LOCUS X51521 3044 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human mRNA for ezrin.
ACCESSION X51521
VERSION X51521.1
KEYWORDS ezrin; kinase substrate; microvilli protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3044)
AUTHORS Hunter T.
JOURNAL Submitted (25-JAN-1990) to the INSDC. Hunter T., The Salk
Institute, Molecular Biology and Virology Laboratory, 10010 North
Torrey Pines Road, San Diego, CA 92138, USA.
REFERENCE 2 (bases 1 to 3044)
AUTHORS Gould K.L., Bretscher A., Esch F.S., Hunter T.
TITLE cDNA cloning and sequencing of the protein-tyrosine kinase
substrate, ezrin, reveals homology to band 4.1
JOURNAL EMBO J. 8(13), 4133-4142(1989).
PUBMED 2591371
COMMENT See also <J05021>.
FEATURES Location/Qualifiers
source 1..3044
/db_xref="H-InvDB:HIT000321660"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="Okayama-Berg"
/clone="F6"
/cell_line="HeLa"
/db_xref="taxon:9606"
CDS 118..1878
/note="ezrin (AA 1-586)"
/db_xref="GOA:P15311"
/db_xref="H-InvDB:HIT000321660.14"
/db_xref="HGNC:HGNC:12691"
/db_xref="InterPro:IPR000299"
/db_xref="InterPro:IPR000798"
/db_xref="InterPro:IPR008954"
/db_xref="InterPro:IPR011174"
/db_xref="InterPro:IPR011259"
/db_xref="InterPro:IPR011993"
/db_xref="InterPro:IPR014352"
/db_xref="InterPro:IPR018979"
/db_xref="InterPro:IPR018980"
/db_xref="InterPro:IPR019747"
/db_xref="InterPro:IPR019748"
/db_xref="InterPro:IPR019749"
/db_xref="InterPro:IPR029071"
/db_xref="InterPro:IPR035963"
/db_xref="InterPro:IPR041789"
/db_xref="PDB:1NI2"
/db_xref="PDB:4RM8"
/db_xref="PDB:4RM9"
/db_xref="PDB:4RMA"
/db_xref="UniProtKB/Swiss-Prot:P15311"
/protein_id="CAA35893.1"
/translation="MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWY
FGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLF
FLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQ
HKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWL
GVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRI
NKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVE
REKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEAD
RMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAK
EAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGI
RDDRNEEKRITEAEKNERVQRQLVTLSSELSQARDENKRTHNDIIHNENMRQGRDKYK
TLRQIRQGNTKQRIDEFEAL"
old_sequence 1709..1711
/note="tcg was tgc in [1]"
/citation=[1]
BASE COUNT 826 a 687 c 855 g 675 t
ORIGIN
1 aggcagggcg ggcgggcgct ctaagggttc tgctctgact ccaggttggg acagcgtctt
61 cgctgctgct ggatagtcgt gttttcgggg atcgaggata ctcaccagaa accgaaaatg
121 ccgaaaccaa tcaatgtccg agttaccacc atggatgcag agctggagtt tgcaatccag
181 ccaaatacaa ctggaaaaca gctttttgat caggtggtaa agactatcgg cctccgggaa
241 gtgtggtact ttggcctcca ctatgtggat aataaaggat ttcctacctg gctgaagctg
301 gataagaagg tgtctgccca ggaggtcagg aaggagaatc ccctccagtt caagttccgg
361 gccaagttct accctgaaga tgtggctgag gagctcatcc aggacatcac ccagaaactt
421 ttcttcctcc aagtgaagga aggaatcctt agcgatgaga tctactgccc ccctgagact
481 gccgtgctct tggggtccta cgctgtgcag gccaagtttg gggactacaa caaagaagtg
