LOCUS X57206 4505 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for 1D-myo-inositol-trisphosphate 3-kinase B
isoenzyme.
ACCESSION X57206
VERSION X57206.1
KEYWORDS inositol 1,4,5-triphosphate 3-kinase; isoenzyme.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4505)
AUTHORS Takazawa K.
JOURNAL Submitted (11-JAN-1991) to the INSDC. K. Takazawa, I R I B H N
SCHOOL OF MEDICINE, FREE UNIVERSITY OF BRUSSELS (ULB), CAMPUS
ERASME (BAT C), ROUTE DE LENNICK 808, B-1070 BRUSSELS, BELGIUM
REFERENCE 2
AUTHORS Takazawa K., Erneux C.
TITLE Molecular cloning and expression of a new putative inositol
1,4,5-trisphosphate 3-kinase isoenzyme
JOURNAL Biochem. J. 278(0), 883-886(1991).
PUBMED 1654894
FEATURES Location/Qualifiers
source 1..4505
/db_xref="H-InvDB:HIT000322075"
/organism="Homo sapiens"
/mol_type="mRNA"
/sex="female"
/dev_stage="2 years old"
/clone_lib="cDNA"
/clone="hh2T"
/tissue_type="hippocampus"
/db_xref="taxon:9606"
CDS 102..1520
/product="1D-myo-inositol-trisphosphate 3-kinase"
/EC_number="2.7.1.127"
/db_xref="GOA:P27987"
/db_xref="H-InvDB:HIT000322075.15"
/db_xref="HGNC:HGNC:6179"
/db_xref="InterPro:IPR005522"
/db_xref="InterPro:IPR038286"
/db_xref="UniProtKB/Swiss-Prot:P27987"
/protein_id="CAA40491.1"
/translation="MLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGL
AWTRGTGVQSEGTWESQRQDSDALPSPELLPQDQDKPFLRKACSPSNIPAVIITDMGT
QEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFL
HTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKH
CESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRT
YLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTAT
LGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLE
VSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDG
YLSGLNNLVDILTEMSQDAPLA"
BASE COUNT 1001 a 1213 c 1266 g 1025 t
ORIGIN
1 gaattccgga gggagggtcc ccaacgctgg gcttgcttgg gggcagcccc tcagcacagc
61 cggggaccgg gaatgtggag gcgggaattc cttctggcag aatgctggag cctttgccct
121 gttgggacgc tgcgaaagat ctgaaagaac ctcagtgccc tcctggggac agggtgggtg
181 tgcagcctgg gaactccagg gtttggcagg gcaccatgga gaaagccggt ttggcttgga
241 cgcgtggcac aggggtgcaa tcagagggga cttgggaaag ccagcggcag gacagtgatg
301 ccctcccaag tccggagctg ctaccccaag atcaggacaa gcctttcctg aggaaggcct
361 gcagccccag caacatacct gctgtcatca ttacagacat gggcacccag gaggatgggg
421 ccttggagga gacgcaggga agccctcggg gcaacctgcc cctgaggaaa ctgtcctctt
481 cctcggcctc ctccacgggc ttctcctcat cctacgaaga ctcagaggag gacatctcca
541 gtgaccctga gcgcaccctg gaccccaact cagctttcct gcataccctg gaccagcaga
601 aacctagagt gagcaaatca tggaggaaga taaaaaacat ggtgcactgg tctcccttcg
661 tcatgtcctt caagaagaag tacccctgga tccagctggc aggacacgca gggagtttca
721 aggcagctgc caatggcagg atcctgaaga agcactgtga gtcagagcag cgctgcctgg
781 accggctgat ggtggatgtg ctgaggccct tcgtacctgc ctaccatggg gatgtggtga
841 aggacgggga gcgctacaac cagatggacg acctgctggc cgacttcgac tcgccctgtg
901 tgatggactg caagatggga atcaggacct acctggagga ggagctcacg aaggcccgga
961 agaagcccag cctgcggaag gacatgtacc agaagatgat cgaggtggac cccgaggccc
1021 ccaccgagga ggaaaaagca cagcgggctg tgaccaagcc acggtacatg cagtggcggg
1081 agaccatcag ctccacggcc accctggggt tcaggatcga gggaatcaag aaagaagacg
1141 gcaccgtgaa ccgggacttc aagaagacca aaacgaggga gcaggtcacc gaggccttca
1201 gagagttcac taaaggaaac cataacatcc tgatcgccta tcgggaccgg ctgaaggcca
1261 ttcgaaccac tctagaagtt tctcccttct tcaagtgcca cgaggtcatt ggcagctccc
1321 tcctcttcat ccacgacaag aaggaacagg ccaaagtgtg gatgatcgac tttgggaaaa
1381 ccacgcccct gcctgagggc cagaccctgc agcatgacgt cccctggcag gaggggaacc
1441 gggaggatgg ctacctctcg gggctcaata acctcgtcga catcctgacc gagatgtccc
1501 aggatgcccc actcgcctga gctgcccacg ccctccctgg cccccgcctg ggcctccttt
