LOCUS X58531 7979 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human LAMA mRNA for laminin A chain, partial cds.
ACCESSION X58531
VERSION X58531.1
KEYWORDS LAMA gene; laminin A chain.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7979)
AUTHORS Tryggvason K.
JOURNAL Submitted (21-MAR-1991) to the INSDC. K. Tryggvason, Biocenter and
Dept of Biochemistry, University of Oulu, SF-90570 Oulu, FINLAND
REFERENCE 2
AUTHORS Nissinen M., Vuolteenaho R., Boot-Handford R., Kallunki P.,
Tryggvason K.
TITLE Primary structure of the human laminin A chain: Limited expression
in human tissues
JOURNAL Biochem. J. 276, 369-379(1991).
PUBMED 2049067
FEATURES Location/Qualifiers
source 1..7979
/db_xref="H-InvDB:HIT000322237"
/organism="Homo sapiens"
/chromosome="18p11.3"
/mol_type="mRNA"
/cell_line="JAR"
/cell_type="choriocarcinoma"
/db_xref="taxon:9606"
CDS 95..>7979
/gene="LAMA"
/product="laminin A chain"
/db_xref="GOA:P25391"
/db_xref="H-InvDB:HIT000322237.14"
/db_xref="HGNC:HGNC:6481"
/db_xref="InterPro:IPR000034"
/db_xref="InterPro:IPR000742"
/db_xref="InterPro:IPR001791"
/db_xref="InterPro:IPR002049"
/db_xref="InterPro:IPR008211"
/db_xref="InterPro:IPR009254"
/db_xref="InterPro:IPR010307"
/db_xref="InterPro:IPR013320"
/db_xref="InterPro:IPR038684"
/db_xref="UniProtKB/Swiss-Prot:P25391"
/protein_id="CAA41418.1"
/translation="MRGGVLLVLLLCVAAQCRQRGLFPAILNLASNAHISTNATCGEK
GPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGR
EYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECL
SRYNITPRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEF
TSARYIRLRFERIRTLNADLMTLSHREPKELDPMLPRRYYYSIKDISVGGMCICYGHA
SSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAK
DCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDE
PCRPCNCDPVGSLSSVCIKDDLHSDLENGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT
CVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGV
SDVCSSLSWPLGQVNSMSGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPK
YYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAE
GLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLMTVLANVTHLLIRATYNSAKMAL
YRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQ
PCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIA
SNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVD
PSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVC
HLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCV
PGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECED
GHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACVQCSLGYRDFPDCV
PCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLG
CSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLD
AATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKG
GRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYI
LIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAP
GYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTS
GYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSS
YYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETD
CVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENM
QKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAVAIERLQMSI
TEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAE
DLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLM
VNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLL
LWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHATEFQRLADVLYSGLENIRNVSLNAT
SAAYVHYNIQSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNL
SRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPEGIRDKGAKTKELAT
SASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDV
EIQAKVLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSADRDCIRAYQP
QISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLE
FPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLM
FVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFGSSQNEDP
SFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVK
VMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGA
SSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISRSTFDLLRNSYGVRKG
CLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSSGIILAALGGDVEKRGDRE
EAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIIT
VQLDENNPVEMKLGTLVESRTINVSNLYVGGI"
sig_peptide 95..145
/gene="LAMA"
/product="laminin A chain"
mat_peptide 146..>7979
/gene="LAMA"
/product="laminin A chain"
BASE COUNT 2052 a 1958 c 2143 g 1826 t
ORIGIN
1 cggggccagg gcagcgcgga ctcgcgtccc gcggagcgtt ccaggcgggc gcgcggcttt
61 ctccccagac ccaccgagtg gcggcggagg cgagatgcgc gggggcgtgc tcctggtctt
121 gctgctgtgt gtcgccgcgc agtgccggca gagaggcctg tttcctgcca ttctcaatct
181 tgccagcaat gctcacatca gcaccaatgc cacctgtggc gagaaggggc cggagatgtt
241 ctgcaaactt gtggagcatg tgccaggtcg gcccgtccga aacccacagt gccggatctg
301 tgatggcaac agcgcaaacc ccagagaacg ccatccaata tcacatgcca tagatggcac
361 caataactgg tggcaaagtc ccagcattca gaatgggaga gaatatcact gggtcacaat
421 cactctggac ttaagacagg tctttcaagt tgcatatgtc atcattaaag ctgccaatgc
481 ccctcgacct ggaaactgga ttttggagcg ttctctggat ggcaccacgt tcagcccctg
541 gcagtattat gcagtcagcg actcagagtg tttgtctcgt tacaatataa ctccaagacg
601 agggccaccc acctacaggg ctgatgatga agtgatctgc acctcctatt attccagatt
661 ggtgccactt gagcatggag agattcatac atcactcatc aatggcagac caagcgctga
721 cgatctttca cccaagttgt tggaattcac ttctgcacga tatattcgcc ttcgcttcga
781 acgcattaga acgctcaatg cagatctcat gacccttagc caccgggaac ctaaagaact
841 ggatcctatg ttaccaagac gctattatta ttcaataaag gacatttctg ttggaggcat
901 gtgtatctgc tatggccatg ctagtagctg cccatgggat gaaactacaa agaaactgca
961 gtgtcaatgt gagcataata cttgcgggga gagctgtaac aggtgctgtc ctgggtacca
1021 tcagcagccc tggaggccgg gaaccgtgtc ctccggcaat acatgtgaag catgtaattg
1081 tcacaataaa gccaaagact gttactatga tgaaagtgtt gcaaagcaga agaaaagttt
1141 gaatactgct ggacagttca gaggaggagg ggtttgcata aattgcttgc agaacaccat
1201 gggaatcaac tgtgaaacct gtattgatgg atattataga ccacacaaag tgtctcctta
1261 tgaggatgag ccttgccgcc cctgtaattg tgaccctgtg gggtccctca gttctgtctg
1321 tattaaggat gacctccatt ctgacttaga gaatgggaag cagccaggtc agtgcccatg
1381 taaggaaggt tatacaggag aaaaatgtga tcgctgccaa cttggctata aggattaccc
1441 gacctgtgtc tcctgtgggt gcaacccagt gggcagtgcc agtgatgagc cctgcacagg
1501 gccctgtgtt tgtaaggaaa acgttgaggg gaaggcctgt gatcgctgca agccaggatt
1561 ctataacttg aaggaaaaaa acccccgggg ctgctccgag tgcttctgct ttggcgtttc
1621 tgatgtctgc agcagcctct cttggcctct tggtcaggta aacagtatgt ccgggtggct
1681 ggtcaccgac ttgatcagtc ccaggaagat cccgtctcag caagatgcac taggcgggcg
1741 ccatcaggtc agcatcaaca acaccgcggt catgcagaga ctggctccca agtactactg
1801 ggcagccccc gaggcctacc ttggaaataa gctgactgcg tttggcggat tcctgaaata
1861 cacggtgtcc tacgatattc cggtagagac ggtagacagt aacctcatgt cgcatgctga
1921 cgtcatcatt aagggaaacg gactcacttt aagcacacag gctgagggtc tgtcattgca
1981 gccttatgaa gagtacctaa acgtggttag acttgtgcct gaaaacttcc aagattttca
2041 cagcaaaagg cagattgatc gtgaccagct gatgactgtc cttgccaatg tgacacatct
2101 tttgatcaga gccacctaca attctgcaaa aatggctctt tacaggttgg agtccgtctc
