LOCUS X52638 1741 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human mRNA for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
(EC 2.7.1.105, EC 3.1.3.46).
ACCESSION X52638
VERSION X52638.1
KEYWORDS 6-phosphofructo-2-kinase; fructose-2,6-bisphosphatase; kinase;
phosphatase; phosphofructokinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1741)
AUTHORS Lange A.J.
JOURNAL Submitted (20-APR-1990) to the INSDC. Lange A.J., SUNY at
Stonybrook, Dept. of Physiology and Biophysics, Health Science
Center, Basic Science Tower Level 6 Room 140, Stonybrook, New York
11794, USA.
REFERENCE 2 (bases 1 to 1741)
AUTHORS Lange A.J., Pilkis S.J.
TITLE Sequence of human liver 6-phosphofructo-2-kinase/fructose-2,6-
bisphosphatase
JOURNAL Nucleic Acids Res. 18(12), 3652-3652(1990).
PUBMED 2163524
COMMENT See <M19938> for conflicting sequence.
FEATURES Location/Qualifiers
source 1..1741
/db_xref="H-InvDB:HIT000321787"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="HL2K-1"
/tissue_type="liver"
/db_xref="taxon:9606"
CDS 80..1495
/note="6-phosphofructo-2-kinase/fructose-2,6-
bisphosphatase (AA 1-471)"
/db_xref="GOA:P16118"
/db_xref="H-InvDB:HIT000321787.12"
/db_xref="HGNC:HGNC:8872"
/db_xref="InterPro:IPR001345"
/db_xref="InterPro:IPR003094"
/db_xref="InterPro:IPR013078"
/db_xref="InterPro:IPR013079"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR029033"
/db_xref="PDB:1K6M"
/db_xref="UniProtKB/Swiss-Prot:P16118"
/protein_id="CAA36861.1"
/translation="MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTM
VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEAL
QIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESI
CNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYI
KIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGL
SVRGKQYAYALANFIQSQGISSLKVWTSRMKRTIQTAEALGVPYEQWKALNEIDAGVC
EEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVIC
HQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREK
PENVDITREPEEALDTVPAHY"
misc_feature 474..476
/note="cca is caa in <M19938>"
misc_feature 879..881
/note="gag is ggg in <M19938>"
misc_feature 882..884
/note="gcc is gac in <M19938>"
misc_feature 992..994
/note="cgc is cac in <M19938>"
misc_feature 1266..1267
/note="gt is gtt in <M19938>"
misc_feature 1272..1274
/note="cgg is cg in <M19938>"
misc_feature 1479..1481
/note="tcc is tac in <M19938>"
misc_feature 1526..1527
/note="cc is ctc in <M19938>"
polyA_site 1741..1741
/note="polyA signal"
BASE COUNT 468 a 457 c 426 g 390 t
ORIGIN
1 gaattccgga caggtagtaa gataggaagt gaggccaggt accttgtggg cagtgatgtc
61 attcggtgcg actcctaaga tgtctccaga gatgggagag ctcacccaaa ccaggttgca
121 gaagatctgg attccacaca gcagcggcag cagcaggctg caacggagaa ggggctcatc
181 cataccccag tttaccaatt cccccacaat ggtgatcatg gtgggtttac cagctcgagg
241 caagacctat atctccacaa agctcacacg atatctcaac tggataggaa caccaactaa
301 agtgtttaat ttaggccagt atcgacgaga ggcagtgagc tacaagaact atgaattctt
361 tcttccagac aacatggaag ccctgcaaat caggaagcag tgcgccctgg cagccctgaa
421 ggatgttcac aactatctca gccatgagga aggtcatgtt gcggtttttg atgccaccaa
481 cactaccaga gaacgacggt cactgatcct gcagtttgca aaagaacatg gttacaaggt
541 gtttttcatt gagtccattt gtaatgaccc tggcataatt gcagaaaaca tcaggcaagt
601 gaaacttggc agccctgatt atatagactg tgaccgggaa aaggttctgg aagactttct
661 aaagagaatt gagtgctatg aggtcaacta ccaacccttg gatgaggaac tggacagcca
721 cctgtcctac atcaagatct tcgacgtggg cacacgctac atggtgaacc gagtgcagga
781 tcacatccag agccgcacag tctactacct catgaatatc catgtcacac ctcgctccat
841 ctacctttgc cgacatggcg agagtgaact caacatcaga ggccgcatcg gaggtgactc
901 tggcctctca gttcgcggca agcagtatgc ctatgccctg gccaacttca ttcagtccca
961 gggcatcagc tccctgaagg tgtggaccag tcgcatgaag aggaccatcc agacagctga
1021 ggccctgggt gtcccctatg agcagtggaa ggccctgaat gagattgatg cgggtgtctg
1081 tgaggagatg acctatgaag aaatccagga acattaccct gaagaatttg cactgcgaga
1141 ccaagataaa tatcgctacc gctatcccaa gggagagtcc tatgaggatc tggttcagcg
1201 tctggagcca gtgataatgg agctagaacg acaggagaat gtactggtga tctgccacca
1261 ggctgtcatg cggtgcctcc tggcctattt cctggataaa agttcagatg agcttccata
1321 tctcaagtgc cctctgcaca cagtgctcaa actcactcct gtggcttatg gctgcaaagt
1381 ggaatccatc tacctgaatg tggaggccgt gaacacacac cgggagaagc ctgagaatgt
1441 ggacatcacc cgggaacctg aggaagccct ggatactgtc ccagcccact actgagccct
1501 ttccaagaag tcaaactgcc tgtgtcctca tcgccttcca cctttaggaa atgctatctt
1561 tgctcttctc ctactctgcc ttggcctcac tgaggcaccc cacttccagt gaagaagtcc
1621 tccgcaactc ccaaacaagc ctcgcttgct ggccgcaacc aaggagctat ctagctctgg
1681 aggaaacttt ctttcttaat tcctattctc tgacgaataa agacttactg cctacaagag
1741 g
//