541 cacaagtctg ggtacctcag ctctgagcgg ctgatccctc aaagagtgat ggaccagcac
601 aaacttacca gggaccagtg ggaggaccgg atccaggtgt ggcatgcgga acaccgtggg
661 atgctcaaag ataatgctat gttggaatac ctgaagattg ctcaggacct ggaaatgtat
721 ggaatcaact atttcgagat aaaaaacaag aaaggaacag acctttggct tggagttgat
781 gcccttggac tgaatattta tgagaaagat gataagttaa ccccaaagat tggctttcct
841 tggagtgaaa tcaggaacat ctctttcaat gacaaaaagt ttgtcattaa acccatcgac
901 aagaaggcac ctgactttgt gttttatgcc ccacgtctga gaatcaacaa gcggatcctg
961 cagctctgca tgggcaacca tgagttgtat atgcgccgca ggaagcctga caccatcgag
1021 gtgcagcaga tgaaggccca ggcccgggag gagaagcatc agaagcagct ggagcggcaa
1081 cagctggaaa cagagaagaa aaggagagaa accgtggaga gagagaaaga gcagatgatg
1141 cgcgagaagg aggagttgat gctgcggctg caggactatg aggagaagac aaagaaggca
1201 gagagagagc tctcggagca gattcagagg gccctgcagc tggaggagga gaggaagcgg
1261 gcacaggagg aggccgagcg cctagaggct gaccgtatgg ctgcactgcg ggctaaggag
1321 gagctggaga gacaggcggt ggatcagata aagagccagg agcagctggc tgcggagctt
1381 gcagaataca cagccaagat tgccctcctg gaagaggcgc ggaggcgcaa ggaggatgaa
1441 gttgaagagt ggcagcacag ggccaaagaa gcccaggatg acctggtgaa gaccaaggag
1501 gagctgcacc tggtgatgac agcacccccg cccccaccac cccccgtgta cgagccggtg
1561 agctaccatg tccaggagag cttgcaggat gagggcgcag agcccacggg ctacagcgcg
1621 gagctgtcta gtgagggcat ccgggatgac cgcaatgagg agaagcgcat cactgaggca
1681 gagaagaacg agcgtgtgca gcggcagctc gtgacgctga gcagcgagct gtcccaggcc
1741 cgagatgaga ataagaggac ccacaatgac atcatccaca acgagaacat gaggcaaggc
1801 cgggacaagt acaagacgct gcggcagatc cggcagggca acaccaagca gcgcatcgac
1861 gagttcgagg ccctgtaaca gccaggccag gaccaagggc agaggggtgc tcatagcggg
1921 cgctgccagc cccgccacgc ttgtctttag tgctccaagt ctaggaactc cctcagatcc
1981 cagttccttt agaaagcagt tacccaacag aaacattctg ggctgggaac cagggaggcg
2041 ccctggtttg ttttccccag ttgtaatagt gccaagcagg cctgattctc gcgattattc
2101 tcgaatcacc tcctgtgttg tgctgggagc aggactgatt gaattacgga aaatgcctgt
2161 aaagtctgag taagaaactt catgctggcc tgtgtgatac aagagtcagc atcattaaag
2221 gaaacgtggc aggacttcca tctgtgccat acttgttctg tattcgaaat gagctcaaat
2281 tgattttttt aatttctatg aaggatccat ctttgtatat ttacatgctt agaggggtga
2341 aaattatttt ggaaattgag tctgaagcac tctcgcacac acagtgattc cctcctcccg
2401 tcactccacg cagctggcag agagcacagt gatcaccagc gtgagtggtg gaggaggaca
2461 cttggatatt tttttagttc tttttttttt ggcttaacag ttttagaata cattgtactt
2521 atacacctta ttaatgatca gctatatact atttatatac aagtgataat acagatttgt
2581 aacattagtt ttaaaaaggg aaagttttgt tctgtatatt ttgttacctt ttacagaata
2641 aaagaattac atatgaaaaa ccctctaaac catggcactt gatgtgatgt ggcaggaggg
2701 nagtggtgga gctggacctg cctgctgcag ctgcagtcac gtgtaaacag gattattatt
2761 agtgttttat gcatgtaatg gactatgcac acttttaatt ttgtcagatt cacacatgcc
2821 actatgagct ttcagactcc agctgtgaag agactctgtc tgcttgtgtt tgtttgcagt
2881 ctctctctgc catggccttg gcaggctgct ggaaggcagc ttgtggaggc cgttggttcc
2941 gcccactcat tccttctcgt gcactgcttt ctccttcaca gctaagatgc catgtgcagg
3001 tggattccat gccgcagaca tgaaataaaa gctttgcaaa ggca
//