LOCUS X59739 5527 bp mRNA linear HUM 21-OCT-2008
DEFINITION Human ZFX mRNA for put. transcription activator, isoform 2.
ACCESSION X59739 X17312
VERSION X59739.1
KEYWORDS sex determination; transcription activator; ZFX gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5527)
AUTHORS Schneider-Gadicke A., Beer-Romero P., Brown L., Mardon G., Luoh S.,
Page D.C.
TITLE Putative transcription activator with alternative isoforms encoded
by human ZFX gene
JOURNAL Nature 342(6250), 708-711(1989).
PUBMED 2512506
FEATURES Location/Qualifiers
source 1..5527
/db_xref="H-InvDB:HIT000322340"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..5527
/gene="ZFX"
/note="alternatively spliced isoform 2"
/experiment="experimental evidence, no additional details
recorded"
CDS 79..2493
/gene="ZFX"
/product="ZFX product, isoform 2"
/note="alternatively spliced isoform 2"
/db_xref="GOA:P17010"
/db_xref="H-InvDB:HIT000322340.14"
/db_xref="HGNC:HGNC:12869"
/db_xref="InterPro:IPR006794"
/db_xref="InterPro:IPR013087"
/db_xref="InterPro:IPR036236"
/db_xref="UniProtKB/Swiss-Prot:P17010"
/protein_id="CAA42417.1"
/translation="MDEDGLELQQEPNSFFDATGADGTHMDGDQIVVEVQETVFVSDV
VDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEADVSETVIIPEQVLDSDV
TEEVSLAHCTVPDDVLASDITSASMSMPEHVLTGDSIHVSDVGHVGHVGHVEHVVHDS
VVEAEIVTDPLTTDVVSEEVLVADCASEAVIDANGIPVDQQDDDKGNCEDYLMISLDD
AGKIEHDGSSGMTMDTESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEP
ENDHGVELLDQNSSIRVPREKMVYMTVNDSQPEDEDLNVAEIADEVYMEVIVGEEDAA
AAGHAPVHEQQMDDNEIKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRL
AKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHL
AKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMV
HKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHM
RIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHAL
IHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAA
HKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKTH
SGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHH
KEVGLP"
BASE COUNT 1671 a 1022 c 1141 g 1693 t
ORIGIN
1 gccggcctgc agcacccgcc accgtcgcgg ccgcccgcaa cgtccgtccg gagctgtgac
61 tgatgagaat taaaggccat ggatgaagat gggcttgaat tacaacaaga gccaaactca
121 ttttttgatg caacaggagc tgatggtaca cacatggatg gtgatcaaat tgttgtggaa
181 gtacaagaaa ctgtttttgt ttcagatgtt gtggattcag acataactgt gcataacttt
241 gttcctgatg acccagattc agttgtaatc caagatgtta ttgaggacgt tgttatagaa
301 gatgttcagt gcccagatat catggaagaa gcagatgtgt ctgaaacggt catcattcct
361 gagcaagtgc tggactcaga tgtaactgaa gaagtttctt tagcacattg cacagtccca
421 gatgatgttt tagcttctga cattacttca gcctcaatgt ctatgccaga acacgtcttg
481 acgggtgatt ctatacatgt gtctgacgtt ggacatgttg gacatgttgg acatgttgaa
541 catgtggttc atgatagtgt agtggaagca gaaattgtca ctgatcctct gactaccgac
601 gtagtttcag aagaagtatt ggtagcagac tgtgcctctg aagcagtcat agatgccaat
661 gggatccctg tggaccagca ggatgatgac aaaggcaact gtgaggacta ccttatgatt