2161 tctggacata gccagctcta atgccatcga cctggtggtg gctgctgatg tggagcactg
2221 tgaatgtccg caaggctaca cagggacctc ctgtgagtcg tgcctctctg gctattaccg
2281 cgtggatgga atactctttg gaggaatttg tcaaccctgt gaatgccacg gccatgcagc
2341 tgagtgtaat gttcacggcg tttgcattgc gtgtgcgcac aacaccaccg gcgtccactg
2401 tgagcagtgc ttgcccggct tctacgggga gccttcccga gggacacctg gggactgcca
2461 gccctgcgcc tgccctctca ccatagcctc caacaatttc agccccacct gccacctcaa
2521 tgatggagat gaagtggtct gtgactggtg tgccccgggc tactcaggag cttggtgtga
2581 gagatgcgca gatggttact atggaaaccc aacagtgcct ggcgaatctt gtgttccctg
2641 tgactgcagc ggcaacgtgg acccctcgga ggctggtcac tgtgactcag tcaccgggga
2701 gtgcctgaag tgcctgggga acacagatgg cgcccactgt gaaaggtgcg ctgacgggtt
2761 ctatggggac gctgtgacag ccaagaactg ccgcgcctgt gaatgccatg tgaaaggctc
2821 ccattctgcc gtgtgccatc ttgagaccgg gctctgtgac tgcaaaccaa acgtgactgg
2881 acagcagtgt gaccagtgct tgcatggcta ttatgggctg gactcaggcc atggctgccg
2941 gccctgcaac tgcagcgtgg caggctccgt gtcagatggc tgcacggatg aaggccagtg
3001 tcactgtgtc ccaggtgtgg cagggaaaag gtgtgacagg tgtgcccatg gcttctacgc
3061 ctaccaggat ggtagctgta caccctgtga ctgcccacac actcagaata cctgcgaccc
3121 agaaactgga gagtgtgtct gcccccctca cacacagggt gtgaagtgtg aagaatgtga
3181 ggatgggcac tggggctacg atgcggaggt ggggtgccag gcctgcaatt gcagtctcgt
3241 ggggtcgact catcatcggt gcgatgtggt caccggccat tgccagtgca agtcaaaatt
3301 tggtggccgg gcctgcgtac agtgttcctt gggttacaga gactttcccg actgtgttcc
3361 ctgtgactgt gacctgaggg ggacgtcggg ggacgcctgc aacctggagc agggtctctg
3421 cggctgtgtg gaggaaaccg gggcctgccc ttgcaaggaa aatgtctttg gtcctcagtg
3481 caacgaatgt cgagagggca ccttcgctct ccgcgcagac aaccccctgg gctgcagccc
3541 gtgcttctgc tccgggctgt cccacctctg ctcagagctg gaggactacg tgaggacccc
3601 agtaacgctg ggctccgatc agcctcttct gcgtgtggtt tctcagagta acttgagggg
3661 cacgactgag ggggtttact accaggcccc cgacttcctg ctggatgccg ccaccgtccg
3721 gcagcacatc cgtgcagagc cgttttactg gcggctgccg cagcagttcc aaggagacca
3781 gctcatggcc tatggtggca aactgaagta cagcgtggcc ttctattctt tggatggcgt
3841 cggcacctcc aattttgagc ctcaagttct catcaaaggt ggtcggatca gaaagcaagt
3901 catttacatg gatgcaccag ccccagagaa tggagtgaga caggaacaag aagtagcaat
3961 gagagagaat ttttggaaat attttaactc tgtttctgaa aaacctgtca cgcgagagga
4021 ttttatgtct gtcctcagcg atattgagta catcctcatc aaggcatcgt atggtcaagg
4081 attacagcag agcagaatct cagacatttc aatggaggtt ggcagaaagg ctgaaaagct
4141 gcacccagaa gaagaggttg catctctttt agagaattgt gtctgtcctc ctggcactgt
4201 gggattctca tgtcaggact gcgcccctgg gtaccacaga gggaagctcc cagcagggag
4261 tgacagggga ccacgccctc tggttgctcc ttgtgttccc tgcagttgca acaaccacag
4321 tgacacctgt gaccccaaca ccgggaagtg tctgaactgt ggcgataaca cagcaggtga
4381 ccattgtgat gtgtgtactt ctggctacta cgggaaggtg actggctcag caagtgactg
4441 tgctctgtgt gcctgtcctc acagccctcc tgccagtttt agtcccactt gtgtcttgga
4501 aggggaccac gatttccgtt gtgacgcctg tctcctgggc tatgaaggaa aacactgtga
4561 aaggtgctcc tcaagctatt atgggaaccc tcaaacacca ggtggcagtt gccagaagtg
4621 tgactgcaac ccgcacggct ctgtccacgg tgactgtgac cgcacatctg ggcagtgcgt
4681 ttgcaggctg ggggcctcgg ggctccggtg cgatgagtgt gaaccgaggc acattctgat
4741 ggaaacagat tgtgtttcct gtgatgatga gtgtgtaggt gtgctgctga atgacttgga
4801 tgagattggt gatgccgttc tttctctgaa cctcactggc attatccctg tcccatatgg
4861 aattttgtca aacctggaaa atacaactaa atatctccag gaatctttat taaaagaaaa
4921 tatgcaaaag gacctgggaa aaattaagct tgaaggtgtt gcagaagaaa cggacaacct
4981 gcaaaagaag ctcactagga tgttagcgag tacccaaaag gtgaataggg caactgagag
5041 aatcttcaag gagagtcaag acctggccgt agccattgag aggctgcaga tgagcatcac
