LOCUS X58288 4998 bp mRNA linear HUM 21-OCT-2008
DEFINITION H.sapiens hR-PTPu gene for protein tyrosine phosphatase.
ACCESSION X58288
VERSION X58288.1
KEYWORDS hR-PTPu gene; protein tyrosine phosphatase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4998)
AUTHORS Gebbink M.F.B.G.
JOURNAL Submitted (12-JUL-1991) to the INSDC. M.F.B.G. Gebbink, Dutch
Center Inst., Plesmanlaan 121, 1066 CX Amsterdam, THE NETHERLANDS
REFERENCE 2
AUTHORS Gebbink M.F.B.G., Van Etten I., Hateboer G., Suijkerbuijk R.,
Beijersbergen R., Van Kessel A.G., Moolenaar W.H.
TITLE Cloning, expression and chromosomal localization of a new putative
receptor-like protein tyrosine phosphatase
JOURNAL FEBS Lett. 290(1-2), 123-130(1991).
PUBMED 1655529
COMMENT See X58287, X58289 for related sequences
FEATURES Location/Qualifiers
source 1..4998
/db_xref="H-InvDB:HIT000322208"
/organism="Homo sapiens"
/chromosome="18"
/map="18pter-q11"
/mol_type="mRNA"
/clone="mc10, mc12, helapcdc"
/db_xref="taxon:9606"
CDS 1..4359
/gene="hR-PTPu"
/product="protein-tyrosine phosphatase"
/EC_number="3.1.3.48"
/db_xref="GOA:P28827"
/db_xref="H-InvDB:HIT000322208.14"
/db_xref="HGNC:HGNC:9675"
/db_xref="InterPro:IPR000242"
/db_xref="InterPro:IPR000387"
/db_xref="InterPro:IPR000998"
/db_xref="InterPro:IPR003595"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR003961"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013151"
/db_xref="InterPro:IPR013320"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR016130"
/db_xref="InterPro:IPR029021"
/db_xref="InterPro:IPR036116"
/db_xref="InterPro:IPR036179"
/db_xref="PDB:1RPM"
/db_xref="PDB:2C9A"
/db_xref="PDB:2V5Y"
/db_xref="UniProtKB/Swiss-Prot:P28827"
/protein_id="CAA41226.1"
/translation="MRTLGTCLATLAGLLLTAAGETFSGGCLFDEPYSTCGYSQSEGD
DFNWEQVNTLTKPTSDPWMPSGSLMLVNASGRPEGQRAHLLLPQLKENDTHCIDFHYF
VSSKSNSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAELAISTFWPNFYQVIFE
VITSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRL
WLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAEL
VVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVD
STSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVK
SRQITIRWEPFGYNVTRCHSYNLTVHYCYQVGGQEQVREEVSWDTENSHPQHTITNLS
PYTNVSVKLILMNPEGRKESQELIVQTDEDLPGAVPTESIQGSTFEEKIFLQWREPTQ
TYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRAS
TAKGFGPPATNQFTTKISAPSMPAYELETPLNQTDNTVTVMLKPAHSRGAPVSVYQIV
VEEERPRRTKKTTEILKCYPVPIHFQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNK
TYNGYWNTPLLPYKSYRIYFQAASRANGETKIDCVQVATKGAATPKPVPEPEKQTDHT
VKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQ
GTNCDEAFSFMDTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDETHTMASDTSSLV
QSHTYKKREPADVPYQTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQSAP
WDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQ
GPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETE
LLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSA
GPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVF
IHDAILEACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVED
CSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQH
PLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQLCPQYWPENGVHRHGPIQVEFVSADLE
EDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEY
NGGEGPTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLD
QYKFCYEVALEYLNSG"
mRNA 1..4998
/gene="hR-PTPu"
/experiment="experimental evidence, no additional details
recorded"
sig_peptide 1..60
/gene="hR-PTPu"
mat_peptide 61..4356
/gene="hR-PTPu"
/product="protein-tyrosine phosphatase"
/EC_number="3.1.3.48"
BASE COUNT 1416 a 1189 c 1213 g 1176 t
ORIGIN
1 atgaggacac ttgggacttg cctggcgact ttggccggac ttttgctaac tgcggcgggc
61 gagacgttct caggtggctg cctctttgat gagccgtata gcacatgtgg atatagtcaa
121 tctgaaggtg atgacttcaa ttgggagcaa gtgaacacct tgactaaacc gacttctgat
181 ccatggatgc catcaggttc tctcatgctg gtgaatgcct ctgggagacc tgaggggcag
241 agagcccacc tgctcttacc ccaacttaag gaaaatgaca cccactgcat cgattttcac
301 tattttgtgt ccagcaagag taattctcct ccggggttac tcaatgtcta cgtgaaggtc
361 aataacgggc cactggggaa tcctatctgg aatatatctg gagacccaac acgtacatgg
421 aacagggcag aactggccat tagtactttc tggcctaact tttatcaggt gatttttgaa
481 gtgataactt ctggacatca aggctatctc gctatcgatg aggtgaaggt gttaggacat
541 ccatgtacca ggactcctca cttcctgcgg attcagaatg tggaagttaa tgctggccag
601 tttgctacct tccagtgcag tgccatcggc aggaccgtgg caggagacag gctctggtta
661 cagggcattg atgtgcgaga tgctcctctg aaggaaatca aggtgaccag ctcccgacgc
721 ttcattgctt catttaatgt tgtgaatacc accaaacgag atgctggaaa gtaccgctgc
781 atgattcgca ctgaaggagg tgttggaata tcaaactatg cagagttggt agttaaagaa
841 ccacccgttc ctattgcccc acctcagctc gcctctgtag gagccaccta cctgtggata
901 cagctcaacg ccaactccat caatggggat gggcccattg tggcccgaga ggtggagtac
961 tgcacggcca gtgggagctg gaatgaccgg cagccagtcg attccacgag ctataaaatt
1021 ggacaccttg acccagatac agaatatgag attagtgtgc tcctgaccag gccaggggag
1081 ggtggcactg gctctcctgg tccagctctc aggacaagaa caaagtgtgc tgatcccatg
1141 cgaggcccaa gaaaactaga agtagtggag gtcaaatctc ggcaaatcac tatccgctgg
1201 gagccatttg gatataatgt aactcgttgc cacagttata atctcactgt ccactactgt
1261 taccaagttg gaggacaaga acaagtgcga gaagaagtaa gctgggatac agaaaattca
1321 caccctcaac acacgatcac taacctgtca ccatacacca atgtcagtgt gaaactgatc
1381 ctcatgaacc cagagggccg gaaggaaagc caagaactca tagtgcagac agatgaagac
1441 ctcccaggtg ctgttcccac tgaatccata caaggaagta cctttgaaga gaagatattt
1501 cttcagtgga gagaaccaac tcaaacatat ggtgtaatca ctttatatga gatcacctac
1561 aaagcagtca gttcctttga cccagaaata gatttatcca atcagagtgg aagagtttca
1621 aagctgggaa atgaaaccca ttttctgttt tttggactgt atccggggac cacatactcc
1681 tttaccatcc gagctagcac agctaagggt tttgggcctc cagcaacaaa ccagttcacc
1741 accaaaatat cagcaccctc tatgccagct tatgaacttg agacaccttt gaatcaaact
1801 gacaataccg tgacagtcat gctgaaacct gcccacagca gaggagcacc tgtcagtgtc
1861 tatcaaatag ttgttgagga agaacgtcct cgaagaacta aaaagacgac agaaatctta
1921 aagtgctacc cagtgccaat tcacttccag aatgcttctc tgctgaactc acagtactac
1981 tttgctgcag aatttcctgc agacagcctc caagctgcgc agccttttac aattggtgat
2041 aataagacat ataatggata ctggaacact ccccttctcc cctataaaag ctacagaatt
2101 tatttccaag ctgctagtag agccaatggg gaaaccaaaa tagactgtgt ccaagtggcc
2161 acaaaaggag ctgccactcc gaaaccagtc ccagaacccg agaaacagac agaccataca
2221 gttaaaattg ctggagtcat cgcgggcatc ttgctgttcg tgattatatt tcttggagtt
2281 gtgttggtaa tgaagaaaag gaaactggcc aagaagcgga aagagaccat gagcagcacc