721 tccttggatg atgctggaaa aatagaacac gatggttctt ctggaatgac catggacaca
781 gagtcggaaa ttgatccttg taaagtggat ggcacttgcc ctgaggtcat caaggtgtac
841 atttttaaag ctgaccctgg agaagatgac ttaggtggaa ctgtagacat tgtggagagt
901 gagcctgaga atgatcatgg agttgaactg cttgatcaga acagcagtat tcgtgttccc
961 agggaaaaga tggtttatat gactgtcaat gactctcagc cagaagatga agatttaaat
1021 gttgctgaaa tcgctgacga agtttatatg gaagtgatcg taggagagga ggatgctgca
1081 gcagcaggac acgcgccggt gcacgagcag caaatggatg acaatgaaat caaaaccttc
1141 atgccgattg catgggcagc agcttatggt aataattctg atggaattga aaaccggaat
1201 ggcactgcaa gtgccctctt gcacatagat gagtctgctg gcctcggcag actggctaaa
1261 caaaaaccaa agaaaaggag aagacctgat tccaggcagt accaaacagc aataattatt
1321 ggccctgatg gacatccttt gactgtctat ccttgcatga tttgtgggaa gaagtttaag
1381 tcgagaggtt ttttgaaaag gcacatgaaa aaccatcccg aacaccttgc caagaagaaa
1441 taccgctgta ctgactgtga ttacactacc aacaagaaga taagtttaca caaccacctg
1501 gagagccaca agctgaccag caaggcagag aaggccattg aatgcgatga gtgtgggaag
1561 catttctctc atgcaggggc tttgtttact cacaaaatgg tgcataagga aaaaggagcc
1621 aacaaaatgc acaagtgtaa attctgtgaa tacgagacag ctgaacaagg gttattgaat
1681 cgccacctct tggcagtcca cagcaagaac tttcctcata tttgtgtgga gtgtggtaag
1741 ggttttcgtc acccgtcaga gctcaaaaag cacatgagaa tccatactgg ggagaagccg
1801 taccaatgcc agtactgcga atataggtct gcagactctt ctaacttgaa aacgcatgtc
1861 aaaactaagc atagtaaaga gatgccattc aagtgtgaca tttgtcttct gactttctcg
1921 gataccaaag aggtgcagca acatgctctt atccaccaag aaagcaaaac acaccagtgt
1981 ttgcattgcg accacaagag ttcgaactca agtgatttga aacgacacat aatttcagtt
2041 cacacgaaag actaccccca taagtgtgac atgtgtgata aaggctttca caggccttca
2101 gaactcaaga aacacgtggc tgcccacaag ggcaaaaaaa tgcaccagtg tagacattgt
2161 gactttaaga ttgcagatcc atttgttcta agtcgccata ttctctcagt tcacacaaag
2221 gatcttccat ttaggtgcaa gagatgtaga aagggattta ggcaacagag tgagcttaaa
2281 aagcatatga agacacacag tggcaggaaa gtgtatcagt gtgagtactg tgagtatagc
2341 actacagatg cctcaggctt taaacggcac gttatttcca ttcacacgaa agactatcct
2401 caccggtgtg agtactgcaa gaaaggcttc cgaagacctt cagaaaagaa ccagcacata
2461 atgcgacatc ataaagaagt tggcctgccc taacaatact tctacagaac gtttgtagag
2521 atattggcct tgaagcagaa aattcatttt aaagccaatc agtctcattc acatacaata
2581 ctgtatattg atttatgctg tgtacaaata gaattattac ttctagttga ctttttttta
2641 aatatacatt ttgctcagta gtgtgttctg aattctattc agtttgttta ataaataggg
2701 aaaactggca acatgctagt tacttttaat aaagtaatcc ctgattctat accgaagttt
2761 tatatcttag aattttatat ttatttaaat atttaccttg cttaccttga tggtactctt
2821 ctaagaccat taacttaagg taactttata ttggtaactc tgaaagtatt catgttgact
2881 catttttttc cccatacatt tctcacaata aaattgtcag agacatctac taatataaat
2941 gggagatttt acagtcaggt ctaattatca taacatggaa gtcatttact tgtcttgctt
3001 aatattttca gaccacttga cagtgaaagt ttccatttga gctgttgcgt ccctggcttt
3061 gctgagtaaa gagcagtggc tgggttcgtg tttacttttc aaatatactt ccttttcggc
