LOCUS X59618 2500 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens RR2 mRNA for small subunit ribonucleotide reductase.
ACCESSION X59618 S40302
VERSION X59618.1
KEYWORDS DNA synthesis enzyme; holoenzyme; ribonucleotide reductase; small
subunit ribonucleotide reductase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2500)
AUTHORS Mes-Masson A.M.
JOURNAL Submitted (23-APR-1991) to the INSDC. A.M. Mes-Masson,
Biotechnology Research Institute, 6100 Royalmount, Montreal,
Quebec, H4P 2R2, CANADA
REFERENCE 2 (bases 1 to 2500)
AUTHORS Pavloff N., Rivard D., Masson S., Shen S.H., Mes-Masson A.M.
TITLE Sequence analysis of the large and small subunits of human
ribonucleotide reductase
JOURNAL DNA Seq 2(4), 227-234(1992).
PUBMED 1627826
COMMENT See also X59617
FEATURES Location/Qualifiers
source 1..2500
/db_xref="H-InvDB:HIT000322329"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="Clonetech 5'stretch lambda"
/tissue_type="breast carcinoma"
/db_xref="taxon:9606"
CDS 195..1364
/gene="RR2"
/product="small subunit ribonucleotide reductase"
/db_xref="GOA:P31350"
/db_xref="H-InvDB:HIT000322329.14"
/db_xref="HGNC:HGNC:10452"
/db_xref="InterPro:IPR000358"
/db_xref="InterPro:IPR009078"
/db_xref="InterPro:IPR012348"
/db_xref="InterPro:IPR030475"
/db_xref="InterPro:IPR033909"
/db_xref="PDB:2UW2"
/db_xref="PDB:3OLJ"
/db_xref="PDB:3VPM"
/db_xref="PDB:3VPN"
/db_xref="PDB:3VPO"
/db_xref="UniProtKB/Swiss-Prot:P31350"
/protein_id="CAA42181.1"
/translation="MLSLRVPLAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLA
SKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFW
TAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARC
FYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKE
ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLM
FKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLE
LGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF"
regulatory 1755..1760
/regulatory_class="polyA_signal_sequence"
polyA_site 2475
BASE COUNT 679 a 522 c 595 g 704 t
ORIGIN
1 cccaggcgca gccaatggga agggtcggag gcatggcaca gccaatggga agggccgggg
61 caccaaagcc aatgggaagg gccgggagcg cgcggcgcgg gagatttaaa ggctgctgga
121 gtgaggggtc gcccgtgcac cctgtcccag ccgtcctgtc ctggctgctc gctctgcttc
181 gctgcgcctc cactatgctc tccctccgtg tcccgctcgc gcccatcacg gacccgcagc
241 agctgcagct ctcgccgctg aaggggctca gcttggtcga caaggagaac acgccgccgg
301 ccctgagcgg gacccgcgtc ctggccagca agaccgcgag gaggatcttc caggagccca
361 cggagccgaa aactaaagca gctgcccccg gcgtggagga tgagccgctg ctgagagaaa
421 acccccgccg ctttgtcatc ttccccatcg agtaccatga tatctggcag atgtataaga
481 aggcagaggc ttccttttgg accgccgagg aggttgacct ctccaaggac attcagcact
541 gggaatccct gaaacccgag gagagatatt ttatatccca tgttctggct ttctttgcag
601 caagcgatgg catagtaaat gaaaacttgg tggagcgatt tagccaagaa gttcagatta
661 cagaagcccg ctgtttctat ggcttccaaa ttgccatgga aaacatacat tctgaaatgt
721 atagtcttct tattgacact tacataaaag atcccaaaga aagggaattt ctcttcaatg
781 ccattgaaac gatgccttgt gtcaagaaga aggcagactg ggccttgcgc tggattgggg
841 acaaagaggc tacctatggt gaacgtgttg tagcctttgc tgcagtggaa ggcattttct
901 tttccggttc ttttgcgtcg atattctggc tcaagaaacg aggactgatg cctggcctca
961 cattttctaa tgaacttatt agcagagatg agggtttaca ctgtgatttt gcttgcctga
1021 tgttcaaaca cctggtacac aaaccatcgg aggagagagt aagagaaata attatcaatg
1081 ctgttcggat agaacaggag ttcctcactg aggccttgcc tgtgaagctc attgggatga
1141 attgcactct aatgaagcaa tacattgagt ttgtggcaga cagacttatg ctggaactgg
1201 gttttagcaa ggttttcaga gtagagaacc catttgactt tatggagaat atttcactgg
1261 aaggaaagac taacttcttt gagaagagag taggcgagta tcagaggatg ggagtgatgt
1321 caagtccaac agagaattct tttaccttgg atgctgactt ctaaatgaac tgaagatgtg
1381 cccttacttg gctgattttt tttttccatc tcataagaaa aatcagctga agtgttacca
1441 actagccaca ccatgaattg tccgtaatgt tcattaacag catctttaaa actgtgtagc
1501 tacctcacaa ccagtcctgt ctgtttatag tgctggtagt atcacctttt gccagaaggc
1561 ctggctggct gtgacttacc atagcagtga caatggcagt cttggcttta aagtgagggg
1621 tgacccttta gtgagcttag cacagcggga ttaaacagtc ctttaaccag cacagccagt
1681 taaaagatgc agcctcactg cttcaacgca gattttaatg tttacttaaa tataaacctg
1741 gcactttaca aacaaataaa cattgttttg tactcacggc ggcgataata gcttgattta
1801 tttggtttct acaccaaata cattctcctg accactaatg ggagccaatt cacaattcac
1861 taagtgacta aagtaagtta aacttgtgta gactaagcat gtaattttta agttttattt
1921 taatgaatta aaatatttgt taaccaactt taaagtcagt cctgtgtata cctagatatt
1981 agtcagttgg tgccagatag aagacaggtt gtgtttttat cctgtggctt gtgtagtgtc
2041 ctgggattct ctgccccctc tgagtagagt gttgtgggat aaaggaatct ctcagggcaa
2101 ggagcttctt aagttaaatc actagaaatt taggggtgat ctgggccttc atatgtgtga
2161 gaagccgttt cattttattt ctcactgtat tttcctcaac gtctggttga tgagaaaaaa
2221 ttcttgaaga gttttcatat gtgggagcta aggtagtatt gtaaaatttc aagtcatcct
2281 taaacaaaat gatccaccta agatcttgcc cctgttaagt ggtgaaatca actagaggtg
2341 gttcctacaa gttgttcatt ctagttttgt ttggtgtaag taggttgtgt gagttaattc
2401 atttatattt actatgtctg ttaaatcaga aattttttat tatctatgtt cttctagatt
2461 ttacctgtag ttcataaaaa aaaaaaaaaa aaaaaaaaaa
//