LOCUS       X59445                   969 bp    mRNA    linear   HUM 27-FEB-1992
DEFINITION  H.sapiens mRNA for colon carcinoma Manganese Superoxide Dismutase.
ACCESSION   X59445
VERSION     X59445.1
KEYWORDS    manganese superoxide dismutase.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 969)
  AUTHORS   Clair D.K.S., Holland J.C.
  TITLE     Complementary DNA encoding human colon cancer manganese superoxide
            dismutase and the expression of its gene in human cells.
  JOURNAL   Cancer Res. 51(3), 939-943(1991).
   PUBMED   1988135
FEATURES             Location/Qualifiers
     source          1..969
                     /db_xref="H-InvDB:HIT000322322"
                     /organism="Homo sapiens"
                     /isolate="HT-29"
                     /mol_type="mRNA"
                     /clone_lib="cDNA"
                     /tissue_type="colon carcinoma"
                     /db_xref="taxon:9606"
     sig_peptide     61..132
                     /product="manganese superoxide dismutase (MnSOD)"
     CDS             61..729
                     /product="manganese superoxide dismutase (MnSOD)"
                     /db_xref="GOA:P04179"
                     /db_xref="H-InvDB:HIT000322322.12"
                     /db_xref="HGNC:HGNC:11180"
                     /db_xref="InterPro:IPR001189"
                     /db_xref="InterPro:IPR019831"
                     /db_xref="InterPro:IPR019832"
                     /db_xref="InterPro:IPR019833"
                     /db_xref="InterPro:IPR036314"
                     /db_xref="InterPro:IPR036324"
                     /db_xref="PDB:1AP5"
                     /db_xref="PDB:1AP6"
                     /db_xref="PDB:1EM1"
                     /db_xref="PDB:1JA8"
                     /db_xref="PDB:1LUV"
                     /db_xref="PDB:1LUW"
                     /db_xref="PDB:1MSD"
                     /db_xref="PDB:1N0J"
                     /db_xref="PDB:1N0N"
                     /db_xref="PDB:1PL4"
                     /db_xref="PDB:1PM9"
                     /db_xref="PDB:1QNM"
                     /db_xref="PDB:1SZX"
                     /db_xref="PDB:1VAR"
                     /db_xref="PDB:1XDC"
                     /db_xref="PDB:1XIL"
                     /db_xref="PDB:1ZSP"
                     /db_xref="PDB:1ZTE"
                     /db_xref="PDB:1ZUQ"
                     /db_xref="PDB:2ADP"
                     /db_xref="PDB:2ADQ"
                     /db_xref="PDB:2GDS"
                     /db_xref="PDB:2P4K"
                     /db_xref="PDB:2QKA"
                     /db_xref="PDB:2QKC"
                     /db_xref="PDB:3C3S"
                     /db_xref="PDB:3C3T"
                     /db_xref="PDB:5GXO"
                     /db_xref="PDB:5T30"
                     /db_xref="PDB:5VF9"
                     /db_xref="UniProtKB/Swiss-Prot:P04179"
                     /protein_id="CAA42066.1"
                     /translation="MLSRAVCGTSRQLAPALGYLGSRQKHSLPDLPYDYGALEPHINA
                     QIMQLHHSKHHAAYVNNLNVNEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFW
                     TNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQ
                     IAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYM
                     ACKK"
     mat_peptide     133..726
                     /product="manganese superoxide dismutase (MnSOD)"
     polyA_site      942
BASE COUNT          277 a          208 c          244 g          240 t
ORIGIN      
        1 tggcttcggc agcggcttca gcagatcggc ggcatcagcg gtagcaccag cactagcagc
       61 atgttgagcc gggcagtgtg cggcaccagc aggcagctgg ctccggcttt ggggtatctg
      121 ggctccaggc agaagcacag cctccccgac ctgccctacg actacggcgc cctggaacct
      181 cacatcaacg cgcagatcat gcagctgcac cacagcaagc accacgcggc ctacgtgaac
      241 aacctgaacg tcaacgagga gaagtaccag gaggcgttgg ccaagggaga tgttacagcc
      301 cagatagctc ttcagcctgc actgaagttc aatggtggtg gtcatatcaa tcatagcatt
      361 ttctggacaa acctcagccc taacggtggt ggagaaccca aaggggagtt gctggaagcc
      421 atcaaacgtg actttggttc ctttgacaag tttaaggaga agctgacggc tgcatctgtt
      481 ggtgtccaag gctcaggttg gggttggctt ggtttcaata aggaacgggg acacttacaa
      541 attgctgctt gtccaaatca ggatccactg caaggaacaa caggccttat tccactgctg
      601 gggattgatg tgtgggagca cgcttactac cttcagtata aaaatgtcag gcctgattat
      661 ctaaaagcta tttggaatgt aatcaactgg gagaatgtaa ctgaaagata catggcttgc
      721 aaaaagtaaa ccacgatcgt tatgctgagt atgttaagct ctttatgact gtttttgtag
      781 tggtatagag tactgcagaa tacagtaagc tgctctattg tagcatttct tgatgttgct
      841 tagtcactta tttcataaac aacttaatgt tctgaataat ttcttactaa acattttgtt
      901 attgggcaag tgattgaaaa tagtaaatgc tttgtgtgat tgaaaaaaaa aaaaaaaaaa
      961 aaaaaaaaa
//