LOCUS X55762 1185 bp mRNA linear HUM 09-SEP-2004
DEFINITION Human mRNA for glycosylasparaginase.
ACCESSION X55762 S57449
VERSION X55762.1
KEYWORDS glyosylasparaginase; signal peptide.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1185)
AUTHORS Fisher K.
JOURNAL Submitted (14-OCT-1990) to the INSDC.
REFERENCE 2 (bases 1 to 1185)
AUTHORS Fisher K.J., Tollersrud O.K., Aronson N.N.
TITLE Cloning and sequence analysis of a cDNA for human
glycosylasparaginase.
JOURNAL FEBS Lett. 269(2), 440-444(1990).
PUBMED 2401370
REFERENCE 3
AUTHORS Park H., Vettese M.B., Fensom A.H., Fisher K.J., Aronson N.N.Jr.
TITLE Characterization of three alleles causing aspartylglycosaminuria:
two from a British family and one from an American patient.
JOURNAL Biochem. J. 290, 735-741(1993).
PUBMED 8457202
COMMENT Data kindly reviewed (29-APR-1991) by Fisher K.J.
FEATURES Location/Qualifiers
source 1..1185
/db_xref="H-InvDB:HIT000321991"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 28..1068
/note="glycosylasparaginase precursor (AA -23 to 323)"
/db_xref="GOA:P20933"
/db_xref="H-InvDB:HIT000321991.12"
/db_xref="HGNC:HGNC:318"
/db_xref="InterPro:IPR000246"
/db_xref="InterPro:IPR029055"
/db_xref="PDB:1APY"
/db_xref="PDB:1APZ"
/db_xref="UniProtKB/Swiss-Prot:P20933"
/protein_id="CAA39288.1"
/translation="MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAW
RALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAV
GDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTSASQALHSDWLA
RNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHI
AAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYM
RRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSE
KNQPTEEKVDCI"
sig_peptide 28..96
/note="signal peptide (AA -23 to -1)"
mat_peptide 97..1065
/note="mature glycosylasparaginase (AA 1-323)"
misc_feature 1179..1184
/note="polyA signal"
BASE COUNT 338 a 256 c 284 g 307 t
ORIGIN
1 tcgcgctggt ctcttcggtg gtcagggatg gcgcggaagt cgaacttgcc tgtgcttctc
61 gtgccgtttc tgctctgcca ggccctagtg cgctgctcca gccctctgcc cctggtcgtc
121 aacacttggc cctttaagaa tgcaaccgaa gcagcgtgga gggcattagc atctggaggc
181 tctgccctgg atgcagtgga gagcggctgt gccatgtgtg agagagagca gtgtgacggc
241 tctgtaggct ttggaggaag tcctgatgaa cttggagaaa ccacactaga tgccatgatc
301 atggatggca ctactatgga tgtaggagca gtaggagatc tcagacgaat taaaaatgct
361 attggtgtgg cacggaaagt actggaacat acaacacaca cacttttagt aggagagtca
421 gccaccacat ttgctcaaag tatggggttt atcaatgaag acttatctac cagtgcttct
481 caagctcttc attcagattg gcttgctcgg aattgccagc caaattattg gaggaatgtt
541 ataccagatc cctcaaaata ctgcggaccc tacaaaccac ctggtatctt aaagcaggat
601 attcctatcc ataaagaaac agaagatgat cgtggtcatg acactattgg catggttgta
661 atccataaga caggacatat tgctgctggt acatctacaa atggtataaa attcaaaata
721 catggccgtg taggagactc accaatacct ggagctggag cctatgctga cgatactgca
781 ggggcagccg cagccactgg gaatggtgat atattgatgc gcttcctgcc aagctaccaa
841 gctgtagaat acatgagaag aggagaagat ccaaccatag cttgccaaaa agtgatttca
901 agaatccaga agcattttcc agaattcttt ggggctgtta tatgtgccaa tgtgactgga
961 agttacggtg ctgcttgcaa taaactttca acatttactc agtttagttt catggtttat
1021 aattccgaaa aaaatcagcc aactgaggaa aaagtggact gcatctaatc catctttact
1081 gtcaacatct gtatttaaag aagaaagaaa caaaggctga aaaggctgct cactctcatc
1141 atctagtgtt cctcatgtgt tctaaagtct ttttgtaaaa taaac
//