010"
/protein_id="CAA42418.1"
/translation="MDEDGLELQQEPNSFFDATGADGTHMDGDQIVVEVQETVFVSDV
VDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEADVSETVIIPEQVLDSDV
TEEVSLAHCTVPDDVLASDITSASMSMPEHVLTGDSIHVSDVGHVGHVGHVEHVVHDS
VVEAEIVTDPLTTDVVSEEVLVADCASEAVIDANGIPVDQQDDDKGNCEDYLMISLDD
AGKIEHDGSSGMTMDTESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEP
ENDHGVELLDQNSSIRVPREKMVYMTVNDSQPEDEDLNVAEIADEVYMEVIVGEEDAA
AAGHAPVHEQQMDDNEIKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRL
AKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHL
AKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMV
HKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHM
RIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHAL
IHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAA
HKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKTH
SGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHH
KEVGLP"
BASE COUNT 1095 a 738 c 831 g 1055 t
ORIGIN
1 gccggcctgc agcacccgcc accgtcgcgg ccgcccgcaa cgtccgtccg gttcttgcta
61 tattgcccca ggctggtctc gaactcctgg gctcaagccg ttctcccgcc tcccactgcc
121 cgcctgtcac tgccgtctgt tccctgagct gtcgtttacg ctgggaaaga catagaagaa
181 ctattaagaa gatagaattg ttttgctgcg cagtacagca acagtggatg ttcaagatta
241 agattagagt caagttgtgt gattaagaca gacagtcttc ctctgtcatc caggctggaa
301 tgcagtgcag tggtgcaaat ttggctcact gcagcctctg ccttctgtgt tcaagtgatt
361 cttcttctgc ctcagcctct cgagtagctg ggattacagg agctgtgact gatgagaatt
421 aaaggccatg gatgaagatg ggcttgaatt acaacaagag ccaaactcat tttttgatgc
481 aacaggagct gatggtacac acatggatgg tgatcaaatt gttgtggaag tacaagaaac
541 tgtttttgtt tcagatgttg tggattcaga cataactgtg cataactttg ttcctgatga
601 cccagattca gttgtaatcc aagatgttat tgaggacgtt gttatagaag atgttcagtg
661 cccagatatc atggaagaag cagatgtgtc tgaaacggtc atcattcctg agcaagtgct
721 ggactcagat gtaactgaag aagtttcttt agcacattgc acagtcccag atgatgtttt
781 agcttctgac attacttcag cctcaatgtc tatgccagaa cacgtcttga cgggtgattc
841 tatacatgtg tctgacgttg gacatgttgg acatgttgga catgttgaac atgtggttca
901 tgatagtgta gtggaagcag aaattgtcac tgatcctctg actaccgacg tagtttcaga
961 agaagtattg gtagcagact gtgcctctga agcagtcata gatgccaatg ggatccctgt
1021 ggaccagcag gatgatgaca aaggcaactg tgaggactac cttatgattt ccttggatga
1081 tgctggaaaa atagaacacg atggttcttc tggaatgacc atggacacag agtcggaaat
1141 tgatccttgt aaagtggatg gcacttgccc tgaggtcatc aaggtgtaca tttttaaagc
1201 tgaccctgga gaagatgact taggtggaac tgtagacatt gtggagagtg agcctgagaa
1261 tgatcatgga gttgaactgc ttgatcagaa cagcagtatt cgtgttccca gggaaaagat
1321 ggtttatatg actgtcaatg actctcagcc agaagatgaa gatttaaatg ttgctgaaat
1381 cgctgacgaa gtttatatgg aagtgatcgt aggagaggag gatgctgcag cagcaggaca
