LOCUS X55733 3878 bp DNA linear HUM 18-APR-2005
DEFINITION H.sapiens initiation factor 4B cDNA.
ACCESSION X55733
VERSION X55733.1
KEYWORDS initiation factor 4B.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3878)
AUTHORS Milburn S.C., Hershey J.W.B., Davies M.V., Kelleher K.,
Kaufman R.J.
TITLE Cloning and expression of eukaryotic initiation factor 4B cDNA:
sequence determination identifies a common RNA recognition motif
JOURNAL EMBO J. 9(9), 2783-2790(1990).
PUBMED 2390971
FEATURES Location/Qualifiers
source 1..3878
/organism="Homo sapiens"
/mol_type="genomic DNA"
/clone_lib="Stratagene"
/tissue_type="osteosarcoma"
/db_xref="taxon:9606"
CDS 20..1855
/product="initation factor 4B"
/db_xref="GOA:P23588"
/db_xref="HGNC:HGNC:3285"
/db_xref="InterPro:IPR000504"
/db_xref="InterPro:IPR012677"
/db_xref="InterPro:IPR033107"
/db_xref="InterPro:IPR035979"
/db_xref="PDB:1WI8"
/db_xref="PDB:2J76"
/db_xref="PDB:6FEC"
/db_xref="UniProtKB/Swiss-Prot:P23588"
/protein_id="CAA39265.1"
/translation="MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADET
DDLEGDVSTTWHSNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGN
LPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEES
LGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDD
SFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGS
GRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKL
NLKPRSTPEEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQWN
EPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENET
LNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSG
GGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKK
DQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGEDYAE"
regulatory 1942..1947
/regulatory_class="polyA_signal_sequence"
regulatory 2300..2305
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1123 a 786 c 942 g 1026 t
ORIGIN
1 tctagagccc tctcccaaca tggcggcctc agcaaaaaag aagaataaga aggggaagac
61 tatctcccta acagactttc tggctgagga tgggggtact ggtggaggaa gcacctatgt
121 ttccaaacca gtcagctggg ctgatgaaac ggatgacctg gaaggagatg tttcgaccac
181 ttggcacagt aacgatgacg atgtgtatag ggcgcctcca attgaccgtt ccatccttcc
241 cactgctcca cgggctgctc gggaacccaa tatcgaccgg agccgtcttc ccaaatcgcc
301 accctacact gcttttctag gaaacctacc ctatgatgtt acagaagagt caattaagga
361 attctttcga ggattaaata tcagtgcagt gcgtttacca cgtgaaccca gcaatccaga
421 gaggttgaaa ggttttggtt atgctgaatt tgaggacctg gattccctgc tcagtgccct
481 gagtctcaat gaagagtctc taggtaacag gagaattcga gtggacgttg ctgatcaagc
541 acaggataaa gacagggatg atcgttcttt tggccgtgat agaaatcggg attctgacaa
601 aacagataca gactggaggg ctcgtcctgc tacagacagc tttgatgact acccacctag
661 aagaggtgat gatagctttg gagacaagta tcgagatcgt tatgattcag accggtatcg
721 ggatgggtat cgggatgggt atcgggatgg cccacgccgg gatatggatc gatatggtgg
781 ccgggatcgc tatgatgacc gaggcagcag agactatgat agaggctatg attcccggat
841 aggcagtggc agaagagcat ttggcagtgg gtatcgcagg gatgatgact acagaggagg
901 cggggaccgc tatgaagacc gatatgacag acgggatgat cggtcgtgga gctccagaga
961 tgattactct cgggatgatt ataggcgtga tgatagaggt cccccccaaa gacccaaact
1021 gaatctaaag cctcggagta ctcctgaaga agatgattcc tctgctagta cctcccagtc
1081 cactcgagct gcttctatct ttggaggggc aaagcctgtt gacacagctg ctagagaaag
1141 agaagtagaa gaacggctac agaaggaaca agagaagttg cagcgtcagt ggaatgagcc
