LOCUS X16996 1110 bp mRNA linear HUM 22-MAR-1995
DEFINITION Human mRNA for T-cell surface glycoprotein E2.
ACCESSION X16996
VERSION X16996.1
KEYWORDS glycoprotein E2; MIC2 gene; pseudoautosome.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1110)
AUTHORS Gelin C., Aubrit F., Phalipon A., Raynal B., Cole S., Kaczorek M.,
Bernard A.
TITLE The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion
processes, is the MIC2 gene product
JOURNAL EMBO J. 8(11), 3253-3259(1989).
PUBMED 2479542
COMMENT E2 is the product of the MIC2 gene which is the only
pseudoautosomal gene sofar described in man
FEATURES Location/Qualifiers
source 1..1110
/db_xref="H-InvDB:HIT000321593_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="BC1"
/cell_line="thymic"
/db_xref="taxon:9606"
CDS 124..681
/note="pre-pro polypeptide (AA -22 to 163)"
/db_xref="GOA:P14209"
/db_xref="H-InvDB:HIT000321593_03.4"
/db_xref="HGNC:HGNC:7082"
/db_xref="InterPro:IPR022078"
/db_xref="UniProtKB/Swiss-Prot:P14209"
/protein_id="CAA34863.1"
/translation="MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIP
KKPSAGDDFDLGDAVVDGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGG
EGKGGSDGGGSHRKEGEEADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAE
QGEVDMESHRNANAEPAVQRTLLEK"
sig_peptide 124..189
/note="signal peptide (AA -22 to -1)"
mat_peptide 190..678
/note="mature polypeptide (AA 1-163)"
misc_feature 1083..1090
/note="polyA signal"
BASE COUNT 246 a 312 c 313 g 239 t
ORIGIN
1 gggcgggcct cacccgcttc gagtcctcgg gcttccccca cccggcccgt gggggagtat
61 ctgtcctgcc gccttcgccc acgccctgca ctccgggacc gtccctgcgc gctctgggcg
121 accatggccc gcggggctgc gctggcgctg ctgctcttcg gcctgctggg tgttctggtc
181 gccgccccgg atggtggttt cgatttatct gatgcccttc ctgacaatga aaacaagaaa
241 cccactgcaa tccccaagaa acccagtgct ggggatgact ttgacttagg agatgctgtt
301 gttgatggag aaaatgacga cccacgacca ccgaacccac ccaaaccgat gccaaatcca
361 aaccccaacc accctagttc ctccggtagc ttttcagatg ctgaccttgc ggatggcgtt
421 tcaggtggag aaggaaaagg aggcagtgat ggtggaggca gccacaggaa agaaggggaa
481 gaggccgacg ccccaggcgt gatccccggg attgtggggg ctgtcgtggt cgccgtggct
541 ggagccatct ctagcttcat tgcttaccag aaaaagaagc tatgcttcaa agaaaatgca
601 gaacaagggg aggtggacat ggagagccac cggaatgcca acgcagagcc agctgttcag
661 cgtactcttt tagagaaata gaagattgtc ggcagaaaca gcccaggcgt tggcagcagg
721 gttagaacag ctgcctgagg ctcctccctg aaggacacct gcctgagagc agagatggag
781 gccttctgtt cacggcggat tctttgtttt aatcttgcga tgtgctttgc ttgttgctgg
841 gcggatgatg tttactaacg atgaatttta catccaaagg gggataggca cttggacccc
901 cattctccaa ggcccggggg ggcggtttcc catgggatgt gaaaggctgg ccattattaa
961 gtccctgtaa ctcaaatgtc aaccccaccg aggcaccccc ccgtccccca gaatcttggc
1021 tgtttacaaa tcacgtgtcc atcgagcacg tctgaaaccc ctggtagccc cgacttcttt
1081 ttaattaaaa taaggtaagc ccttcaattt
//