LOCUS X17406 1923 bp mRNA linear HUM 18-APR-2005
DEFINITION Human mRNA for cartilage specific proteoglycan.
ACCESSION X17406
VERSION X17406.1
KEYWORDS cartilage matrix protein; cartilage proteoglycan; extracellular
matrix protein; link protein; proteoglycan.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1923)
AUTHORS Dudhia J.
JOURNAL Submitted (19-JAN-1990) to the INSDC. Dudhia J., Kennedy Institute
of Rheumatology, 6 Bute Gardens, Hammersmith , London W6 7DW, UK.
REFERENCE 2 (bases 1 to 1923)
AUTHORS Dudhia J., Davidson C.M., Wells T.M., Vynios D.H., Hardingham T.E.,
Bayliss M.T.
TITLE Age-related changes in the content of the C-terminal region of
aggrecan in human articular cartilage.
JOURNAL Biochem. J. 313, 933-940(1996).
PUBMED 8611178
FEATURES Location/Qualifiers
source 1..1923
/db_xref="H-InvDB:HIT000321613"
/organism="Homo sapiens"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="lambda gtll"
/clone="lambda HPGD2.4 and DC4"
/cell_type="chondrocyte"
/db_xref="taxon:9606"
CDS <1..1803
/codon_start=1
/product="cartilage specific proteoglycan (600 AA)"
/db_xref="GOA:P16112"
/db_xref="H-InvDB:HIT000321613.12"
/db_xref="HGNC:HGNC:319"
/db_xref="InterPro:IPR000436"
/db_xref="InterPro:IPR000538"
/db_xref="InterPro:IPR000742"
/db_xref="InterPro:IPR001304"
/db_xref="InterPro:IPR003006"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013032"
/db_xref="InterPro:IPR013106"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR016186"
/db_xref="InterPro:IPR016187"
/db_xref="InterPro:IPR018378"
/db_xref="InterPro:IPR033987"
/db_xref="InterPro:IPR035976"
/db_xref="InterPro:IPR036179"
/db_xref="PDB:4MD4"
/db_xref="UniProtKB/Swiss-Prot:P16112"
/protein_id="CAA35463.1"
/translation="EFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSL
VDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEP
SGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVAGVTEPTISQ
ELGQRPPVTHTPQLFESSGKVSTAGDVSGATPVLPGSGVEVSSVPESSSETSAYPEAG
FGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVS
GESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQT
QRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESESTAADQEVCEE
GWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLN
DRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPF
TCKKGTVACGEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHW
EEPRITCTDPTTYKRRLQKRSSRHPRRSRPSTAH"
BASE COUNT 461 a 556 c 540 g 366 t
ORIGIN
1 gaattcagtg gcctaccaag tggcatagct gaggtcagtg gagaatcctc cagagctgag
61 attgggagca gcctgccctc gggagcatat tatggcagtg gaactccatc tagtttcccc
121 acggtctctc ttgtagacag aactttggtg gaatctgtaa cccaggctcc aacagcccaa
181 gaggcaggag aagggccttc tggcatttta gaactcagtg gtgctcattc tggagcacca
241 gacatgtctg gggagcattc tggatttctg gacctaagtg ggctgcagtc cgggctgata
301 gagcccagcg gagagccacc aggtactcca tattttagtg gggattttgc cagcaccacc
361 aatgtaagtg gagaatcctc tgtagccatg ggcaccagtg gagaggcctc aggacttcca
421 gaagttactt taatcacttc tgagttcgtg gcgggtgtta ctgaaccaac tatttctcag
481 gaactaggcc aaaggccccc tgtgacacac acaccccagc tttttgagtc cagtggaaaa
541 gtctccacag ctggggacgt tagtggagct accccagtgc tccctgggtc tggagtagaa
601 gtatcatcag tcccagaatc tagcagtgag acgtccgcct atcctgaagc tgggttcggg
661 gcatctgccg cccctgaggc cagcagagaa gattctgggt cccctgatct gagtgaaacc
721 acctctgcat tccacgaagc taacctcgag agatcctctg gcctaggagt gagcggcagc
781 actttgacat ttcaagaagg cgaggcgtcc gctgccccag aagtgagtgg agaatccacc
841 accaccagtg atgtggggac agaggcacca ggcttgcctt cagccactcc cacggcttct
901 ggagacagga ctgaaatcag cggagacctg tctggtcaca cctcgcagct gggcgttgtc
961 atcagcacca gcatcccaga gtctgagtgg acccagcaga cccagcgccc tgcagagacg
1021 catctagaaa ttgagtcctc aagcctcctg tactcaggag aagagactca cacagtcgaa
1081 acagccacct ccccaacaga tgcgtccatc ccagcttctc cggaatggaa acgtgaatca
1141 gaatcaactg ctgcagacca ggaggtatgt gaggagggct ggaacaagta ccagggccac
1201 tgttaccgcc acttcccgga ccgcgagacc tgggtggatg ctgagcgccg gtgtcgggag
1261 cagcagtcac acctgagcag catcgtcacc cccgaggagc aggagtttgt caacaacaat
1321 gcccaagact accagtggat cggcctgaac gacaggacca tcgaagggga cttccgctgg
1381 tcagatggac accccatgca atttgagaac tggcgcccca accagcctga caactttttt
1441 gccgctggag aggactgtgt ggtgatgatc tggcacgaga agggcgagtg gaatgatgtt
1501 ccctgcaatt accacctccc cttcacgtgt aaaaagggca cagtggcctg cggagagccc
1561 cctgtggtgg agcatgccag gaccttcggg cagaagaagg accggtatga gatcaattcc
1621 ctggtgcggt accagtgcac agaggggttt gtccagcgcc acatgcccac catccggtgc
1681 cagcccagcg ggcactggga ggagcctcgg atcacctgca cagaccccac cacctacaaa
1741 cgcagactac agaagcggag ctcacggcac cctcggagga gccgccccag cacagcccac
1801 tgagaagagc ttccaggacc acccaggacg ctgagcccag gagcctgcca ggctgacgtg
1861 catcccaccc agacggtgtc ctcttcttgt cgctttttgt catataagga atcccaggaa
1921 ttc
//