1441 cgcgccggtg cacgagcagc aaatggatga caatgaaatc aaaaccttca tgccgattgc
1501 atgggcagca gcttatggta ataattctga tggaattgaa aaccggaatg gcactgcaag
1561 tgccctcttg cacatagatg agtctgctgg cctcggcaga ctggctaaac aaaaaccaaa
1621 gaaaaggaga agacctgatt ccaggcagta ccaaacagca ataattattg gccctgatgg
1681 acatcctttg actgtctatc cttgcatgat ttgtgggaag aagtttaagt cgagaggttt
1741 tttgaaaagg cacatgaaaa accatcccga acaccttgcc aagaagaaat accgctgtac
1801 tgactgtgat tacactacca acaagaagat aagtttacac aaccacctgg agagccacaa
1861 gctgaccagc aaggcagaga aggccattga atgcgatgag tgtgggaagc atttctctca
1921 tgcaggggct ttgtttactc acaaaatggt gcataaggaa aaaggagcca acaaaatgca
1981 caagtgtaaa ttctgtgaat acgagacagc tgaacaaggg ttattgaatc gccacctctt
2041 ggcagtccac agcaagaact ttcctcatat ttgtgtggag tgtggtaagg gttttcgtca
2101 cccgtcagag ctcaaaaagc acatgagaat ccatactggg gagaagccgt accaatgcca
2161 gtactgcgaa tataggtctg cagactcttc taacttgaaa acgcatgtca aaactaagca
2221 tagtaaagag atgccattca agtgtgacat ttgtcttctg actttctcgg ataccaaaga
2281 ggtgcagcaa catgctctta tccaccaaga aagcaaaaca caccagtgtt tgcattgcga
2341 ccacaagagt tcgaactcaa gtgatttgaa acgacacata atttcagttc acacgaaaga
2401 ctacccccat aagtgtgaca tgtgtgataa aggctttcac aggccttcag aactcaagaa
2461 acacgtggct gcccacaagg gcaaaaaaat gcaccagtgt agacattgtg actttaagat
2521 tgcagatcca tttgttctaa gtcgccatat tctctcagtt cacacaaagg atcttccatt
2581 taggtgcaag agatgtagaa agggatttag gcaacagagt gagcttaaaa agcatatgaa
2641 gacacacagt ggcaggaaag tgtatcagtg tgagtactgt gagtatagca ctacagatgc
2701 ctcaggcttt aaacggcacg ttatttccat tcacacgaaa gactatcctc accggtgtga
2761 gtactgcaag aaaggcttcc gaagaccttc agaaaagaac cagcacataa tgcgacatca
2821 taaagaagtt ggcctgccct aacaatactt ctacagaacg tttgtagaga tattggcctt
2881 gaagcagaaa attcatttta aagccaatca gtctcattca catacaatac tgtatattga
2941 tttatgctgt gtacaaatag aattattact tctagttgac ttttttttaa atatacattt
3001 tgctcagtag tgtgttctga attctattca gtttgtttaa taaataggga aaactggcaa
3061 catgctagtt acttttaata aagtaatccc tgattctata ccgaagtttt atatcttaga
3121 attttatatt tatttaaata tttaccttgc ttaccttgat ggtactcttc taagaccatt
3181 aacttaaggt aactttatat tggtaactct gaaagtattc atgttgactc atttttttcc
3241 ccatacattt ctcacaataa aattgtcaga gacatctact aatataaatg ggagatttta
3301 cagtcaggtc taattatcat aacatggaag tcatttactt gtcttgctta atattttcag
3361 accacttgac agtgaaagtt tccatttgag ctgttgcgtc cctggctttg ctgagtaaag
3421 agcagtggct gggttcgtgt ttacttttca aatatacttc cttttcggct ttctttggat
3481 tatttacatc ttttgtccag cgtagcaaac ttttagaaaa ccttattgaa aaactgtgct
3541 tgctcatgtt gtattttgat tattctgtct gtgcggcttc atcttggaat ggttgtgtgc
3601 tacaaatgac acttactgag gactgcattt tggaatctcc tagaggtaac tcatggctta
3661 taggatcttt tgcaacttta tgtatgtaaa tgtaccctga attatatata tacacatat
//