LOCUS X59738 2088 bp mRNA linear HUM 18-APR-2005
DEFINITION Human ZFX mRNA for put. transcription activator, isoform 1.
ACCESSION X59738 X17312
VERSION X59738.1
KEYWORDS sex determination; transcription activator; ZFX gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2088)
AUTHORS Schneider-Gadicke A., Beer-Romero P., Brown L., Mardon G., Luoh S.,
Page D.C.
TITLE Putative transcription activator with alternative isoforms encoded
by human ZFX gene
JOURNAL Nature 342(6250), 708-711(1989).
PUBMED 2512506
FEATURES Location/Qualifiers
source 1..2088
/db_xref="H-InvDB:HIT000322339"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..2088
/gene="ZFX"
/note="alternatively spliced isoform 1"
/experiment="experimental evidence, no additional details
recorded"
CDS 192..1919
/gene="ZFX"
/product="ZFX product, isoform 1"
/note="alternatively spliced isoform 1"
/db_xref="GOA:P17010"
/db_xref="H-InvDB:HIT000322339.14"
/db_xref="HGNC:HGNC:12869"
/db_xref="InterPro:IPR006794"
/db_xref="InterPro:IPR013087"
/db_xref="InterPro:IPR036236"
/db_xref="UniProtKB/Swiss-Prot:P17010"
/protein_id="CAA42416.1"
/translation="MTMDTESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVE
SEPENDHGVELLDQNSSIRVPREKMVYMTVNDSQPEDEDLNVAEIADEVYMEVIVGEE
DAAAAGHAPVHEQQMDDNEIKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGL
GRLAKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHP
EHLAKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTH
KMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELK
KHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQ
HALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKH
VAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHM
KTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIM
RHHKEVGLP"
BASE COUNT 647 a 458 c 488 g 495 t
ORIGIN
1 cggggagctg ggccgctttt tgtcagctcc gagctcggcc cctcctccct ccctccgccc
61 gccccaccag ccggagcccg gcccagtgct ccagagaaag gccggcctgc agcacccgcc
121 accgtcgcgg ccgcccgcaa cgtccgtccg tggatgatgc tggaaaaata gaacacgatg
181 gttcttctgg aatgaccatg gacacagagt cggaaattga tccttgtaaa gtggatggca
241 cttgccctga ggtcatcaag gtgtacattt ttaaagctga ccctggagaa gatgacttag
301 gtggaactgt agacattgtg gagagtgagc ctgagaatga tcatggagtt gaactgcttg
361 atcagaacag cagtattcgt gttcccaggg aaaagatggt ttatatgact gtcaatgact
421 ctcagccaga agatgaagat ttaaatgttg ctgaaatcgc tgacgaagtt tatatggaag
481 tgatcgtagg agaggaggat gctgcagcag caggacacgc gccggtgcac gagcagcaaa
541 tggatgacaa tgaaatcaaa accttcatgc cgattgcatg ggcagcagct tatggtaata
601 attctgatgg aattgaaaac cggaatggca ctgcaagtgc cctcttgcac atagatgagt
661 ctgctggcct cggcagactg gctaaacaaa aaccaaagaa aaggagaaga cctgattcca
721 ggcagtacca aacagcaata attattggcc ctgatggaca tcctttgact gtctatcctt
781 gcatgatttg tgggaagaag tttaagtcga gaggtttttt gaaaaggcac atgaaaaacc
841 atcccgaaca ccttgccaag aagaaatacc gctgtactga ctgtgattac actaccaaca
901 agaagataag tttacacaac cacctggaga gccacaagct gaccagcaag gcagagaagg
961 ccattgaatg cgatgagtgt gggaagcatt tctctcatgc aggggctttg tttactcaca
1021 aaatggtgca taaggaaaaa ggagccaaca aaatgcacaa gtgtaaattc tgtgaatacg
1081 agacagctga acaagggtta ttgaatcgcc acctcttggc agtccacagc aagaactttc
1141 ctcatatttg tgtggagtgt ggtaagggtt ttcgtcaccc gtcagagctc aaaaagcaca
1201 tgagaatcca tactggggag aagccgtacc aatgccagta ctgcgaatat aggtctgcag
1261 actcttctaa cttgaaaacg catgtcaaaa ctaagcatag taaagagatg ccattcaagt
1321 gtgacatttg tcttctgact ttctcggata ccaaagaggt gcagcaacat gctcttatcc
1381 accaagaaag caaaacacac cagtgtttgc attgcgacca caagagttcg aactcaagtg
1441 atttgaaacg acacataatt tcagttcaca cgaaagacta cccccataag tgtgacatgt
1501 gtgataaagg ctttcacagg ccttcagaac tcaagaaaca cgtggctgcc cacaagggca
1561 aaaaaatgca ccagtgtaga cattgtgact ttaagattgc agatccattt gttctaagtc
1621 gccatattct ctcagttcac acaaaggatc ttccatttag gtgcaagaga tgtagaaagg
1681 gatttaggca acagagtgag cttaaaaagc atatgaagac acacagtggc aggaaagtgt
1741 atcagtgtga gtactgtgag tatagcacta cagatgcctc aggctttaaa cggcacgtta
1801 tttccattca cacgaaagac tatcctcacc ggtgtgagta ctgcaagaaa ggcttccgaa
1861 gaccttcaga aaagaaccag cacataatgc gacatcataa agaagttggc ctgccctaac
1921 aatacttcta cagaacgttt gtagagatat tggccttgaa gcagaaaatt cattttaaag
1981 ccaatcagtc tcattcacat acaatactgt atattgattt atgctgtgta caaatagaat
2041 tattacttct agttgacttt tttttaaata tacattttgc tcagtagt
//