1561 cctcctcctg tgcttccttt ctcgttccta acttttcctt cacttacacc tgactgaccc
1621 tcctgaactg cactacaaga cactttgtag aagaggagat gagagtttct agtcattttc
1681 ctaacttcag ggcttggagg tggtgtttgc actgcttttt gtagagaggg tcacctacta
1741 gaagagaaat gcccagtctt agaggtgggt caggtgtaga gctggagggg gtccctggct
1801 gctgagggga ccctaccaga tgagccctgc ctctgggagc cccctaggaa gcaccagcct
1861 ggacctacca cctgcggagg cctgctgccc cctggcggcc agtgctgtta gagtgctgcc
1921 aagcacagcc ttatttctgc cggggcctcc ccaccggaga gcccaggggg ccggccgggt
1981 tcctggtccc tggctgggag cagggctttc tggtagttgg ggcacaaaac catcggggaa
2041 ccacatgttg actgtgagca aagtgtcttc cgattagcag cctcagggat gccctggtgg
2101 cctctccagg gctgctcagg caaggccccc cacccatctg gtatggaaac ctgccggctc
2161 caggccagac ccaggagcca agagaaggct gaagccagct tggctgtgtt ctctgatcta
2221 ggccttccca gaggaggcga gcagaagctg tgccacttgg aattgcaacc catgagttca
2281 gaaggcacac tctgccatgc tgagctccaa gggtgctacc aggggaagat gggatctata
2341 gagtctctgg gccctggccc cagggaggag cacatttttc ttgaccctca cctacctggt
2401 gctagttggt caaccctgcc tgcatacatg ggctcctgtc atggggccca gagtcccttg
2461 cagatataga aataggggag gagctcaggt ctgcgccagg caggaagaag gcaggcttct
2521 ggcttccaga ggtgccgcgg tggcctcctg gcatcatttg ttattgcctc tgaaacaagc
2581 cttactgcct ggagggctta gattcctgct tccccaatgt agtgtgggta tcttgtaggg
2641 tatgtggtgg atgccagggc gtgctccagg cacctcttcc tgaagtctct gcatttggag
2701 attcgtggag aacctattta agcccaattt taactgaaag ccagtgagtc tgatatggaa
2761 gggaatgtaa aatttgcctg acttcttaag aacaaaaccc ccagctctgt gccccatgct
2821 ccttggggct tgccacccac tcctttgctg tcagaggtac aggagctggg agagtccagg
2881 agctagggac acagagggag actatggacc aaggtgtgtg tgtctggagg aaccactgcc
2941 caccccacca ccccggggtc tctggggaac tgtcaacctg cccacgggac atgtacattt
3001 ccccttttgt gctggaagtg tgagtgacac ttgctggggg tggagggtgg gacacatgag
3061 gatgtataag tacagatttt aaaaaaggaa atcaacttac acttcctggc tcttgtttaa
3121 aacagtggtg agctcctgtg tgggccgact tgctaaaggt cacacacgcg cccggtggag
3181 cacgagagac ctcgtggcag catgtgatct ggaaggcagg caggacgggg gcgttgggga
3241 gccaaagtca actctgggcc tctggagcta tagtgacttt tgggctagaa gggaccctgg
3301 tggtctgtgc ttcagccatt tgcagggcag gggcatcatt aattcagacg taaagattct
3361 atgaatatgg actggccaaa agttatcctt actccatctg tgaaagaagt ttgctaaagc
3421 aaatcatgat atgaacaaaa attacagggg acctgtttaa gagaacaaaa tgttccaagc
3481 actttaggca gacaccagct gtttgcaaac aatgtgctaa tatgcaaatg atgtgcttat
3541 taaaggaggc ccatggggcc tcttattggc aatacttggc tgtgggttac attaaatatg
3601 tgaacatagt atgaagtagc atcattttag ggttattctg ttacttaggg tttttgtttt
3661 ctgttttttt tttctctttt tttgtattta ccgtgctagt tctcttctac acctactctg
3721 tctctcaagc cattttgcca ctcgcttccc tgccatctgg cccttccctt tgtctcagtg
3781 ggatagatgg attgtgaaat ggaatctccc agaacccctg ccctggcagc ctggaagacc
3841 gtgcctgccc agccctcgtc accacaggga ctccttgggt cctggcagtg catgtgccag
3901 caggcaggac aaactctgtg tacctgtgcc caggtgaatg ggcgcagggt cctcttgccc
3961 tgtcctgcgg ggggccccac gagttcctgg cattcagcac tgcttagcat tctcggaagg
4021 tttcttcaac tgcttgcttt tcccaggctt gcctttagtg tcatgtaaga catttttaag
4081 ttatatttat tttgttgggt tttaaaattg cacagaacac taagaccgaa aggctggact
4141 cttgtttctc cttgaaagct ttgcctttgt tttgaacttc ctttcccact tggtagaaag
4201 agcccagaag cagccctggc cctgtaagat ggactctttc atccttcagt tgtatttagc
4261 tttgagtttc tctgcatctg tccaccccat gtgtatataa cccagcccct ggctctgggg
4321 tggtcacctc gtcagtgcct tttgttctgg aggagaggac ccccccgcct gccgagaggc
4381 tctcttcctg ttctgcaccc ctctccccat gggaccttgg agaaaactga actgttacaa
4441 acccctgcac agtgcctgtc aaacagatgc aaaccttcct gaataaagcc ttggagacgg
4501 aattc
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