1201 aaaactagaa cgacggcctc gggagagaca cccaagctgg cgaagtgaag aaactcagga
1261 acgggaacgg tcgaggacag gaagtgagtc atcacaaact gggacctcca ccacatctag
1321 cagaaatgca cgaaggagag agagtgagaa gtctctagaa aatgaaacac tcaataagga
1381 ggaagattgc cactctccaa cttctaaacc tcccaaacct gatcagcccc taaaggtaat
1441 gccagcccct ccaccaaagg agaatgcttg ggtgaagcga agttctaacc ctcctgctcg
1501 atctcagagc tcagacacag agcagcagtc ccctacaagt ggtgggggaa aagtagctcc
1561 agctcaacca tctgaggaag gaccaggaag gaaagatgaa aataaagtag atgggatgaa
1621 tgccccaaaa ggccaaactg ggaactctag ccgtggtcca ggagacggag ggaacagaga
1681 ccactggaag gagtcagata ggaaagatgg caaaaaggat caagactcca gatctgcacc
1741 tgagccaaag aaacctgagg aaaatccagc ttctaagttc agttctgcaa gcaagtatgc
1801 tgctctctct gttgatggtg aagatgaaaa tgagggagaa gattatgccg aatagacctc
1861 tacatcctgt gcttttctcc tagtttctct ccaccctgga acattcgaga gcaaatcaaa
1921 acctctatcc agacaagaca aaataaaact caacatctcc tgaagacctt tcttaccttt
1981 ttttaaaaac aaaaantgaa attattttgc atgctgctgc agcctttaaa gtattgaagt
2041 aactggagaa ttgccaatac agccagagag aaagggacta cagcttttta gaggaaaagt
2101 tgtggtgcgt tatgtcacca tgcagttgcc agtgtgatta gtgcctaggg gtctcattta
2161 gcagaaatgg taatgacagt gatataatgc ctggaacctg gttgggcagt aggggaggga
2221 ggtagaagga aaagtgtgag atttctacct tttagttttc atcctattgt ggcatatatg
2281 aattctcaaa cattatctga ataaattttc cactcttgga aaggtagatt tagcctcaag
2341 ttgttctagt ctccaggagg ctgccagccc ctcctcttat ttaattctga gttttggggg
2401 ccagcctaga gggaattcct tttttttttt ttttaacccc ccaggggggt agttgggagt
2461 gagactatag gccataaaga atgggactgc attggaccaa aataaatggg aaaatcgtgg
2521 tttgaaaaga agcttttggg aagtgatgag tcattttgca ccaggtaata ggggaaaatt
2581 gtgtgacctc cagcaaacac atgaatggtt atttcctgga gccggaagca cttgggggtc
2641 gtggtaattc ccagtgtttt ctgtgtccta gttttaccct ttctaaacac tgtccttttt
2701 gaaagttttg aatatatcca cattctattg aaaccttgaa actaaaaatt tagactctta
2761 tcgtcatctt aagttcttca tgctactctt aacctcccaa aaagcagtat ctaagtcaca
2821 tacatgatgt cttgggcatt ttctgagcca tggagaactc tgaaaggaag aatcgctgct
2881 tttctcaagc aaatcggttt cttgatgtct tttggttctc cttgcctgct cctgatgctt
2941 ggaccccttt tattgatcag agtgctctag aataatggat ggtcttggat gatggataaa
3001 tagggacagg gacagttaaa ttgggagcct ttcttacaac cttgatggga tttttccccc
3061 caagtttcct tctccactga aatgccacac taatgcttgt tggattcatg aggtggccag
3121 accaatgtgt tgttttgttg ttgttttttt tttaagcttc ccttgagaga ataaatggta
3181 atggagagaa tcatttaaca aggtcctggt ttctcttgca acacagtagc taaacttgcc
3241 tgcttttata tgcatttttg tagggatcag cttggtagac agtattagcg gagaaacacc
3301 ttgatcttgg tttgcaagcc cttctcccat cagtcctaga ttaggccctg ttcagccatg
3361 caggggtgtt ggtttatgcg tgctgcagca gtgggcataa tgaatataat ttacccagtg
3421 gacaaaggtg tgtaccaagt gaatttaaat aattggtgtg gattggccag tagctaagaa
3481 gtgggctttt aaagagtatt gaagattgaa agggtttttc tttctttttt aaaaaagaaa
3541 aacaaactat tgattgtaga taatgaaaag ctagggtttg ccctcttcat gtctactctc
3601 cttccaaata gttatatcca aaactgtttt tccctctccc ctaccttgtc ccccctatta
3661 aaatagaaac agggattgat taatgtcccg ctcctgaata catgtaaaat ttgtacaaaa
3721 atatcttcta tgaaaatgat ttgtaatctg tagacttatt acctgggaga tgtcttgatg
3781 taaaatccca tcctttgggt tgtgggtttt ttgttttctc caaataaatc tgatctttaa
3841 agttaaaaaa aaaaaaaaac tctagagtcg aggaattc
//