2341 cgacaggaga tgactgtgat ggtgaactca atggacaaga gctatgctga gcagggcaca
2401 aactgcgacg aggctttctc attcatggac acgcacaatc tgaatgggag atctgtgtct
2461 tcaccatcgt ccttcacaat gaaaacaaat acactgagca catcggtgcc taattcctat
2521 tacccagatg aaacccacac aatggccagc gataccagca gcctggtgca gtcccatact
2581 tacaagaagc gagagccggc cgacgtgccc tatcagactg ggcagctcca ccccgccatc
2641 cgggtggcag acctccttca gcacatcaca cagatgaagt gtgcggaggg ctacggcttc
2701 aaggaggaat acgagagctt ctttgaaggg cagtctgcac catgggactc ggctaagaaa
2761 gatgagaaca gaatgaagaa cagatacggg aatatcattg catacgatca ttcccgagtg
2821 aggctgcaga caatagaagg agacacaaac tcagactata tcaatggcaa ttatatcgat
2881 ggttatcatc gacccaatca ttacattgct acccaagggc caatgcagga aaccatctat
2941 gacttctgga ggatggtgtg gcacgaaaac actgcaagta tcatcatggt gaccaatctt
3001 gtggaagtgg gaagggtcaa atgctgcaaa tactggccag atgacacaga gatatataaa
3061 gacattaaag ttaccctaat agaaacagaa ctactggcag aatatgtgat aagaacattt
3121 gctgttgaaa agagaggtgt gcatgaaatc cgagagatca gacagtttca cttcactggc
3181 tggccggatc atggggtccc ctaccatgcc accggcctgc tgggattcgt gcggcaagtc
3241 aagtccaaga gcccgcccag tgcaggccca ctggtggtgc actgcagtgc tggtgcaggg
3301 aggactggct gtttcatcgt cattgatatc atgttggaca tggccgaaag ggaaggggtc
3361 gtagacatct acaactgcgt cagggagctg cggtcacgga gggtgaacat ggtgcaaaca
3421 gaggagcagt atgtgtttat ccacgatgcg atcctggaag cctgtctttg tggggacacc
3481 tctgtgcctg cttcccaagt taggtctctg tattatgaca tgaacaaact ggatccacag
3541 acaaactcaa gccagattaa agaggaattc cggacgctaa acatggtgac accaacgctg
3601 cgagtagagg actgcagcat cgcactgttg ccccggaacc atgagaaaaa ccggtgcatg
3661 gacatcctgc ccccagaccg ctgcctgccc ttcctcatca ccatcgatgg ggagagcagc
3721 aactacatca atgctgccct catggacagc tataaacagc cttcagcttt tatagtcacc
3781 cagcatcctt tgccaaacac agtgaaagac ttttggagac tggtcctgga ttatcactgc
3841 acatccgtag ttatgctaaa tgatgtggat cctgcccagt tgtgtccaca gtactggcca
3901 gaaaacggag tacacagaca cggccccatc caggtggaat ttgtctctgc tgacctggaa
3961 gaggacatca tcagcaggat attccgcatt tacaatgccg ccagacccca agatggatat
4021 cggatggtgc agcaattcca gttcctgggc tggccgatgt acagggacac accagtgtct
4081 aagcgctcct tcttgaagct cattcgccag gtggacaagt ggcaagagga atacaatggc
4141 ggggaaggcc cgaccgttgt gcactgcttg aacgggggag gccgcagtgg gacgttctgc
4201 gccatcagca tcgtatgtga gatgctccgg caccagagaa ccgtggatgt ctttcacgct
4261 gtgaagacac tgaggaacaa caagcccaac atggtcgacc tcctggatca gtacaagttc
4321 tgctacgagg tggccctgga atacttgaat tctggctgat ggtgtaaaca gctctgcaaa
4381 caatcccttt cataccacaa agccaagacg ttccatggta tttgtgcaaa agagatgaag
4441 acttctcaat atgcttattt tgctttgact aattggctct ttttaagagc caagaaagtg
4501 tttctaaaat tgcttgcact gcccaatccc agtaatgctg ctgcctgaca gaaacacaca
4561 cacagccaca gttgccaaat ncccgtactc cttgccacgg ttctagagca gcgtagacag
4621 ctggtaaact gaagagcaca actatattct tatgaaggaa tttgtacctt tggggtatta
4681 ttttgtggcc cgtgaccctc gttattgtta cagctgagtg tatgtttttg ttctgtggag
4741 aatgctatct ggcattatgg taatatatta ttttaggtaa tatttgtact ttaacatgtt
4801 gcataatata tgcttatgta gctttccagg actaacagat aaatgtgtaa taacaaagat
4861 atgttgtatg agtngtcgtt tctgtcagat ttgtattgtt tccaagggaa aannttgggg
4921 gaggactcag ttcacaaaat gcaaaactca acgatcagat tcacggaccc agagcttttc
4981 catgtgttta tattgtaa
//