3121 tttctttgga ttatttacat cttttgtcca gcgtagcaaa cttttagaaa accttattga
3181 aaaactgtgc ttgctcatgt tgtattttga ttattctgtc tgtgcggctt catcttggaa
3241 tggttgtgtg ctacaaatga cacttactga ggactgcatt ttggaatctc ctagaggtaa
3301 ctcatggctt ataggatctt ttgcaacttt atgtatgtaa atgtaccctg aattatatat
3361 atacacatat atatcatgta cctgtgtgta ttgcttattt tacatattta tacacacaac
3421 cccaagtagt agttgtttaa aatctataat gaaaagtatt aaatttacaa taacatgaaa
3481 gatccaggga tgcatgagag agcattttgt aagtcatgct cttcagagag actactcagg
3541 tgaagaatta gaaggaaaat aaggacacta gtatttttaa agagtaaaga tattttcttt
3601 taaatatctt tggtaattga aacatagagg ttaagatgtt tctaggtaga atgttttcat
3661 acaatttcac ctccatgtct ttatgttttt ctgaaaagca aatgagtatc cagacatgac
3721 tcccacagtt ctctttgaga agcctgagag ggaactctgt cttacctagt gagggggatg
3781 gaaaagaagt gatggctctg tggaccagag aacgggtgct aattatgact tcacactcgg
3841 caagttcagg ctgatctgtt atttctcagt tacagttagc aaactttaaa aacttaacac
3901 tcaagttggc tttgattaaa aggtaaagat gtgttttaag tggataagga aagtctgagg
3961 ccttatttgg aacatcacta agtcttccac aaggtttttt gtttgtttgt tttttttttg
4021 ttgttttttt tttcttaaga cggagtcttg ctctgttgcc caggctggac tgcagtggtg
4081 tgatcactgc aaacctctgc agctcactgc aacctctgct tcctgggttc aagcaattat
4141 ctgcctcagc ctctcgagta gctgggatta caggcgccca ccaccacgcc cggctaattt
4201 tttgtatttt taatagagat ggggtttcac catcttggcc aggctggtct tgaaccctga
4261 cctcgtgatc cacctgcctc ggccttccat agtgctgggt ttacaggcgt gagccaccgt
4321 gcccagacac cacataggtc tgaatcagtg tcatacattc ataaaacaaa ctcggttaat
4381 tagaacttgg ttatgttaag acgaatctgg gagaacagaa aacagttttt ggggtccctt
4441 cagttggcta ttggtccgta tgcatctagc acattgtagg agatttagaa attgtcttcc
4501 cacccgatag ctgccttgtc acctcattat ggtgctccat cccctgtgtg cttaggtttt
4561 tacctttcat ctttctcttt gccattgatg tttgtattca agagttatat ttttagggtt
4621 agaaatcaaa atatttggtg tttggcaaac ctctgaagtg ctagactgat ttagtctagt
4681 tttaaaccaa gtgctttagg caggtgtgaa ctccagccca aatgccagtc aaagtcaagg
4741 catgggtttt cctagcctat cttataggaa attcctgtac cttcttggcc cccataatgt
4801 gttttttttt tttttttttt ttaaaactaa cttacaattt tgtgatccgt gattcattgc
4861 cctgcgattc ttgaaagctc tgtctgtttt tttgtgagaa cctttaaaat ctcccttaat
4921 ttttattttc ccagaaataa tgtaaaaaca cttaaatgaa agtggaaatg tattaatttt
4981 aaatcctata aaattaatac agaaaatata aatgattggg tcatttaact atattttttt
5041 aaataaactg aaagataaag aacacaacac ttcacacatt ttatatttct cttacatact
5101 ccggaatcat acacagttct ttttaaagca caacattaaa acctttaaaa ggtatttaag
5161 ggtttggtca agtgaatatg ataaaacata cttgtctgta taaagagaaa atgaaattgt
5221 agtcactgtt atgtactgac attagttaca acctagtttt aattcttaaa acattttgat
5281 tagcaaagct aaaaaaaaat ggatgtttca gttaaatgtt ttaaagaggt acagattttt
5341 acaaggacat aatataagtt attgttctgt agaaatatcc tattaaatat tgtatgtccc
5401 tccctctgta cactttgtaa agaaagtaaa atacataaaa acaaaatcat atagggatgt
5461 gtgacattat tgtaattgtg tacttgagaa taacgtgcaa aaataaaaat cagaatattt
5521 tcctgtt
//