LOCUS X55037 1475 bp mRNA linear HUM 21-OCT-2008
DEFINITION H.sapiens GATA-3 mRNA.
ACCESSION X55037
VERSION X55037.1
KEYWORDS enhancer binding-protein; hGATA-3 gene; transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1475)
AUTHORS Leiden J.M.
JOURNAL Submitted (29-JAN-1991) to the INSDC. J.M. Leiden, Howard Hughes
Medical Institute, University of Michigan, 1150 W Medical Centre
Drive, MSRB I Room 4510, Ann Arbor MI 48109, U S A
REFERENCE 2 (bases 1 to 1475)
AUTHORS Ho I.C., Vorhees P., Marin N., Oakley B.K., Tsai S.F., Orkin S.H.,
Leiden J.M.
TITLE Human GATA-3: a lineage-restricted transcription factor that
regulates the expression of the T cell receptor alpha gene
JOURNAL EMBO J. 10(5), 1187-1192(1991).
PUBMED 1827068
FEATURES Location/Qualifiers
source 1..1475
/db_xref="H-InvDB:HIT000321956"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda-gt11"
/clone="hGATA-3"
/cell_line="Jurkat"
/cell_type="T lymphocyte"
/db_xref="taxon:9606"
mRNA 1..1475
/gene="hGATA-3"
CDS 125..1456
/gene="GATA-3"
/db_xref="GOA:P23771"
/db_xref="H-InvDB:HIT000321956.13"
/db_xref="HGNC:HGNC:4172"
/db_xref="InterPro:IPR000679"
/db_xref="InterPro:IPR013088"
/db_xref="InterPro:IPR016374"
/db_xref="InterPro:IPR029521"
/db_xref="InterPro:IPR039355"
/db_xref="PDB:4HC7"
/db_xref="PDB:4HC9"
/db_xref="PDB:4HCA"
/db_xref="UniProtKB/Swiss-Prot:P23771"
/protein_id="CAA38877.1"
/translation="MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLP
EEVDVLFNIDGQGNHVPPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKV
LGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKD
VSPDPSLSTPGSGGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHP
ITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRR
DGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANG
DPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFN
PAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG"
misc_feature 911..1148
/note="zinc finger region"
BASE COUNT 303 a 578 c 380 g 214 t
ORIGIN
1 aaagcaaatc attcaacgac ccccgaccct ccgacggcag gagccccccg acctcccagg
61 cggacccgct ccctccccgc gcggcgttcc gggcccggcg agaggcgcga gcacagccga
121 ggccatggag gtgacggcgg accagccgcg ctgggtgagc caccaccacc ccgccgtgct
181 caacgggcag cacccggaca cgcaccaccc gggcctcagc cactcctaca tggacgcggc
241 gcagtacccg ctgccggagg aggtggatgt gctttttaac atcgacggtc aaggcaacca
301 cgtcccgccc tactacggaa actcggtcag ggccacggtg cagaggtacc ctccgaccca
361 ccacgggagc caggtgtgcc gcccgcctct gcttcatgga tccctaccct ggctggacgg
421 cggcaaagtc ctgggcagcc accacaccgc ctccccctgg aatctcagcc ccttctccaa
481 gacgtccatc caccacggct ccccggggcc cctctccgtc taccccccgg cctcgtcctc
541 ctccttgtcg gggggccacg ccagcccgca cctcttcacc ttcccgccca ccccgccgaa
601 ggacgtctcc ccggacccat cgctgtccac cccaggctcc ggcggctcgg cccggcagga
661 cgagaaagag tgcctcaagt accaggtgcc cctgcccgac agcatgaagc tggagtcgtc
721 ccactcccgt ggcagcatga ccgccctggg tggagcctcc tcgtcgaccc accaccccat
781 caccacctac ccgccctacg tgcccgagta cagctccgga ctcttccccc ccagcagcct
841 gctgggcggc tcccccaccg gcttcggatg caagtccagg cccaaggccc ggtccagcac
901 aggcagggag tgtgtgaact gtggggcaac ctcgacccca ctgtggcggc gagatggcac
961 gggacactac ctgtgcaacg cctgcgggct ctatcacaaa atgaacggac agaaccggcc
1021 cctcattaag cccaagcgaa ggctgtctgc agccaggaga gcagggacgt cctgtgcgaa
1081 ctgtcagacc accacaacca cactctggag gaggaatgcc aatggggacc ctgtctgcaa
1141 tgcctgtggg ctctactaca agcttcacaa tattaacaga cccctgacta tgaagaagga
1201 aggcatccag accagaaacc gaaaaatgtc tagcaaatcc aaaaagtgca aaaaagtgca
1261 tgactcactg gaggacttcc ccaagaacag ctcgtttaac ccggccgccc tctccagaca
1321 catgtcctcc ctgagccaca tctcgccctt cagccactcc agccacatgc tgaccacgcc
1381 cacgccgatg cacccgccat ccagcctgtc ctttggacca caccacccct ccagcatggt
1441 caccgccatg ggttagagcc ctgctcgatg ctcac
//