5101 agaaattatg gaaaagacaa ctttaaatca gactttggat gaagatttcc tactacccaa
5161 ttctactctt cagaacatgc aacagaatgg tacatctttg ctagaaatca tgcagataag
5221 agacttcaca cagttgcacc aaaatgccac ccttgaactc aaggctgctg aagatttatt
5281 gtcacaaatt caggaaaatt accagaagcc gctggaagaa ttggaggtat tgaaagaagc
5341 agcaagccat gtcctttcaa agcacaacaa tgaactaaag gcggctgagg cgctcgtgag
5401 ggaagctgag gcaaagatgc aggaaagcaa ccacctgctg ctcatggtca atgctaatct
5461 gagagaattc agtgataaaa agctgcatgt tcaagaagaa caaaatctga cctcagagct
5521 cattgtccaa ggaagaggat tgatagatgc tgctgctgca caaacagatg ctgtacaaga
5581 tgctctagag cacttagagg atcaccagga taagctactt ttatggtctg ccaaaatcag
5641 gcaccacata gatgacctgg tcatgcacat gtcccaaagg aacgcagtcg acctggtcta
5701 cagagctgag gaccatgcca ctgagttcca gagactagca gatgttctgt acagtggcct
5761 tgaaaacatc agaaatgtgt ccctgaatgc caccagtgca gcctatgtcc attacaacat
5821 ccagagcctg attgaagaat cggaggaact ggccagagat gctcacagga ctgtgactga
5881 gacgagcctg ctctcagaat cccttgtttc taacgggaaa gcggccgtgc agcgcagctc
5941 cagatttcta aaagaaggca acaacctcag caggaagctt ccaggtattg cattggaact
6001 gagtgaattg agaaataaga caaacagatt tcaagagaat gctgttgaaa ttaccaggca
6061 aaccaatgaa tcactcttga tacttagagc aattcctgaa ggtataagag acaagggagc
6121 caaaaccaaa gagctggcca cgtctgcaag ccagagcgcg gtgagcacgc tgagggacgt
6181 ggcggggctg agccaggagc tgctgaacac atctgccagc ctgtccaggg tcaacaccac
6241 attacgagag acacaccagc ttctgcagga ctccaccatg gccactctgt tggctggaag
6301 aaaagtcaaa gacgtggaaa ttcaagccaa ggttttgttt gatcggttga agcctttgaa
6361 gatgttagag gagaatctga gcagaaacct atcagaaatt aaactgttga tcagccaggc
6421 ccgcaaacaa gcagcttcta ttaaagtcgc cgtgtctgca gacagagatt gcatccgggc
6481 ctaccagcct cagatttcct ctaccaacta caatacctta acactaaatg ttaagacaca
6541 ggaacccgat aatcttctct tctacctcgg tagcagcacc gcttctgatt tccttgcagt
6601 ggagatgcgg cgagggagag tggccttcct gtgggacctg ggctccgggt ccacacgctt
6661 ggagtttcca gactttccca ttgatgacaa cagatggcac agtatccatg tagccagatt
6721 tggaaacatt ggttcactga gtgtaaagga aatgagctca aatcaaaagt caccaacaaa
6781 aacaagtaaa tcccctggga cagctaatgt tctggatgta aacaattcaa cactcatgtt
6841 tgttggaggt cttggaggac aaatcaagaa atctcctgct gtgaaggtta ctcattttaa
6901 aggctgcttg ggggaggcct tcctgaatgg aaaatccata ggcctatgga actatattga
6961 aagggaaggc aagtgccgtg ggtgcttcgg aagctcccag aatgaagacc cttccttcca
7021 ttttgacggg agtgggtact ctgtcgtgga gaagtcactt ccggctaccg tgacccagat
7081 aatcatgctt tttaatacct tttcacctaa tggacttctt ctctacctgg gttcatacgg
7141 cacaaaagac tttttatcca tcgagctgtt tcgtggcaga gtgaaggtta tgactgacct
7201 gggttcagga cccattaccc ttttgacaga cagacgttat aacaatggaa cctggtacaa
7261 aattgccttc cagcgaaacc ggaagcaagg agtgctagca gttatcgatg cctataacac
7321 cagtaataaa gaaaccaagc agggcgagac tccgggagca tcttctgacc tcaaccgcct
7381 agacaaggac ccgatttatg tgggtggatt accaaggtca agagttgtaa ggagaggtgt
7441 caccaccaaa agctttgtgg gctgcatcaa gaacctggaa atatccagat caacctttga
7501 cttactcaga aattcctatg gagtgagaaa aggctgttta ctggagccca tccggagtgt
7561 tagcttcctg aaaggcggct acattgaatt gccacccaaa tctttgtcac cagaatcaga
7621 atggctggta acatttgcca ccacgaacag cagtggcatc atcctggctg ccctcggcgg
7681 ggatgtggag aagcggggtg atcgtgagga agcacacgtg cccttctttt ccgtcatgct
7741 gatcggaggc aacattgagg tacatgtcaa tcctggggat gggacaggcc tgagaaaagc
7801 tctcctgcac gctcccacgg gtacctgcag tgatggacaa gcgcattcca tctccttggt
7861 caggaatcgg agaattatca ctgtccaatt ggatgagaac aatcctgtgg aaatgaagtt
7921 gggcacatta gtagaaagca ggacgataaa tgtgtccaat ctgtacgtcg ggggaattc
//